Substrate in bacterial. Medical search. Frequent questions

As central microbiota functions are determined by bacterial community networks, it is important to gain insight into the principles that govern bacteria-bacteria interactions. (nature.com)
At the same time, bacteria compete for substrates by employing diverse predatory mechanisms, like the production of bacteriocins [ 8 ]. (nature.com)
Bacterial attachment is favoured on recessed portions of patterned surfaces, and bacteria tend to attach preferentially to patterns in the micro or nanometre range rather than to smooth surfaces. (rsc.org)
Coarse Eco-Complete substrate includes live, Heterotrophic bacteria to convert fish waste into natural food for your plants. (liveaquaria.com)
Bacterial nanocellulose (BNC) is produced spontaneously as an extracellular polysaccharide by diverse types of bacteria. (icmab.es)
application of peptide substrates for diverse IgA1 proteases from Neisseria, Haemophilus, and Streptococcus bacteria. (tufts.edu)
Aerobic bacteria colonize the sponge providing a bacterial substrate to facilitate the nitrogen cycle. (americanaquariumproducts.com)
In addition, there are bacterial species that can infect people and cause disease, and there are bacteria that can produce natural products capable of healing people. (jove.com)
Bacteria often require a substrate to attach themselves to before they can multiply, and the attachment can be host specific or site specific. (who.int)
However, once feedings are begun, ample substrate is present for proliferation of luminal bacteria, which can penetrate the damaged intestinal wall, producing hydrogen gas. (msdmanuals.com)

In enzymology, a 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase (EC 1.1.1.152) is an enzyme that catalyzes the chemical reaction 3alpha-hydroxy-5beta-androstane-17-one + NAD+ ⇌ {\displaystyle \rightleftharpoons } 5beta-androstane-3,17-dione + NADH + H+ Thus, the two substrates of this enzyme are 3alpha-hydroxy-5beta-androstane-17-one and NAD+, whereas its 3 products are 5beta-androstane-3,17-dione, NADH, and H+. (wikipedia.org)
The Effect of Substrate Concentration, Enzyme. (educationindex.com)
Discussion: Once we were able to determine that the potato extract would react with PTU and catechol and the differing rates as to which the reaction occurred we were able to support our original hypothesis that enzymes reactivity is solely based on the amount of enzyme and substrate in a substance. (educationindex.com)
The structure of DhuD is unable to accommodate the substrate/cofactor, suggesting that conformational changes are essential to trigger enzyme catalysis. (rcsb.org)
The FLUOR DE LYS ® Substrate, which comprises an acetylated lysine side chain, is incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc. (enzolifesciences.com)
The activated enzyme then catalyzes the splitting of p-nitroanilin from the colorless substrate. (duke.edu)
Our results could be very useful to guide how much enzyme is needed for a biomass degradation process or determine what aspects of an enzyme to try to modify and what substrates are relevant to test activity on, where small model compounds do not properly mimic the more complex cell wall," said Johan Larsbrink, study researcher and associate professor of molecular enzymology at Chalmers University of Technology in Sweden. (lu.se)

Here, we investigated bacterial attachment, cell alignment and biofilm formation of Pseudomonas aeruginosa on periodic nano-pillar surfaces with different pillar spacing. (rsc.org)
In this study, we tested how a gradient of spatial habitat complexity in the form of fractal mazes influenced the growth, substrate degradation, and interactions of the bacterial strain Pseudomonas putida and the fungal strain Coprinopsis cinerea. (lu.se)

We found that rice bran and the other agricultural by-products tested significantly increased the abundances of a core group of anaerobic bacterial taxa (i.e. (usda.gov)
Minor modifications to existing wetland designs may improve the efficiency of water treatment by incorporating anaerobic bacterial processes. (cdc.gov)
An improvement in the odor emanating from the mouth is usually seen as the anaerobic bacterial count on a person's tongue is reduced. (medscape.com)

MS analysis of LotB and LotC identified different categories of host-interacting proteins and substrates. (elsevierpure.com)
The substrate specificity of ABC transporters is determined by its associated substrate-binding proteins (SBPs). (nih.gov)

Bacterial cells can colonize surfaces and form biofilms that consist of microbial cells embedded in extracellular polymeric substances (EPS). (rsc.org)
3 Bacterial biofilms can cause persistent human infections and can foul the surface of medical devices. (rsc.org)
Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)

