Supercritical dissolution processes supercritical fluids. Medical search. Frequent questions

This paper focuses on the synthesis and characterization of Pt/ceria WGS catalysts prepared using supercritical fluid deposition (SCFD), a technique by which organometallic precursors are adsorbed from a supercritical fluid solvent on to a support. (confex.com)
With developing new technologies such as non-aqueous bitumen extraction, the need to track solvent interactions with oil sands components throughout the extraction process and to identify. (ualberta.ca)
Additionally, supercritical "anti-solvent" applications are possible. (analytix.co.uk)
The solvent itself is highly volatile, allowing for its evaporation after the separation process. (baypat.de)
In this process, the FSC is used as the solvent. (top-supercritical.com)
This fluid, according to the temperature and the pressure, can reach significant densities that boosts the solvation phenomenon by decreasing the intermolecular lenghs and consequently the interactions that exist between the solvent molecules and the chemical specie inserted during the dissolution of a compound in a solvent. (top-supercritical.com)
In the RESS process, one or many substance(s) is (are) dissolved in the SCF, employed here as the solvent, at determined temperature and pressure conditions so that the solute/solvent mix be an homogeneous solution. (top-supercritical.com)
In these processes, the FSC is used as an anti-solvent. (top-supercritical.com)
In the continuous anti-solvent process, the solution and the anti-solvent bring together at the expansion nozzle and are injected cocurrent. (top-supercritical.com)
A washing or extraction with pur CO2 step is recommended at the process end to eliminate the last solvent traces that could be in the cristallized particules. (top-supercritical.com)
give similar crystallinity and dissolution results compared to those produced with supercritical fluids as solvent. (bvsalud.org)
Solvent-based purification involves the use of a selective solvent dissolution process to eliminate impurities from postindustrial and postconsumer plastics. (techsciresearch.com)
In the dissolution precipitation process, the cleaned plastics are subjected to a solvent to dissolve dyes, pigments, and other such impurities. (techsciresearch.com)
Through techniques like supercritical fluid precipitation and anti-solvent crystallization, gas-solvent systems can be employed to control particle size, shape, and morphology. (gasesgrit.com)
From enhanced reactions and catalysis to supercritical fluid extraction, particle engineering, and green solvent systems, this versatile technique enables scientists to overcome challenges and develop innovative solutions. (gasesgrit.com)
At near critical temperature, SCFs are highly compressible allowing moderate changes in pressure to greatly alter the density and mass transport characteristics of a fluid that determines its solvent power. (ijpsr.com)
Measuring solubility of crystal in various solvent is a key factor in compound characterizing during the whole discovery and development process where it allows engineers to design and optimize crystallization process. (azpdf.org)
The analyses has shown that co-solvent is an effective method in increasing the dissolution rate of a sparingly soluble chemical and temperature plays important role in increasing the solubility. (azpdf.org)
It is an unwanted byproduct in many large scale oxidation processes, for example, in the production of acrylic acid -over 5 million tons/year-.It is a versatile industrial material, used, for example, as an inert gas in welding and fire extinguishers, as a pressurizing gas in air guns and oil recovery, as a chemical feedstock and as a supercritical fluid solvent in decaffeination of coffee and supercritical drying. (openfoodfacts.org)

The SFT Phase Monitor II is a powerful analytical tool for determining the solubility parameters of compounds and mixtures in subcritical and supercritical fluids. (analytix.co.uk)

Measurement and modeling of acridine solubility in supercritical carbon dioxide. (ac.ir)

Experiments can be performed in liquid or supercritical carbon dioxide and in other liquefied gases. (analytix.co.uk)
The multi-stage process originates with a gas phase mixture of MoF 6 and UF 6 which is fed into a liquid or supercritical fluid phase to dissolve both metal fluorides. (baypat.de)

