• Heavy ion beams are an extremely promising treatment method because they are more effective than any other treatment for radioresistant tumors. (gsi.de)
  • The goal of HITRIplus is to improve heavy ion therapy as a cutting-edge tool to treat those tumors that are not curable with X-rays or protons, and that have better survival rates, lower recurrence or milder toxicity with ions. (gsi.de)
  • Although the procedure is a well-established treatment modality for organ-confined clinical stage T1-2 renal tumors that are not treatable by nephron-sparing surgery, its role in the management of higher-stage tumors, although, is not yet established. (urologytimes.com)
  • This leads to fewer side effects and enhances local control of tumors and thus survival. (uib.no)
  • Her special interest is treatment individualization and optimization of patients with brain tumors and tumors of the skull base, gastrointestinal malignancies as well as childhood cancer. (uib.no)
  • Patients were monitored for toxicity, response according to response evaluation criteria in solid tumors (RECIST) criteria, and survival. (omicsdi.org)
  • Cox regression was performed to compare liver metastases-free survival of patients with a nonfunctioning pancreatic neuroendocrine tumors versus those with an insulinoma and to identify factors associated with liver metastases-free survival. (omicsdi.org)
  • Inhibition of Hsp90 has broad therapeutic potential for the treatment of patients with solid tumors and blood-related cancers, including cancers that are resistant to other drugs. (salesandmarketingnetwork.com)
  • The only NSCLC subgroup that has a better than 50% five-year survival is that comprised of patients with peripherally located T1 or T2 tumors without evidence of nodal or distant metastases. (cancernetwork.com)
  • Research suggests that surgery to remove tumors is the most effective treatment for early-stage lung cancer. (mountsinai.org)
  • Doctors prefer P/D because it spares the healthy lung while still removing most of the mesothelioma tumors. (pintas.com)
  • Proton therapy is one of the most technologically advanced ways to deliver radiation treatments to cancerous tumors. (covenanthealth.com)
  • Proton therapy enables physicians to precisely determine the shape, size, depth and dose of treatment to effectively treat tumors while avoiding and eliminating damage to nearby healthy organs and tissues. (covenanthealth.com)
  • The FDA provided clearance for the TomoTherapy technology in 2002 and in 2016 for the Radixact System, the next-generation TomoTherapy platform, for the treatment of tumors anywhere in the body, including the full spectrum of head and neck cancers. (radixact.com)
  • Radixact helical delivery also enables treatment of a full range of diseases, including larger, more complex tumors, multiple tumors and recurrent tumors. (radixact.com)
  • A recent cohort study [ 3 ] evaluated the effect of fertility-sparing surgery in women with borderline ovarian tumors. (medscape.com)
  • Because borderline ovarian tumors are diagnosed in younger women, future health related to ovarian hormones as well the patient's reproductive needs have to be considered when treatment is discussed. (medscape.com)
  • von Hippel-Lindau (VHL) disease, or von Hippel-Lindau syndrome, is a rare genetic disorder characterized by visceral cysts and benign tumors in multiple organ systems that have subsequent potential for malignant change. (medscape.com)
  • Tumors involving other organs and the CNS (brain, spinal cord) are present in 25% of patients with VHL disease. (medscape.com)
  • Depending on the type of tumor, radiation therapy (RT) is either an essential complementary and supportive treatment before or after surgery or a clear treatment alternative to surgery. (uib.no)
  • Accuray Incorporated (Nasdaq: ARAY), is a radiation oncology company that develops, manufactures and sells precise, innovative tumor treatment solutions that set the standard of care with the aim of helping patients live longer, better lives. (geriatriccareers.com)
  • Currently, there is no standardized staging system or established therapeutic protocols for PM. Treatment options depend on the tumor stage and can involve radical or organ-sparing surgery. (biomedcentral.com)
  • Due to the deteriorating life quality triggered by the penile lesion, the initial treatment approach involved an urgent surgical removal of the penile tumor and the palpable inguinal lymph nodes. (biomedcentral.com)
  • In preclinical studies, Hsp90 and the Hedgehog pathway appear to be implicated in the growth and survival of a broad range of blood-related and solid tumor types. (salesandmarketingnetwork.com)
  • IPI-504 preferentially targets and accumulates in tumor tissues, sparing healthy tissues. (salesandmarketingnetwork.com)
  • Sparing these normal tissues permits the delivery of higher-radiation doses to the tumor. (cancernetwork.com)
  • By providing real-time continuous tracking of the tumor and organs-at-risk, MRIdian enables automatic gating of the radiation, turning the beam off if the target moves outside user-defined margins. (axisimagingnews.com)
  • Because of the progress with molecular targeted therapies, it is crucial to make a molecular characterization of the tumor before a treatment decision is made. (mountsinai.org)
  • A beam of high-energy protons is delivered with pin-point accuracy to the exact size, shape and depth of the tumor to kill the cancer while sparing healthy tissue in the area from unnecessary radiation, therefore decreasing the risk of side-effects. (covenanthealth.com)
  • Treatment with TomoHelical also enabled delivery of significantly reduced doses of radiation outside the tumor, leading to better acute salivary function than with VMAT. (radixact.com)
