Selenium, of course, is an antioxidant that works with vitamin E to protect cells from the damaging effects of free radicals. (radiationdangers.com)
Dietary and supplemental selenium is required for the optimal functioning of the selenium-dependent enzymes known as selenoproteins. (pharmanord.com)
It is estimated that the population suffering from micronutrient malnutrition, between 60-80% of the population are deficient in iron (Fe), over 30% are deficient in zinc (Zn), 30% are deficient in iodine (I) and about 15% are deficient in selenium. (uach.mx)
Arsenic metabolism is affected by tissue and blood levels of zinc, selenium, arginine, choline, methionine, taurine, and quaniacetic acid, all of which affect methyl-group metabolism and polyamine synthesis which is the site of arsenic function in human physiology. (mighty-90.com)
Selenium improves immunologic function by increasing the activity of interleukin-2 (IL-2) and promoting the normal growth and development of T helper cells. (mymmunity.com)
Selenium, zinc, and copper concentrations in the blood and milk of lactating women. (therapeuticresearch.com)
Folate1
Fazili Zand Pfeiffer CM. Accounting for an isobaric interference allows correct determination of folate vitamers in serum by isotope dilution-liquid chromatography-tandem mass spectrometry external icon . (cdc.gov)
Stable2
Pawlosky RJ, Flanagan VP, Pfeiffer CM. Determination of 5-methyltetrahydrofolic acid in human serum by stable-isotope dilution high-performance liquid chromatography-mass spectrometry external icon . (cdc.gov)
Plutonium is the heaviest primordial element by virtue of its most stable isotope , plutonium-244 , whose half-life of about 80 million years is just long enough for the element to be found in trace quantities in nature. (infogalactic.com)
Copper9
1990. A review on biochemical roles, toxicity and interactions of zinc, copper and iron: IV. (cdc.gov)
Zinc and copper modulate differentially the P2X receptor. (cdc.gov)
Radial and median nerve conduction velocities in workers exposed to lead, copper, and zinc: A follow-up study for 2 years. (cdc.gov)
1992. Auditory event-related potential (P300) in relation to peripheral nerve conduction in workers exposed to lead, zinc, and copper: Effects of lead on cognitive function and central nervous system. (cdc.gov)
1994. Inhibition of Na+-glucose cotransport in kidney cortical cells by cadmium and copper: Protection by zinc. (cdc.gov)
1995. Copper and zinc metabolism in health and disease: Speciation and interactions. (cdc.gov)
1992. Use of zinc acetate to treat copper toxicosis in dogs. (cdc.gov)
Copper's essentiality was first discovered in 1928, when it was demonstrated that rats fed a copper-deficient milk diet were unable to produce sufficient red blood cells. (wikipedia.org)
Since copper availability in the body is hindered by an excess of iron and zinc intake, pregnant women prescribed iron supplements to treat anemia or zinc supplements to treat colds should consult physicians to be sure that the prenatal supplements they may be taking also have nutritionally-significant amounts of copper. (wikipedia.org)
Plutonium1
Plutonium isotopes are expensive and inconvenient to separate, so particular isotopes are usually manufactured in specialized reactors. (everipedia.org)
Zinc metabolism in patients treated with captopril versus enalapril. (therapeuticresearch.com)
Radioactive2
Am-Americum are radioactive isotopes and have a half-life of 7,950 years. (mighty-90.com)
At-Atatine is a radioactive isotope with an extremely short half-life of 7.2 to 8 hours. (mighty-90.com)
Vitro4
1976. The in vitro effect of zinc on the inhibition of human *-aminolevulinic acid dehydratase by lead. (cdc.gov)
A preliminary in vitro experiment was accomplished, using a 169 Er-PSMA-617, to show the potential of 169 Er to reduce tumor cell viability. (frontiersin.org)
Further, GABA-deficient islets did not show appropriate glucagon inhibition in response to increasing glucose concentrations in vitro 22 , suggesting that GABA is directly involved in the suppression of glucagon secretion in pancreatic alpha cells. (nature.com)
Here we develop and apply the principles of their evolution from systems principally for evaluating mechanism dosimetry in vitro and outline an approach for simulation of of toxicity to high-throughput systems for rapid and cost-effective nanoparticle particokinetics in cell culture systems. (cdc.gov)
19982
1998. Zinc acetate treatment in Wilson's disease. (cdc.gov)
1998. The effect of zinc supplementation on the effects of lead on the rat testis. (cdc.gov)
Serum3
Fazili Z, Pfeiffer CM. Measurement of folates in serum and conventionally prepared whole blood lysates: application of an automated 96-well plate isotope-dilution tandem MS method external icon . (cdc.gov)
