Subarachnoid hemorrhage vasospasm in patients. Medical search. Frequent questions

Spontaneous subarachnoid hemorrhage (SAH) affects individuals with a mean age of 55 years and accounts for 5% of stroke cases. (nature.com)
8. Sung W, Arnaldo B, Sergio C, Juliana S, Michel F. Terson's syndrome as a prognostic factor for mortality of spontaneous subarachnoid haemorrhage. (cns.org)
I am interested in the study of the radiological characteristics and temporal profile of edema/ tissue injury in the perihematomal area around spontaneous intracerebral hemorrhage. (stanford.edu)
Background For endovascular rescue therapy (ERT) of cerebral vasospasm (CVS) due to spontaneous subarachnoid haemorrhage (sSAH), non-compliant (NCB) and compliant (CB) balloons are used with both balloon types bearing the risk of vessel injury due to specific mechanical properties. (bmj.com)
Cerebral vasospasm (CVS) after spontaneous subarachnoid haemorrhage (sSAH) can result in delayed cerebral ischaemia (DCI) and CVS-associated infarction, both worsening patients outcome. (bmj.com)
Delayed cerebral ischemia (DCI) and cerebral vasospasm (CV) are severe complications of spontaneous subarachnoid hemorrhage (SAH) contributing to an inferior outcome. (thejns.org)

Of those patients who are able to reach neurosurgical centers and have their aneurysm treated, an estimated 14% either die or sustain significant morbidity as a result of cerebral vasospasm. (medscape.com)
Several factors have been associated with clinical deterioration, including aneurysm rebleeding, hydrocephalus, delayed cerebral ischaemia from vasospasm, and seizures. (bmj.com)
A congenital intracranial saccular or berry aneurysm is the cause in about 85% of patients. (msdmanuals.com)
Aneurysmal subarachnoid hemorrhage (aSAH) is a sudden, life-threatening bleeding occurring in the subarachnoid space, caused by the rupture of an aneurysm. (biospace.com)
A CT angiogram was completed and the neurosurgeon, who does both endovascular coiling as well as open clipping favors open craniotomy for this patient given the geometry of the aneurysm (wide neck) as well as proximity to nearby vessels. (snacc.org)
How do you decide whether to allow patient emergence after aneurysm clipping? (snacc.org)
There are interactions between other organ systems (for example the heart and lungs) that may complicate the care of a ruptured cerebral aneurysm patient and need consideration. (snacc.org)
Delayed cerebral ischemia can manifest after a successful operation for securing the aneurysm and patients at risk require monitoring for this complication in the post-operative period. (snacc.org)
We describe a 40-year-old woman who developed vasospasm 8 days after surgery for clipping an aneurysm, following a large subarachnoid hemorrhage. (tau.ac.il)
METHODS: This retrospective study includes 250 patients presented to a teaching hospital with SAH and underwent aneurysm clipping during a 10-year period. (eastjmed.org)
There were no statistically significant differences in the baseline characteristics between patients undergoing EC versus NC for either ruptured or unruptured aneurysm groups. (journaltocs.ac.uk)
To investigate the role of DNA methylation in DCI risk, we conducted an epigenome-wide association study (EWAS) in 68 patients followed up to 1 year after the initial aneurysm rupture. (biomedcentral.com)
Delayed cerebral ischemia (DCI) is a common secondary complication among aneurysmal subarachnoid hemorrhage (aSAH) patients who survived the initial bleeding caused by ruptured aneurysm. (biomedcentral.com)