  • Integrated imaging and advanced dose-delivery capabilities enable your treatment team to create a more personalized treatment plan and confidently deliver the most precise dose of radiation, directly to the tumor. (radixact.com)
  • The researchers saw no differences in treatment responses related to age, tumor stage, type of mesothelioma or lymph node involvement. (survivingmesothelioma.com)
  • A team of medical researchers in Italy have achieved what they are calling "excellent" tumor control and survival results in malignant pleural mesothelioma patients using a combination of surgery, chemotherapy, and radiotherapy. (survivingmesothelioma.com)
  • To spare normal tissues (such as skin or organs which radiation must pass through in order to treat the tumor), shaped radiation beams are aimed from several angles of exposure to intersect at the tumor, providing a much larger absorbed dose there than in the surrounding, healthy tissue. (medicalmarijuana.com)
  • Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival. (cancercentrum.se)
  • She was trained as a radiation oncologist in Heidelberg, where she specialized in high-precision radiotherapy such as radiosurgery, stereotactic treatments, Intensity Modulated Radiotherapy (IMRT) as well as particle therapy. (uib.no)
  • It was reported that IMRT has fewer significant skin and gastrointestinal (GI) side-effects, which can limit anal cancer treatment. (ecancer.org)
  • IMRT is specifically designed to focus on the tumour only, sparing surrounding healthy tissue. (ecancer.org)
  • In contrast to two- or three-dimensional conventional radiation fields, which indiscriminately treat normal organs, IMRT is a novel technology that conforms or "paints" the radiation dose to the tumour and lymph node regions, while sparing healthy surrounding tissues. (ecancer.org)
  • Improvements in treatment-related toxicity have already been described in patients with breast, head and neck and prostate cancers treated with IMRT, as compared to conventionally-delivered radiation therapy. (ecancer.org)
  • Previous studies demonstrated the superiority of IMRT over the conventional radiation techniques for WPRT in sparing of organs at risk [9] and superior target coverage [10]. (scirp.org)
  • Three [iv] treatment planning simulation studies incorporating the multileaf collimator of the new CyberKnife M6™ System found consistent reductions in treatment time for both radiosurgery and IMRT plans, with equivalent or improved plan quality relative to the prior circular collimator plans or IMRT plans generated for other radiotherapy systems. (geriatriccareers.com)
  • Clinicians compared TomoTherapy System treatment plans for oropharyngeal cancer (a complex disease requiring the delivery of different doses to different targets in the head and neck region while sparing multiple organs-at-risk) to those generated for conventional IMRT plans. (radixact.com)
  • A retrospective, single center study of patients with locally advanced nasopharyngeal cancer (NPC) found those treated with the TomoTherapy System experienced better quality of life, such as salivary sparing compared to patients treated using a conventional IMRT system. (radixact.com)
  • These characteristics make this form of radiotherapy an excellent choice for the treatment of tumours located next to critical structures such as the spinal cord, eyes, and brain, as well as for paediatric malignancies. (nature.com)
  • Biochemical recurrence-free survival (bRFS), metastatic-free survival (MFS) and overall survival (OS) were assessed using Kaplan-Meier method. (bvsalud.org)
  • New research into the treatment of gastrointestinal cancers - and novel ways to predict recurrence and response were highlighted at the American Society of Clinical Oncology's annual Gastrointestinal Cancers Symposium (January 20-22, 2011, San Francisco). (ecancer.org)
  • These cancer cells cannot be treated with surgery alone and require systemic treatment to decrease the chance of cancer recurrence. (yourcancercare.com)
  • Radiation oncologists must often decide between delivering a large enough dose to control the tumour and sparing nearby organs from damage. (ebeam4therapy.eu)
  • Once there, the treatment can be applied directly and precisely to the tumour. (europa.eu)
  • For IO radiotherapy, because the treatment is applied directly to the tumour, radiation damage to surrounding healthy tissues is much reduced. (europa.eu)
  • Increasing tumour size is associated with a higher risk of muscle-invasive and/or non-organ-confined disease, both in ureteral and renal pelvis UTUC. (uroweb.org)
  • Kirrander P, Sherif A, Friedrich B, Lambe M, Hakansson U, steering committee of the Swedish National Penile Cancer R. The Swedish National Penile Cancer Register: Incidence, Tumour Characteristics, Management and Survival. (cancercentrum.se)
  • Advances in treatment using targeted biological therapies may further improve treatment outcomes. (medscape.com)
  • Her current research is focused on surgical airway education, functional and survival outcomes in patients with head and neck cancer, and quality improvement in delivery of head and neck cancer care. (yale.edu)
  • We develop a safe and cost effective approach to radiation therapy to enhance therapeutic efficacy and treatment accessibility providing improved outcomes and a better quality of life for patients. (ebeam4therapy.eu)
  • This may lead to poor clinical outcomes and suboptimal survival rates. (ebeam4therapy.eu)
  • Another study [vi] presented long-term outcomes of post-operative helical TomoTherapy treatment of malignant pleural mesothelioma. (geriatriccareers.com)
