• A colorless, crystalline organic acid that is important in the Krebs cycle and occurs naturally in amber. (dictionary.com)
  • The decrease in cellular succinic acid productivity observed during the anaerobic phase was found to be due to increased organic acid concentrations rather than medium osmolarity. (diva-portal.org)
  • The resultant engineered strains also lend insight into energetic and redox balance and elucidate mechanisms governing organic acid biosynthesis in this important natural SA-producing microbe. (asm.org)
  • Succinic acid an organic acid in the krebs cycle which is in most cells in our body is a good treatment for MS, and 99% of all other diseases in world. (thisisms.com)
  • In feather chemical industry, it can produce leather methyl eater agent or sulfonating succinic acid fatty amide ester disodium salt , which is a good washing aid. (opencroquet.org)
  • It could react with 1,2,3-trimethoxy-benzene, and obtain the 4-oxo-4-(2,3,4-trimethoxy-phenyl)-butyric acid methyl ester. (alfa.com)
  • Overall, this work demonstrates genetic modifications that can lead to succinic acid production improvements and identifies key flux determinants and new bottlenecks and energetic needs when removing by-product pathways in A. succinogenes metabolism. (asm.org)
  • BioAmber operates the world's only production plant for bio-succinic acid in Pomacle, France, with a 350,000 litre commercial scale fermenter. (chemicals-technology.com)
  • Evonik is proud to innovate together with BioAmber as a leading company in the bio-based succinic acid field, supporting our growth strategy based on resource efficiency. (chemicals-technology.com)
  • To expand succinic acid and BDO plant capacity to 34,000mt and 23,000mt respectively BioAmber, in association with Mitsui, has broken ground for a 17,000mt bio-succinic acid plant in Canada, which is expected to be operational in late 2013. (chemicals-technology.com)
  • The overall yields can be expressed on a mass basis where the pathway in Figure 1 results in a 0.66 gram succinic acid per gram of glucose consumed (g/g). (wikipedia.org)
  • With 13.0% share of total volume consumed in 2011, pharmaceutical industry was the second largest application segment for succinic acid. (bio-medicine.org)
  • 10 g L ), while minimal growth was observed at succinic acid concentrations above this threshold. (up.ac.za)
  • While the clinical effects observed in this trial do not support the use of threonine in the treatment of MS, the clear reduction of spasticity scores in treated patients sug¬ gests that additional studies, employing higher daily dos¬ ages or combination therapies, may identify a therapeutic role for this amino acid in the treatment of this disease. (thisisms.com)
  • The study delineates major factors which are driving and restraining the global demand for succinic acid and their impact over the forecast period. (bio-medicine.org)
  • As a food additive and dietary supplement, succinic acid is generally recognized as safe by the U.S. Food and Drug Administration. (wikipedia.org)
  • Moreover, it can produce high carbon fatty acid . (opencroquet.org)
  • Additionally, removal of competitive carbon pathways leads to higher-purity SA but also triggers the generation of by-products not previously described from this organism (e.g., lactic acid). (asm.org)
  • Four-carbon dicarboxylic acids have long been identified as particularly interesting precursors for bioproducts ( 1 ). (asm.org)
  • As a diprotic acid, succinic acid undergoes two successive deprotonation reactions: (CH2)2(CO2H)2 → (CH2)2(CO2H)(CO2)− + H+ (CH2)2(CO2H)(CO2)− → (CH2)2(CO2)22− + H+ The pKa of these processes are 4.3 and 5.6, respectively. (wikipedia.org)