AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
RecurrenceNeoplasm Recurrence, LocalSurvival RateCell SurvivalDisease-Free SurvivalSurvival AnalysisTreatment OutcomeSurvivalRetrospective StudiesFollow-Up StudiesGraft SurvivalPrognosisNeoplasm StagingTime FactorsKaplan-Meier EstimateCombined Modality TherapyProportional Hazards ModelsBreast NeoplasmsTumor Markers, BiologicalRisk FactorsLiver NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsLymphatic MetastasisMultivariate AnalysisProspective StudiesChemotherapy, AdjuvantNeoplasm MetastasisAdenocarcinomaCarcinoma, HepatocellularLung NeoplasmsImmunohistochemistryRadiotherapy, AdjuvantPredictive Value of TestsLiver TransplantationApoptosisCohort StudiesDisease ProgressionNeoplasm InvasivenessAntineoplastic AgentsPostoperative ComplicationsRisk AssessmentBrain NeoplasmsCarcinoma, Squamous CellRectal NeoplasmsColorectal NeoplasmsProstatic NeoplasmsBone NeoplasmsCell Line, TumorHepatectomyReoperationCatheter AblationAge FactorsTomography, X-Ray ComputedUrinary Bladder NeoplasmsCarcinomaSignal TransductionIncidenceMastectomy, SegmentalSarcomaActuarial AnalysisGene Expression Regulation, NeoplasticLymph Node ExcisionProstatectomyNeoplasm GradingFluorouracilCisplatinRegistriesCell ProliferationMelanomaDoxorubicinDrug Administration ScheduleNeoadjuvant TherapyCarcinoma, Non-Small-Cell LungMastectomyStomach NeoplasmsSoft Tissue NeoplasmsCyclophosphamideSkin NeoplasmsGraft RejectionOvarian NeoplasmsRadiotherapy DosageTransplantation, HomologousRadiotherapySalvage TherapyNeoplasmsProbabilityHead and Neck NeoplasmsMutationTreatment FailureReceptors, EstrogenChi-Square DistributionRandomized Controlled Trials as TopicRemission InductionMice, Inbred C57BLLymph NodesGlioblastomaPancreatic NeoplasmsCurettageLife TablesNeoplasm Seeding
Tumor recurrenceLocal recurrencePatientsResectionRegional recurrenceMetastasisDistantMortalityPatternsLong-term survivalPrimary endpointClinicalRateRiskRacial DisparitiesBreastOutcomesNodalSignificantly decreasedPrognosticAdjuvantProgressionOvarianCurativeNSCLCMastectomyChemotherapyKaplan-MeierFree survivalIncidenceDiseaseCirculatingAndrogen deprivation therapy2017LikelihoodTreatment2023RatesProliferationInvasionTreatments
Tumor recurrence11
Local recurrence6
Patients44
  • These investigators had previously demonstrated that financial difficulties impact survival in patients with head and neck cancer, as well as that financial counseling can benefit these patients. (medpagetoday.com)
  • Recurrence occurred in 336 patients. (lu.se)
  • Overall, per patient treated for recurrence remaining alive with no evidence of disease, the number of FU images needed was 542, and 697 for high-risk patients. (lu.se)
  • In a seven-year follow up of 2,413 breast cancer patients, ages 24 to 70, who did not have diabetes, 390 developed a recurrence of their breast cancer. (drmirkin.com)
  • A randomized, placebo-controlled, double-blinded pilot trial was conducted, comparing the effects of Brassica consumption and indole-3-carbinol supplements on PSA among prostate cancer patients with PSA recurrence following prostectomy. (aicr.org)
  • Overall, median survival of patients with LOH was less than half (19 vs. 41 months, p = 0.036, stratified on stage) than those without loss. (mssm.edu)
  • We investigated the relationship between nodal stage and local-regional recurrence (LR), distant recurrence (DR) and overall survival (OS) for patients having an R0 resection. (psu.edu)
  • Therefore, in this study, they reviewed medical records of 297 patients whose breast cancer was treated with NSM from June 2007 through December 2012, to analyze rates and patterns of recurrence. (news-medical.net)
  • Intrinsic Tumor Characteristics Related to Recurrence Risk and Overall Survival In Patients with Uveal Melanoma. (nesurgical.org)
  • To examine the association between clinical, histopathologic, and genomic factors and disease recurrence or mortality in patients with uveal melanoma. (nesurgical.org)
  • Disease recurrence was observed in 52% of patients until the last follow-up, with 80% of them having a first metastasis in the liver, followed by 7% in the lung, and 7% having a widespread metastatic disease at once. (nesurgical.org)
  • The median time to recurrence was 31 months (IQR: 17-51 months) and the median overall survival was 41 months (IQR: 23-68 months), with 70% of patients being alive until the date of last follow-up. (nesurgical.org)
  • For these patients, stereotactic body radiation therapy (SBRT) and recurrence surgery are optional treatments. (researchsquare.com)
  • A retrospective analysis of NSCLC patients who had undergone radical surgery at the Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) from November 2012 to December 2018 and had received SBRT or reoperation because of postoperative lung recurrence was performed. (researchsquare.com)
