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MitochondrialVitroMetabolismMetabolicCellHumanResults
Mitochondrial1
  • Herein, effects of mitochondrial transplantation via different approaches in breast cancer were investigated. (biomedcentral.com)
Vitro2
  • Furthermore, in vitro culturing conditions can have a large effect on cell growth (11-13) and thus, cellular metabolism. (researchsquare.com)
  • A few studies have documented biological effects of urolithins in vitro, including antiproliferation in cancer cell models10, anti-inflammation11 and benefits on lipid metabolism12, although a clear biological pathway has not yet been described. (lsd1receptor.com)
Metabolism1
  • To test the first possibility, we measured the effect of UA on bacterial metabolism by measuring the growth of two Escherichia coli strains, OP50 and HT115, after treatment with UA. (lsd1receptor.com)
Metabolic4
  • Bitter melon is attracting increasing attention because of its beneficial effects against obesity and type 2 diabetes-associated metabolic disorder (Fan et al. (excli.de)
  • This shift in metabolic pathways is called "The Warburg Effect" and results in the accumulation of lactate regardless of oxygen availability (4). (researchsquare.com)
  • This can confound metabolic analyses compared with the primary tumour due to the effects from the tumour microenvironment (10). (researchsquare.com)
  • The biological effects of urolithins remain poorly characterized, despite wide-spread human exposure via the dietary consumption of their metabolic precursors, the ellagitannins, which are found in the pomegranate fruit, as well as in nuts and berries. (lsd1receptor.com)
Cell2
  • We tested four major extracts of M. charantia and found that momordicine I reduced glioma cell viability without serious cytotoxic effects on astrocytes. (excli.de)
  • We further explored whether the antiglioma effect of momordicine I may be related to cell cycle modulation and DLGPA5 expression. (excli.de)
Human1
  • Recent crystal structures of yeast Atm1 and human ABCB10 have been key to identifying substrate-binding sites and transport. (silverchair.com)
Results1
  • Our results indicate that the cytotoxic effect of momordicine I on glioma cells suggests its potential therapeutic application to GBM treatment. (excli.de)