• This technique involved the use of alcohol to separate the corneal epithelium from the stroma to create an epithelial sheet that could be repositioned over the ablated stroma. (medscape.com)
  • In corneal ulceration there is a loss of epithelium plus varying amounts of stroma. (vin.com)
  • Superficial lesions are more painful than deep because the sensory nerve endings are within the epithelium. (vin.com)
  • in a corneal transplant technique known as deep anterior lamellar keratoplasty (DALK) the donated corneal tissue replaces the corneal stroma and epithelium only. (merckmanuals.com)
  • Salzmann"s corneal degeneration is characterized by the presence of white-to-gray or light blue nodules that elevate the epithelium in the superficial corneal stroma. (reviewofoptometry.com)
  • It is composed of three layers: the outer epithelium, the stroma and the inner endothelium. (eye-vet.co.uk)
  • But to confirm the diagnosis, we use an orange dye called fluorescein, which when put in the eye sticks to the stroma (the layer underneath the epithelium) staining it green. (eye-vet.co.uk)
  • These are superficial ulcers which fail to heal because although the epithelium grows across the stroma, it fails to adhere to it. (eye-vet.co.uk)
  • The superficial stroma underlying the luminal epithelium is formed by four or five layers of round shaped and compactly arranged endometrial fibroblasts. (jri.ir)
  • The cornea is made of 3 different layers: an outer superficial layer (epithelium), a middle layer (stroma) and an inner thin layer (endothelium). (waterlooeye.ca)
  • Our study examined the effect of a selective Rho kinase inhibitor, Y-27632, on corneal wound healing and potential stromal scarring after superficial keratectomy. (molvis.org)
  • Only the corneal endothelium needs to be transplanted in diseases where the corneal stroma is clear, has a smooth stromal surface with a regular curvature, and only the corneal endothelium is not functioning well (eg, Fuchs dystrophy, bullous keratopathy resulting from cataract surgery). (merckmanuals.com)
  • More active intervention with a bandage contact lens, epithelial debridement, 1 superficial keratectomy with a diamond burr, 2 anterior stromal puncture, 3 and Nd:YAG laser 4 have been used with varying success. (bmj.com)
  • C, Stromal bed after trephination of the posterior stroma and endothelium with flap reflected and trephination opening (arrows). (jamanetwork.com)
  • We also class them according to their depth, as superficial or deep (anterior, mid or deep stromal). (eye-vet.co.uk)
  • It is more useful in keratoconus and superficial stromal scars with an adequate corneal thickness. (waterlooeye.ca)
  • Y-27632 eye drops (or vehicle only) were administered to eyes after a superficial keratectomy, and the tissue was examined by immunohistochemistry for α-SMA, collagen types I, II, and III, and keratan sulfate. (molvis.org)
  • Y-27632 inhibits keratocyte-to-myofibroblast transition, and its topical application after a superficial lamellar keratectomy elicits an altered wound healing response, with evidence of an embryonic-type deposition of collagen fibrils. (molvis.org)
  • In phototherapeutic keratectomy (PTK), an excimer laser is used to treat a variety of corneal disorders such as surface irregularity, epithelial instability, and superficial opacity. (crstodayeurope.com)
  • As such a superficial keratectomy (under general anaesthetic) may be discussed. (uk.net)
  • Removal of the nodules is often accomplished by peeling them from the underlying stroma after a plane has developed from scraping around the edge of the lesion, or by Excimer laser phototherapeutic keratectomy. (reviewofoptometry.com)
  • Light microscopy shows irregular thickening and thinning of the epithelial layer, which offset the ridges and furrows in the underlying stroma and the focal absences of the epithelial basement membrane. (aao.org)
  • The hallmark microscopic feature of this disease is an extensive and often marked intracellular edema of the superficial epithelial cells, predominantly within the spinous layer. (intelligentdental.com)
  • Leukoedema is another developmental phenomenon with childhood onset and abundant superficial epithelial cells with edema. (intelligentdental.com)
