Suboptimal adherence. Medical search. Frequent questions

An analysis of medication possession ratios suggests that only 73.1% of participants receiving antiretroviral therapy (ART) meet the minimum adherence threshold needed to prevent drug resistance, virologic failure, or other adverse outcomes. (pharmacytimes.com)
But we need more than 90% adherence for successful outcomes of HIV treatment. (theseoultimes.com)
Regular physical activity (PA) can improve health outcomes in cancer survivors, but the rate of adherence to PA recommendations among middle-aged survivors is unclear. (cdc.gov)
The overarching emphasis is on the development of feasible interventions to improve and sustain PrEP or ART adherence which could be rapidly implemented in clinical, community, and policy environments to improve HIV treatment and prevention outcomes. (nih.gov)
2021) Utilizing patient perception of group treatment environment in exploring medication adherence, social support, and quality of life outcomes in people who inject drugs with Hepatitis C. Journal of Substance Abuse Treatment, Jul, 126, 108459. (clemson.edu)
However, even with DOT, treatment completion is still challenging and cure rates and outcomes remain suboptimal [3]. (ersjournals.com)
However, medication adherence and persistence are suboptimal in these patients, resulting in poor patient outcomes. (ahdbonline.com)
A growing public health concern in senior patients, many of whom have multiple chronic conditions, polypharmacy paves the way for medication non-adherence, drug reactions, adverse events, and poor health outcomes, as well as increased use of healthcare services and rising costs. (businesswire.com)
All our work is based on evidence in the research and practice literature: many problems and bad outcomes are attributable to suboptimal communication, including poor patient adherence, increased risk of malpractice action and complaints, low patient and provider satisfaction, low levels of patient and provider engagement, decreased diagnostic accuracy and unfavorable net promoter scores. (guidestar.org)
IHC's TTT model is a proven strategy to strengthen clinician's communication skills, with measurable results for improved patient adherence and health outcomes, greater patient and provider satisfaction, lower malpractice risk and enhanced patient and provider engagement. (guidestar.org)

Most patients receiving antiretroviral therapy do not meet the minimum threshold for medication adherence, but patients on single-tablet medication regimens tended to meet that threshold. (pharmacytimes.com)
The analysis, published in the January 2014 edition of Journal of Managed Care Pharmacy , also found significantly better adherence to single-tablet regimens (STRs) , allowing participants on those regimens to reach the 90% minimum adherence threshold. (pharmacytimes.com)
Researchers used an assigned last office visit date from January 1, 2010, through August 31, 2010, plus 120 days to define participants' antiretroviral regimens, and evaluated adherence from October 19, 2010, to October 18, 2011, using the pharmacy claims data. (pharmacytimes.com)
By applying the health belief modal, this study attempts to explore the risk perception of peritonitis and the sociopsychological factors that contribute to suboptimal adherence to the therapeutic regimens among patients on CAPD. (edu.hk)
The patients perceived autonomy and independence and minimizing the sense of guilt as the benefits of adherence to therapeutic regimens. (edu.hk)
Researchers and pharmacists have helped by offering simplified treatment regimens that lead to better long term medication adherence, improve quality of life, avoid long term toxicities, and reduce risk of virologic failure. (theseoultimes.com)
Adherence to medical regimens is a major problem in the management of any chronic disease. (medpagetoday.com)
This Funding Opportunity Announcement (FOA) encourages research to understand and promote adherence to antiretroviral (ARV) regimens for HIV treatment and prevention. (nih.gov)
The success of complex antiretroviral regimens is dependent on consistent adherence of patients to the drugs. (who.int)

Therefore, targeted interventions to improve adherence to PA among cancer survivors are needed. (cdc.gov)
Any descriptive studies should be undertaken with the aim of informing the design or mechanisms of adherence interventions. (nih.gov)
As non-adherence can result in more disease activity and a lower quality of life, interventions to improve adherence are warranted. (nivel.nl)
Drivers of non-adherence, poor retention in care, and mental health problems may differ by mode of infection, requiring tailored interventions. (ucl.ac.uk)
The purpose of this position statement was to translate evidence on interventions that increase CR enrollment and adherence into implementable recommendations. (bvsalud.org)
Conclusions: This information may be used to develop more effective interventions for promoting HCW adherence to TB prevention policies. (cdc.gov)

