Success of imatinib. Medical search. Frequent questions

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Anatomy15

K562 Cells Philadelphia Chromosome Cell Line, Tumor Neoplastic Stem Cells Bone Marrow Palate, Hard Tumor Cells, Cultured Chromosomes, Human, Pair 9 Hematopoietic Stem Cells Cells, Cultured Myeloid Progenitor Cells Interstitial Cells of Cajal Stromal Cells HL-60 Cells Cell Line

Organisms4

Papio anubis Mice, Nude Mice, SCID Introduced Species

Diseases48

Leukemia, Myelogenous, Chronic, BCR-ABL Positive Gastrointestinal Stromal Tumors Leukemia, Myeloid, Chronic-Phase Blast Crisis Gastrointestinal Neoplasms Philadelphia Chromosome Hypereosinophilic Syndrome Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative Leukemia, Myeloid, Accelerated Phase Dermatofibrosarcoma Precursor Cell Lymphoblastic Leukemia-Lymphoma Recurrence Neoplasm, Residual Disease Progression Muscle Cramp Fibromatosis, Aggressive Mastocytosis, Systemic Hypopigmentation Pregnancy Complications, Neoplastic Neoplasm Recurrence, Local Lichenoid Eruptions Leukemia Chordoma Scleroderma, Diffuse Cecal Neoplasms Neoplasms Disease Models, Animal Fibrosis Scleroderma, Systemic Chromosome Aberrations Gynecomastia Neutropenia Hypophosphatemia Splenomegaly Chronic Disease Nausea Edema Mastocytosis Neoplasm Metastasis Testicular Hydrocele Primary Myelofibrosis Brain Neoplasms Jejunal Neoplasms Leukemia, Myelomonocytic, Chronic Bone Neoplasms Exanthema Postoperative Complications Thrombocytopenia

Chemicals and Drugs56

Benzamides Piperazines Pyrimidines Fusion Proteins, bcr-abl Antineoplastic Agents Protein Kinase Inhibitors Proto-Oncogene Proteins c-kit Receptor, Platelet-Derived Growth Factor alpha Proto-Oncogene Proteins c-abl Protein-Tyrosine Kinases Thiazoles Organic Cation Transporter 1 Receptors, Platelet-Derived Growth Factor Harringtonines Interferon-alpha Pyrroles Enzyme Inhibitors Biomarkers, Pharmacological Cytarabine Indoles Proto-Oncogene Proteins c-sis mRNA Cleavage and Polyadenylation Factors P-Glycoprotein Hydroxyurea RNA, Messenger src-Family Kinases Platelet-Derived Growth Factor Oncogene Proteins v-abl Antigens, CD34 STAT5 Transcription Factor Neoplasm Proteins Stem Cell Factor Pyridines Orosomucoid Oncogene Proteins, Fusion ATP-Binding Cassette Transporters Phenylurea Compounds Phenyl Ethers Benzenesulfonates RNA, Neoplasm Quinolines Drugs, Investigational Cytochrome P-450 CYP3A Niacinamide Aniline Compounds Tumor Markers, Biological Phthalazines Receptor, Macrophage Colony-Stimulating Factor Pyridones Proto-Oncogene Proteins c-akt raf Kinases Aclarubicin Farnesyltranstransferase Oxazepines Benzylisoquinolines Iridium Radioisotopes

Analytical, Diagnostic and Therapeutic Techniques and Equipment73

Treatment Outcome Cytogenetic Analysis Remission Induction Disease-Free Survival Treatment Failure Drug Administration Schedule Follow-Up Studies Antineoplastic Combined Chemotherapy Protocols Retrospective Studies Survival Analysis Survival Rate Drug Monitoring Prognosis Salvage Therapy Clinical Trials as Topic Drug Approval Administration, Oral Reverse Transcriptase Polymerase Chain Reaction Inhibitory Concentration 50 Clinical Trials, Phase II as Topic Kaplan-Meier Estimate Prospective Studies In Situ Hybridization, Fluorescence Withholding Treatment DNA Mutational Analysis Transplantation, Homologous Combined Modality Therapy Early Termination of Clinical Trials Models, Economic Stem Cell Transplantation Clinical Trials, Phase III as Topic Hematopoietic Stem Cell Transplantation Drug Screening Assays, Antitumor Neoadjuvant Therapy Retreatment Therapies, Investigational Blotting, Western Immunohistochemistry Xenograft Model Antitumor Assays Molecular Targeted Therapy Tomography, X-Ray Computed Positron-Emission Tomography Models, Biological Polymerase Chain Reaction Clinical Trials, Phase I as Topic Chemotherapy, Adjuvant Disease Models, Animal Pilot Projects Probability Risk Assessment Models, Molecular Feasibility Studies Drug Evaluation, Preclinical Chromatography, High Pressure Liquid Maximum Tolerated Dose Stents Cohort Studies Flow Cytometry Risk Factors Gene Expression Profiling Blood Cell Count Catheter Ablation Karyotyping Drug Delivery Systems Reproducibility of Results Patient Selection Sensitivity and Specificity Drug Therapy, Combination Multivariate Analysis Randomized Controlled Trials as Topic Area Under Curve Mass Spectrometry Catheterization