The (ICE) component comprises a catheter with platinum sensors that, when inserted into the brain allows for recording directly from the cerebral cortex of patients with acute brain injury. (wikipedia.org)
Bedside Optical Coherence Tomography for Terson's Syndrome screening in Acute Subarachnoid Hemorrhage: A pilot study. (cns.org)
Our goal was to evaluate the feasibility and potential role of bedside optical coherence tomography (OCT) in Terson's Syndrome (TS) in patients with acute subarachnoid hemorrhage (aSAH) and its potential role in blindness prevention. (cns.org)
Open label pilot study: 31 patients with angiographic diagnosis of aSAH were first screened for TS with dilated fundoscopy and then with OCT in the acute phase and at 6-week follow-up visits. (cns.org)
OCT identified 7 patients (22.6% incidence of TS in our aSAH sample: 7 in the acute phase, a large retinal detachment was initially missed by fundoscopy and diagnosed by OCT in follow up clinic). (cns.org)
Her primary focus is the clinical care of critically ill patients in the neurological and other intensive care units and patients with acute stroke and TIA in the inpatient stroke unit. (stanford.edu)
I care for neurologically critically ill patients in the intensive care unit and patients with acute stroke and TIA in the inpatient stroke unit. (stanford.edu)
ZOMIG Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults and pediatric patients 12 years of age and older. (nih.gov)
METHODS: We retrospectively identified 27 patients with acute subarachnoid hemorrhage who had undergone CTA/PCT, DSA, and transcranial Doppler (TCD) ultrasonography within a time interval of 12 hours of one another. (keyopinionleaders.com)
BACKGROUND AND PURPOSE: To test the safety and recanalization efficacy of intra-arterial local delivery of plasminogen activators in acute ischemic stroke, a randomized trial of recombinant pro-urokinase (rpro-UK) versus placebo was undertaken in patients with angiographically documented proximal middle cerebral artery occlusion. (keyopinionleaders.com)
A 77-year-old man presented with an acute subarachnoid hemorrhage of the posterior fossa. (keyopinionleaders.com)
Neuroimaging plays a vital role in the workup of acute stroke by providing information essential to accurately triage patients, expedite clinical decision making with regards to treatment, and improve outcomes in patients presenting with acute stroke. (medscape.com)

Cerebral vasospasm leading to delayed cerebral ischemia (DCI) continues to be a major complication and source of morbidity in cases of aSAH. (medscape.com)
nimodipine is currently recommended as first-line medical treatment for preventing post-aSAH cerebral vasospasm. (medscape.com)
There are many postulated theories as to the etiology of cerebral vasospasm after aSAH, but the mechanisms ultimately responsible for vasospasm are still incompletely understood. (medscape.com)
[ 5 ] has been found to be elevated in cerebrospinal fluid (CSF) after aSAH and may play a role in cerebral vasospasm and DCI. (medscape.com)
Cerebral vasospasm has been estimated to occur in 12-30% of the approximately 30,000 North American patients who experience aSAH each year. (medscape.com)
[ 7 , 8 ] It has been estimated that close to 50% of patients suffering from aSAH die before reaching medical care. (medscape.com)
There are certain patient characteristics that may increase the likelihood of vasospasm occurring in a patient with aSAH. (medscape.com)
Some of the strongest predictors of vasospasm relate to the severity of the aSAH as graded according to several well-accepted classification systems. (medscape.com)
On the Fisher Scale, the thickness of the aSAH clot and the presence of intraventricular hemorrhage (IVH) are strong predictors of vasospasm. (medscape.com)
Various imaging modalities are employed to diagnose cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH). (medscape.com)
Aneurysmal subarachnoid hemorrhage (aSAH) is a serious condition with high mortality and a high permanent disability rate. (nature.com)
In this study, we examined the association of clinical outcome with the Controlling Nutritional Status (CONUT) score during hospitalization in aSAH patients. (nature.com)
Patients transported to the emergency room for aSAH and diagnosed with World Federation of Neurosurgical Societies (WFNS) grade III and IV aSAH between April 2004 and March 2021 were enrolled. (nature.com)
127 patients diagnosed with WFNS grade III and IV aSAH were analyzed. (nature.com)
These findings indicate that CONUT score during hospitalization may be a useful daily marker for predicting poor outcomes in aSAH patients. (nature.com)
The social and economic losses of patients with aSAH in the event of death or inability to return to society are therefore substantial 3 . (nature.com)
4 at admission independently predicted patients' functional outcome status at 3 months after aSAH 7 . (nature.com)
However, it is unclear whether the CONUT score during hospitalization influences the functional outcomes of aSAH patients. (nature.com)
Here, we retrospectively analyzed the relationship between clinical outcomes and the CONUT score in aSAH patients during hospitalization. (nature.com)
In Japan, PIVLAZ™ (clazosentan) 150 mg, is indicated for the prevention of cerebral vasospasm, vasospasm-related cerebral infarction and cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage (aSAH) securing. (biospace.com)
Idorsia Ltd (SIX: IDIA) and Idorsia Pharmaceuticals Japan today announced that PIVLAZ™ (clazosentan) is now available to physicians in Japan to start treating aSAH patients. (biospace.com)
2 Clot hemolysis and the release of vasoconstricting agents can contribute to cerebral vasospasm, which typically begins approximately 3 days after aSAH onset, peaks in severity at days 8-11, and resolves by day 21. (biospace.com)
7 If untreated, cerebral vasospasm can be a key factor of morbidity and mortality in patients with aSAH. (biospace.com)
2 Cerebral vasospasm may lead to delayed ischemic neurological deficit (DIND) in 20-50% of aSAH patients, and half of the patients with severe vasospasm develop cerebral infarction. (biospace.com)
The program demonstrated that clazosentan, a selective endothelin A (ET A ) receptor antagonist, significantly reduced the combined incidence of vasospasm-related morbidity and all-cause mortality post-aSAH with no unexpected safety findings 1 . (biospace.com)
Two prospective, multicenter, double-blind, randomized, placebo-controlled, pivotal Phase 3 studies assessing the efficacy and safety of clazosentan in reducing vasospasm-related morbidity and all-cause mortality events in adult Japanese patients post-aSAH, were conducted in parallel in 57 neuro surgical centers in Japan. (biospace.com)
Patients were randomized 1:1 to receive continuous infusion of either 10 mg/hr of clazosentan or placebo within 48 hours of the onset of aSAH for up to a cumulative maximum of 15 days after aSAH. (biospace.com)
Delayed cerebral ischemia (DCI) is a common secondary complication and an important cause of disability and mortality among patients who survive aneurysmal subarachnoid hemorrhage (aSAH). (biomedcentral.com)