The medical provider or clinician (in many cases, an experienced asthma educator) needs to assume the task of addressing the issue of adherence. (medpagetoday.com)
This issue of adherence is going to be the single biggest problem in chronic disease states, especially type 2 diabetes," said Dr Edelman. (ahdbonline.com)

Perceived barriers to adherence included social activities and work, cost of treatment, fatigue, and environmental constraints. (edu.hk)
In-depth, qualitative analysis was conducted to identify facilitators and barriers to adherence. (cdc.gov)

Perceived need to take medication is associated with medication non-adherence in patients with rheumatoid arthritis. (nivel.nl)
Medication non-adherence (no/yes) was measured using the Compliance Questionnaire Rheumatology (CQR). (nivel.nl)
Weaker) necessity beliefs about medication, a more unfavorable balance between necessity and concern beliefs about medication, and having an indifferent attitude towards medication are associated with medication non-adherence. (nivel.nl)

Most patients with type 2 diabetes (T2D) have suboptimal adherence to recommended diet, physical activity, and/or medication. (harvard.edu)
He cited data showing that in a group of patients with type 2 diabetes, poor adherence translated to increased risk for hospitalization and all-cause mortality. (ahdbonline.com)

Researchers aimed to evaluate medication adherence in the US Department of Health and Human Services 2011 Antiretroviral Guidelines, so medication possession ratio was not evaluated in patients on ART that was not indicated as a first-line therapy in treatment-naïve patients or in those receiving therapies classified as "other. (pharmacytimes.com)
Severely energy-restricted diets (SERDs) are an effective treatment for obesity, however, adherence to such diets is often perceived as poor by healthcare professionals. (mdpi.com)
Additionally, drug resistances can be acquired or transmitted due to suboptimal pharmokinetics or lack of patient adherence to treatment. (wikipedia.org)
The major determinant of the outcome of treatment is patient adherence to the drug regimen. (cdc.gov)
Adherence to treatment plans is generally suboptimal and the patients frequently leave the hospital against medical advice. (nih.gov)
At the recently concluded 6th National Conference of AIDS Society of India (ASICON 2013), Dr K Satish, a senior Pulmonologist from Bangalore, stressed upon the importance of adherence to both care and medication for the success of any treatment programme including HIV/AIDS. (theseoultimes.com)
He defined adherence as the patient s active participation in planning care and treatment and is based upon shared decision making between patient and provider. (theseoultimes.com)
Likewise non-adherence to antiretroviral therapy (ART) in treatment of HIV is common to all groups of individuals on treatment and is comparable to that in other chronic diseases like diabetes, hypertension and heart disease. (theseoultimes.com)
This case illustrates the importance of taking the time to have effective communication with a patient and his or her family to recognize the reasons for nonadherence and understand their beliefs, set realistic treatment goals, provide simple measures for improvements and to establish a routine, and allow shared decision-making to promote better adherence and achieve optimal asthma control. (medpagetoday.com)
In HIV treatment, ART adherence represents one element of the wider HIV care continuum. (nih.gov)
Notably, proper treatment adherence is essential for successful treatment outcome [1, 2]. (ersjournals.com)
While persistence may be greater with a treatment requiring less frequent administration, there are obviously a whole host of other factors to consider when choosing the right osteoporosis drug for an individual patient, Dr. Ye said, but that all rheumatologists should be asking patients about and counselling on adherence and reviewing expired prescriptions. (hcplive.com)
I make a point of explaining how important adherence and persistence are with osteoporosis medications the first time that I prescribe them to a patient.I also make it clear that although the prescription expires in 1 year, I intend for the treatment to be long term and that they should get renewals from myself or their family doctor," she said. (hcplive.com)
Discrimination can result in sub-optimal care through deficient communication and preventing treatment adherence. (latinamericanpost.com)
Limitations of the study include suboptimal adherence to treatment strategies and short-term 30-day follow-up. (the-hospitalist.org)
To what extent are patients with uncontrolled asthma switched to biologics due to poor treatment adherence vs lack of maintenance therapy efficacy? (empr.com)
As you can imagine, patient adherence to these treatment options is a significant challenge. (medgadget.com)
Identifying and addressing psychosocial barriers to care is a key element of ensuring long-term adherence to treatment. (aafp.org)
Drug resistance can arise from poor ART adherence and suboptimal viral suppression rates, driven by weak health systems and treatment interruptions. (advfn.com)
BACKGROUND AND AIM: Current treatment for irritable bowel syndrome (IBS) is suboptimal. (medscape.com)
The objective of this exploratory study was to identify factors influencing HCWs' adherence to policies for routine tuberculin skin tests (TSTs) and treatment of latent TB infection (LTBI). (cdc.gov)
Participants were segmented by adherence to TST or LTBI treatment policies. (cdc.gov)
Received tuberculin find and recruit HCWs based on adherence or non- skin test on time adherence to TSTs and LTBI treatment. (cdc.gov)