  • For patients with lung recurrence after radical NSCLC, no significant difference exists in the efficacy of SBRT and surgery. (researchsquare.com)
  • This study aimed to investigate the difference in efficacy between SBRT and reoperation in NSCLC patients with lung recurrence after radical surgery. (researchsquare.com)
  • patients whose recurrence was super-central and could not undergo SBRT. (researchsquare.com)
  • Prediction of local tumor control and recurrence-free survival in patients with pancreatic cancer undergoing curative resection after neoadjuvant chemoradiotherapy. (bvsalud.org)
  • Imlygic) was associated with a significant improvement in 5-year survival outcomes, including overall survival, compared with surgery alone in patients with advanced resectable melanoma , new data suggest. (medscape.com)
  • Patients are in need of new treatments that can improve survival outcomes, and these positive results support the potential of KEYTRUDA in combination with chemotherapy as a first-line treatment for patients with the most common form of malignant mesothelioma. (merck.com)
  • In the HNLT breast cancer patients (n = 73), the 5-year recurrence-free survival rate was significantly lower (57 %) in patients with positive expression of both Girdin and Ki-67 than the rate in other patients (92 %) (p = 0.002). (fujita-hu.ac.jp)
  • The expression status of Girdin and Ki-67 can be a useful biomarker in stratifying patients with HNLT breast cancer into those with high risk of recurrence and the need for additional chemotherapy. (fujita-hu.ac.jp)
  • Still, 70 to 80% of patients experience cancer recurrence within five years of receiving these treatments. (healthxchange.sg)
  • A total of 668 patients with HCC at high-risk of cancer recurrence after surgical resection or ablation were enrolled from 134 sites in 26 countries. (healthxchange.sg)
  • Thus, the authors retrospectively examined the link between propofol-based total intravenous anesthesia (TIVA) and recurrence or overall survival in patients undergoing modified radical mastectomy (MRM). (ekja.org)
  • Aim The aim of this study was to report the patterns of recurrence, locoregional control, and survival of patients diagnosed with endometrial adenocarcinomas over a 7-year period after reclassifying them under the recent ESMO-ESGO-ESTRO (European Society of Medical Oncology/European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology) consensus classification. (bmj.com)
  • Five patients received definitive EBRT + intracavitary brachytherapy because of surgical inoperability, four of whom are disease-free locoregionally with median overall survival of 33.8 months. (bmj.com)
  • Author and 14 year breast cancer survivor Musa Mayer breaks the silence surrounding recurrence to talk frankly about the feelings of uncertainty and fear that breast cancer patients commonly face when their treatment ends, and for years thereafter. (google.com)
  • The 1996 study, conducted at a single hospital in Milan, opened the door to liver transplants for people with HCC that is confined to the liver and "had a profound impact on the survival of liver cancer patients," Dr. Tabrizian said. (cancer.gov)
  • In the phase III EVEREST trial reported in The Lancet , Christopher W. Ryan, MD , and colleagues found that adjuvant everolimus was not associated with a significant improvement in event-free survival vs placebo in patients at high risk of disease recurrence following surgery for renal cell carcinoma. (ascopost.com)
  • In the U.S. multicenter double-blind trial, 1,545 patients who had undergone nephrectomy and were at an intermediate-high or very high risk of recurrence were randomly assigned between April 2011 and September 2016 to receive everolimus at 10 mg (n = 775) or placebo (n = 770) once daily for 54 weeks. (ascopost.com)
  • Benefit of everolimus was observed among patients at very high risk of recurrence. (ascopost.com)
  • The investigators concluded, "Postoperative everolimus did not improve recurrence-free survival compared with placebo among patients with renal cell carcinoma at high risk of recurrence after nephrectomy. (ascopost.com)
  • Background: Long-term outcomes of patients treated with salvage lymph node dissection (sLND) for nodal recurrence of prostate cancer (PCa) remain unknown. (uni-koeln.de)
  • Design, setting, and participants: The study included 189 patients who experienced prostate-specific antigen (PSA) rise and nodal-only recurrence after radical prostatectomy (RP) and underwent sLND at 11 tertiary referral centers between 2002 and 2011. (uni-koeln.de)
  • Results and limitations: At long term, 110 and 163 patients experienced CR and BCR, respectively, with CR-free and BCR-free survival at 10 yr of 31% and 11%, respectively. (uni-koeln.de)