  • LAP-ABLATE will evaluate the combination of chemotherapy and MRI-guided ablative dose radiation therapy to determine MRIdian's role in improving overall survival outcomes and expanding the treatment options for patients with locally advanced disease. (axisimagingnews.com)
  • [ 4 ] Clinical outcomes differ by histologic subtype with 5-year overall survival rates ranging from 30% in DLBCL to 79% in marginal zone lymphoma. (medscape.com)
  • This treatment results in long-term disease-free survival, but is associated with significant acute toxicity due in part to the large radiation fields used. (ecancer.org)
  • The studies showed the breadth and depth of the TomoTherapy System as an efficient treatment option for a wide range of patients and disease types clinically proven to provide strong disease control and low incidence of toxicity. (geriatriccareers.com)
  • If the liver is the only site of metastatic disease, regional treatment options can offer the benefit of high local exposure with limited systemic toxicity, especially for patients without (further) systemic treatment options. (omicsdi.org)
  • The study also showed that TomoHelical treatments resulted in generally mild acute and late toxicity. (radixact.com)
  • No patient required cystectomy for treatment-related toxicity. (urotoday.com)
  • In the absence of confirmed organ dysfunction, unacceptable treatment-related toxicity, or withdrawal of consent, patients may receive NEOD001 for. (holyexperiment.org)
  • In particular, drug delivery is impaired by the blood-brain barrier, and cerebral toxicity limits the use of treatment modalities. (medscape.com)
  • GICS 2023 SUNLIGHT: New Standard of Care in Refractory Metastatic CRC The SUNLIGHT trial results show that adding bevacizumab to trifluridine/tipiracil (Lonsurf) improves median overall and progression free survival without increasing the risk for serious adverse events. (medscape.com)
  • GICS 2023 Adding SBRT to Sorafenib Boosts Survival in Liver Cancer Adding stereotactic body radiation therapy (SBRT) to treatment with sorafenib improved overall survival and progression-free survival as well as quality of life. (medscape.com)
  • The aim of HITRIplus is to integrate pre-clinical and clinical research in cancer treatment with heavy ion beams while jointly developing its high technology. (gsi.de)
  • The most important tool in the care of the patient with SLE is careful and frequent clinical and laboratory evaluation to tailor the medical regimen and to provide prompt recognition and treatment of disease flares. (medscape.com)
  • In the future, laparoscopy and open surgery will coexist in a synergistic fashion to provide the most effective and the least invasive treatment for a specific clinical situation. (urologytimes.com)
  • The Collaborative Ocular Melanoma Study introduced into clinical practice a standardised procedure that allowed the equivalence of IRT with enucleation in terms of overall survival to be demonstrated. (cun.es)
  • An ongoing GETUG-AFU-18 phase III trial is evaluating the impact of dose escalation in combination with 3-year androgen deprivation treatment on 5-year biochemical or clinical control in high-risk prostate cancer patients [8]. (scirp.org)
  • At PanCAN we support patient involvement in clinical trials as a way to gain access to some of the best treatment options and most cutting-edge approaches. (axisimagingnews.com)
  • To date, there are still no prospective randomized trials to clinical management, although they have an excellent prognosis, with a 5-year overall survival rate of almost 100% in early-stage disease (stage I-II) and between 86% and 92% in more advanced disease (stage III-IV). (intechopen.com)
  • The primary efficacy endpoints included pathological complete response (pCR), major pathological response (mPR), and the rate of clinical to pathological downstaging after neoadjuvant treatment. (bmj.com)
  • Together, they will explore and demonstrate how next generation IO imaging techniques can be applied to cancer research and treatment, from laboratory studies to clinical trials. (europa.eu)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • We investigated the efficacy and safety of mepolizumab 100 mg in idiopathic HES (I-HES) patients as a steroid sparing strategy for disease remission maintenance by assessing clinical conditions, blood eosinophil count (BEC) and adverse events at baseline and at 3-6-12 months follow-up. (biomedcentral.com)
  • overlap HES, including single-organ eosinophilic disorders (i.e. eosinophilic gastrointestinal disease, eosinophilic pneumonia) and distinct eosinophilic conditions overlapping with HES in their clinical presentation (i.e. (biomedcentral.com)
  • In the ensuing 25 years, the epidemiology, virology, pathophysiology, clinical course, and treatment of hantavirus pulmonary syndrome have been the focus of ongoing research. (cdc.gov)
  • Because VHL disease is a multiple-organ disease that widely varies in clinical presentation, various manifestations may lead to diagnosis. (medscape.com)
  • Molecular pathology and clinical treatment of independent HPV primary serous carcinoma of the uterine cervix (USCC): A case report. (cdc.gov)
  • more than one port may be required with protons if adequate skin sparing is to be achieved in patients being treated to high doses with only protons. (nature.com)
  • Early treatments were performed with photon radiotherapy. (uib.no)
  • Explained Dr. Lin, "Our analysis contributes further support to the use of organ preservation through a combination chemotherapy/radiotherapy as a viable option in the management of muscle-invasive bladder cancer. (thebioconnection.com)