There is evidence for racial disparity in adherence to antihypertensive medication, however, possibly due to "affordability of medicines, personal beliefs, anticipated adverse effects, and health literacy that disproportionally affect blacks," Dr. Fiscella said, adding "There is evidence from previous studies that access barriers and financial and interpersonal communication barriers affect the ability of black patients to get medical care or to take their medication as prescribed. (medscape.com)

STRs that reduce pill burden to as little as 1 pill taken once daily have been associated with improved adherence, reduced hospitalizations, and improved viral suppression. (pharmacytimes.com)
Sub-optimal adherence may reduce the effectiveness of the regimen by allowing viral replication and the emergence of drug resistant strains. (who.int)

Adherence to clinical guidelines in practice is often suboptimal and controversial. (ajmc.com)
Measuring adherence to clinical guidelines using mobile health (mHealth) technologies when form field validation is enforced or turned on could potentially be viewed as skewing the dataset, leading to 100% adherence to the clinical rule base. (lu.se)
With form field validation on adherence to the clinical guidelines is enforced which minimises incomplete assessment and the potential for suboptimal clinical decisions that could adversely affect patient care. (lu.se)

The use of fixed drug combinations may enhance patient adherence and may reduce the risk of inappropriate monotherapy, and it may prevent the development of secondary drug resistance. (cdc.gov)
Regimen simplification advances patient care by way of better adherence, lower resistance development, higher persistency leading to long term success, less hospitalization and lower cost of care. (theseoultimes.com)
Poor adherence is defined as failure to take treatments as agreed upon between the patient and clinician. (medpagetoday.com)
There is no "typical" nonadherent patient, so identifying medication adherence can be challenging. (medpagetoday.com)
2021) High HCV Cure Rates among People Who Inject Drugs and have Suboptimal Adherence: A Patient-Centered Approach to HCV Models of Care. (clemson.edu)
They identified 40 English language observational studies published up to September 2018 that examined patient adherence and/or persistence to parenteral osteoporosis treatments. (hcplive.com)
3 , 4 The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2019 management cycle recommends an assessment of inhaler technique and adherence and of non-pharmacological approaches such as pulmonary rehabilitation and patient education. (dovepress.com)
There is a strong relationship between adherence and how much a patient costs the system," Dr Edelman said. (ahdbonline.com)

Persistence and adherence to parenteral osteoporosis therapies are suboptimal and worsen with time, a study finds. (hcplive.com)

Decreasing pill burden by simplifying the ART regimen is one method used to promote ART adherence," the authors wrote. (pharmacytimes.com)

Persistence and adherence to parenteral treatments for osteoporosis varies between therapies, but, overall, rates are suboptimal and decrease over time, the first systematic review and meta-analysis using real-world data to look at the issue has found. (hcplive.com)
A similar relationship has been seen with oral therapies, such as bisphosphonates, where adherence and persistence has been found to be greater for those requiring weekly or monthly administration compared to daily dosing. (hcplive.com)
Persistence rates with teriparatide were 10-87% (median 55%) at one year and 10-69% (median 29.5%) at two years, and adherence rates were 21-89% (median 53%) at one year and 37-68% (median 40%) at two years. (hcplive.com)
Persistence rates for ibandronate at one year were 31-58% (median 47.5%) and 13-35% (median 25%) at 2 years, and adherence rates were 21-72% (median 47.3%) and 15-58% (median 36.5%) respectively. (hcplive.com)
When you look at study after study on adherence and persistence, about 25% to 30% of patients are still on that medication after 1 year, and even lower after 2 years, whether you are talking about an injectable agent, a basal insulin, or GLP 1 agent, or even oral DPP 4 medication. (ahdbonline.com)