The knockout mice developed less severe vasospasm and had better neurological outcomes than mice with MMP-9 present. (wustl.edu)
To avoid further hemodynamic compromise, we used a new monitor of cardiac function to measure intravascular volumes and quantify pulmonary edema to help titrate the fluid management of a patient in severe vasospasm. (tau.ac.il)

More invasive means of treating vasospasm depend on the utilization of cerebral angiography and include intra-arterial vasodilator administration and balloon angioplasty. (medscape.com)
Materials and Methods We retrospectively reviewed medical records and radiological images of 7 patients who developed delayed vasospasm following subarachnoid hemorrhage and showed recurrence after initial angioplasty using intra-arterial vasodilator infusion from 2014 to 2017 at our institution. (bmj.com)
Neurological improvements were noted in 6 (86%) patients after the procedures which include subsequent intra-arterial vasodilator infusion. (bmj.com)
In the presented case, a young female patient with fulminant refractory DCI and CV, despite induced hypertension and nimodipine application, was treated with three-vessel continuous intra-arterial infusion and additional repetitive angioplasty of the basilar and middle cerebral arteries using a stent retriever, leading to a good clinical outcome. (thejns.org)

A metaanalysis, investigating a total of 652 included patients revealed a significant reduction of delayed neurological deficits, a significant increase of outcome and a significant decrease of mortality in the treatment group. (nih.gov)
As a consequence of the significant neurologic morbidity or mortality stemming from posthemorrhagic vasospasm, a great deal of interest and research has been focused on understanding its physiologic mechanism and developing effective preventive and therapeutic measures. (medscape.com)
The 30-day and 6-month mortality rate is 39% and 49%, respectively, and only 23% of patients have a favorable outcome, as evaluated using a modified Rankin scale (mRS) score of 0-2 2 . (nature.com)
Conclusions Early worsening after SAH occurs in 35% of patients, is predicted by clot burden and is associated with mortality and poor functional outcome at 1 year. (bmj.com)
Subarachnoid haemorrhage (SAH) is associated with a high mortality and morbidity. (bmj.com)
Introduction: Vasospasm accounts for a large fraction of the morbidity and mortality burden in patients sustaining subarachnoid hemorrhage (SAH). (houstonmethodist.org)
Mortality was 10.3% and vasospasm-related morbidity and mortality occurred in 6% and 6.8% of the patients, respectively. (eastjmed.org)