Unlike conventional hydrothermal systems that use water or brine, CPG utilizes pure supercritical CO2 (scCO2) or water-bearing scCO2 as the subsurface working fluid. (ethz.ch)
While the dissolution of CO2 bubbles in reservoir brine is a crucial mechanism towards safe CO2 storage, it is a process that occurs at the pore-scale and is not yet fully understood. (researchgate.net)
Actual rock cores representing different areas of carbonate oil field saturated with actual fluids of filtrated brine and asphaltenic crude oil were used to evaluate the interaction between supercritical (SC)-CO 2 , carbonate rock, and its contained fluid. (uaeu.ac.ae)
Almehaideb, Reyadh A. / Investigation of supercritical carbon dioxide, aspheltenic crude oil, and formation brine interactions in carbonate formations . (uaeu.ac.ae)
Indeed - compared to the usual use of a supercritical phase - this project using dissolved CO2 allows lower brine displacement risks, lower CO2 escape risks, and the potential for more rapid mineralization. (gouv.fr)
The results showed that most significant diagenetic changes in shale rocks after flooding with CO -brine, reflect in the effluent fluid with predominantly calcium based minerals dissolving and precipitating under experimental conditions. (lsu.edu)
4) investigation of the phase behavior of H 2 S initially available and dissolved in brine during CO 2 sequestration process. (scipedia.com)

Our results suggest that the density increase of resident species causes significant enhancement in CO 2 dissolution, although no significant porosity and permeability alterations are observed. (nature.com)
In addition, precipitation and dissolution of minerals may lead to an alteration in porosity and permeability of the host formation. (nature.com)
Ennis-King and Paterson 20 investigated analytical and numerical methods and observed that the overall dissolution rate depends on the balance between the effects of permeability alterations and the consumption of dissolved CO 2 . (nature.com)
Asphaltene content of the produced crude oil, water and mineralogical rock analyses, and scanning electron microscopic (SEM) photos of rock pores were performed to evaluate the effect of supercritical (SC)-CO 2 flood on the permeability and mineralogical variation characteristics of the limestone cores. (uaeu.ac.ae)
Results indicated that calcite dissolution and/or precipitation is the major reason for permeability improvement and/or impairment. (uaeu.ac.ae)
It is because of precipitation and dissolution that cause permeability alternations. (ac.ir)
Dan Zhou § , Ye Zhang , Guillaume Gianni, Peter Lichtner, Irina Engelhardt (2018) Numerical modeling of stream-aquifer interaction: quantifying the impact of transient sreambed permeability and aquifer heterogeneity, Hydrological Processes , in press, https://doi.org/10.1002/hyp.13169. (uwyo.edu)
Surfactants are very useful as absorption enhancers and enhance both dissolution rate as well as permeability of drug. (ijpsr.com)

Our results indicate that fluid-mineral interactions involving CO2-rich supercritical fluids are less severe than those caused by aqueous solutions. (ethz.ch)
The CO2-DISSOLVED project main goals were to assess the technical-economic feasibility of a new industrial CCS concept integrating geothermal energy recovery, aqueous dissolution of CO2 and injection via a doublet system, and an innovative post-combustion CO2 capture technology. (gouv.fr)
It also has the potential to enhance subsequent carbon dioxide dissolution from the supercritical phase into the aqueous phase. (vt.edu)
This chemical shows low aqueous solubility and dissolution rate and this has become the main concern in the industry that require dissolution of this chemical. (azpdf.org)
It considers all types of reactions (aqueous complexation, adsorption-desorption, precipitationdissolution, ion-exchange, hydrolysis, and abiotic and biotic-mediated redox) as both fast/equilibrium and/or slow/kinetic processes, using a consistent definition of fast/equilibrium reaction rates. (benthamscience.com)

Development and Validation of Retention Models in Supercritical Fluid Chromatography for Impregnation Process Design. (tuhh.de)

Since the emergence of Soluplus® (SOL) as a commercial graft copolymer, multiple publications have been issued on its promising potential as a solubilizing excipient that could promote the dissolution rate and bioavailability of several poorly water-soluble drugs. (pharmaexcipients.com)

Supercritical fluids (SCFs) offer unique advantages for interfacial deposition processes. (confex.com)
The thesis aims to fabricate hybrid (organic-inorganic) complex materials as drug carriers using supercritical fluids (SCFs) with adequate properties for their application in biomedicine. (uab.cat)

