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  • cell
  • We found that conjugation of cell penetrating peptide (CPP) to PNA is essential for the antimicrobial effect, with CPP1 [(KFF)3K] being the most effective against E. amylovora . (frontiersin.org)
  • synthesis
  • With the ability to use low volumes and accurate dispensing using digital syringe pumps, makes Initiator+ Alstra perfectly suited for small scale microwave peptide and peptidomimetic synthesis, especially when the use of expensive building blocks is required such as during PNA synthesis. (biotage.com)
  • C 10 H 18 N 4 O 6 , a compound intermediate in the synthesis of arginine, formed from citrulline and aspartic acid. (tabers.com)
  • molecular
  • They show promise for the development of gene therapeutic agents, diagnostic devices for genetic analysis, and as molecular tools for nucleic acid manipulations. (chalmers.se)
  • amide
  • In general, an appropriate solid support must be cleavable in acid, leaving a C-terminal amide, and be compatible with Fmoc chemistry. (linktech.co.uk)
  • Note that, due to the universal support, the C terminal is an amide rather than a free acid. (linktech.co.uk)
  • hydroxy acid
  • poly·lac·tic ac·id/ ( -lak´tik ) a hydrophobic hydroxy acid polymer that is formed into granules and used as a surgical dressing for dental extraction sites. (thefreedictionary.com)
  • moiety
  • The 2′-O-modified nucleosides of the invention include ring structures that position the sugar moiety of the nucleosides preferentially in 3′ endo geometries. (google.com)
  • salts
  • acids form salts by replacing all or part of the ionizable hydrogen with an electropositive element or radical. (thefreedictionary.com)
  • Any of the complex acids that occur as salts in bile, e.g., cholic, glycocholic, and taurocholic acids. (tabers.com)
  • bases
  • An acid reacts with a metal to form a salt, neutralizes bases, and turns litmus paper red. (tabers.com)
  • conjugation
  • We found that conjugation of cell penetrating peptide (CPP) to PNA is essential for the antimicrobial effect, with CPP1 [(KFF)3K] being the most effective against E. amylovora . (frontiersin.org)
  • purine
  • The purine nucleobases (Adenine A and Guanine G) and pyrimidine nucleobases (Cytosine C and Thymine T) are attached to the backbone through methylene carbonyl linkages. (biotage.com)
  • methods
  • The methods described may be applied, for example, to create solid-phase sources of chemical diversity, such as arrays of peptides, oligosaccharides, polymeric nucleic acid, etc., on a substrate, for use in screening for biological activity. (google.com)