Thus, we found that neither the Tanimoto similarity index nor ADME (absorption, distribution, metabolism, and excretion) properties appear useful for the identification of substrates (e.g., dipeptides) in YdgR-mediated drug transport. (ku.dk)
In fact, it is well known that fibres are the main substrate for bacterial metabolism. (springer.com)
This is the first report on the bacterial metabolism of glycosaminoglycan-derived unsaturated uronic acids by isomerase and dehydrogenase. (rcsb.org)

Bacterial substrate degradation strongly. (lu.se)
Bacterial substrate degradation strongly increased with habitat complexity, even more than bacterial biomass, up to an optimal depth, while the most remote parts of the mazes showed both decreased biomass and substrate degradation. (lu.se)
We demonstrate here that the sole effect of spatial microstructures affects microbial growth and substrate degradation, leading to differences in local microscale spatial availability. (lu.se)
de Gonzalo G, Colpa DI, Habib MH, Fraaije MW (2016) Bacterial enzymes involved in lignin degradation. (springer.com)

These results indicate that reproducible and effective implementation of ASD is achievable with alternative carbon substrates to rice bran. (usda.gov)
Here, we used replicated field trials of ASD to determine if rice bran and the alternative carbon substrates would elicit similar soil bacterial communities (characterized via amplicon sequencing of the 16S rRNA gene v4 region) and to assess if any observed community shifts were consistent across the repeated trials. (usda.gov)

This work provides tools that will help investigate the roles of IgA1 proteases in bacterial colonization, immune evasion, and infection. (tufts.edu)

A study in Nature Communications reveals one key piece of the puzzle using bacterial enzymes. (lu.se)
[ 4-6 ] The gut microbiota performs a number of crucial functions for the host including priming the immune system, breakdown of dietary substrates inaccessible to host enzymes, and detoxification of xenobiotics. (medscape.com)

The other compounds tested were neither inhibitors nor substrates. (ku.dk)
By exploiting saturation transfer difference (STD) NMR spectroscopy, the structural requirements necessary for API substrate recognition and binding were identified, with the aim of designing new API inhibitors. (unimib.it)

Researchers from the Nanoparticles and Nanocomposites (NN) Group at the Institute of Materials Science of Barcelona (ICMAB, CSIC), Anna Roig, Anna Laromaine and Irene Anton, have published an article on Small about the production and characterization of bacterial nanocellulose (BNC) to be used as a bandage to secure LSC to the cornea. (icmab.es)

The mouth is home to hundreds of bacterial species with various nutritional preferences. (medscape.com)

In mammalian cells, there are three types of PI3K with distinct substrate specificities. (frontiersin.org)

Membranes are thereafter incubated with a horseradish-peroxidase substrate (ECL Western blotting detection reagents, Amersham-Pharmacia Biotech, Sweden) and the chemiluminescent signal is assessed in a LumiImagerTM Workstation equipped with a CCD camera (Boehringer-Mannheim, Germany). (cdc.gov)

PBS dilutions of sonicated bacterial extracts derived from each of the above species were brought to an optical density of 1, using a spectrophotometer (Ultrospec III, Pharmacia, Sweden) set at a wavelength of 600 nm. (cdc.gov)

Proton-dependent oligopeptide transporters (POTs) are recognized for their substrate promiscuity due to their ability to transport a wide range of substrates. (ku.dk)

IgA1 proteases from diverse strains showed unexpected selectivity profiles among peptide substrates derived from autoproteolytic sites. (tufts.edu)
Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)

More than half a century ago, Heukelekian and Heller [6] showed that at low nutrient concentrations substrate plays an important role in bacterial multiplication. (who.int)

This high-throughput method enabled us to screen hundreds of dipeptides with various side-chains, and subsequently, to determine the substrate profile of the dipeptide permease. (nih.gov)

Together, our results provide new structural insights into bacterial OTU-DUBs and indicate distinct roles in host-pathogen interactions. (elsevierpure.com)

MlaA represents a lipid transport protein that selectively removes outer leaflet phospholipids to help maintain the essential barrier function of the bacterial OM. (nature.com)
The structures show that both substrate translocation and release involve movements of the bulky transport domain through the lipid bilayer. (elifesciences.org)

Very remote spaces showing a slower turnover of substrates illustrate a mechanism which may contribute to the long-term storage of organic matter in soils. (lu.se)
Coarse substrate packed in Liquid Amazon buffered "Black Water" solution, Eco-Complete offers immediate organic water conditioning - no rinsing required. (liveaquaria.com)
Bacterial sulfate reduction is a naturally occurring process that proceeds only in the absence of oxygen and in the presence of sufficient organic carbon and sulfate. (cdc.gov)
An experimental wetland was designed and built to maximize contact between mine drainage and the anaerobic zone of the organic substrate, where sulfate reduction takes place. (cdc.gov)
The observed improvement in water quality was due to the inherent chemical characteristics of the organic substrate as well as to bacterial activity. (cdc.gov)
Bacterial sulfate reduction rates in the organic substrate ranged from 0.002 to 0.6 Mmol/l-sediment/day. (cdc.gov)