The composition of the oil shale may lend added value to the extraction process through the recovery of by-products, including ammonia, sulfur, aromatic compounds, pitch, asphalt, and waxes. (wikipedia.org)
Additionally, the effect of co-solvents on the solubility of compounds in supercritical carbon dioxide can be investigated with this instrument. (analytix.co.uk)
It allows the end user to view dissolution, precipitation, and crystallization of compounds over a wide range of pressures and temperatures. (analytix.co.uk)
This data is useful for determining processing conditions for selective extraction, reaction, and/or fractionation of compounds of interest. (analytix.co.uk)
Through this study, we show new possibilities of using CO2 for insoluble compounds in this fluid. (bvsalud.org)

Natural sources include volcanoes, hot springs and geysers, and it is freed from carbonate rocks by dissolution in water and acids. (openfoodfacts.org)

engineering with supercritical fluids in pharmaceutics. (asiapharmaceutics.info)

Supercritical CO2 fluid extraction is based on the selectivity of supercritical CO2 fluid to the solubility of solutes to achieve the separation of material components. (angleroller.com)

Interfacial properties have a regulatory role in processes which involve the coexistence of different phases. (ualberta.ca)
Hypothesis: Understanding interfacial mass transfer during dissolution of gas in a liquid is vital for optimising large-scale carbon capture and storage operations. (researchgate.net)

More sophisticated applications include the determination of processing conditions for impregnating materials into swollen polymers and surface deposition experiments. (analytix.co.uk)
Modeling and investigating effects of CO 2 injection into carbonate formations during WAG processes, investigating parameters related to chemical reactions between reservoir rock and injecting fluid and also better understanding of the process theory for future experiments are the most important goals of this paper. (ac.ir)
This project entails laboratory experiments in which researchers will control and study the process of miscible density-driven convection. (vt.edu)

By using high pressure reactor, DSC, HPLC and in vitro dissolution tests, the crystallinity and dissolution profiles of MS with different pore size (6.6 nm, 25.0 nm and 2.5 nm) impregnated with fenofibrate (FF) under Sc-CO2 were compared to select the most appropriate carrier. (bvsalud.org)

The changes in phase behavior as a function of temperature, pressure, and sample concentration can be investigated rapidly, saving time in the scale-up of supercritical fluid processes. (analytix.co.uk)
The supercritical CO2 fluid extraction process can be divided into three types of processes: isobaric changes in temperature, isothermal changes in pressure, and isobaric with isothermal. (angleroller.com)
In addition to the standard adjustments of the milling process (i.e., speed, screen size, design of rotor, load), special techniques of milling may be useful including special atmosphere, temperature control, sonocrystallization, supercritical fluid process. (asiapharmaceutics.info)
Supercritical fluids ( e.g. carbon dioxide) are the fluids whose temperature and pressure are greater than their critical temperature (Tc) and critical pressure (Tp), allowing it to assume properties of both liquid and gas. (ijpsr.com)
It iteratively solves the Richards equation for fluid flow, the thermal transport equation for temperature fields, and reactive biogeochemical transport equations for concentration distributions. (benthamscience.com)

Furthermore, we analyzed fluid effluents using inductively coupled plasma optical emission spectroscopy (ICP-OES) to gain insights into ion transport processes associated with dissolution reactions. (ethz.ch)
The Phase Monitor II is useful for other supercritical fluid processing operations, such as crystallizations and reactions. (analytix.co.uk)
For example, the Phase Monitor can be utilized to determine the solubility of reactants and products so that the conditions for running supercritical reactions can be determined. (analytix.co.uk)
Simulation results suggested that influx-induced mineral dissolution/precipitation reactions within clay-based sedimentary rocks can continuously close micro-fracture networks, though injection pressure and effective-stress transformation first rapidly expand the fractures. (lsu.edu)
The dissolution of gases, such as hydrogen chloride (HCl) or Ammonia (NH 3 ), in organic solvents can significantly impact chemical reactions in the pharmaceutical industry. (gasesgrit.com)
This chapter presents the development of the latest version of HYDROGEOCHEM a multidimensional numerical model of coupled fluid flow, thermal transport, hydrologic transport, and biogeochemical kinetic/equilibrium reactions in saturated/unsaturated media. (benthamscience.com)

