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  • urinary
  • The mean urinary excretion recovery following oral administration of sulfisoxazole is 97% within 48 hours, of which 52% is intact drug, with the remaining as the N 4 -acetylated metabolite. (drugs.com)
  • oral
  • Maximum plasma concentrations of intact sulfisoxazole following a single 2-gm oral dose of sulfisoxazole to healthy adult volunteers ranged from 127 to 211 mcg/mL (mean, 169 mcg/mL) and the time of peak plasma concentration ranged from 1 to 4 hours (mean, 2.5 hours). (drugs.com)
  • The elimination half-life of sulfisoxazole ranged from 4.6 to 7.8 hours after oral administration. (drugs.com)
  • This enzymatic splitting is presumed to be responsible for slower absorption and lower peak blood concentrations than are attained following administration of an equal oral dose of sulfisoxazole. (drugs.com)