Conclusion Mechanical angioplasty using stent-retrievers for the delayed symptomatic vasospasm in the subarachnoid hemorrhage patients can be a feasible option especially for the recurred cases after chemical only angioplasty. (bmj.com)
Possible overlap between reversible cerebral vasoconstriction syndrome and symptomatic vasospasm after aneurysmal subarachnoid hemorrhage. (saintluc.be)

reported in a prospective study of 58 SAH patients that a negative energy balance during the first 7 days after SAH correlated with the number of infectious complications 10 . (nature.com)
These researchers also showed in a prospective observational study of 229 SAH patients that a negative nitrogen balance during the first 14 post-bleed days is a risk factor for infectious complications and is associated with poor outcomes (mRS ≥ 4) at 3 months 11 . (nature.com)
1 The detrimental effect of medical complications in the first 2 weeks after haemorrhage on long term outcome has been extensively studied. (bmj.com)
INTRODUCTION: This study investigates effects of early surgery in aneurysmal subarachnoid hemorrhage (SAH) on outcome and postoperative complications. (eastjmed.org)
In addition to its proven efficacy in patients with late PD, the EARLYSTIM trial not only demonstrated the efficacy of DBS in patients with early motor complications but also showed that it did not lose its therapeutic efficacy as the years passed by. (neurologyindia.com)

However, the etiology of cerebral vasospasm remains poorly understood. (medscape.com)
Other uses include refractory status epilepticus, cerebral vasospasm after subarachnoid hemorrhage (SAH), comatose survivors of cardiac arrest, and patients with cerebral edema and elevated ICP from any etiology other than TBI. (anesthesiageneral.com)

Her research focuses on the study of intracerebral hemorrhage using brain imaging with CT and MRI. (stanford.edu)
She is the Stanford prinicipal investigator for several clinical trials in intracerebral hemorrhage and large hemispheric infarction. (stanford.edu)

Digital subtraction angiography (DSA) has been regarded as the gold standard for diagnosis and treatment of vasospasm, but outcome benefit for the treatment of angiographic vasospasm has not been demonstrated, leading to the addition of more qualitative blood flow tools. (medscape.com)
Vasospasm after subarachnoid hemorrhage: utility of perfusion CT and CT angiography on diagnosis and management. (keyopinionleaders.com)
PURPOSE: To evaluate the utility of perfusion CT (PCT) combined with CT angiography (CTA) for the diagnosis and management of vasospasm, by using conventional digital subtraction angiography (DSA) as the gold standard. (keyopinionleaders.com)
Patients admitted with SAH should be promptly evaluated and undergo angiography. (eastjmed.org)
Although the first such report in the literature, Gunasekaran noted that "with new advances in neuroimaging like cerebral angiography and increased use of vasoactive substances, physicians may encounter a growing number of patients with RCVS spectrum. (medscape.com)

Cerebral arterial vasospasm continues to be a major complication of aneurysmal SAH. (biomedcentral.com)

For this reason, routine surveillance imaging studies are carried out to supplement the neurologic examination with the aim of diagnosing vasospasm before the onset of delayed cerebral ischemia (DCI). (medscape.com)
Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. (medscape.com)
Secondary vasospasm (causing focal brain ischemia), meningismus, seizures, and hydrocephalus (causing persistent headache and obtundation) are common. (msdmanuals.com)

Factors predicting relapse of nonfunctioning pituitary macroadenomas after neurosurgery: a study of 142 patients. (saintluc.be)

TCD is a noninvasive modality that extrapolates the likelihood of vasospasm on the basis of selective intracranial arterial blood flow velocity ratios, trends, and relations. (medscape.com)

[ 9 , 10 ] These are the primary determinants of the Modified Fisher Scale, with a higher Fisher score being directly correlated with the risk of vasospasm. (medscape.com)
Brain edema is maximal and risk of vasospasm and subsequent infarction (called angry brain) is highest between 72 hours and 10 days. (msdmanuals.com)

Both the Fisher Scale and the Hunt-Hess grading system have been shown to correlate with the incidence of vasospasm. (medscape.com)
Using their mouse model of subarachnoid hemorrhage, they found that the drug reduced the incidence of vasospasm and improved outcomes. (wustl.edu)
If the trial is successful, the team will conduct a phase II study to look not only at safety and MMP-9 levels but also at whether the incidence of vasospasm is reduced in patients receiving minocycline. (wustl.edu)
If we start to see that minocycline is safe and reduces MMP-9 levels and we have signs in phase II that the incidence of vasospasm is lower, then we will design a multicenter phase III trial to look at the long-term neurologic outcomes of minocycline treatment," Zipfel says. (wustl.edu)