Supercritical water, supercritical carbon dioxide and other selected organic solvents in their supercritical state were studied. (ualberta.ca)

Mingkan Zhang § , Ye Zhang , Peter Lichtner (2017) Evaluating model complexity in simulating supercritical CO2 dissolution, leakage, footprint, and reservoir pressure for three-dimensional hierarchical aquifer, International Journal of Greenhouse Gas Control , Vol.64, p. 284-299, http://dx.doi.org/10.1016/j.ijggc.2017.07.022. (uwyo.edu)

Over the past decade, laboratory based X-ray computed micro-tomography (micro-CT) has given unique insights in the internal structure of complex reservoir rocks, improving the understanding of pore scale processes and providing crucial information for pore scale modelling. (researchgate.net)
Especially in-situ imaging using X-ray optimized Hassler type cells has enabled the direct visualization of fluid distributions at the pore scale under reservoir conditions. (researchgate.net)
This time restriction is often a bottleneck for imaging dynamic in-situ processes, thus limiting the applicability to relatively slow pore scale processes occurring in the order of hours to days, or to end points in drainage-imbibition cycles. (researchgate.net)
In this work we show two different applications: CO2 dissolution in the pore-scale and single-phase species transport in fractured porous media. (researchgate.net)

Considerable amounts of arsenic in mud irrespective of fluid composition suggested possible release through biogeochemical processes in the subsurface environment. (edu.au)
We present the ability to generate microscale and multiscale-porous media using affordable 3D printing technology to investigate fluid flow physics relevant to subsurface processes like CO2 storage. (researchgate.net)
In large scale subsurface injection of carbondioxide (CO ) as obtainable in carbon sequestration programs and in environmentally friendly hydraulic fracturing processes (using supercritical CO ), long term rock-fluid interaction can affect reservoir and seal rocks properties which are essential in monitoring the progress of these operations. (lsu.edu)

These traits can assist SOL in ameliorating the dissolution behavior and bioavailability of drugs loaded in self-nanoemulsifying drug delivery systems (SNEDDSs). (pharmaexcipients.com)
Dissolution of drug and its release from the dosage form have basic impact on bioavailability. (ijpsr.com)
If the drugs have less solubility in the gastric fluids then it will be less available for its absorption and due to this its bioavailability will be less. (ijpsr.com)
Thus, one of the greatest challenges the pharmaceutical industries faces today is the application of technological strategies towards improving the dissolution performance of drugs, producing formulations with adequate bioavailability and therapeutic effectiveness. (ijpsr.com)
Several methods are studied for increasing dissolution performance and bioavailability including micronization, Nanonisation, complexation with cyclodextrins, solid dispersion, self emulsifying system, liquisolid systems etc. (ijpsr.com)

In 1684, Great Britain granted the first formal extraction process patent. (wikipedia.org)
Shale oil extraction process decomposes oil shale and converts its kerogen into shale oil-a petroleum-like synthetic crude oil. (wikipedia.org)
The addition of caustic adjusts the pH of the extraction process, disperses clays, and acts as a water softener. (ualberta.ca)

By adjusting the gas concentration and reaction conditions, researchers can fine-tune reaction rates, selectivity, and optimize process efficiency. (gasesgrit.com)

The present study deals with geochemical characterization of mud fluids and sediments collected from Kunshuiping (KSP), Liyushan (LYS), Wushanting (WST), Sinyangnyuhu (SYNH), Hsiaokunshui (HKS) and Yenshuikeng (YSK) mud volcanoes in southwestern Taiwan. (edu.au)
Details on the processes and on the characterization, in terms of organic load, structural and textural properties of the resulting materials, are presented. (uab.cat)

Chapter 3 reports on the fabrication of hybrid products for biomedical applications by impregnating silica-based materials with a therapeutic agent trough dissolution in supercritical carbon dioxide. (uab.cat)

BioREP is an experimental platform for studying deep environments and characterising the natural biogeochemical processes and/or industrial processes that take place there. (brgm.fr)

Polymer Twin-Screw Extrusion System (with Supercritical CO 2 Capability) - SCF Processing Ltd. (pmbrc.org)
Several SD strategies, such as hot-melt extrusion , nanoextrusion, supercritical fluid processing, electrospinning , spray-drying, and freeze-drying are superior to other techniques in producing more effective SOL-based formulations. (pharmaexcipients.com)

