• We enrolled all consecutive patients with a diagnosis of acute ischemic stroke admitted to the Internal Medicine Department at the University of Palermo between November 2006 and January 2009, and hospitalized control patients without a diagnosis of acute ischemic stroke. (nih.gov)
  • The early diagnosis and treatments of sepsis will improve the outcome of patients. (biomedcentral.com)
  • The aim of this study was to compare blood levels of presepsin (renamed from soluble CD14 subtype), procalcitonin (PCT), IL-6 and C-reactive protein (CRP) and to investigate the most useful biomarker for early diagnosis of sepsis. (biomedcentral.com)
  • Histological subtyping, which involves classifying mesothelioma types by certain microscopic features, plays a crucial role in diagnosis, treatment, and determining life expectancy in malignant pleural mesothelioma. (survivingmesothelioma.com)
  • True community-wide prevalence is unknown, although clinic studies estimate between 7.8% to 45.5% patients have a diagnosis of TKS, with a slight male preponderance. (scirp.org)
  • Fewer than 40% of patients with this subtype survive five years after their diagnosis. (medicalxpress.com)
  • Epigenetics has an important role in cancer pathogenesis and subtype diagnosis. (cdc.gov)
  • The diagnosis of dissociative subtype of posttraumatic stress disorder (PTSD) is made in patients who meet all the diagnostic criteria for PTSD and also experience persistent or recurrent dissociative symptoms (specifically, depersonalization and derealization) in response to a stressor. (msdmanuals.com)
  • General references The diagnosis of dissociative subtype of posttraumatic stress disorder (PTSD) is made in patients who meet all the diagnostic criteria for PTSD and also experience persistent or recurrent dissociative. (msdmanuals.com)
  • Clustering patients on this basis enabled the development of diagnostic classifiers (biomarkers) with high (82-93%) sensitivity and specificity for depression subtypes in multisite validation ( n = 711) and out-of-sample replication ( n = 477) data sets. (nature.com)
  • However, current label-free SERS approaches for DNA/RNA biomarker detection are limited to short and synthetic nucleic acid targets and have not been fully realized in clinical samples due to two possible reasons: (i) low target copies in limited patient samples and (ii) poor capability in identifying specific biomarkers from complex samples. (edu.au)
  • Given that copper preparations are used in the treatment of different types of cancer with a good therapeutic effect, it is crucial to explore biomarkers for HNSCC to better stratify patients and provide personalized treatment. (biomedcentral.com)
  • There are no established biomarkers to guide patient selection for neoadjuvant chemotherapy prior to radical cystectomy for muscle-invasive bladder cancer. (lu.se)
  • Recent clinical and genetic evidence suggests that it can be classified into 4 subtypes, which may have distinct clinical profiles. (psychiatrist.com)
  • By using functional magnetic resonance imaging (fMRI) in a large multisite sample ( n = 1,188), we show here that patients with depression can be subdivided into four neurophysiological subtypes ('biotypes') defined by distinct patterns of dysfunctional connectivity in limbic and frontostriatal networks. (nature.com)
  • This subtype is further divided into four distinct subtypes shown in the table below. (lls.org)
  • Applying our TPC algorithm to a PD clinical dataset, we identify 3 distinct subtypes/patient clusters, each with a characteristic progression profile. (santafe.edu)
  • When researchers discovered that breast cancers with lower levels of HER2 often respond to a trastuzumab-and-chemotherapy drug conjugate, they wondered whether such tumors represent a distinct subtype of breast cancer, with its own unique behavior and prognosis. (medicalxpress.com)
  • In this study, we sought to determine whether HER2-low represents a distinct subtype of breast cancer," said Tolaney. (medicalxpress.com)
  • Therefore HER2-low tumors should not be considered a distinct biologic subtype of breast cancer. (medicalxpress.com)
  • We analyzed whole-genome sequencing data from 2,511 individuals in the Pan-Cancer Analysis of Whole Genomes (PCAWG) study as well as 489 individuals from four prospective cohorts and found distinct regional mutation type-specific frequencies in tissue and cell-free DNA from patients with cancer that were associated with replication timing and other chromatin features. (nature.com)
  • Alexandra Lahtinen et al, Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma, Cancer Cell (2023). (medicalxpress.com)