Furthermore, 20-40% of patients with ischemic infarction may develop hemorrhagic transformation within one week after ictus. (medscape.com)

What is the time frame that leads to the best patient outcome for securing intracranial aneurysms? (snacc.org)
whereas among 180 patients treated for unruptured aneurysms, 140 (77.8%) underwent EC and 40 (22.2%) underwent NC. (journaltocs.ac.uk)
The outcomes were statistically comparable between EC and NC for both ruptured and unruptured IA, except for a lower incidence of ischemic stroke in patients undergoing EC for ruptured aneurysms (OR 0.12, 95% CI 0.02 to 0.84).ConclusionsMost pregnant and postpartum patients are treated with EC for both ruptured and unruptured IA. (journaltocs.ac.uk)

In addition, she sees patients with stroke and neurovascular diseases in her stroke clinic as well as patients discharged from the neurological ICU in the Outcomes clinic. (stanford.edu)
Her main interests are in brain hemorrhage, unusual and rare causes of stroke, cerebral venous thrombosis, anticoagulation management after strokes and use of technology for improving outcomes in the neurological ICU. (stanford.edu)
These guidelines do not explicitly include patients with stroke, however. (keyopinionleaders.com)
Aug. 27, 2022 - A research center in Tübingen, Germany is looking for patients with post-stroke hand paralysis to further study a rehabilitation training approach they recently published involving a brain-computer interface. (neuromodulation.com)
Increasing evidence has shown that statin use is associated with a significant beneficial effect in patients with ischemic stroke. (neurologyindia.com)
Furthermore, good adherence is associated with a better clinical outcome, and statin withdrawal is associated with a poor functional outcome in patients with ischemic stroke. (neurologyindia.com)
However, there are concerns regarding the adverse effects associated with statin use in ischemic stroke such as intracranial hemorrhage. (neurologyindia.com)
[ 6 , 7 ] Differentiating between these different types of stroke is an essential part of the initial workup of these patients because the subsequent management of each patient is vastly different. (medscape.com)
The diagnosis of FMD should be considered in any young individual presenting with a stroke or subarachnoid hemorrhage. (medscape.com)

Guidelines have recommended these modalities as reasonable for treatment of symptomatic patients who are not responding to hypertensive therapy. (medscape.com)

If a patient has no response to zolmitriptan treatment for the first migraine attack, reconsider the diagnosis of migraine before zolmitriptan is administered to treat any subsequent attacks. (nih.gov)
Thirty-one patients with catheters but without ventriculitis were selected as matched controls based on age, sex, and primary diagnosis. (stanford.edu)
Inclusion criteria included studies that involved more than 20 patients with a physician confirmed diagnosis of PD and a follow-up of greater than or equal to at least 12 months. (neurologyindia.com)
After ruling out the common causes, including subarachnoid hemorrhage and cerebral vasculitis , neurologists should consider RCVS in the differential diagnosis of thunderclap headaches in those with a history of ingestion of vasoactive substances like hot chili peppers," he said. (medscape.com)
Taking a thorough history including dietary habits plays a very important role in diagnosis and management of these patients. (medscape.com)

Outcomes of transsphenoidal surgery in prolactinomas: improvement of hormonal control in dopamine agonist-resistant patients. (saintluc.be)
Our long-term goal is to improve outcomes after subarachnoid hemorrhage. (wustl.edu)
What tactics should be employed during temporary clipping to improve patient outcomes? (snacc.org)
Methods: The literature was reviewed for studies investigating the role of PDGF in the pathogenesis of SAH-related vasospasm and efficacy of pharmacological interventions targeting the PDGF pathway in ameliorating the same and improving clinical outcomes. (houstonmethodist.org)
Conclusions: Four unique endotypes of hospitalized patients with COVID-19 were identified, which segregated patients based on inflammatory markers, infectious markers, evidence of end-organ dysfunction, comorbidities, and outcomes. (stanford.edu)
84.8% of patients had favorable outcomes and 15.2% of patients had poor outcomes. (eastjmed.org)
Aug. 24, 2022 - A team of co-authors questioned if there may be multiple targets for a common network in publishing an analysis of brain connectivity patterns and outcomes in 10 patients who had received stimulation to different brain targets in order to treat therapy-resistant self-injurious behavior. (neuromodulation.com)

Normal pressure hydrocephalus in a patient with myotonic dystrophy: case report with a 10-year follow-up. (saintluc.be)