  • 3-6] Most innovative techniques have focused on conformal treatment delivery with computer assisted three-dimensional therapy planning and, in some cases, intensity-modulated radiotherapy in which more complex treatment planning and delivery can allow the radiation oncologist to have better control of doses to healthy tissues. (cancernetwork.com)
  • Conventional chemotherapy plus non-ablative radiotherapy has not demonstrated improvements to overall survival. (axisimagingnews.com)
  • Of course, the risk of second malignancy is also a risk in adults, but the fact that the median age of adult cancer patients at diagnosis is in the seventh decade, that second malignancies after radiotherapy are uncommon in adults, and that they usually manifest 10-15 years after treatment make them less of a concern. (nature.com)
  • IO can be used to deliver diverse types of cancer treatments, including surgery, radiotherapy, chemotherapy and immunotherapy. (europa.eu)
  • Polyarteritis nodosa (PAN) is a systemic necrotizing inflammation of blood vessels (vasculitis) affecting medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but generally sparing the lungs' circulation. (wikipedia.org)
  • The researchers found that the women were most concerned about radiation damaging internal organs or burning their skin. (baptisthealth.net)
  • Therefore, chemotherapy often affects the body's normal tissues and organs, which can result in complications or side effects. (yourcancercare.com)
  • Furthermore, while many current treatments are effective at killing off cancer cells, they also cause a lot of harm to healthy cells, tissues and organs, resulting in a range of serious side effects for patients. (europa.eu)
  • Dr. Roche utilizes a collaborative approach when caring for patients using the most effective, patient-specific treatment options for benign and malignant diseases affecting the ear, sinuses, larynx, pharynx, oral cavity, thyroid and parathyroid glands, and salivary glands, while emphasizing our organ-sparing mission. (yale.edu)
  • The kidneys are two bean-shaped organs, each about the size of a fist. (healthline.com)
  • For children with renal disease, recognition of the steroid-sparing effect of immunosuppressive agents, such as azathioprine, mycophenolate, and cyclophosphamide, has greatly improved kidney organ survival and outcome. (medscape.com)
  • Treatment for renal cell cancer is tailored to each individual and may include surgery, precision cancer medicines, immunotherapy and/or chemotherapy. (yourcancercare.com)
  • Radiation therapy is not typically used for the treatment of renal cell cancer. (yourcancercare.com)
  • Partial nephrectomy, which is removal of only the cancer and a small border of normal tissue, is the standard treatment for the smallest cancers however patients will require a radical nephrectomy, or removal of the entire kidney for larger renal cell cancers. (yourcancercare.com)
  • Early identification of VHL is important because of the increased risk of serious complications (eg, renal cell carcinoma) to foster more effective treatment options and better prognoses. (medscape.com)
  • New data suggest that a computerized artificial intelligence system enhances the accuracy of treatment response assessments in patients with muscle-invasive bladder cancer. (medpagetoday.com)
  • A computerized artificial intelligence (AI)-based decision support system (CDSS-T) was developed in an effort to enhance the accuracy of treatment response assessments in patients with muscle-invasive bladder cancer. (medpagetoday.com)
  • Traditionally, treatment for muscle-invasive bladder cancer is chemotherapy followed by the removal of the patient's entire bladder, known as a radical cystectomy. (thebioconnection.com)
  • EPP is a much more invasive surgical treatment, often conducted in the cancer's more advanced stages. (pintas.com)
  • In a large Dutch series of UTUC, 5-year CSS was 86% for non-muscle-invasive tumours, 70% for muscle-invasive organ-confined tumours and 44% for locally-advanced tumours [ 27 ]. (uroweb.org)
  • Whether organ-conserving treatment by combined-modality therapy (CMT) achieves comparable long-term survival to radical cystectomy (RC) for muscle-invasive bladder cancer (BCa) is largely unknown. (urotoday.com)
  • Observing the small numbers of patients who have durable remissions with trimodal treatment, and the many negative side effects, the Swiss team concluded that less invasive approaches such as lung-sparing pleurectomy/decortication may be a better approach for most mesothelioma patients. (survivingmesothelioma.com)
  • Newer research indicates that other graft-versus-host disease target organs include the immune system (the hematopoietic system , e.g., the bone marrow and the thymus ) itself, and the lungs in the form of immune-mediated pneumonitis . (wikipedia.org)
  • Malignant mesothelioma is a cancer that starts in the membranes around organs, most often the lungs. (survivingmesothelioma.com)
  • Model training was conducted on two distinct multicenter datasets for the endpoints loco-regional control (LRC) and progression-free survival (PFS), respectively. (bvsalud.org)
  • In a Phase III trial, The Radiation Therapy Oncology Group (RTOG) showed improved progression-free survival (PFS) for high-risk prostate cancer patients treated with Whole Pelvis Radiation Therapy (WPRT) compared with prostate-only radiation therapy (PORT) [4]. (scirp.org)
  • Progression free survival (PFS) and overall survival (OS) were analyzed from time of first LR using Kaplan-Meier method. (stanfordchildrens.org)
  • One of the strategies designed to improve the survival rate of patients with bladder cancer and decrease the probability of progression to metastatic disease includes administering neoadjuvant chemotherapy prior to radical cystectomy. (medpagetoday.com)
