• Prefoldin subunit 6 is a protein that in humans is encoded by the PFDN6 gene. (wikipedia.org)
  • The immunization antigen (13.34 kDa) is a protein containing 120 AA of recombinant Human Thyrostimulin beta subunit. (biovendor.com)
  • Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine. (ajtmh.org)
  • There are three vaccines at phase III stage with a similar choice of an antigen - the SARS-CoV-2 spike protein. (bizcommunity.com)
  • The S1 subunit (PDB I.D-6VSB) of the spike protein being reported to acts as receptor binding domain (RBD), binding to ACE-2 receptor with higher affinity. (ijpsonline.com)
  • It is responsible for intracellular protein turnover and it is also critically involved in many regulatory processes and, in higher eukaryotes, in antigen processing. (enzolifesciences.com)
  • The native protein substrates are recognised by subunits, some with ATP binding sites, of the outer 19S caps of the 26S proteasome.A second activator which can associate with the 20S proteasome in the absence of ATP is known as PA28 or the 11S regulator. (enzolifesciences.com)
  • The pure PA28 activator is a complex of two alternating subunits, PA28α and PA28β, which share approximately 50% homology but also show considerable similarity (30-40%) to a nuclear protein of unknown function, the Ki autoantigen (now referred to as PA28γ). (enzolifesciences.com)
  • Carcinoembryonic antigen (CEA) is a protein-polysaccharide complex present in colon cancers and in normal fetal intestine, pancreas, and liver. (msdmanuals.com)
  • Hsu SY, Nakabayashi K, Bhalla A. Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5. (biovendor.com)
  • Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor. (biovendor.com)
  • Integrin alpha 2 beta 1 is the non-covalent heterodimer of 160 kDa alpha 2 (CD49b) and 130 kDa beta 1 (CD29) type I transmembrane glycoprotein subunits and is one of six very late antigens on activated T cells, designated VLA2 (3). (novusbio.com)
  • Spike glycoprotein has two subunits, S1-responsible for its binding to host cell membrane receptors and S2-responsible for the fusion of viral and host cellular membrane[ 8 , 11 ]. (ijpsonline.com)
  • GSK's RSV older adult vaccine candidate contains a recombinant subunit prefusion RSV F glycoprotein antigen (RSVPreF3) combined with GSK's proprietary AS01 E adjuvant. (gsk.com)
  • Nasal insufflation of IL-11 causes AHR in wild-type mice while lung inflammation induced by antigen sensitization and challenge, which mimics features of atopic asthma in humans, is attenuated in mice genetically deficient in IL-11 receptor subunit alpha-1 (IL-11Ra1-deficient mice), a transmembrane receptor that is required along with glycoprotein 130 to transduce IL-11 intracellular signaling. (cdc.gov)
  • Prostate-specific antigen (PSA), a glycoprotein located in ductal epithelial cells of the prostate gland, can be detected in low concentrations in the sera of healthy men. (msdmanuals.com)
  • A low affinity interleukin-5 receptor subunit that combines with the CYTOKINE RECEPTOR COMMON BETA SUBUNIT to form a high affinity receptor for INTERLEUKIN-5. (harvard.edu)
  • Interleukin-11 receptor subunit alpha-1 is required for maximal airway responsiveness to methacholine after acute exposure to ozone (dataset). (cdc.gov)
  • The antibody was raised in rabbits by immunization with the recombinant Human Thyrostimulin beta subunit. (biovendor.com)
  • Immunoaffinity chromatography on a column with immobilized recombinant Human Thyrostimulin beta subunit. (biovendor.com)
  • The induced immune response against disease-causing organism through vaccine configures the body's immune cells in such a way so that they become capable of quickly recognizing and reacting to the same antigen in a more powerful manner when encountered again. (globenewswire.com)
  • Development of RTS,S/ AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant. (ajtmh.org)
  • Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research. (ajtmh.org)
  • Combination of two candidate subunit vaccine antigens elicits protective immunity to ricin and anthrax toxin in mice. (wadsworth.org)