In conclusion, there is strong evidence that cisternal or ventricular lavage alone and in combination with kinetic therapy lead to a reduction of cerebral vasospasm and better outcome in patients suffering from subarachnoid hemorrhage. (nih.gov)
All of these factors and the fact that there is no good evidence from randomized, controlled clinical trials that pentobarbital coma improves outcome in patients with various neurological pathologies have led many practitioners to consider this therapy as the last resort when other treatments have been exhausted. (anesthesiageneral.com)

Patients with refractory epilepsy treated using a modified multiple subpial transection technique. (saintluc.be)
Epileptic discharges in a mammillary body of a patient with refractory epilepsy. (saintluc.be)
Deep brain stimulation (DBS) has become an established therapeutic tool for treating patients with Parkinson's disease (PD) who have troublesome motor fluctuations and dyskinesias refractory to best medical therapy. (neurologyindia.com)
For instance, patients with refractory ICP elevations will have to be treated as long as the abnormal intracranial compliance is present, which may be for several days. (anesthesiageneral.com)
As such, pentobarbital coma should be used only in patients with elevated ICP refractory to medical and surgical therapy and status epilepticus refractory to other treatments including propofol and midazolam drips. (anesthesiageneral.com)
Barbiturate coma for severe, refractory vasospasm following subarachnoid hemorrhage. (anesthesiageneral.com)

Follow-up images showed no significant recurrence of vasospasm in the vessels dilated by the stentrievers. (bmj.com)

The causes of intractable fever in severe traumatic brain injury (TBI) patients can be diverse. (neurologyindia.com)
The most common application has been to lower elevated intracranial pressure (ICP) in patients with severe traumatic brain injury (TBI). (anesthesiageneral.com)

In fact, many treated patients will need extra cardiovascular support including vasopressors and pulmonary artery catheter insertion to monitor cardiac function and volume status. (anesthesiageneral.com)

The results with clazosentan are very impressive and represent a ground-breaking therapeutic advancement in the prevention of cerebral vasospasm. (biospace.com)
Conclusion: Treatments with statins, serine protease inhibitors, and small molecular pathway inhibitors have demonstrated varying degrees of efficacy in prevention of cerebral vasospasm, which is improved with earlier institution. (houstonmethodist.org)
BACKGROUND AND PURPOSE: Current US guideline statements regarding primary and secondary cardiovascular risk prediction and prevention use absolute risk estimates to identify patients who are at high risk for vascular disease events and who may benefit from specific preventive interventions. (keyopinionleaders.com)

CT perfusion studies have been shown to be more useful for diagnosing vasospasm in patients with delayed neurologic deficits than they are in asymptomatic patients. (medscape.com)

The patient required HHH therapy with a very high blood pressure to optimize her clinical neurologic status, but she started to develop pulmonary edema resulting from this therapy. (tau.ac.il)

Methods We identified risk factors for worsening on the Hunt-Hess grading scale within the first 24 h after admission in 609 consecutively admitted aneurysmal SAH patients. (bmj.com)
Methods Twelve patients with utilisation of either NCB or CB for CVS were retrospectively analysed for clinical characteristics, ERT, functional outcome after 3 months and RFU. (bmj.com)
Methods: Consensus clustering (using the ensemble method) of patient age and laboratory values during admission identified endotypes. (stanford.edu)

Fever in severe TBI patients is not an uncommon phenomenon, but when intractable with negative fever workup, a central cause should be considered. (neurologyindia.com)

Can ultrasound predict nerve injury following posterior tibial nerve block in diabetic patients with peripheral neuropathy? (asra.com)
Because laminectomy has been shown to predispose patients to kyphosis, laminoplasty and hemilaminectomy are the most widely used approaches to preserve the posterior tension band (PTB). (thejns.org)
Doctors detected multifocal luminal narrowing in his left supraclinoid internal carotid artery, M1 segment of bilateral middle cerebral arteries, and P1 segments of bilateral posterior cerebral arteries - a finding consistent with vasospasm. (medscape.com)

All patients received hypervolemic hemodilution therapy aiming for a hematocrit of 33-38%, 10-12 mmHg central venous pressure (or 15-18 mmHg pulmonary wedge pressure), and 160-200 mmHg systolic arterial pressure during the risk period for vasospasm. (biomedcentral.com)