This experimental investigation provides critical insights into fluid-mineral interactions involving CO2-rich fluids and represents a crucial step in ensuring the long-term security and technical feasibility of deploying global CCS and CO2-based geothermal energy. (ethz.ch)

Different impregnation processes (physical mixing, melting, wetting, sc-CO2 and subcritical CO2 impregnations) have been compared for each drug, in terms of drug recovery and crystallinity. (bvsalud.org)

While geomechanical properties such as rock stiffness, Poisson's ratio and fracture geometry largely govern fluid flow characteristics in deep micro-fractured formations. (lsu.edu)

However, only the E100-based formulations enabled a CBD immediate release, as formulations containing SOL formed a gel once in contact with the dissolution medium, reducing the drug dissolution rate. (bvsalud.org)
Formulations showed drug percentage close to 100% except for supercritical soluble drug formulations impregnated by using sc-CO2. (bvsalud.org)
Likewise, the resulting formulations are supposed to improve drugs' physical stability and solubility in biological fluids. (pharmaexcipients.com)

Ca +2 , Mg +2 ) on the fluid density alters the plume structure and favors faster dissolved plume development. (nature.com)
This generates a highly fast diminution of the SC CO2 density which comes to gas (and so a fluid with a low solving power) and finally leads to a recristallization of the solved substance. (top-supercritical.com)

and second, exploiting the utility of the supercritical fluids in the synthesis and functionalization of materials. (uab.cat)

Additionally, gas-assisted processes offer precise control in generating nanoparticles, microparticles, and solid dispersions, enabling targeted drug delivery and improving therapeutic outcomes. (gasesgrit.com)

Shale oil extraction is usually performed above ground (ex situ processing) by mining the oil shale and then treating it in processing facilities. (wikipedia.org)
Other modern technologies perform the processing underground (on-site or in situ processing) by applying heat and extracting the oil via oil wells. (wikipedia.org)
BioMOre Project : Extraction of copper from very deep environments using an in situ bioleaching process. (brgm.fr)

Crystallization process using ultrasound. (asiapharmaceutics.info)

The isotopic signature indicated that δ 18O-rich fluids may be associated with silicate and carbonate mineral released through water-rock interaction, along with dehydration of clay minerals. (edu.au)
GeoChemFoam is an open-source OpenFOAM-based numerical modelling toolbox that includes a range of custom packages to solve complex flow processes including multiphase transport with interface transfer, single-phase flow in multiscale porous media, and reactive transport with mineral dissolution. (researchgate.net)
Processing of fine particles in mineral beneficiation. (asiapharmaceutics.info)

Present study explores two methods of tailings treatment - ATA process and polymer. (ualberta.ca)
He specializes in polymer additives, polymer processing and formulation, material durability and the development of sealants and coatings. (chemtec.org)

The project "CO2-DISSOLVED" - directed by Prof. Christophe Kervevan - main aims were to develop a new and innovative approach combining Carbon Capture and Storage (process called CCS) and geothermal heat recovery process. (gouv.fr)
Jianying Jiao, Ye Zhang (2016) Multiscale Subgrid Models of Large Eddy Simulation for Turbulent flows, International Journal of Numerical Methods for Heat and Fluid Flow , Vol. 26, Issue, 5, pp. 1380 - 1390, 10.1108/HFF-01-2015-0009. (uwyo.edu)
Unlike foreign options, di- and triglycerides of palmitostearic acid) was lled into size 2 Spray drying is a process where a solution of drug substance and carrier is evaporated by spraying the solution as ne droplets into a chamber that is maintained under controlled conditions of heat, humidity, and airow. (binaryoptionstradinglist.com)

Depending on the uranium target used, the dissolution process involves the use of an alkaline or acid solution. (baypat.de)
The technique involves extraction and dissolution with precipitation. (techsciresearch.com)
This process involves reducing the size of the drug particles to 1 to 10 microns commonly by spray drying or by use of air attrition methods (fluid energy or jet mill).The process is also called as micro milling. (ijpsr.com)

thus, their absorption is a dissolution-controlled process [3,4] (see Table 4). (pharmaexcipients.com)
When oral route for administration of the drug is chosen then that drug should be sufficiently dissolved in gastric fluids for its proper absorption. (ijpsr.com)

