Myeloproliferative DisordersJanus Kinase 2Polycythemia VeraPrimary MyelofibrosisThrombocythemia, EssentialMyelodysplastic-Myeloproliferative DiseasesThrombocytosisReceptors, ThrombopoietinLeukemia, Myelomonocytic, ChronicBone Marrow NeoplasmsLeukemia, Myelomonocytic, JuvenileSplenomegalyLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeFusion Proteins, bcr-ablHematopoiesis, ExtramedullaryMutationSTAT5 Transcription FactorBone MarrowHematopoietic Stem CellsLeukemia, Myeloid, AcuteMyelodysplastic SyndromesAnemia, RefractoryLeukocytosisGenes, ablOncogene Proteins, FusionProto-Oncogene Proteins c-cblPhiladelphia ChromosomeCell Transformation, NeoplasticMutation, MissenseJanus KinasesHematologic Neoplasmsfms-Like Tyrosine Kinase 3Bone Marrow TransplantationMegakaryocyte Progenitor CellsLeukemiaHematologyBone Marrow CellsGene Expression Regulation, LeukemicBlast CrisisMyelopoiesisCell ProliferationClonal EvolutionSignal TransductionMegakaryocytesLeukemia, MyeloidBenzamidesProto-Oncogene ProteinsMyeloid Progenitor CellsAmino Acid SubstitutionGene Knock-In TechniquesAnemia, SideroblasticProtein Kinase InhibitorsDNA Mutational AnalysisMyeloid CellsMice, Inbred C57BLLeukemia, Neutrophilic, ChronicHematopoiesisDisease Models, AnimalPyrimidinesRetroviridaeTranslocation, GeneticMegakaryocyte-Erythroid Progenitor CellsPiperazinesBone Marrow DiseasesPhenotypeReceptors, ErythropoietinPoint MutationProtein-Tyrosine KinasesSarcoma Viruses, MurineMice, TransgenicHypereosinophilic SyndromeTransduction, GeneticReceptor, Fibroblast Growth Factor, Type 1Moloney murine sarcoma virusExonsNeoplasmsDisease ProgressionMice, KnockoutPyrazolesCell Line, TumorGranulocytesLeukemia, Megakaryoblastic, AcuteThrombopoietinCell LineMice, Inbred BALB CPrognosisThrombosisPolycythemiaDNA-Binding Proteins