  • I. To determine if the invasive disease-free survival (iDFS) with T-DM1 and tucatinib is superior to the iDFS in the control arm (T-DM1 + placebo) when administered to high risk patients with HER2-positive breast cancer and residual disease after neoadjuvant HER2-directed therapy. (orlandohealth.com)
  • Patients with positive lymph node status have worse survival after CRS-HIPEC, which is probably due to higher rates of systemic failure. (lu.se)
  • For treatment recommendations for patients with a life expectancy ≥20 y, see initial therapy for Low Risk of Recurrence, below. (medscape.com)
  • The risk of distant recurrence in breast cancer patients is difficult to prognostic indices, such as the Nottingham Prognostic Index (6, 7), assess with current clinical and histopathological parameters, and have proven valuable in identifying patients with poor prognosis. (lu.se)
  • In a study of stage I disease, all recurrences appeared in patients who were inadequately staged. (medscape.com)
  • Contexte: Pour contrôler la propagation de la maladie à coronavirus 19 (COVID-19) causée par le syndrome respiratoire aigu sévère coronavirus-2 (SRAS-CoV-2), il est nécessaire d'identifier et d'isoler de manière adéquate les patients infectieux, en particulier sur le lieu de travail. (bvsalud.org)
  • Patients in the standard arm (surgery alone) will undergo large en- bloc curative intent surgery will be performed within 4 weeks following randomization. (who.int)
  • The research focuses on developing novel prediction marker with therapeutic potential, to improve survival of colorectal cancer patients. (lu.se)
Resection2
Regional recurrence2
Metastasis4
Distant2
Mortality1
Patterns3
  • Conclusions Recurrence rates, survival rates, and the patterns of recurrence are comparable with published literature and partly validates the ESMO-ESGO-ESTRO consensus statement. (bmj.com)
  • Different chemotherapy timings did not differ significantly in either survival or recurrence patterns. (lu.se)
  • However, within and across cancers, biomarkers can identify heterogeneous subgroups associated with different risk factors, treatment responses, recurrences and survival patterns. (cdc.gov)
Long-term survival2
  • Data on long-term survival and recurrence after stroke are lacking. (nih.gov)
  • Long-term survival and recurrence varied substantially by first stroke cause. (nih.gov)
Primary endpoint1
  • The primary endpoint of the study is OS, and secondary endpoints include progression-free survival (PFS) and objective response rate (ORR) as assessed by blinded independent central review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 modified for mesothelioma, safety and quality of life. (merck.com)
Clinical2
  • The aims of the study are to compare male and female breast cancer (FBC) in terms of cancer clinical and anatomopathological features and treatment approach, and to identify differences between male BC and FBC in terms of survival. (mdpi.com)
  • Numerous clinical trials have shown that combining MMC administration with hypothermia can improve tumor ablation and prevent recurrence post-TUR. (spandidos-publications.com)
Rate11
  • People with oligodendrogliomas have a higher survival rate than most other brain tumors. (healthline.com)
  • Women with breast cancer who undergo nipple-sparing mastectomy (NSM) have a low rate of the cancer returning within the first five years, when most recurrences in the breast are diagnosed, findings of a single-center study show. (news-medical.net)
  • Their recurrence rate, she said, is comparable to reported rates of disease recurrence after standard mastectomy. (news-medical.net)
  • According to older research that set the standard for treatment recommendations, the rate of recurrence for people who chose a lumpectomy is about the same as the rate of recurrence for people who undergo a mastectomy. (medicalnewstoday.com)
  • The type of breast cancer can affect the recurrence rate. (medicalnewstoday.com)
  • Propofol group showed a lower rate of cancer recurrence (P = 0.037), with an estimated hazard ratio of 0.550 (95% CI 0.311-0.973). (ekja.org)
  • Although, the recurrence rate of NMIBC is significantly decreased by TUR in combination with intravesical chemotherapy, the rate of cancer progression is not diminished ( 7 - 12 ). (spandidos-publications.com)
  • A 10-year survival rate of more than 50% "is considered a great cure rate for liver cancer," said Laura Kulik, M.D., of Northwestern Memorial Hospital in Chicago, who was not involved in the new study. (cancer.gov)
  • The survival rate is a standard factor to discuss the patient's prognosis. (news-medical.net)
  • with no evidence of difference in PFS, OS and systemic recurrence rate by timing of systemic chemotherapy. (lu.se)
  • Despite methodological differences, findings evidence that although IBC presents particular features (lower survival rate and worse prognostics than most types of breast cancer), very few studies examine its epidemiology and specific risk factors in depth and use any other therapeutic approaches than those commonly used for other breast cancer subtypes. (bvsalud.org)