  • As results of registrational trials might not answer all questions regarding safety and efficacy of ipilimumab in patients with advanced melanoma seen in daily clinical practice, the Dermatologic Cooperative Oncology Group conducted a phase II study to assess the efficacy and safety of ipilimumab in patients with different subtypes of metastatic melanoma. (uni-muenchen.de)
  • The objective of this study was to assess the association between psychological factors, particularly anxiety and marital disharmony, and the various subtypes of premature ejaculation. (psychiatrist.com)
  • Type 2 contains various subtypes. (wikipedia.org)
  • A group from Massachusetts General Hospital will highlight the potential for CT texture analysis to identify histological subtypes of non-small cell lung cancer. (auntminnie.com)
  • A new study, led by scientists from the International Agency for Research on Cancer (IARC) in collaboration with international partners, investigated trends in survival of oesophageal cancer by the two main histological subtypes (adenocarcinoma and squamous cell carcinoma) across seven countries with similar health-care access (Australia, Canada, Denmark, Ireland, New Zealand, Norway, and the United Kingdom). (who.int)
  • The increasing support for a dissociative subtype of post-traumatic stress disorder (PTSD-D) has led to its inclusion in DSM-5. (uni-bielefeld.de)
  • The most commonly observed influenza virus subtypes were B followed by A/H3 in ILI cases, and A/H1N1 followed by B in SARI cases. (who.int)
  • Objectives To classify subgroups of cancer-related symptoms in patients with multiple myeloma (MM) during treatment and examine between-group differences in demographic and clinical characteristics in addition to functional status. (bmj.com)
  • The identification of patients with high symptom burden management should focus on the assessment of demographic and clinical characteristics, in addition to functional status. (bmj.com)
  • This study assessed between-group differences in the demographic and clinical characteristics and functional status of patients with MM. (bmj.com)
  • Patient clinical characteristics did not include the evaluation of treatment response. (bmj.com)
  • These characteristics are common to both subtypes of papillary RCC. (renalandurologynews.com)
  • These clusters of symptoms, according to studies that have highlighted the role of possible confounding factors (such as demographic and clinical characteristics, active heroin use, lifetime psychiatric problems and kind of treatment received by the patients ), seem to constitute a trait rather than a state of the psychological structure of addiction. (bvsalud.org)
  • Interestingly, patients with the BCS2 subtype had a better prognosis than other subtypes. (frontiersin.org)
  • Therefore, novel treatments are needed to improve the prognosis of BLCA patients. (frontiersin.org)
  • Doctors at the University of Zagreb School of Medicine in Croatia say there is a subtype of epithelioid mesothelioma that carries as poor a prognosis as the sarcomatoid and biphasic types. (survivingmesothelioma.com)
  • Our results indicate that pleomorphic subtype is a predictor of poor prognosis and support classifying it with sarcomatoid or biphasic malignant pleural mesothelioma," the researchers conclude in Virchows Archiv, an international pathology journal. (survivingmesothelioma.com)
  • The prognosis is particularly poor in ovarian high grade serous carcinoma (HGSC), a subtype of ovarian cancer. (medicalxpress.com)
  • A CRG signature was defined that is associated with the prognosis of patients with HNSCC. (biomedcentral.com)
  • Since copper-induced death mechanisms are shared by genetic models of copper homeostasis dysregulation, copper homeostasis-related classification may impact on prognosis and the immune response of patients with HNSCC [ 3 ]. (biomedcentral.com)
  • In 2020, a study used MRS to predict the prognosis of colorectal cancer patients. (cdc.gov)
  • We enrolled 107 patients with acute ischemic stroke and 102 control subjects matched for age, sex, cardiovascular risk factors and previous cardiovascular morbidity. (nih.gov)
  • Stroke patients, compared to subjects without acute ischemic stroke, showed a higher mean Aix (103+/-3.5 mmHg vs. 99+/-4.6 mmHg) and PWV (11.8+/-3.3 m/s vs. 10.02+/-2.29 m/s). (nih.gov)
  • Our study shows that patients with acute ischemic stroke show higher arterial stiffness index values. (nih.gov)
  • Marie Louise Overgaard Svendsen » Publikationer » Ischemic stroke subtype is associated with outcome in thr. (au.dk)