Here, we focused on the growth and metabolic interactions of the Oligo-Mouse-Microbiota (OMM 12 ) synthetic bacterial community, which is increasingly used as a model system in gut microbiome research. (nature.com)

Bacterial adhesion on medical devices leads to severe infections, which trouble people a lot. (hindawi.com)
A group from Colombia has developed a superficial modification technique to decrease bacterial adhesion on steel 316L by one fold. (hindawi.com)
Importantly, this magic bacterial adhesion thin film can also be transferred to other substrates. (hindawi.com)
Biofilm formation requires three different stages: cell attachment to a solid substrate, adhesion, and growth. (intechopen.com)

Glycosaminoglycans in mammalian extracellular matrices are degraded to their constituents, unsaturated uronic (glucuronic/iduronic) acids and amino sugars, through successive reactions of bacterial polysaccharide lyase and unsaturated glucuronyl hydrolase. (rcsb.org)

New therapies are important because treating some bacterial infections with conventional antibiotics can cause the release of more toxins and may worsen disease outcome. (sciencedaily.com)

Eco-Complete Planted Aquarium substrate contains all the mineral nutrients needed for luxuriant plant growth. (liveaquaria.com)

The results indicated that the dominant bacterial phyla in the samples were Acidobacteriota , Proteobacteria , Actinobacteriota , Chloroflexi . (researchsquare.com)
[ 1 ] In healthy individuals, it is dominated by 2 major bacterial phyla: Bacteroidetes and Firmicutes, with smaller representation from Proteobacteria and Actinobacteria. (medscape.com)

Surface topography designed to achieve spatial segregation has shown promise in delaying bacterial attachment and biofilm growth. (rsc.org)
In particular, surface modifications that physically create rational surface topographies have attracted attention in recent years, and have shown to inhibit bacterial attachment and biofilm growth without the use of antimicrobials. (rsc.org)
These bacterial taxa have the genomic potential to produce compounds previously shown to inhibit growth of plant pathogens. (usda.gov)
This methodology utilizes agar as a medium for bacterial growth, a process termed, "culturable technology. (jove.com)
Mycosphere in soils: hyphal influence on bacterial dispersal and growth when colonizing pristine environments. (lu.se)

Even synthetic substrates made by electrospinning seem promising. (icmab.es)

We found that DppA2 shows the highest flexibility on substrate recognition and that DppA2 and DppA4 have a higher tendency to utilize tripeptides. (nih.gov)

Dutta N, Mukhopadhyay A, Dasgupta AK, Chakrabarti K (2014) Improved production of reducing sugars from rice husk and rice straw using bacterial cellulase and xylanase activated with hydroxyapatite nanoparticles. (springer.com)
In this study, we conducted replicated field trials of ASD using rice bran and other agricultural by-products to (1) determine if we would observe similar bacterial community shifts between the carbon sources and (2) assess if the bacterial community shifts would be consistent between trials. (usda.gov)
Rice bran is the standard carbon source for ASD and we identified three other substrates (molasses, mustard seed meal, and tomato pomace) that are similar in efficacy to rice bran at generating and sustaining soil anoxia and reducing the population of an introduced plant pathogen. (usda.gov)
avenae , the causal agent of bacterial stripe of rice, in rice seed and tissue soaks as well as bacterial cultures. (agdia.com)

Unsurpassed macro-porosity for healthy roots and bacterial efficiency. (liveaquaria.com)

A newly discovered receptor in a strain of Escherichia coli can be blocked to avert infection, a finding that might aid in developing better therapies to treat bacterial infections resulting in food poisoning, diarrhea or plague. (sciencedaily.com)
This receptor is found in many pathogens, so we can use this knowledge to design specific antagonists to block bacterial infections," said Dr. Vanessa Sperandio, senior author of the study and assistant professor of microbiology at UT Southwestern. (sciencedaily.com)
This knowledge opens the door to further understanding of the signaling processes between microbes and humans and to the development of novel treatments of bacterial infections with antagonists to these signals, Dr. Sperandio said. (sciencedaily.com)

It is believed that an ischemic insult damages the intestinal lining, leading to increased intestinal permeability and leaving the intestine susceptible to bacterial invasion. (msdmanuals.com)