  • Because of the toxicities inherent in neoadjuvant therapy, accurately evaluating treatment response to chemotherapy is critical to spare the patient from exposure to unnecessary chemotherapy or to determine whether to de-escalate the surgical plan from cystectomy to organ preservation therapy. (medpagetoday.com)
  • Treatment response was evaluated by 17 observers from 6 specialties and 4 institutions using pre- and post-chemotherapy CT urography scans, both with and without CDSS-T, from 123 patients. (medpagetoday.com)
  • However, Beaumont researchers have data suggesting that treatment consisting of limited surgery followed by combination chemotherapy and radiation is just as effective, while allowing patients to keep their bladder and maintain function. (thebioconnection.com)
  • Chemotherapy is any treatment involving the use of drugs to kill cancer cells. (yourcancercare.com)
  • The study is designed to demonstrate superior overall survival in patients receiving post-chemotherapy MRIdian SMART. (axisimagingnews.com)
  • While prior studies of chemotherapy plus non-ablative radiation have not shown an improvement over chemotherapy alone for patients with LAPC, we believe MRIdian's advanced capabilities overcome the many limitations of other radiation treatment modalities. (axisimagingnews.com)
  • Similarly, for chemotherapy, the precise delivery of the treatment means that higher doses can be used because healthy tissues will not be exposed to the treatment. (europa.eu)
  • Most doctors recommend a multi-modal treatment strategy, which combines traditional options such as surgery, chemotherapy, and radiation. (pintas.com)
  • Organ response rates compared favorably with those reported previously for chemotherapy. (holyexperiment.org)
  • The DVH analysis showed good coverage of PTVs and organs at risk doses were acceptable. (scirp.org)
  • In studies spanning more than four decades, Rubin and several collaborators identified the clinicopathologic courses of radiation injury in organs and tissues throughout the body and identified tolerance doses for those organs. (cancernetwork.com)
  • Ablative doses with MRIdian SMART can provide pancreatic cancer patients a clinically meaningful improvement in long-term survival while maintaining an excellent quality of life and rarely causing significant side effects. (axisimagingnews.com)
  • Of the 61 TomoTherapy presentations, several focused on treatment of breast, head and neck, prostate, and lung cancers. (geriatriccareers.com)
  • These cancers are quite unique and, in my opinion, knowledge of their physiology and treatment options is essential," she said. (myesr.org)
  • Brachytherapy, in which a radiation source is placed inside or next to the area requiring treatment, is another form of radiation therapy that minimizes exposure to healthy tissue during procedures to treat cancers of the breast, prostate and other organs. (medicalmarijuana.com)
  • Neural-network-based outcome predictions may enable further treatment personalization of patients with head and neck cancer. (bvsalud.org)
  • New research shows that, compared with environmental-related head and neck squamous cell carcinomas, patients with HPV-related malignancies display a better response to treatment and a lower risk of death and progression, Dr. Trojanowska pointed out. (myesr.org)
  • This makes Radixact treatment an excellent option for medically inoperable head and neck cancer patients, those seeking an alternative to surgery, or those for whom radiation therapy is recommended as a complementary treatment to traditional surgery. (radixact.com)
  • In a related study [vii] , authors confirmed in patients with malignant pleural mesothelioma that either adjuvant conventionally fractionated or definitive hypofractionated TomoTherapy treatment results in a high prescription dose to the treatment volume while sparing organs at risk. (geriatriccareers.com)
  • The ion beam focuses on the malignant tissue while sparing the healthy organs. (gsi.de)
  • This method spares normal brain tissue and hence lowers the risk for side effects, especially for lesions that have complex shapes or are close to neighboring healthy organs. (uib.no)
  • This allows for precise delivery of the prescribed dose to the target while sparing surrounding healthy tissue and critical structures. (axisimagingnews.com)
  • The IMAGIO project focuses on an approach called interventional oncology (IO) which targets cancer cells more precisely, thereby sparing healthy cells from the toxic effects of many treatments. (europa.eu)
  • Reducing or eliminating unnecessary radiation to healthy tissue improves quality of life during and after treatment by reducing the side effects. (covenanthealth.com)
  • This makes eliminating unnecessary radiation and sparing healthy tissue as much as possible important to avoid long-term side effects. (covenanthealth.com)
  • Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs. (medicaldaily.com)
  • The primary safety endpoint was unplanned delay in surgery considered to be at least possibly related to neoadjuvant treatment. (bmj.com)
  • Results Twenty-one patients underwent neoadjuvant treatment, which was well tolerated and did not delay surgery, thus meeting the primary endpoint. (bmj.com)
  • 70% of patients while offering long-term survival rates comparable to contemporary cystectomy series. (urotoday.com)
  • Median disease-free survival was 6.6 months with a median overall survival of 10.0 months. (omicsdi.org)
  • In the SIERRA trial, patient-specific dosimetry was used to generate an individualized therapeutic dose to target marrow and spare non-hematopoietic organs. (onclive.com)
  • Hsp90 is an emerging therapeutic target of interest for the treatment of cancer. (salesandmarketingnetwork.com)