Psychiatry and Psychology5

Sexual Behavior, Animal Mating Preference, Animal Nesting Behavior Achievement Competitive Behavior

Phenomena and Processes40

Drug Resistance, Neoplasm Genes, abl Philadelphia Chromosome Time Factors Mutation Dose-Response Relationship, Drug Gene Expression Regulation, Leukemic Apoptosis Cell Proliferation Genes, sis Reproduction Phosphorylation Drug Synergism Inhibitory Concentration 50 Signal Transduction Cell Survival Drug Interactions Chromosomes, Human, Pair 9 Gene Expression Regulation, Neoplastic Exons Protein Structure, Tertiary Point Mutation Pregnancy Genotype Probability Drug Resistance Chromosome Aberrations Cell Division Fertility Maximum Tolerated Dose Introduced Species Blood Cell Count Algorithms Genes, fms Cell Cycle Sensitivity and Specificity Drug Resistance, Multiple Area Under Curve Down-Regulation Phenotype

Disciplines and Occupations3

Cytogenetics Immunohistochemistry Pharmacogenetics

Anthropology, Education, Sociology and Social Phenomena2

Drug Approval United States Food and Drug Administration

Information Science2

Survival Rate Algorithms

Health Care31

Treatment Outcome Disease-Free Survival Treatment Failure Follow-Up Studies Retrospective Studies Survival Analysis Survival Rate Clinical Trials as Topic Clinical Trials, Phase II as Topic Kaplan-Meier Estimate Prospective Studies Withholding Treatment Early Termination of Clinical Trials Models, Economic Clinical Trials, Phase III as Topic Clinical Trials, Phase I as Topic United States Food and Drug Administration Pilot Projects Cost-Benefit Analysis Probability Risk Assessment Feasibility Studies Cohort Studies Risk Factors Introduced Species Reproducibility of Results Patient Selection Sensitivity and Specificity Multivariate Analysis Randomized Controlled Trials as Topic Area Under Curve

Geographicals1

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Psychiatry and Psychology Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Information Science Health Care Geographicals

Benzamides Piperazines Pyrimidines Leukemia, Myelogenous, Chronic, BCR-ABL Positive Gastrointestinal Stromal Tumors Fusion Proteins, bcr-abl Antineoplastic Agents Protein Kinase Inhibitors Leukemia, Myeloid, Chronic-Phase Proto-Oncogene Proteins c-kit Drug Resistance, Neoplasm Receptor, Platelet-Derived Growth Factor alpha Genes, abl Treatment Outcome K562 Cells Proto-Oncogene Proteins c-abl Blast Crisis Protein-Tyrosine Kinases Thiazoles Cytogenetic Analysis Gastrointestinal Neoplasms Philadelphia Chromosome Hypereosinophilic Syndrome Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative Remission Induction Organic Cation Transporter 1 Leukemia, Myeloid, Accelerated Phase Disease-Free Survival Time Factors Receptors, Platelet-Derived Growth Factor Harringtonines Cell Line, Tumor Mutation Treatment Failure Dose-Response Relationship, Drug Drug Administration Schedule Gene Expression Regulation, Leukemic Interferon-alpha Follow-Up Studies Apoptosis Dermatofibrosarcoma Precursor Cell Lymphoblastic Leukemia-Lymphoma Cell Proliferation Antineoplastic Combined Chemotherapy Protocols Pyrroles Retrospective Studies Recurrence Neoplasm, Residual Disease Progression Enzyme Inhibitors Genes, sis Survival Analysis Muscle Cramp Survival Rate Fibromatosis, Aggressive Reproduction Drug Monitoring Prognosis Mastocytosis, Systemic Salvage Therapy Phosphorylation Clinical Trials as Topic Hypopigmentation Drug Approval Biomarkers, Pharmacological Drug Synergism Cytogenetics Cytarabine Administration, Oral Indoles Reverse Transcriptase Polymerase Chain Reaction Inhibitory Concentration 50 Signal Transduction Clinical Trials, Phase II as Topic Kaplan-Meier Estimate Prospective Studies Proto-Oncogene Proteins c-sis Sexual Behavior, Animal mRNA Cleavage and Polyadenylation Factors P-Glycoprotein Hydroxyurea In Situ Hybridization, Fluorescence Withholding Treatment DNA Mutational Analysis Neoplastic Stem Cells Transplantation, Homologous Cell Survival RNA, Messenger src-Family Kinases Combined Modality Therapy Platelet-Derived Growth Factor Early Termination of Clinical Trials Drug Interactions Pregnancy Complications, Neoplastic Neoplasm Recurrence, Local Models, Economic Lichenoid Eruptions Leukemia Papio anubis Stem Cell Transplantation

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