Bacterial meningitis is a severe infectious disease with high mortality. (tufts.edu)

Diverse film properties were achieved by increasing the substrate temperature at the deposition. (muni.cz)

Metabolic network reconstruction in combination with metabolomics analysis of bacterial culture supernatants provided insights into the metabolic potential and activity of the individual community members. (nature.com)

Surface patterning is an important determinant of bacterial attachment. (rsc.org)

Threadlike structures ("bacterial nanotubes") protruded from the majority of bacterial cells and appeared to link cells directly with the nanopillars. (rsc.org)
We report Cryo-EM structures of Glt Ph reconstituted into nanodiscs, including those structurally constrained in the cytoplasm-facing state and either apo, bound to sodium ions only, substrate, or blockers. (elifesciences.org)

Carnosine was the only compound observed to be a YdgR substrate based on cell-based transport assays and molecular docking. (ku.dk)
In a study to better understand the neuroanatomical substrates and molecular pathways underlying ethanol sensitivity in Drosophila, we found that genetic manipulation of a small group of insulin producing cells results in a strong increase in sensitivity to ethanol-induced sedation. (escholarship.org)

Naturally rich substrate coloration encourages the most vibrant coloration in fishes and reduces fish stress. (liveaquaria.com)

This is the peer reviewed version of the following article: Choudary, S. K., Qiu, J., Plaut, A. G. and Kritzer, J. A. (2013), Versatile Substrates and Probes for IgA1 Protease Activity. (tufts.edu)

Studies showing that murine fibroblast cell lines are susceptible to infection with mouse-adapted scrapie agent ( 11 , 12 ) increased concern that nonneuronal cell substrates used to propagate viruses for vaccine production might become infected with a TSE agent contaminating some component of culture medium, especially bovine serum ( 13 ). (cdc.gov)

Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. (medscape.com)

A dipeptide-fluorophore conjugate, H-(β-Ala)-Lys(AMCA)-OH, is a well-known substrate of the transporter YdgR that is commonly used as a fluorescent reporter. (ku.dk)

2 pounds of substrate per gallon is optimal. (liveaquaria.com)

This document describes a protocol for a quantitative detection of Gram negative bacterial endotoxin in nanoparticle preparations using an end-point Limulus Amebocyte Lysate (LAL) assay. (duke.edu)

Our results provide a first overview of the substrate pattern of the ABC dipeptide transport machinery in P. aeruginosa. (nih.gov)

Wait until Abx Tx complete to administer live bacterial vaccine. (medscape.com)

In order to understand the substrate space of YdgR, we used this dipeptide as a bait reference, when screening an ensemble of compounds (previously tested in PEPT/PTR/NPF space) via a cheminformatic analysis based on the Tanimoto similarity index. (ku.dk)
The Gram-negative bacterial outer membrane (OM) is a unique bilayer that forms an efficient permeation barrier to protect the cell from noxious compounds 1 , 2 . (nature.com)

We propose that bacterial nanotubes are produced to aid in cell-surface or cell-cell connections. (rsc.org)
The substrate is cell-permeable and serves as the basis for the HDAC Cellular Activity Assay Kit (Prod. (enzolifesciences.com)

IgA1 proteases have unique selectivity, with few reported substrates other than IgA1 from human tissue. (tufts.edu)
Several irrigating solutions might be used during chemomechanical preparation of infected root canals, to increase bacterial elimination and facilitates removal of necrotic pulp tissue and dentine chips from root canal. (bvsalud.org)

Anatomy13

Organisms10

Chemicals and Drugs136

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

Phenomena and Processes66

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science5

Health Care3

Bacteria10

Enzyme7

Pseudomonas2

Anaerobic bacterial3

Proteins2

Biofilms3

Metabolism3

Degradation4

Carbon substrates2

Colonization1

Enzymes2

Inhibitors2

Characterization1

Hundreds of bacterial species1

Specificities1

Membranes1

Species1

Transporters1

Strains2

Nutrient1

Dipeptides1

Structural1

Lipid2

Organic6

Interactions1

Adhesion4

Polysaccharide1

Antibiotics1

Nutrients1

Phyla2

Growth5

Synthetic1

Recognition1

Rice4

Efficiency1

Infections3

Invasion1

Infectious1

Temperature1

Metabolic1

Attachment1

Structures2

Molecular2

Naturally1

Peer reviewed1

Infection1

Exposure1

Fluorescent1

Optimal1

Detection1

Results1

Vaccine1

Compounds2

Cell2

Tissue2