  • OBJECTIVES: The impact of ischemic stroke subtype on clinical outcome in patients treated with intravenous tissue-type plasminogen activator (IV-tPA) is sparsely examined. (au.dk)
  • Patients and methods: We undertook a multicenter phase II study in melanoma patients irrespective of location of the primary melanoma. (uni-muenchen.de)
  • We developed GliomaPredict as a computational tool that allows the fast and reliable classification of glioma patients into one of six previously published stratified subtypes based on sets of extensively validated classifiers derived from hundreds of glioma transcriptomic profiles. (biomedcentral.com)
  • Recently, we established a robust and reliable glioma classification system that includes six hierarchically-nested subtypes and six sets of classifiers. (biomedcentral.com)
  • To translate our glioma classification system into a clinically useful application that is readily usable by clinicians and other statistically and computationally naïve users, we implemented GliomaPredict, a computational tool that allows anyone to reliably predict the subtype of a new glioma patient utilizing his/her tumor gene expression profile. (biomedcentral.com)
  • Recent studies suggest that molecular subtype classification holds promise for predicting chemotherapy response and/or survival benefit in this setting. (lu.se)
  • The precise classification system that best captures such a predictive effect, and the exact subtypes for which other treatment options are more beneficial remains to be established, preferably in prospective studies. (lu.se)
  • Some cancer subtypes have unique methylation profiles that could be used in classification. (cdc.gov)
  • Interventions The patients were categorised into subgroups based on cancer-related symptoms using a latent class analysis. (bmj.com)
  • Conclusions Patients with MM experienced varying degrees of symptoms during treatment. (bmj.com)
  • A latent class analysis was used to categorise cancer-related symptoms in Chinese patients undergoing treatment for multiple myeloma (MM). (bmj.com)
  • Patients with PTSD-D (N = 32, 27.6% of all patients with PTSD) reported significantly more current depressive symptoms, more current suicidal thoughts, more lifetime anxiety/tension, and more suicide attempts. (uni-bielefeld.de)
  • In a regression model, symptoms of depression in the last month and lifetime suicide attempts significantly predicted PTSD-D. These findings suggest that PTSD-D is related to additional psychopathology and to a more severe course of substance-related problems in patients with SUD, indicating that this group also has additional treatment needs. (uni-bielefeld.de)
  • The initial diagnostic evaluation of patients with any lymphoproliferative malignancy should include a careful history and physical examination, with close attention paid to the presence of systemic B symptoms, lymph node involvement, organomegaly, and evidence of cutaneous involvement. (medscape.com)
  • In 1978, 6 patients were described and 31 similar patients reviewed whose symptoms were consistent with a pericarotid syndrome. (medscape.com)
  • These subtypes may overlap, so you may experience a mix of symptoms from each of the three types. (healthline.com)
  • We conducted a study of the relationships between cognitive appraisal of IBS symptoms and negative mood for the subtypes of IBS. (springer.com)
  • this is an important endpoint for these patients, in whom rapid worsening of the disease can lead to worse symptoms and life-threatening situations. (prnewswire.com)
  • A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms 'worthlessness and being trapped', ' somatic symptoms ', ' sensitivity -psychoticism', ' panic - anxiety ' and ' violence - suicide ' in various populations of patients with heroin use disorder (HUD) and other substance use disorders (SUDs). (bvsalud.org)
  • Some patients with PTSD experience prominent dissociative symptoms. (msdmanuals.com)
  • Patients with dissociative symptoms and PTSD were characterized by higher levels of re-experiencing symptoms, onset of PTSD in childhood, high exposure to trauma and childhood adversities (prior to PTSD onset), severe role impairment (eg, difficulties in performing job responsibilities and completing work around the house) and suicidality. (msdmanuals.com)
  • However, extracutaneous involvement occurs in 5-10% of patients, mostly to the draining regional lymph nodes. (medscape.com)
  • Naohito Yamamoto Introduction: Sentinel node biopsy (SNB) has been increasingly performed for patients with lymph node (LN)-positive (cN1) breast cancer that converted to LN-negative (ycN0) status after. (karger.com)