  • Frictional keratosis, especially chronic cheek bite keratosis, may also present with intracellular edema of superficial epithelial cells, but there is usually extensive surface keratosis, vertical infolding is absent, and only occasional nuclei are pyknotic. (intelligentdental.com)
  • A Superficial Chronic Corneal Epithelial Defect (SCCED) or indolent ulcer is an ulcer which fails to heal in the expected time. (uk.net)
  • Microscopic evaluation showed anastomosing cords, trabeculae, nests, and tubules of epithelial-like cells found in a fibroblastic stroma (Figure 1 ). (turkjpath.org)
  • Anastomosing cords, trabeculae, nests and tubules of epithelial-like cells were lying in a fibroblastic stroma. (turkjpath.org)
  • For example, intraepithelial cysts, deposits in basal epithelial cells, subbasal microfolds, reduplicated basement membrane, damaged subbasal nerves, and altered morphology of anterior stroma can be seen in MD without erosions. (entokey.com)
  • In estrous cycle and on day 4 of pregnancy, the rat endometrial stroma has two morphologically distinct compartments, denominated supepithelium and deep stroma. (jri.ir)
  • On days 5 and 6 of pregnancy, rat endometrial stroma has five compartments. (jri.ir)
  • Penetrating keratoplasty (PK), Descemet's stripping endothelial keratoplasty (DSEK/ DSAEK), Descemet's membrane endothelial keratoplasty (DMEK), deep anterior lamellar keratoplasty (DALK), superficial anterior lamellar keratoplasty (SALK) and artificial cornea transplant all involve removing the damaged or diseased cornea and replacing it with an artificial one. (mantracare.in)
  • Superficial ulcers may/may not be seen with the naked eye, but the use of the biomicroscope or the +12d lens of the direct ophthalmoscope is helpful and the uptake of the fluorescein by the denuded stroma is easily noted. (vin.com)
  • Uncomplicated superficial ulcers should heal rapidly within a few days at most if managed medically, and there is no need for surgical intervention. (vin.com)
  • Generally, corneal ulcers are described as superficial or deep. (uk.net)
  • Ulcers that only involve the outer skin are called superficial ulcers or erosions. (uk.net)
  • Most superficial ulcers heal rapidly as the cells of the surrounding outer 'skin' slide and grow into the defect. (uk.net)
  • Most superficial ulcers will have healed within a week. (uk.net)
  • While superficial, uncomplicated ulcers can heal within a week on antibiotic eye drops and lubrication, some ulcers can become deeper. (eye-vet.co.uk)
  • Anterior keratoplasty (ALK) replaces the superficial anterior section of the cornea while DALK replaces the entire stroma, or mid-section of the cornea. (linkocare.com)
  • All patients were treated with a superficial therapeutic ablation profile with a Visx, Nidek, or Summit 193 nm excimer laser. (bmj.com)
  • In excimer laser procedures done on the superficial corneal stroma, haze formation is possible. (msdmanuals.com)
  • MO/MA were present on both sides of the pelvic peritoneum in EOC patients, with infiltration of the subjacent stroma and mesothelium. (biomedcentral.com)
  • Its surface mesothelium and submesothelial stroma and structure pose no substantial barriers to inflammatory modulatory cytokines, chemokines and other molecules produced by the tumor or its metastasis, at least to a depth of approximately 1 mm [ 2 ]. (biomedcentral.com)
  • The ovarian stroma showed extensive oedema. (who.int)
  • The ovarian stroma cancer, was 27.56 U/mL, beta-human showed extensive oedema. (who.int)
  • It is a faint opacity which results due to superficial scars involving Bowman's layer and superficial stroma. (mdwiki.org)
  • There was a suspicion of superficial focal myometrial invasion. (turkjpath.org)
  • Currently there are two principal techniques: either sculpting the refractive shape onto the superficial corneal stroma (surface technique) or cutting a flap through the cornea with a femtosecond laser to allow excimer sculpting deeper in the stroma (flap-based technique). (gponline.com)
  • To begin the procedure, LASIK uses a tiny blade called a microkeratome to create a small, superficial flap in the cornea. (inlandeye.com)
