Cell SurvivalReceptors, Death DomainApoptosisMyeloid Cell Leukemia Sequence 1 ProteinSurvival RateProto-Oncogene Proteins c-bcl-2Transcription Factor CHOPbcl-X ProteinCell Line, TumorTNF-Related Apoptosis-Inducing LigandDisease-Free SurvivalReactive Oxygen SpeciesSurvivalSignal TransductionProto-Oncogene Proteins c-aktSurvival AnalysisGraft SurvivalTreatment OutcomeTime FactorsKaplan-Meier EstimateRetrospective StudiesNeoplasm StagingProportional Hazards ModelsFollow-Up StudiesCell ProliferationCells, CulturedAntineoplastic Combined Chemotherapy ProtocolsAntineoplastic AgentsCombined Modality TherapyCell DeathPrognosisLung NeoplasmsBreast NeoplasmsImmunohistochemistryMice, Inbred C57BLPhosphorylationProto-Oncogene ProteinsPhosphatidylinositol 3-KinasesCell LineNeoplasm Recurrence, LocalProtein-Serine-Threonine KinasesMultivariate AnalysisMice, KnockoutBlotting, WesternRNA, Small InterferingAdenocarcinomaTumor Markers, BiologicalGene Expression Regulation, NeoplasticNeoplasm MetastasisMutationNeoplasmsCisplatinDisease Progressionbcl-Associated Death ProteinReverse Transcriptase Polymerase Chain ReactionEnzyme ActivationBrain NeoplasmsRisk FactorsMice, TransgenicCaspase 3Cell DivisionLiver NeoplasmsProspective StudiesCell DifferentiationRNA, MessengerCohort StudiesTumor Cells, CulturedModels, BiologicalTransfectionDoxorubicinDose-Response Relationship, DrugChemotherapy, AdjuvantDisease Models, AnimalAutophagyCaspasesTumor Suppressor Protein p53NF-kappa BCarcinoma, Squamous CellUp-RegulationLymphatic MetastasisAge FactorsRNA InterferenceCarcinoma, Non-Small-Cell LungColorectal NeoplasmsApoptosis Regulatory ProteinsEnzyme InhibitorsGene Expression RegulationMice, Inbred BALB CFluorouracilDrug Resistance, NeoplasmDNA-Binding ProteinsIn Situ Nick-End LabelingGlioblastomaPancreatic NeoplasmsNeoplasm InvasivenessCyclophosphamideTransplantation, HomologousMelanomaMicrobial ViabilityNeurons