  • Possible mechanisms for gram for breast cancer in southern Sweden issued 1991, pre- recurrence after treatment are low initial drug sensitivity or menopausal lymph node positive (N+) breast cancer patients an acquired drug resistance. (lu.se)
  • Radiotherapy was delivered to ipsilateral axil- cancer patients in the future, it is essential to increase our lary and supraclavicular lymph nodes and the remaining knowledge in mechanisms responsible for drug resistance, breast parenchyma after breast conservation surgery or tho- and to define reliable indicators for response to therapy. (lu.se)
  • Results In vitro, PR3 promoted monocyte-derived MGC formation using cells from patients with GPA but not from patients with MPA, and this was dependent on soluble interleukin 6 (IL-6), as well as monocyte MAC-1 and protease-activated receptor-2, found to be overexpressed in the cells of patients with GPA. (bmj.com)
  • LLS funds lifesaving blood cancer research around the world, provides free information and support services, and is the voice for all blood cancer patients seeking access to quality, affordable, coordinated care. (lls.org)
  • For non-muscle invasive bladder cancer (NMIBC), Bacille Calmette-Guerin (BCG) treatment is the standard immunotherapy for non-high risk NMIBC patients ( 3 ). (frontiersin.org)
  • However, most NMIBC patients will experience recurrence within 5 years, and a portion of patients will develop muscle-invasive bladder cancer (MIBC). (frontiersin.org)
  • Nevertheless, the 5-year survival rate for nonmetastatic MIBC patients (75% of newly diagnosed bladder cancer) is only 36% - 48% after first-line treatment, while the 5-year relative survival is 5% - 36% in metastatic MIBC ( 3 ). (frontiersin.org)
  • Among patients with low-grade, non-muscle invasive bladder cancer, intravesical UGN-102 appears to improve outcomes vs standard surgical treatment in two phase 3 trials. (cancernetwork.com)
  • Intravesical UGN-102 (mitomycin) improved clinical outcomes among patients with low-grade, intermediate-risk, non-muscle invasive bladder cancer (NMIBC), thereby meeting the primary end points of the phase 3 ATLAS (NCT04688931) and ENVISION trials (NCT05243550), according to a press release from UroGen Pharma. (cancernetwork.com)
  • While TURBT is the standard treatment for bladder cancer, the recurrent nature of low-grade, intermediate-risk non-[MIBC] means that patients will undergo multiple surgeries that come with risks for this older patient population," Sandip Prasad, MD, MPhil, director of Genitourinary Surgical Oncology at Morristown Medical Center/Atlantic Health System, said in the press release. (cancernetwork.com)
  • Jun Gong, MD, spoke with CancerNetwork® about the latest research from the journal ONCOLOGY® on elderly patients with muscle-invasive bladder cancer. (cancernetwork.com)
  • As a proof-of-concept clinical demonstration, we employed this strategy for non-invasive subtyping of prostate cancer (PCa). (edu.au)
  • We believe that our proposed assay could pave the way for simple and direct label-free SERS detection of multiple long nucleic acid sequences in patient samples, and thus facilitate rapid cancer molecular subtyping for personalized therapies. (edu.au)
  • The study analyzed data from 5,235 patients with non-metastatic HER2-negative breast cancer who underwent surgery for their disease at Dana-Farber Brigham Cancer Center. (medicalxpress.com)
  • Researchers found that among patients with hormone receptor-positive (HR-positive) or triple-negative tumors, the pathologic complete response rate-the percentage who had no signs of cancer after treatment-was essentially the same regardless of whether their tumors were HER2-low or HER2-0. (medicalxpress.com)
  • Moreover, among patients with HR-positive or triple-negative tumors, investigators found no differences between the HER2-low and HER2-0 groups in disease-free survival (the length of time that cancer remains undetectable) and overall survival. (medicalxpress.com)
  • 90% of patients with lung cancer, including those with stage I and II disease. (nature.com)
  • The fixed model was validated in an independent cohort, detected patients with cancer earlier than standard approaches and could be used to monitor response to therapy. (nature.com)
  • Methods: A prospective review of 49 consecutive patients with node-negative breast cancer treated with SLNB and intraoperative TIC and FS. (karger.com)
  • The researchers analyzed genomics data on cancer tumors collected in the DECIDER project from 148 patients with HGSC treated and recruited in Turku University Hospital. (medicalxpress.com)