  • Various photon radiation techniques have been tried in order to effect a therapeutic advantage, among them hyperfractionation (multiple treatments per day), accelerated fractionation (shorter treatment periods), and dose escalation. (cancernetwork.com)
  • It may also be used as palliative treatment (where cure is not possible and the aim is for local disease control or symptomatic relief) or as therapeutic treatment (where the therapy has survival benefit and it can be curative). (medicalmarijuana.com)
  • Dual Immunotherapy Promising New Option for Liver Cancer The combination of durvalumab plus the experimental drug tremelimumab significantly improved overall survival as compared to sorafenib. (medscape.com)
  • Precision immunotherapy treatment of cancer has also progressed considerably over the past few decades and has now become a standard treatment. (yourcancercare.com)
  • We use a broad range of standard and state-of-the-art treatment options including surgery, radiation, medical oncology, including molecular targeted therapies, and immunotherapy. (mountsinai.org)
  • Esteemed mesothelioma institutes such as the Pacific Meso Center perform P/D on nearly every patient, followed by radiation and a long-term therapy program usually involving immunotherapy and experimental treatments. (pintas.com)
  • Conventional radiation therapy, which utilises photon (X-ray) beams, is frequently used in the locoregional treatment of cancer. (nature.com)
  • Similar to conventional radiation, proton therapy delivers a total prescribed dose of radiation planned by the radiation oncologist and split into a number of treatment sessions called fractions. (covenanthealth.com)
  • How is Radixact treatment different than conventional radiation therapy? (radixact.com)
  • Radixact treatments are completed in several weeks, similar to conventional radiation therapy. (radixact.com)
  • Although surgery is considered a potentially curative treatment for non-metastatic pancreatic cancer, less than 20 percent of patients are candidates. (axisimagingnews.com)
  • How is Radixact treatment different than surgery? (radixact.com)
  • Of the women in the UCLA study, 82 percent had breast-sparing surgery prior to radiation. (baptisthealth.net)
  • Surgery became less definitive, and new chemotherapeutic regimens and radiation therapy became more focused and less damaging for noninvolved organs. (medscape.com)
  • [ 2 ] In addition to the tools of assisted reproductive technology, increasing evidence suggests that fertility-sparing surgery is safe for many patients affected by cancer. (medscape.com)
  • Fertility-sparing surgery was performed on 112 patients. (medscape.com)
  • Due to the generally good prognosis of these cases, conservative surgery during which the uterus and/or ovary(ies) are spared can be considered. (medscape.com)
  • Survival, however, was not influenced by fertility-sparing surgery. (medscape.com)
  • Despite major advances in other oncology indications, treatment options for pancreatic cancer remain severely limited, including for patients with locally advanced disease," said Julie Fleshman, President and CEO of the Pancreatic Cancer Action Network (PanCAN). (axisimagingnews.com)
  • Radiation is currently delivered with substantially more precision than in the past because of advances in imaging and treatment planning. (nature.com)
  • The good news is that advances in treatments mean that survival rates are improving dramatically. (europa.eu)
  • But, according to Dr. Shaverdian, advances in recent years have allowed radiation oncologists to "spare critical organs, create an individual radiation plan for each patient and also deliver radiation in more convenient schedules. (baptisthealth.net)
  • Radiologists, oncologists, and urologists were considered to be physicians experienced in assessing bladder cancer treatment response, whereas radiology residents, neurology fellows, and medical students were all categorized as inexperienced physicians. (medpagetoday.com)
  • Overall, the accuracy of physicians in assessing bladder cancer treatment response was significantly improved by using CDSS-T compared with reading the CTU scans without CDSS-T. Mean area under the curve for all observers was 0.73 without CDSS-T and increased to 0.77 with the application of CDSS-T ( P =.002). (medpagetoday.com)
  • In the case of bladder cancer, we have good data to support organ-sparing therapy. (thebioconnection.com)
  • Our aim was to present a summary of the 2010 version of the European Association of Urology (EAU) guidelines on the screening, diagnosis, and treatment of clinically localised cancer of the prostate (PCa). (nih.gov)
  • Early diagnosis and careful treatment tailored to individual patient symptoms have improved the prognosis in what was once perceived as an often-fatal disease. (medscape.com)
  • Even with aggressive treatment, most mesothelioma patients do not live more than 12 to 18 months after diagnosis. (survivingmesothelioma.com)
  • [ 7 ] Responses to corticosteroids are not durable and thus only delay definitive diagnosis and treatment. (medscape.com)
  • Patients who have not started or completed childbearing not only have to face a diagnosis of cancer but have to consider remaining childless as a result of disease or its treatment. (medscape.com)
  • The wide age range and pleiotropic manner in which VHL disease presents complicates diagnosis and treatment in affected individuals, as well as their at-risk relatives. (medscape.com)
  • P/D enables patients to reserve physiological strength for further treatment options, while still removing the majority of cancerous cells from the chest. (pintas.com)