Risk12
  • New results from the WHEL (Women's Healthy Eating and Living) Study show that women who did not eat for at least 13 hours at night (6PM to 7AM) had a 36 percent lower risk of cancer recurrence ( JAMA Oncology , published online March 31, 2016). (drmirkin.com)
  • The authors of this new study state that 'Randomized trials are needed to adequately test whether prolonging the nightly fasting interval can reduce the risk of chronic disease' (in this case, breast cancer recurrence). (drmirkin.com)
  • We champion the latest and most authoritative scientific research from around the world on cancer prevention and survival through diet, weight and physical activity, so that we can help people make informed lifestyle choices to reduce their cancer risk. (aicr.org)
  • A sensitivity analysis with competing risk analysis for time trends in recurrence were performed. (nih.gov)
  • According to the breast cancer charity Susan G. Komen , everyone who has had breast cancer has a risk of recurrence. (medicalnewstoday.com)
  • In a 2017 study , researchers found that people with estrogen-receptor (ER)-positive breast cancer had a persistent risk of recurrence for at least 20 years after their original diagnosis. (medicalnewstoday.com)
  • Oncotype DX breast cancer recurrence score) and outperformed prediction for both high- and low-risk groups. (nature.com)
  • The risk of disease recurrence or death was 28% lower in the group who received adjuvant atezolizumab plus bevacizumab compared to the group who had undergone active surveillance. (healthxchange.sg)
  • This retrospective study provides the possibility that propofol-based TIVA for breast cancer surgery can reduce the risk of recurrence during the initial 5 years after MRM. (ekja.org)
  • Among 919 patents with very-high-risk disease, 5-year recurrence free survival was 57% (95% CI = 52%-62%) in the everolimus group vs 51% (95% CI = 46%-56%) in the placebo group (HR = 0.79, 95% CI = 0.65-0.97, P = .022). (ascopost.com)
  • Even more importantly, we veal important information about the risk of recurrence. (lu.se)
  • Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival. (cancercentrum.se)
Racial Disparities1
Breast11
  • The findings of this investigation from Roswell Park Comprehensive Cancer Center showed that more aggressive tumor biology and significantly shorter survival were linked with low household income, even in breast cancer with a better prognosis. (medpagetoday.com)
  • 3 It is unclear, however, whether a similar linkage exists between low income and 21-gene recurrence score (RS) in estrogen receptor (ER)-positive breast cancer, which is much more common. (medpagetoday.com)
  • We have known that income level is associated with incidence of poor-prognosis triple-negative breast cancer, but our new study presents the first data to show that income level impacts survival even in breast cancer with a better prognosis. (medpagetoday.com)
  • We have known that income level is associated with incidence of poor-prognosis triple-negative breast cancer, but our new study presents the first data to show that income level impacts survival even in breast cancer with a better prognosis," says co-author Anurag K. Singh, MD, Professor of Oncology at Roswell Park Comprehensive Cancer Center. (medpagetoday.com)
  • However, she said her team and most U.S. surgeons thoroughly remove the breast tissue under the "envelope" of breast skin and nipple because they believe that recurrence rates will be lower using this technique. (news-medical.net)
  • Conceivably, however, breast tissue could remain at the nipple-areola complex or skin flaps, which might lead to a cancer recurrence, the study authors wrote. (news-medical.net)
  • What are the chances of breast cancer recurrence? (medicalnewstoday.com)
  • What are the real figures on breast cancer survival for women treated today? (google.com)
  • Breast cancer free survival (BCFS). (orlandohealth.com)
  • Survival from breast cancer has improved during the past dec- markerserumlevelshavebeenusedpreviously,e.g.,incalculating ades in the Western world. (lu.se)
  • R, Flisberg P, Hedlund L, Östlund I, Bergkvist L. Impact of general anaesthesia on breast cancer survival: a 5-year follow up of a pragmatic, randomised, controlled trial, the CAN-study, comparing propofol and sevoflurane. (cancercentrum.se)
Outcomes1
  • These results demonstrate that neoadjuvant T-VEC plus surgery improves cancer-related outcomes vs surgery alone, with acceptable safety,' the authors concluded, adding that the improvement in survival outcomes 'is likely the result of an induced systemic immunologic antitumor effect, as shown by elevated CD8+ density after T-VEC treatment. (medscape.com)
Nodal1