Careful attention should be paid to measures designed to foster adherence and to ensure that patients take the drugs as prescribed. (cdc.gov)
Litwin A. (2021) Rates of Perfect Self-Reported Adherence to Direct-Acting Antiviral Therapy and Its Correlates Among People Who Inject Drugs on Opioid Agonist Therapy: The PREVAIL Study. (clemson.edu)

Dr Satish said that, Adherence is a complicated issue regardless of the nature of the disease and is equally problematic in resource- poor and rich settings. (theseoultimes.com)
Then again association between poor-adherence and ARV resistance is well documented. (theseoultimes.com)
7% has not changed in the past 10 years, Dr Edelman said, despite advances in therapies and new delivery technologies, which is largely attributed to poor medication adherence. (ahdbonline.com)

2,3 This is not dissimilar to the approximate rates of adherence of 50% seen in other chronic conditions for which long-term medications are prescribed. (medpagetoday.com)
Cancer survivors and control subjects had similar rates of PA adherence. (cdc.gov)
Therefore, determining the rates of PA adherence and correlates to such adherence is important. (cdc.gov)
The other major advantage is high compliance - by creating a product experience that is genuinely engaging for patients to use, we have observed adherence rates in our trials that are almost double those observed for patching. (medgadget.com)

Medication adherence is typically defined by the proportion of days covered and medication possession ratio (MPR). (ahdbonline.com)

In one study of pharmacy database medication refills of a combination of an inhaled corticosteroid and a long-acting beta-agonist in a single device, approximately 22% adherence over the course of a year was found. (medpagetoday.com)
2 In the setting of a prospective asthma cohort study in which adherence was calculated from electronic health records and pharmacy claims data, the most significant reduction in risk of exacerbation was seen in patients whose adherence exceeded 75% of that prescribed. (medpagetoday.com)
This study describes adherence to PA recommendations among cancer survivors compared with control subjects without cancer and the association between survivor adherence to PA guidelines and demographic, psychosocial, and clinical factors, as well as health-related quality of life (HRQOL). (cdc.gov)
This is the first cross-sectional study which aims to examine associations between beliefs about medication and non-adherence in RA patients, taking potential psychological confounders into account in the data-analysis. (nivel.nl)
The purpose of the study is to examine disparities in adjuvant endocrine therapy (AET) adherence and discontinuation among Texas Medicaid-insured early-stage breast cancer patients. (ahrq.gov)
If the broader environment where hand individual was interested in joining the Adherence to proper hand hygiene hygiene takes place and for explaining focus group, the study investigator in- practices is an effective measure to re- the reasons and meanings for the hand vited her/him for the discussion the duce the risk of health-care associated hygiene behaviours. (who.int)

however, results were consistent across different adherence levels. (cun.es)

Racial differences in long-term adjuvant endocrine therapy adherence and mortality among Medicaid-insured breast cancer patients in Texas: findings from TCR-Medicaid linked data. (ahrq.gov)
The purpose of this article was to determine whether the mortality disparities could be explained by racial/ethnic differences in long-term adherence to adjuvant endocrine therapy (AET). (ahrq.gov)
The investigators concluded that long-term adherence in the Medicaid population was suboptimal and racial/ethnic differences in AET adherence may partially explain disparities in mortality. (ahrq.gov)
Racial and geographic disparities in adherence and discontinuation to adjuvant endocrine therapy in Texas Medicaid-insured patients with breast cancer. (ahrq.gov)
[ 3 ] He and Dr. Holt believe that "elimination of racial disparity in blood pressure control is an attainable goal, provided sufficient resources are available to discover and address adherence barriers. (medscape.com)

We examined PA adherence among 8,655 cancer survivors and 144,213 control subjects aged 45-64 years who were respondents to the 2009 Behavior Risk Factor Surveillance System survey. (cdc.gov)
The development of a fixed dose combination aims to reduce the number of daily tablets, and therefore enhance adherence to therapy and thereby minimizing the risk of emergence of resistance. (who.int)
Methods: A cluster, randomized controlled design was used to evaluate the efficacy of a web-based audit and feedback intervention intended to increase risk perception, reduce barriers to PPE use, and ultimately improve adherence to recommended PPE. (cdc.gov)

The overall conclusion is that there has been a tight adherence to traditional methods and practices, some of which are suboptimal. (ed.gov)

This 14-year-old girl with a long history of well-controlled asthma experiences a breakthrough cough and declining lung function as a result of non-adherence. (medpagetoday.com)