  • We find that there is not sufficient evidence to conclude that the basal subtype of muscle-invasive bladder cancer responds well to chemotherapy, since only a minority of studies support this conclusion. (lu.se)
  • Our data have provided evidence for a comparable prediction of clinical outcome in CMF-treated breast cancer patients using conventional clinical variables and gene expression based markers. (lu.se)
  • In this paper, we review the history, epidemiology, and clinical subtypes of LP. We also review the histopathologic aspects of the disease, differential diagnoses, immunopathogenesis, and the clinical and genetic correlations. (hindawi.com)
  • To understand the molecular-genetic basis of functional specialization and identify potential drug targets specific to each neuron subtype, we performed a genome wide assessment of both gene expression and splicing across EXC, PV, SST and VIP neurons from male and female mouse brains. (jneurosci.org)
  • The complexities in B-cell lymphoma, including the common diffuse large B-cell lymphoma (DLBCL) subtype, originate from accumulated genetic anomalies during this differentiation process ( 3 ). (iiarjournals.org)
  • From April 1 through June 1, 1994, cases of acute HBV infection were identified in seven (5.3%) of 131 susceptible patients in center B. Of the two patients with chronic infections, one was identified as the source of the transmission through genetic sequencing of virus isolates from all infected patients. (cdc.gov)
  • 2014). genetic StudieS are carried out, uSing tuMour SaMPleS froM PatientS with excellent clinical data that have been collected at a PoPulation level or internationally, to Provide unique data coMbining the Pathology, geneticS, clinical featureS, and ePideMiology of tuMourS. (who.int)
  • The LLS mission: Cure leukemia, lymphoma, Hodgkin disease and myeloma, and improve the quality of life of patients and their families. (lls.org)
  • For patient education information, see Lymphoma . (medscape.com)
  • The World Health Organization (WHO) divides Hodgkin lymphoma into two main subtypes. (lls.org)
  • Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) affects about 5 percent of Hodgkin lymphoma patients. (lls.org)
  • A group in the Netherlands has built a radiomics model using FDG-PET scans that predicts disease-free survival odds in patients with relapsed lymphoma. (auntminnie.com)
  • Materials and Methods: Digital RNA quantification (Nanostring) of previously curated 188 B-cell lymphoma specimens across four subtypes, follicular lymphoma (FL), diffuse large B-cell lymphoma, not otherwise specified (DLBCL-NOS), primary testicular lymphoma (PTL), and plasmablastic lymphoma (PBL), was reanalyzed with focus on TBL1XR1 and NCOR1 expression, juxtaposing them with 730 ontogenically linked genes. (iiarjournals.org)
  • Here, we summarize and discuss the scientific literature examining transcriptomic or panel-based molecular subtyping applied to neoadjuvant chemotherapy-treated patient cohorts. (lu.se)
  • More evidence indicates that luminal-like subtypes may have the most improved outcomes after neoadjuvant chemotherapy. (lu.se)
  • Taken together, available studies suggest a role for molecular subtyping in stratifying patients for receiving neoadjuvant chemotherapy. (lu.se)
  • No study has evaluated both arterial stiffness indexes (PWV and Aix) in patients with an acute cerebrovascular event. (nih.gov)
  • The Trial of ORG 10172 in Acute Stroke Treatment criteria were used to establish the stroke subtype by 3 months. (au.dk)
  • The typical patient with GBS, which in most cases will manifest as acute inflammatory demyelinating polyradiculoneuropathy (AIDP), presents 2-4 weeks following a relatively benign respiratory or gastrointestinal illness with complaints of finger dysesthesias and proximal muscle weakness of the lower extremities. (medscape.com)
  • In these investigations, a case of acute HBV infection was defined as seroconversion from hepatitis B surface antigen (HBsAg)-negative to HBsAg-positive in a hemodialysis patient during the exposure period defined in each investigation. (cdc.gov)
  • From April 1 through May 18, 1994, cases of acute HBV infection were identified through routine seroscreening in 14 (70%) of 20 patients at center A, which opened in January 1994. (cdc.gov)
  • Further improvements in survival are needed, particularly for older patients and patients with squamous cell carcinoma. (who.int)
  • TPC is an easily generalizable method that identifies subtypes by clustering patients with similar disease trajectory profiles, based not only on Parkinson's Disease (PD) variable severity, but also on their complex patterns of evolution. (santafe.edu)