  • Conclusions: A third of men treated with sLND for PET-detected nodal recurrence of PCa died at long term, with PCa being the main cause of death. (uni-koeln.de)
Significantly decreased1
Prognostic1
Adjuvant1
Progression2
  • A single normal cell randomly acquires a series of mutations that allows it to proliferate and to be transformed into a cancer cell (i.e., founding clone), which initiates tumor progression and recurrence. (nature.com)
  • The study is limited by the definition and assessment of recurrence-free survival in the trial design, which does not account for disease progression during the neoadjuvant period. (medscape.com)
Ovarian2
  • What Are Ovarian Cancer Survival and Recurrence Rates for Black Women? (webmd.com)
  • Ovarian cancer survival rates are poorest for non-Hispanic white and Black women. (webmd.com)
Curative1
  • Patient summary: After curative treatment for localised kidney cancer, follow-up is necessary to detect any recurrence. (lu.se)
NSCLC1
Mastectomy2
Chemotherapy2
  • The aim of the present study was to investigate the effectiveness and safety of bladder intracavitary hyperthermic perfusion chemotherapy (BHPC) for prevention of NMIBC recurrence post-TUR. (spandidos-publications.com)
  • Bladder intracavitary hyperthermic perfusion chemotherapy (BHPC), the combination of local hyperthermia with chemotherapy, can significantly improve the effect of intracavity chemotherapy, and is reported to have an additive or supra-additive effect, preventing NMIBC recurrence post-TUR ( 13 - 16 , 18 - 20 ). (spandidos-publications.com)
Kaplan-Meier3
  • Case fatality and recurrence rates for 3 months, 1 year, and 5 years were estimated with Kaplan-Meier estimates. (nih.gov)
  • The Kaplan-Meier method was used to calculate the survival rates, and the log-rank test was used to compare groups. (researchsquare.com)
  • Survival was calculated from Kaplan-Meier curves, and toxicity was recorded using Common Terminology Criteria for Adverse Events version 3. (bmj.com)
Free survival2
Incidence1
  • Core activities of surveillance include measuring cancer incidence and characterizing each cancer with regard to histopathology, stage, and treatment in the context of survival. (cdc.gov)
Disease1
  • Using the RECUR database, we studied imaging intensity utilised in contemporary FU to evaluate its association with outcome after detection of disease recurrence. (lu.se)
Circulating1
Androgen deprivation therapy1
  • A significant survival benefit associated with the administration of androgen deprivation therapy after sLND suggests that sLND should be considered part of a multimodal approach rather than an exclusive treatment strategy. (uni-koeln.de)
20171
  • The study results suggest that use of more imaging during FU than that recommended in the 2017 EAU guidelines is unlikely to improve OS after recurrence. (lu.se)
Likelihood1
Treatment4
  • People who are diagnosed and begin treatment earlier have a higher chance of survival. (healthline.com)
  • We investigated time trends in ischemic stroke case-fatality and recurrence rates over 20-years stratified by etiological subtype according to the Trial of ORG 10172 in Acute Stroke Treatment classification within a population-based stroke register in Germany. (nih.gov)
  • Experts think that genes, other health conditions, and lack of access to treatment all affect survival rates. (webmd.com)
  • A landmark analysis suggests that limiting immune checkpoint inhibitor (ICI)-based treatment to 2 years confers the same survival benefit as extended treatment for advanced non-small cell lung cancer. (medpagetoday.com)
20231
Rates5
  • Sex-specific time trends for case-fatality and recurrence rates were estimated with Cox regression. (nih.gov)
  • No time trends in recurrence rates were observed. (nih.gov)
  • But these advances haven't equally boosted everyone's survival rates. (webmd.com)
  • These lower survival rates hold true no matter what stage of cancer they have. (webmd.com)
  • The Memorial Sloan Kettering Cancer Center, USA, based on the TNM system of staging based on the size of tumor, lymph nodes affected, and then metastases - has identified the survival rates of sarcoma of arms and legs. (news-medical.net)
Proliferation1
  • New somatic mutations arise and are selected if they confer a selective fitness advantage (e.g., proliferation, survival, etc.) to a founding clone in the context of a pre-existing genomic landscape (i.e., germline variants). (nature.com)
Invasion1
  • It has recently been demonstrated that propofol exerts anti-tumor properties through variable mechanisms, including suppression of the survival capability, dispersion, and invasion of cancer cells [ 7 ]. (ekja.org)
Treatments1
  • She reviews scientific literature (and debunks some commonly cited myths) by giving survival statistics corrected for current treatments and diagnostic profiles. (google.com)