  • In the current study immunoinformatics procedures were employed to introduce a novel multi-epitope subunit vaccine. (ijpsonline.com)
  • This multi-epitope vaccine can activate equally class I and II human leukocyte antigen and antibody mediated immune responses. (ijpsonline.com)
  • Docking results of the multi-epitope vaccine peptide with human leukocyte antigen class I and II alleles predicted efficient binding and the resulted docked models were stable during simulation. (ijpsonline.com)
  • The initial stair of vaccine development process is selecting those antigens that can be used as immunogens. (ijpsonline.com)
  • mycoides antigens as targets for a DIVA assay for use with a subunit vaccine for contagious bovine pleuropneumonia. (bvsalud.org)
  • This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. (thermofisher.com)
  • Serum antimitochondrial antibody targets non-organ-specific mitochondrial antigens numerically classified as M1-M9. (medscape.com)
  • 2-OADHC is composed of E1, E2, and E3 subunits, E2 being the immunodominant epitope targeted by antimitochondrial antibody-M2. (medscape.com)
  • Based on primary sequence comparisons, β subunits are predicted to be modular structures composed of five domains (A-E) that are related to the large family of membrane-associated guanylate kinase proteins. (jneurosci.org)
  • Using genetic engineering, scientists could make viral proteins (antigens) in the lab in bacterial or other cultures. (davidicke.com)
  • A capsid composed of 60 subunits is formed from 4 proteins-VP1 to VP4. (medscape.com)
  • MRRF attaches to the large ribosomal subunit in the cleft which has a peptidyl transferase center. (prospecbio.com)
  • The Integrin beta 1 subunit, also known as CD29, associates with multiple distinct Integrin alpha subunits. (rndsystems.com)
  • The alpha 5 subunit, also known as CD49e and VLA-5 alpha subunit, forms a heterodimer with the Integrin beta 1 subunit (CD29). (rndsystems.com)
  • CD51, an ~120 kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. (thermofisher.com)
  • Vaccines are biological agents that elicit an immune response against a specific antigen derived from disease-causing pathogen. (globenewswire.com)
  • Integrin alpha 2 is one of twelve integrin family alpha subunits that share the beta 1 subunit (1‑3). (novusbio.com)
  • It forms αβ heterodimers with the CD11 alpha subunits ITGAL (αL aka CD11a forming integrin LFA-1), ITGAM (αM aka CD11b, forming integrin Mac-1) and ITGAX (αX aka CD11c, forming integrin p150/95). (guidetopharmacology.org)
  • 1987) Heterogeneous mutations in the beta subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency. (guidetopharmacology.org)
  • Western blot analysis of HeLa cell lysate using Proteasome activator 11S gamma subunit, pAb (Prod. (enzolifesciences.com)
  • The mRNA vaccines can encode multiple antigens, strengthening the immune response against pathogens and enabling the targeting of multiple microbial variants [19] . (researchgate.net)
  • In cells of the mammalian immune system, PI3K is activated by receptors for antigen, cytokines, costimulatory molecules, and so on. (frontiersin.org)
  • This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. (nih.gov)
  • Recognizes the γ subunit of proteasome activator 11S. (enzolifesciences.com)
  • The catalytic core of this unusually large (2000kDa, 450Å in length) complex is formed by the 20S proteasome, a barrel shaped structure shown by electron microscopy to comprise of four rings each containing seven subunits. (enzolifesciences.com)
  • The finding that PA28 modulates the proteasome-catalysed production of antigenic peptides presented to the immune system on MHC class I molecules indicates a cellular function of this activator in antigen processing. (enzolifesciences.com)
  • Recent investigations in patients with fe- although the possibility that dried blood spot samples brile illness and petechial lesions identified R. asembo- from rural areas might have lower detection sensi- nensis DNA and antibodies for rickettsial antigens in tivity cannot be ruled out. (cdc.gov)
  • Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies. (wadsworth.org)