  • This resource, combining a unique new dataset and novel application of analysis methods to multiple relevant datasets, identifies numerous potential drug targets for manipulating circuit function, reveals neuron subtype-specific roles for disease-linked genes, and is useful for understanding gene expression changes observed in human patient brains. (jneurosci.org)
  • This analysis reveals numerous examples of neuron subtype-specific isoform usage with functional importance, identifies potential drug targets, and provides insight into the neuron subtypes involved in psychiatric disease. (jneurosci.org)
  • We sorted excitatory neurons and key inhibitory neuron subtypes from mouse brains and assessed differential mRNA expression. (jneurosci.org)
  • The molecular stratification of glioma patients into subtypes is the most direct way to translate genome-wide high-throughput data into information that can be used in a clinical setting. (biomedcentral.com)
  • In a training cohort of 43 patient urinary samples, we achieved 93.0% specificity, 95.3% sensitivity, and 94.2% accuracy. (edu.au)
  • The outcomes among stroke subtypes were compared with multivariable logistic regression. (au.dk)
  • Subcutaneous unfractionated or low ̶ molecular-weight heparin (LMWH) and thromboguards are often used in the treatment of immobile patients to prevent lower-extremity deep venous thrombosis (DVT) and consequent pulmonary embolism (PE). (medscape.com)
  • Performance anxiety during intercourse was significantly associated with the acquired subtype of premature ejaculation ( P = .011, Fisher exact test). (psychiatrist.com)
  • LP can significantly affect the quality of life of patients as well. (hindawi.com)
  • Augmentation Index and PWV values in lacunar subjects were significantly higher compared to values observed in LAAS, CEI and subtypes. (nih.gov)
  • And the presepsin values were significantly higher in the patients with the more severe septic condition (for example, sepsis, severe sepsis, septic shock). (biomedcentral.com)
  • The median TBL1XR1 expression was remarkably diminished in FL, yet, intriguingly, GCB-subtypes of DLBCL-NOS exhibited significantly enhanced expression compared to FL (p=0.001). (iiarjournals.org)
  • Background: Ipilimumab is an approved immunotherapy that has shown an overall survival benefit in patients with cutaneous metastatic melanoma in two phase III trials. (uni-muenchen.de)
  • Median survival for patients with advanced CTCL is less than 5 years. (lls.org)
  • For example, patients with biomarker-positive Stage IV disease have a median survival of less than one year. (lls.org)
  • In patients with biomarker-negative Stage IV disease, median survival is ~7 years. (lls.org)
  • In patients with multiple myeloma, an MRI radiomics machine-learning algorithm can identify minimal residual disease status, a biomarker linked with longer survival, according to a new study published in Clinical Radiology . (auntminnie.com)
  • To reach that conclusion, the team analyzed biopsy specimens and survival data from 108 mesothelioma patients diagnosed between 2000 and 2010 at the University's Institute of Pathology. (survivingmesothelioma.com)
  • Median overall survival for the patients with epithelioid mesothelioma was 10.5 months. (survivingmesothelioma.com)
  • Patients with biphasic mesothelioma had a median overall survival of 6.5 months, while those with sarcomatoid mesothelioma survived for a median of 4 months. (survivingmesothelioma.com)
  • However, for patients with a type of epithelioid mesothelioma called pleomorphic, the median survival was just 3 months. (survivingmesothelioma.com)
  • A team of medical researchers in Italy have achieved what they are calling "excellent" tumor control and survival results in malignant pleural mesothelioma patients using a combination of surgery, chemotherapy, and radiotherapy. (survivingmesothelioma.com)
  • The pivotal Phase 3 study enrolled over 500 patients and demonstrated an improvement in progression free survival (PFS) for patients treated with YONDELIS. (prnewswire.com)
  • Although survival improved across countries during the 20-year period, it remains low for both subtypes, and future research is warranted into early detection, treatment, and primary prevention. (who.int)
  • Patients with gemistocytic astrocytoma with oligodendroglial differentiation, IDH1 samples from a Li-Fraumeni family with and secondary glioblastoma with RRAS mutation, and 1p/19q loss, suggesting a TP53 germline mutation and multiple deletion tended to have shorter survival that FUBP1 immunohistochemistry is nervous system tumours revealed times than those without deletion. (who.int)