To improve adherence, counseling and education are important. (ersjournals.com)
Of the BMQ constructs associated with non-adherence, increasing necessity beliefs about medication in clinical practice might be most worthwhile to improve medication adherence in RA patients. (nivel.nl)

Suboptimal adherence predisposes to drug resistance. (theseoultimes.com)
Understanding patients' perspectives on drug adherence is essential for identification of barriers to therapy. (diabetesjournals.org)
4 Conversely, every 1% improvement in drug utilization is associated with approximately a 1% drop in the cost of care, and every 1% increase in adherence is linked to a 0.1% decrease in HbA 1c levels. (ahdbonline.com)

Research applications primarily addressing aspects of the HIV care continuum other than ART adherence, such as HIV diagnosis and care engagement, may consider the priorities identified in PA-14-130 and PA-14-132 , "Accelerating Improvements in the HIV Care Continuum. (nih.gov)
CPC programs are open to clinicians in all specialties, at all stages of their careers, and is of special utility for primary care clinicians, diabetes educators, health coaches and others who work with patients whose lifestyle choices and adherence can have significant health impacts. (guidestar.org)

He further explained to Citizen News Service (CNS): "Understanding these factors can increase providers attention to adherence. (theseoultimes.com)
Adherence can be affected by numerous factors, both related to the patients-such as knowledge and understanding of their disease process, lifestyle, and available support and resources-and the providers, who may have limited time and resources for educating patients. (medpagetoday.com)

Suboptimal adherence to medical therapy in patients undergoing lower limb angioplasty. (annals.edu.sg)
If there is evidence of a slow or suboptimal response, therapy should be prolonged as judged on a case by case basis. (cdc.gov)
Adherence to insulin therapy is often suboptimal. (diabetesjournals.org)
OBJECTIVE To test cognitive behavioral therapy for adherence and depression (CBT-AD) in type 2 diabetes. (harvard.edu)

OBJECTIVE To assess the validity of self-report measures of diabetes medication adherence and evaluate the effect of depression on the validity of these reports. (harvard.edu)

2 Lack of adherence in adult asthmatics is associated with increased hospitalizations and mortality. (medpagetoday.com)

Yet, adherence to the peak CVD-prevention guidelines in Australia remains suboptimal (6). (apna.asn.au)

Demographic factors, such as age, type of health plan, and number of hospitalizations, did not correlate to medication adherence, although male gender tended to correlate to better adherence, the authors noted. (pharmacytimes.com)

A team approach is needed to optimally maximize adherence. (theseoultimes.com)

We sought to identify correlates of adherence to PA and to determine whether PA adherence is associated with health-related quality of life (HRQOL) among cancer survivors. (cdc.gov)

We used multinomial logistic regression to assess associations between PA adherence and demographic, psychosocial, and clinical factors, and multivariable linear regression to assess the relationship between PA adherence and HRQOL of cancer survivors. (cdc.gov)
Associations between beliefs and non-adherence, and the influence of demographical, clinical and psychological factors (symptoms of anxiety/depression, illness cognitions, self-efficacy) were assessed using logistic regression. (nivel.nl)

Yet both have sub-optimal adherence with implications for their own health as well as onward transmission. (ucl.ac.uk)
Health and social service provision, if it is to be effective, needs to address these different youth profiles to ensure optimal adherence, development and wellbeing throughout the life course. (ucl.ac.uk)

Instability in household configuration was an important reason for suboptimal TPT provision. (who.int)

Anatomy1

Diseases2

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Psychiatry and Psychology2

Phenomena and Processes3

Anthropology, Education, Sociology and Social Phenomena2

Information Science1

Health Care8

Outcomes10

Regimens9

Interventions6

Issue of adherence2

Barriers to adherence2

Medication non-adherence3

Patients with type 2 diabet2

Treatment23

Antihypertensive medication1

Viral2

Clinical guidelines3

Patient8

Worsen1

Regimen1

Persistence5

Drugs2

Poor3

Rates4

Typically1

Study6

Consistent1

Racial5

Risk3

Conclusion1

Asthma1

Improve2

Drug3

Care2

Understanding2

Therapy4

Evaluate1

Lack1

Guidelines1

Hospitalizations1

Approach1

Quality of l1

Factors2

Health2

Important1