McCoy LF, Scholl PF, Schleicher RL, Groopman JD, Powers CD, Pfeiffer CM. Analysis of aflatoxin B1-lysine adduct in serum using isotope-dilution liquid chromatography/tandem mass spectrometry external icon . (cdc.gov)
Mineva EM, Schleicher RL, Chaudhary-Webb, M, May KL, Botelho JC, Vesper HW, Pfeiffer CM. A candidate reference measurement procedure for quantifying serum concentrations of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 using isotope-dilution liquid chromatography-tandem mass spectrometry external icon . (cdc.gov)
Neutron2
In this study, an electromagnetic isotope separation technique was applied after neutron irradiation to boost the specific activity by separating 169 Er from 168 Er targets. (frontiersin.org)
Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY. (lookformedical.com)
Concentrations1
Modulation of tissue trace metal concentrations in weanling rats fed different levels of zinc and exposed to oral lead and cadmium. (cdc.gov)
Aluminum1
Antagonistic effects of zinc and aluminum on lead inhibition of *-aminolevulinic acid dehydratase. (cdc.gov)
Acid3
Gamma aminobutyric acid(GABA) is synthesized by glutamate decarboxylase(GAD) in β-cells. (nature.com)
Multiple immunological abnormalities have been reported in T1D patients including autoantibody production against the insulin molecule, the 65 kD isoform of glutamic acid decarboxylase (GAD65), various islet antigens, and the zinc transporter 8 (ZnT8) as well as decreased regulatory T cell (Treg) capacity to suppress T-cell mediated destruction of the islets of Langerhans 3 . (nature.com)
Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). (ncats.io)
Mass1
Once hyperglycemia appears, more than 70% of islet beta cell mass has been eradicated 4 . (nature.com)
Iron5
Most of the iron in the body is found in red blood cells and muscle cells. (webmd.com)
Iron helps red blood cells carry oxygen from the lungs to cells all over the body. (webmd.com)
Taking iron by mouth or by IV along with other medications such as epoetin alfa can help build red blood cells and prevent or treat anemia in people with certain chronic diseases. (webmd.com)
Low levels of healthy red blood cells (anemia) due to iron deficiency . (webmd.com)
Deficiencies of iron (Fe) and zinc (Zn) are a critical public health problem worldwide, with negative impact on health, lifespan and productivity. (uach.mx)
Human2
Effects of butyrate and propionate on the adhesion, growth, cell cycle kinetics, and protein synthesis of cultured human gingival fibroblasts. (ncats.io)
SCFA increase intestinal Na absorption by induction of NHE3 in rat colon and human intestinal C2/bbe cells. (ncats.io)
Effects1
1985. Effects of marginal zinc deficiency on subclinical lead toxicity in the rat neonate. (cdc.gov)
Patients2
As for GAD65 antigen (GAD-alum) treatment per se in new onset T1D, an initial 2008 report of 70 patients was auspicious insofar as residual beta-cell function over 30 months was somewhat preserved. (nature.com)
Prognostic significance of MATR3 in stage I and II non-small cell lung cancer patients. (nih.gov)
Levels1
Low levels of red blood cells in people with a long-term illness ( anemia of chronic disease). (webmd.com)
Development1
2013). Microglial cell activation plays a major role in the development of this nociceptive sensitization (Wieseler-Frank et al. (niepokorny.org)
Function1
Given the low GABA dose for this pediatric trial, future investigations using higher-dose or long-acting GABA formulations, either alone or with GAD-alum, could be considered, although GABA alone or in combination with GAD-alum did nor preserve beta-cell function in this trial. (nature.com)
Found1
Regarding Type 1 diabetes(T1D), animal/islet-cell studies found that GABA promotes insulin secretion, inhibits α-cell glucagon and dampens immune inflammation, while GAD immunization may also preserve β-cells. (nature.com)
Quality1
B cells are therefore particularly dependent on 'quality control' mechanisms to oversee antibody production. (cipsm.de)
Essential1
Calcium is very essential in muscle contraction, oocyte activation, building strong bones and teeth, blood clotting, nerve impulse, transmission, regulating heart beat and fluid balance within cells. (researchgate.net)
Role1
DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. (cipsm.de)
Strategies1
B cells use unconventional strategies for the production of a seemingly unlimited number of antibodies from a very limited amount of DNA. (cipsm.de)
Live1
Preexisting antivector immunity can severely compromise the ability of Salmonella enterica serovar Typhimurium live vaccines to induce protective CD8 T-cell frequencies after type III secretion system-mediated heterologous protein translocation in orally immunized mice. (cipsm.de)
Normal1
Hiramatsu T, Imoto M, Koyano T, Umezawa K. Induction of normal phenotypes in ras-transformed cells by damnacanthal from Morinda citrifolia. (therapeuticresearch.com)