  • In men with locally advanced PCa in whom local therapy is not mandatory, watchful waiting (WW) is a treatment alternative to androgen-deprivation therapy (ADT) with equivalent oncologic efficacy. (nih.gov)
  • In the first article of this series, Nilay Gandhi, MD, explains the treatment and management of patients with advanced/metastatic prostate cancer and details the options for androgen deprivation therapy. (urologytimes.com)
  • Norway is establishing particle therapy centres for cancer treatment in Oslo and Bergen. (uib.no)
  • Particle therapy, in combination with molecular and digital biomarkers is revolutionizing cancer treatment. (uib.no)
  • We found that brachytherapy is a medically- and cost-effective treatment compared to external beam radiation therapy alone," said Daniel Krauss, M.D., Beaumont Hospital, Royal Oak radiation oncologist and one of the study authors. (thebioconnection.com)
  • Systemic therapy is any treatment directed at destroying cancer cells throughout the body. (yourcancercare.com)
  • Intensity-modulated proton therapy treatment was replanned on the simulation computed tomography scans for all breast cancer patients. (allenpress.com)
  • Cardiotoxicity studies evaluating conduction node exposure might define dose constraints and criteria for additional cardiac-sparing techniques, such as respiratory techniques or proton therapy, which could benefit patients with underlying rhythmic or conduction disorders. (allenpress.com)
  • Adjuvant breast radiation therapy is associated with increased locoregional control and patient-specific survival [ 1 ]. (allenpress.com)
  • What is proton therapy treatment? (covenanthealth.com)
  • The only certain way to know if proton therapy is the best option for your cancer treatment plan is to speak with a proton-experienced radiation oncologist. (covenanthealth.com)
  • Generally, if you have been diagnosed with cancer and radiation will be part of your treatment, then proton therapy may be right for you. (covenanthealth.com)
  • The proton therapy treatment team work to make your treatment as comfortable as possible. (covenanthealth.com)
  • Can proton therapy be combined with other treatment options? (covenanthealth.com)
  • Over 20% of patients taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, suffer from the rebound, compared to less than the 2% chance seen in other treatment groups, a Harvard Medical School study revealed. (medicaldaily.com)
  • Many prognostic factors have been identified and can be used to risk-stratify patients in order to decide on the most appropriate local treatment (radical vs. conservative) and discuss peri-operative systemic therapy. (uroweb.org)
  • These patients may be eligible for therapy deintensification or early pursuit of novel treatments/approaches that are desperately needed. (stanfordchildrens.org)
  • These results support modern bladder-sparing therapy as a proven alternative for selected patients. (urotoday.com)
  • The majority of patients who have radiation therapy for breast cancer say the treatment isn't as "scary" as they thought it would be, according to a recent study by researchers at the University of California, Los Angeles (UCLA). (baptisthealth.net)
  • Nine out of 10 patients agreed "if future patients knew the real truth about radiation therapy, they would be less scared about treatment," according to lead researcher Narek Shaverdian, M.D., who is chief resident of radiation oncology at UCLA's David Geffen School of Medicine. (baptisthealth.net)
  • Radiation therapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, and prevention of keloid scar growth, vascular restenosis , and heterotopic ossification. (medicalmarijuana.com)
  • The brachytherapy boost significantly lowered expected lifetime treatment costs because it decreased the incidence of metastatic prostate cancer, cutting the use of expensive targeted therapies. (thebioconnection.com)
  • For high risk prostate cancer, the treatment volumes and even dose levels are still a controversial issue. (scirp.org)
  • Drawing the dose volume histograms (DVHs) was done for planning target volumes (PTVs), including Prostate PTV & nodal PTV, and organs at risk including rectum, bladder, femoral heads, and bowel bag for the plans. (scirp.org)
  • This ability to spare normal tissues is an important consideration: The greater the extent to which the physician can reduce or eliminate the radiation dose to normal tissues, the lesser the likelihood that treatment will need to be compromised because of unacceptable side effects. (cancernetwork.com)
  • The Radixact System, the next-generation TomoTherapy® platform, has been designed to enable doctors to more effectively and efficiently deliver precise radiation treatments to more patients. (radixact.com)
  • We report interim results from the dose-escalation component of an ongoing, first-in-human, phase I/II dose-escalation/expansion study of NEOD001 in patients with AL amyloidosis and persistent organ dysfunction. (holyexperiment.org)
  • Active treatment is mostly recommended for patients with localised disease and a long life expectancy with radical prostatectomy (RP) shown to be superior to WW in a prospective randomised trial. (nih.gov)
  • Further trials are warranted to improve treatment and life expectancy of patients suffering from fatal diseases such as pancreatic carcinoma. (omicsdi.org)
  • Average Life Expectancy The age at which 50 percent of the members of a population have died, when plotted on a standard survival curve. (agemed.org)
  • For locally advanced disease, adjuvant ADT for 3 yr results in superior disease-specific and overall survival rates and represents the treatment of choice. (nih.gov)
  • Further studies have supported the notion that significantly escalating the radiation dose to an ablative range may improve overall survival. (axisimagingnews.com)