  • Immunity to these antigens reduces the likelihood of infection and lessens the severity of disease if infection occurs. (canada.ca)
  • 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. (nih.gov)
  • These hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. (biovendor.com)
  • The alpha-subunit combines with four distinct beta-subunits giving rise to four biologically active hormones in human: FSH, LH, TSH, and CG. (biovendor.com)
  • The Integrin beta 1 subunit has a broad tissue distribution with the exception of erythrocytes. (rndsystems.com)
  • The beta subunit is the CD18 ANTIGEN. (bvsalud.org)
  • The beta subunit is measured because it is specific for hCG. (msdmanuals.com)
  • Several isoforms of the interleukin-5 receptor alpha subunit exist due to multiple ALTERNATIVE SPLICING. (harvard.edu)
  • Ca 2+ channel β subunits regulate cell-surface expression and gating of voltage-dependent Ca 2+ channel α1 subunits. (jneurosci.org)
  • cough (pertussis) organisms, highly purified, non-infectious particles of Hepatitis B surface antigen (HBsAg) and Hib component as under consideration. (who.int)
  • Surface antigen of the Hepatitis B virus (HBV) is obtained by immunization, and also inquire about the recent health status of the child to be injected. (who.int)
  • Parents of a child with a family history y tétanos, organismos inactivados de tos ferina (pertussis), partículas no-infecciosas, altamente purificadas del antígeno de culturing genetically engineered Hansenula polymorpha yeast cells having the surface antigen gene of the Hepatitis B virus. (who.int)
  • Hepatitis B surface antigen (HBsAg) expressed in the cells of Hansenula polymorpha is purified through several chemical steps instructed regarding appropriate medical care in the unlikely event of a seizure. (who.int)
  • Influenza A viruses are classified into subtypes on the basis of two surface antigens: hemagglutinin (H) and neuraminidase (N). Three subtypes of hemagglutinin (H1, H2 and H3) and two subtypes of neuraminidase (N1 and N2) are recognized among influenza A viruses that have caused widespread human disease. (canada.ca)
  • The alpha subunit is the CD11C ANTIGEN, a surface antigen expressed on some myeloid cells. (bvsalud.org)
  • Interleukin-5 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Interleukin-5 Receptor alpha Subunit" by people in Harvard Catalyst Profiles by year, and whether "Interleukin-5 Receptor alpha Subunit" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Interleukin-5 Receptor alpha Subunit" by people in Profiles. (harvard.edu)
  • Echovirus serotypes 1 and 8 bind a subunit of the very late antigen (VLA) integrin molecule. (medscape.com)
  • The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. (nih.gov)
  • M2 is the most commonly recognized antigen complex, consisting of 2-oxo-acid dehydrogenase complex (2-OADHC) family located in the inner mitochondrial membrane. (medscape.com)
  • Each subunit then has a transmembrane sequence and a short cytoplasmic tail. (novusbio.com)
  • The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. (nih.gov)
  • Dendritic cells (DCs), which are the most important antigen-presenting cells (APCs) that send signals to the T cells, mainly participate in the pathogenesis of many diseases with immunoregulatory mechanisms, such as AR. (frontiersin.org)
  • Aim: To evaluate the involvement of Th2 cells in different periods of the active phase of experimental periodontal disease and expression of the R1 subunit of the receptor for IFN-γ during the early and advanced progression of the disease. (bvsalud.org)
  • In order to differentiate into Th1 or Th2 cells, CD4 T cells must become antigen-activated. (bvsalud.org)
  • Mus musculus L antigen family, member 3 (Lage3), mRNA. (genscript.com)
  • The N-terminal A domain differs among the four subtypes of Ca 2+ channel β subunits (β 1 -β 4 ) primarily as the result of two duplications of an ancestral gene containing multiple alternatively spliced exons. (jneurosci.org)
  • These subunits, with an apparent relative molecular weight of approximately 29kDa, form ringlike heteromeric complexes of ~200kDa possibly with an α 3 β 3 stoichiometry. (enzolifesciences.com)