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  • oxygen
  • As the first and initiating oxygen free radical in the ROS chain, superoxide (O 2 โˆ’ ) consumption of NO is one of the most important mechanisms of endothelial dysfunction. (ahajournals.org)
  • Healthcare providers give superoxide dismutase as a shot for certain bladder infections (interstitial cystitis), osteoarthritis, rheumatoid arthritis (RA), and lung damage that sometimes develops in premature infants who have been given oxygen to help them survive. (webmd.com)
  • kidney
  • Superoxide dismutase is also given as a shot for improving tolerance to radiation therapy, improving rejection rates in kidney transplantation, and minimizing heart damage caused by heart attacks . (webmd.com)
  • activity
  • 7 The normal activity of CuZnSOD is necessary to limit increases in superoxide, allowing release of NO from endothelium and normal endothelium-dependent relaxation. (ahajournals.org)
  • Does someone have an assay or references on how to measure superoxide dismutase activity in a flowcytometer? (bio.net)
  • lung
  • Superoxide dismutase 3 is associated in reduced lung functions and susceptibility to chronic obstructive pulmonary disease as well as implicated as contributing factor to altered ventilation efficiency. (biology-online.org)
  • known
  • Though there are no reports of people getting sick after using superoxide dismutase products taken from animals, it's best to avoid products from animal sources until more is known. (webmd.com)
  • Not enough is known about the use of superoxide dismutase during pregnancy and breast -feeding. (webmd.com)
  • This review summarizes what is known about superoxide dismutases in pancreatic cancer and the most current treatment strategies to be advanced from this knowledge. (mdpi.com)
  • shown
  • A controlled study has shown that topical application of superoxide dismutase (SOD) fused with the TAT peptide (TAT-SOD), to various acupoints along the meridian lines used in acupuncture to treat obesity, leads to significant weight loss [ 15 ], monitoring the effects of acupoint antioxidant intervention by measuring electrical potential difference along the meridian [ 16 ]. (hindawi.com)
  • specific
  • A series of case reports suggest that a specific eye solution of superoxide dismutase might help reduce ulcer size and improve healing when applied to the eye for at least 2 weeks. (webmd.com)
  • Thus
  • The superoxide anion (O 2 -) is negatively charged and thus cannot be diffused through membranes and oxidizes [4Fe-4S] 2+ in to [3Fe-S] 1+ by releasing iron (Fe 2+ ). (omicsonline.org)