This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery. (stanford.edu)
Subarachnoid hemorrhage patients who require SAH surgery and post-operative routine treatment. (who.int)

The combined application demonstrated reduced delayed neurological deficits, reduced vasospasm and better outcome in two studies for the treatment group. (nih.gov)
New neurologic deficits caused by vasospasm may be difficult to recognize in patients who are already severely debilitated. (medscape.com)

Aug. 31, 2022 - Researchers in Sweden used a large population sample from a national registry to analyze changes in sick leave and disability pension in patients from 2006-2017, before and after they were implanted with spinal cord stimulation for chronic pain, compared to a reference group. (neuromodulation.com)
Aug. 26, 2022 - A recent scientific presentation described the first implantation of Synchron's endovascular brain-computer interface as part of its U.S. COMMAND feasibility study in patients with severe paralysis. (neuromodulation.com)
Aug. 29, 2022 - A 6-month pilot trial published in Nature Medicine https://www.nature.com/articles/s41591-022-01941-w followed two patients with binge-eating disorder who were implanted with a responsive neurostimulation system that monitored activity in the nucleus accumbens, detecting and interrupting signals that had been associated in prior studies with food cravings. (neuromodulation.com)

[ 3 ] No single therapeutic algorithm has shown to be uniformly effective in preventing vasospasm and its subsequent neurologic sequelae, though a number of therapeutic strategies have found to have varying degrees of utility. (medscape.com)
The common therapeutic approach to patients, who develop vasospasm following subarachnoid hemorrhage, is usually composed of hypertension, hypervolemia, and hemodilution (HHH). (tau.ac.il)

If you have symptoms you definitely have to have yourself checked as vasospasms can cause a decrease in brain oxygenation. (behindthegray.net)
The findings from those studies on motor symptoms, medication requirements, quality of life, and independence in activities of daily living in PD patients are summarized and presented in tabulated form in this paper at the end. (neurologyindia.com)

Initial presenting head CT scan showing subarachnoid hemorrhage and blood filling basal cisterns. (medscape.com)

Previous studies have shown that levels of MMP-9 in the spinal fluid of patients with subarachnoid hemorrhage are elevated and suggest that these elevated levels may correlate with vasospasm development. (wustl.edu)
Platelet-derived growth factor (PDGF)-β levels rise following SAH and correlate with incidence and severity of vasospasm. (houstonmethodist.org)

within the last decades several clinical trials were performed to analyze the effectiveness of cisternal and ventricular lavage on cerebral vasospasm in patients suffering from subarachnoid hemorrhage. (nih.gov)
so far the literature search revealed a total of nine clinical trials using cisternal or ventricular lavage alone in patients suffering from subarachnoid hemorrhage. (nih.gov)

7. Garfinkle AM, Danys IR, Nicolle DA, Colohan AR, Brem S. Terson's syndrome: a reversible cause of blindness following subarachnoid hemorrhage. (cns.org)
To the best of our knowledge after extensive literature search, our case is the first to report cerebral vasospasm leading to reversible cerebral vasoconstriction syndrome [RCVS] after ingestion of the Carolina Reaper," he added. (medscape.com)

One case of wire-induced distal vessel injury was trapped with detachable coils without further neurological detriment of the patient. (bmj.com)

Anatomy21

Organisms3

Diseases55

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Psychiatry and Psychology1

Phenomena and Processes8

Disciplines and Occupations1

Information Science4

Health Care11

Spontaneous6

Aneurysm13

Acute12

ASAH28

Severe vasospasm2

Intra-arterial4

Mortality7

Symptomatic vasospasm2

Complications5

Etiology2

INTRACEREBRAL HEMORRHAGE2

Angiography5

Continues to be a major complication1

Ischemia3

Neurosurgery1

Likelihood of vasospasm1

Risk of vasospasm2

Incidence of vasospasm4

Infarction1

Aneurysms3

Stroke9

Hypertensive1

Diagnosis5

Outcomes7

Hydrocephalus1

Outcome in patients2

Refractory6

Recurrence1

Traumatic Brain2

Pulmonary artery c1

Prevention3

Perfusion1

Required HHH therapy1

Methods3

Workup1

Posterior3

Hypervolemic1

Surgery2

Deficits2

20223

Therapeutic2

Symptoms2

Basal1

Correlate2

Clinical trials2

Reversible2

Coils1