The emulsions, either oil-in-water (O/W) or water-in-oil (W/O) emulsions, are inevitably formed during the industrial production processes and the daily household activities. (ualberta.ca)

This project was motivated by exploring a process of high viscosity bitumen displaced by. (ualberta.ca)

Analytical results suggested that the anoxic mud volcanic fluids are highly saline, implying connate water as the probable source. (edu.au)

Various outstanding reviews have been issued about the technologies in the dissolution enhancement of drugs using certain DDSs, such as micelles, solid dispersions (SD), nanosuspensions, and nanoemulsions. (pharmaexcipients.com)
There are several approaches for solubility enhancement which includes micronization, Nanonisation, use of salt forms, use of surfactant, solid dispersion, and supercritical fluid recrystalization etc. (ijpsr.com)
The mechanism for solubility enhancement includes increase in wettability and surface of drug available for dissolution. (ijpsr.com)

The BioREP (BioReactors for the Deep Environment) platform enables the reproduction of deep geological environments in order to study them and/or to characterise the effect of various natural and/or industrial processes taking place there. (brgm.fr)
According to Chen, the process effectively improves the long-term security of geological carbon dioxide storage. (vt.edu)

The spontaneous displacement of a fluid in another immiscible one on a solid surface is essential for many technical applications, such as painting, detergency, bitumen extraction and enhancing oil recovery. (ualberta.ca)
Holistic understanding of multiphase reactive flow mechanisms such as CO 2 dissolution, multiphase displacement, and snap-off events is vital for optimisation of large-scale industrial operations like CO 2 sequestration, enhanced oil recovery, and geothermal energy. (researchgate.net)

The traditional model of solid dissolution in porous media consists of three dissolution regimes (uniform, compact, wormhole)-or patterns-that are established depending on the relative dominance of reaction rate, flow, and diffusion. (researchgate.net)
They enhance dissolution rate primarily by promoting wetting and penetration of dissolution fluid into the solid drug particles. (ijpsr.com)

Water alternating gas (WAG) technique is used in the petroleum industry to inject carbon dioxide (CO 2 ) into underground formations either for sequestration or enhanced oil recovery (EOR) processes. (ac.ir)

Asphaltene precipitation and rock dissolution can significantly hinder the success of carbon dioxide flooding of asphaltenic crude oil in carbonate heterogeneous formations. (uaeu.ac.ae)

Among these, mineralogical trapping is the only mechanism that permanently sequesters the CO 2 while others are regarded as storage processes 10 . (nature.com)

The innovative process of this low cost CCS method deals also with many objectives as renewable energy production and greenhouse gas reduction. (gouv.fr)
Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles. (asiapharmaceutics.info)
Size reduction process is also termed as comminution or diminution or pulverizations. (asiapharmaceutics.info)

Anatomy1

Organisms6

Chemicals and Drugs18

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes3

Disciplines and Occupations2

Technology, Industry, Agriculture3

Health Care2

Solvent19

Subcritical and supercritical1

Solubility in supercritical1

Liquid or supercritical2

Brine7

Permeability8

Aqueous5

Chromatography1

Water-soluble1

SCFs2

Compounds5

Carbonate Rocks1

Pharmaceutics1

Solutes1

Interfacial2

Experiments3

Reactor1

Temperature5

Reactions6

Organic solvents1

Leakage1

Pore scale4

Subsurface3

Bioavailability5

Extraction process3

Selectivity1

Characterization2

Silica-based1

Biogeochemical processes1

Extrusion2

Interactions1

Impregnation processes1

Fracture1

Formulations3

Density2

Functionalization1

Therapeutic1

Situ3

Crystallization1

Mineral3

Polymer2

Heat3

Involves3

Absorption2

Emulsions1

Viscosity1

Saline1

Enhancement3

Geological2

Displacement2

Rate2

Sequestration1

Formations1

Mineralogical1

Reduction3