  • The US Food & Drug Administration (FDA) provides patient education as part of the questions and answers regarding breast implant-associated ALCL page on its Web site. (medscape.com)
  • Presepsin may be able to discriminate between patient groups with or without sepsis. (biomedcentral.com)
  • Because we do not know what mediates this patient-to-patient heterogeneity, we treat patients with the same standard-of-care therapies. (lls.org)
  • The findings can help therapies to become more accurate and help patients with HGSC. (medicalxpress.com)
  • The immune landscapes of each patient were visualized and revealed the heterogeneity within the BCS1 subtype. (frontiersin.org)
  • In the past, several groups have attempted to identify brain tumor subtypes computationally and stratify glioma patients into subtypes in terms of the gene expression pattern of their classifiers. (biomedcentral.com)
  • Three immune subtypes were classified based on immune-related gene expression profiles. (frontiersin.org)
  • These results reveal numerous examples where neuron subtype-specific gene expression, as well as splice-isoform usage, can explain functional differences between neuron subtypes, including in presynaptic plasticity, postsynaptic receptor function, and synaptic connectivity specification. (jneurosci.org)
  • Around 25% of patients with PC-ALCL show spontaneous regression. (medscape.com)
  • The associations between the psychopathological subtypes defined by SCL-90 categories and length of retention in treatment , after taking into account substance of abuse and other sociodemographic and clinical variables, were summarized using Cox regression. (bvsalud.org)
  • Results: 103 pretreated patients received at least one dose of ipilimumab, including 83 cutaneous, seven mucosal and 13 occult melanomas. (uni-muenchen.de)
  • Results In total, 216 patients completed the survey, with an average age of 60.3 years. (bmj.com)
  • Our tool utilizes a principle component analysis (PCA)-based approach to generate a visual representation of the analyses, quantifies the confidence of the underlying subtype assessment and presents results as a printable PDF file. (biomedcentral.com)
  • Our results are consistent with existing literature that shows an association between anxiety and premature ejaculation, particularly the acquired subtype. (psychiatrist.com)
  • The results of phylogenetic analysis showed subtypes A1 and B in 14 (58%) and 10 (42%) patients respectively. (ijbiotech.com)
  • The source-patient had been transferred from another center where he was known to have chronic infection, but his serologic status had not been reviewed on admission to center A. In addition, although all patients at center A were screened monthly for HBsAg, results were not reviewed routinely. (cdc.gov)
  • Clear cell RCC is the most common histologic subtype of malignant tumors of the kidney. (renalandurologynews.com)
  • In the current prospective study, 20 malignant pleural mesothelioma patients underwent radical pleurectomy/decortication followed by high doses of radiation. (survivingmesothelioma.com)
  • In summary, using PD as an example, we present an effective method for subtype identification in multidimensional longitudinal datasets, and early prediction of subtypes in individual patients. (santafe.edu)
  • To bridge this gap in knowledge, my lab has performed whole genome sequencing on a large clinically heterogeneous cohort of patient samples. (lls.org)
  • We show that TPC predicts the patient's disease subtype 4 years in advance with 72% accuracy for a longitudinal test cohort. (santafe.edu)
  • ABSTRACT Information on the prevalence of influenza, circulating virus subtypes and seasonality is essential for selecting strains for annual vaccines and for planning immunization programmes. (who.int)
  • Consensus clustering analysis was performed to identify immune subtypes using the ConsensusClusterPlus package. (frontiersin.org)
  • Based on our findings, we are better able to identify the subset of patients likely to benefit from such treatment," says Postdoctoral Researcher Jaana Oikkonen from the University of Helsinki. (medicalxpress.com)
  • Each clinicopathologic subtype can be further classified with respect to morphology, immunophenotype, and antigen markers. (medscape.com)
  • Any patients with persistent disease at 3 months in either arm underwent a TURBT, whereas those with a CR underwent assessment over long-term follow-up for evidence of recurrence. (cancernetwork.com)