  • The flap is raised to access the underlying cornea, known as the stroma. (inlandeye.com)
  • For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. (bvsalud.org)
  • The ascomata is solitary or aggregated, superficial on or immersed in the stroma. (wikipedia.org)
  • However, situations often arise where clinical appearance and impression from a superficial histopathologic examination are misleading and may direct to a completely erroneous diagnosis. (medscape.com)
  • With time, the opacities may extend to the limbus and deeper stroma (Fig 7-6C, D). (aao.org)
  • In more advanced stages of the disease, the opacities can extend to the limbus and deeper stroma (2). (uiowa.edu)
  • Confluent, irregular, and coarse geographic opacities with varying densities develop at the level of the Bowman layer and superficial stroma, mostly centrally (Fig 7-6B). (aao.org)
  • Irregular, grey-white, geographic-like opacities are located in the Bowman layer and anterior stroma. (uiowa.edu)
  • It is characterized by lattice lines which are linear, radially oriented, branching refractile opacities described as 'glass like' located in the anterior stroma (See Figure 2A and 2B). (uiowa.edu)
  • Recurrent corneal erosion syndrome (RCES) is a relatively common condition and may be classified as either dystrophic (dystrophic-RCES) where it occurs associated with an anterior corneal dystrophy, or non-dystrophic (ndRCES) where it occurs following superficial corneal trauma (post-traumatic RCES) or unrelated to any pre-existing corneal disease or past history of trauma (idiopathic RCES). (bmj.com)
  • The dystrophies typically have an autosomal dominant inheritance and involve Bowman layer and stroma (3). (uiowa.edu)
  • En bloc' removal of the tumor was accomplished, leaving the adjacent conchal cartilage attached to the tumor and using the CADISS technique to preserve the deep perichondrium. (mdpi.com)
  • A progression of superficial ulceration through deep ulceration to descemetocele formation and corneal rupture with uveitis and possible endophthalmitis can occur. (vin.com)
  • 4. Vascularization--usually superficial, but it can be deep too. (vin.com)
  • Historically, cheilitis glandularis has been subclassified into 3 types: simple, superficial suppurative, and deep suppurative. (medscape.com)
  • The deep suppurative type has also been variously referred to as myxadenitis labialis or cheilitis apostematosa, and the superficial suppurative type has been termed Baelz disease. (medscape.com)
  • A few scattered breast lobules are seen deep in the skin and subcutis, embedded within fibrous stroma. (basicmedicalkey.com)
  • The deep stroma, situated between the superficial stroma and the myometrium, is composed of elongated and loosely arranged endometrial fibroblasts. (jri.ir)
  • The first two compartments (supepithelium and deep stroma) are similar to those of the estrous cycle. (jri.ir)
  • This protein acts as an adhesion protein and is present in normal stroma. (uiowa.edu)
  • Being a small protein roughly the size of albumin, it has the capability to diffuse through the corneal stroma. (uiowa.edu)
  • Many believe these subtypes represent a continuum of disease, where the simple type, if not treated, could become secondarily infected and progress to become the superficial or eventually, the deeply suppurative type. (medscape.com)
  • Scattered chronic inflammatory cells are usually found within the subepithelial stroma. (intelligentdental.com)
  • Smokeless tobacco keratosis may demonstrate pronounced intracellular edema of superficial cells, sometimes extending to the parabasal region. (intelligentdental.com)
  • Light scattering at 1 month was more defined in the superficial stroma and gradually reduced to zero at 240μm depth. (ophthalmologytimes.com)
  • They generally have a sexual morph that has a byssoid (wispy, cottony or teased wool appearance) stromata which is well-developed or scant and white to brown or dark-brown. (wikipedia.org)
  • Stroma erumpent, brown and pseudoparenchymatous. (dothideomycetes.org)
  • by the end of the first week, the superficial implantation of the blastocyst is complete. (medscape.com)