  • The local control rate and cancer-specific survival rate were significantly better in the TomoTherapy patient group than in the VMAT patient group. (radixact.com)
  • Cancer treatment has changed significantly over the past decades. (medscape.com)
  • Where can I get Radixact and TomoTherapy treatments? (radixact.com)
  • TomoTherapy treatments are available at hundreds of locations worldwide. (radixact.com)
  • Consideration should be given to the prevention of atherosclerosis and osteoporosis , because these are long-term consequences of SLE and its treatment. (medscape.com)
  • [6] Chronic graft-versus-host disease also attacks the above organs, but over its long-term course can also cause damage to the connective tissue and exocrine glands . (wikipedia.org)
  • Although this trimodal approach carries a high risk of serious complications and even death, it has resulted in long term survival for some mesothelioma patients. (survivingmesothelioma.com)
  • tients post-cone biopsy: results of a long-term carcinoma in situ: implications for treatment. (who.int)
  • We sought to investigate the efficacy and safety of mepolizumab 100 mg in I-HES patients as a steroid-sparing strategy for disease remission maintenance. (biomedcentral.com)
  • It was reported by Dr Nicholas Campbell (Oncology fellow, University of Chicago, Illinois) that while more than 80% of patients can be treated effectively with imatinib, resistance frequently develops, and other treatments are needed. (ecancer.org)
  • IMAGIO focuses on 'interventional oncology', which uses miniaturised instruments to target cancer cells more precisely, thereby sparing health cells. (europa.eu)
  • Mount Sinai physicians are skilled in providing the full range of lung cancer treatments. (mountsinai.org)
  • IO approaches allow patients to recover faster while also cutting the cost of treatment. (europa.eu)
  • It suggests that a personalized treatment dose might be explored according to the disease classification and activity at the time of biologic treatment start. (biomedcentral.com)
  • Brachytherapy patients were additionally shown to have an increase in quality adjusted life years, a measure taking into account both survival time as well as disease and treatment related impacts on quality of life, of 10.8 years vs. 9.3 years for patients receiving external beam radiation alone. (thebioconnection.com)
  • Mesothelioma lawyers at Pintas & Mullins Law Firm highlight two recent studies that compared these traditional modes of treatment to determine the best possible program to extend both survival time and quality of life for patients. (pintas.com)
  • Treatment with a targeted tyrosine kinase inhibitor (TKI), sorafenib, may be an effective alternative for patients with advanced gastrointestinal stromal tumours (GIST) that are resistant to standard therapies. (ecancer.org)
  • Although larger studies are needed, our report firstly describes that in a well-defined population, diagnosed with I-HES and in disease remission, low dose mepolizumab is a safe and effective steroid-sparing option for remission maintenance. (biomedcentral.com)
  • Traditionally, most T3 lesions have been treated with open radical nephrectomy, with 5-year survival rates in the 40% to 80% range. (urologytimes.com)
  • February 11, 2021 - Apamistamab conditioning treatment with targeted radioimmunotherapy to the bone marrow resulted in high rates of successful allogeneic hematopoietic stem cell transplants in patients with active, relapsed, or refractory acute myeloid leukemia. (onclive.com)
  • Apamistamab (Iomab-B) conditioning treatment with targeted radioimmunotherapy to the bone marrow resulted in high rates of successful allogeneic hematopoietic stem cell transplants in patients with active, relapsed, or refractory acute myeloid leukemia (AML), according to interim results from the phase 3 SIERRA trial, which were presented virtually at the 2021 Transplant and Cellular Therapies Meetings. (onclive.com)
  • In vivo, 2A4 promoted AL amyloid clearance in a mouse amyloidoma model by engaging phagocytes.9 Therefore, NEOD001 is hypothesized to directly target and clear light chain amyloid deposited in affected organs of patients with AL, with the potential to restore organ function. (holyexperiment.org)
  • It is the premier model to study the development of tubular organs, such as the human lung, kidney, and blood vessels. (bvsalud.org)
  • One [ii] study of lung SBRT with the CyberKnife System reported lower chest wall maximum dose when lesions were tracked with the Synchrony Respiratory Tracking System compared to static or linac-based treatment plans, and another study [iii] showed very low incidence of chest wall pain, a common side effect of lung SBRT for lesions near the chest wall. (geriatriccareers.com)
  • Durable CR (dCR) rate is the primary end point of the study, characterized as complete response at 6 months after initial CR, and the secondary end point is overall survival (OS) rate at 1 year. (onclive.com)
  • Treatment with a new class of drugs, called senolytics, in donors improved the physical fitness of the recipients, a new study has shown. (medicaldaily.com)
  • R, Flisberg P, Hedlund L, Östlund I, Bergkvist L. Impact of general anaesthesia on breast cancer survival: a 5-year follow up of a pragmatic, randomised, controlled trial, the CAN-study, comparing propofol and sevoflurane. (cancercentrum.se)
  • PAN may affect nearly every organ system and thus can present with a broad array of signs and symptoms. (wikipedia.org)
  • Mesothelioma is very different from most other cancer types because it manifests in a sheet of cancer cells covering nearly every organ and surface in the chest. (pintas.com)