  • MATERIAL AND METHODS: We conducted a single-center retrospective analysis of MRI-selected stroke patients treated with IV-tPA between 2004 and 2010. (au.dk)
  • CONCLUSIONS: Cardioembolic stroke patients were more likely to achieve early neurological improvement and favorable outcome compared with LVD stroke following MRI-based IV-tPA treatment. (au.dk)
  • With help from AI and radiomics analysis, dual-energy CT (DECT) can be an effective way to diagnose an aggressive macrotrabecular-massive subtype of hepatocellular carcinoma, a research team has found. (auntminnie.com)
  • An analysis of data from more than 5,000 patients showed that these "HER2-low" tumors were no different-in their response to treatment and long-term outcomes-from "HER2-0" tumors, which lack the HER2 protein entirely or have only minuscule amounts of it. (medicalxpress.com)
  • We examined relationships between PTSD-D and relevant variables in patients with substance use disorders (SUD). (uni-bielefeld.de)
  • Further research is being carried out on, for instance, what would be the easiest way to classify patients into the three groups identified," says Postdoctoral Researcher Alexandra Lahtinen from the University of Helsinki. (medicalxpress.com)
  • Through careful study of the cytogenetics of VHL patients, the gene at this locus was found to be a tumor suppressor gene associated with familial clear cell carcinomas as well as a large majority of sporadic RCC. (renalandurologynews.com)
  • Patients who had one or more systemic inflammatory response syndrome criteria were included in this study. (biomedcentral.com)
  • Forty-two patients were enrolled for the prospective study from June 2010 to December 2010. (biomedcentral.com)
  • The approval was based on recently published clinical efficacy and safety data from the Phase 3, randomized, open-label, controlled study (ET743-SAR-3007), which evaluated YONDELIS versus the chemotherapy agent dacarbazine, in patients with unresectable or metastatic LPS or LMS previously treated with an anthracycline and at least one additional chemotherapy regimen. (prnewswire.com)
  • We are proud that our Phase 3 study is the largest ever conducted in this patient population and we're delighted that patients in the U.S. can now benefit from the treatment. (prnewswire.com)
  • CONCLUSION: Our study in predominantly anticoagulated patients with AF shows that, reduction in LVEF is associated with higher thromboembolic, but not higher bleeding risk. (unich.it)
  • The present study aims to test whether the 5-factor psychopathological model of addiction correlates with the outcome (retention rate) of patients with SUDs entering a therapeutic community (TC) treatment . (bvsalud.org)
  • Our present study aims to investigate the effect of adrenalectomy on BP management within trHTN patients, and to explore clinical predictors for postoperative BP normalization. (degruyter.com)
  • In our current study, 117 patients diagnosed with trHTN and performed with unilateral adrenalectomy were consecutively enrolled, demographic and medical information were documented for baseline data collection. (degruyter.com)
  • In summary, this current study implicates that adrenalectomy is an efficacious and safe surgical strategy for BP management in trHTN patients. (degruyter.com)
  • Clarifying the effect of laparoscopic adrenalectomy on BP targeted in trHTN patients may be instructing for BP management within this population, whereas no study has reported this. (degruyter.com)
  • We studied the association between stroke subtype and clinical outcome in magnetic resonance imaging (MRI)-evaluated patients treated with IV-tPA. (au.dk)
  • Adjuvant polychemotherapy (e.g. with 58% to 68%) for patients under the age of 50.1 Besides an cyclophosphamide, methotrexate and 5-fluorouracil (CMF)) or improvement in clinical outcome, these figures indicate that anthracycline-containing regimes, produce substantial reduc- a large proportion of the patients will never recur after the tion in recurrence and mortality. (lu.se)
  • IBS patients as a general group report high levels of anxiety and depression. (springer.com)
  • Cluster 1 is referred to as Severe Insulin Deficient Diabetes (SIDD), which was present in 26.2% of patients and is characterised by the lowest body weight and waist circumference, as well as the lowest insulin reserve as measured by C-peptide levels. (ndtv.com)
  • Admission to the intensive care unit (ICU) should be considered for all patients with labile dysautonomia, a forced vital capacity of less than 20 mL/kg, or severe bulbar palsy. (medscape.com)