Sub cutaneous adipose tissue. Medical search. Frequent questions

The following public debate carries you from the evolutionary origins and the key functional purposes of adipose tissue, via adipose-derived stem cells and adipokines straight to the neuroendocrine, immunomodulatory and central nervous effects of signals that originate in the subcutis - perhaps, the most underestimated tissue of the human body. (femininebeauty.info)
This study aimed to assess whether the use of adult stem cells from adipose tissue is beneficial to skin healing. (rbcp.org.br)
The adult stem cells used were autologous and were extracted from infraumbilical adipose tissue prior to abdominoplasty. (rbcp.org.br)
Skin healing results after implantation of adult stem cells derived from adipose tissue were satisfactory. (rbcp.org.br)
For this purpose, mesenchymal stem cells were isolated from canine adipose tissue and bee venom samples were collected from Apis mellifera anatoliaca in Muğla province of Türkiye. (trdizin.gov.tr)
The regenerative effectiveness of cell-assisted lipotransfer is dependent on the presence of adipose tissue-derived stem cells (ADSCs). (archive.org)
Zhaoqi Yuan, Zhu Zhu, Fangxing Zhu, Feixue Ding, Yinmin Wang, Xiuxia Wang, Xusong Luo, Jun Yang, Fei Liu, Di Sun. 'Impact of human adipose tissue-derived stem cells on dermatofibrosarcoma protuberans cells in an indirect co-culture: an in vitro study. (archive.org)
Among these, adipose-derived stem cells (ADSCs) are a type of mesenchymal stem cell isolated from adipose tissue, which has the advantages of abundant storage in vivo , easy acquisition, and expansion [ 13 - 15 ]. (hindawi.com)
Recently, a number of studies have confirmed that ADSCs possess the ability to differentiate into adipocytes, osteoblasts, and chondrocytes [ 16 - 18 ], suggesting that a broader source of stem cells is available for application in tissue engineering. (hindawi.com)
Adipose tissue-derived stem cells display multi-lineage developmental plasticity, very much like bone marrow-derived mesenchymal stromal cells (BM-MSCs), and can differentiate into several cell lines, including adipocytes, chondrocytes and osteoblasts, as well as endothelial and neural lineages. (dermatologytimes.com)

The bone marrow- and adipose tissue-derived MSCs were cultured under human platelet lysate conditions and their biological characteristics evaluated for cell therapy (morphology, immunophenotype, colony-forming unit-fibroblast efficiency, proliferation capacity, potential for mesodermal differentiation, secreted proteins, and immunomodulatory effects). (biomedcentral.com)
However, bone marrow-derived MSCs possessed higher capacity toward osteogenic and chondrogenic differentiation compared with adipose tissue-derived MSCs, while similar adipogenic differentiation potential wase observed between the two types of cells. (biomedcentral.com)
MSCs, as a source of tissue cells, have the potential for self-renewal and differentiation, and they can realize functional tissue repair through self-differentiation and paracrine signaling. (biomedcentral.com)
Apocrine skin carcinoma has characteristics similar to those of cutaneous breast carcinoma metastases when it presents a tubule-lobular, or cordonal differentiation. (bvsalud.org)

Numerous studies have shown that mesenchymal stromal cells (MSCs) promote cutaneous wound healing via paracrine signaling. (biomedcentral.com)

Over the past decade, MSCs which are isolated from the umbilical cord, umbilical cord blood, bone marrow (BM), adipose tissue (AT) and many other adult tissues have been explored as potential therapeutic strategies for a number of diseases [ 2 ], but AT and BM are the most widely used sources of MSC, especially in autologous cell-based therapies due to ease of harvest and potential autologous application [ 3 ]. (biomedcentral.com)
Background Autologous adipose tissue transfer may be performed for aesthetic needs following the resection of dermatofibrosarcoma protuberans (DFSP), the most common cutaneous soft tissue sarcoma, excluding Kaposi sarcoma. (archive.org)
Background: Autologous adipose tissue switch could also be carried out for aesthetic wants following the resection of dermatofibrosarcoma protuberans (DFSP), the commonest cutaneous smooth tissue sarcoma, excluding Kaposi sarcoma. (cellexusinc.com)

The main purpose of radiofrequency (RF)-based devices for body contouring is to produce thermal stimulus which leads to skin tightening effect by dermal collagen production and decreases the volume of adipose tissue by a reduction of the adipocyte's cytosolic. (scirp.org)
Adipocytes are intimately associated with the dermal compartment of the skin, existing in a specialized dermal depot and displaying dynamic changes in size during tissue homeostasis. (horsleylab.org)
We discuss and speculate on potential roles of dermal adipocytes in cutaneous biology with an emphasis on communication during hair follicle growth and wound healing. (horsleylab.org)
Finally, we explore how alterations in the dermal adipose tissue may support clinical manifestations of cutaneous diseases such as lipodystrophy, obesity, and alopecia. (horsleylab.org)
While researchers agree on the abundance of Tregs in distinct dermal layers, the exact involvement of Tregs in cutaneous wound healing remains to be elucidated [ 18 ]. (biomedcentral.com)
This suggests that pressure-induced regulation of cutaneous blood flow may be altered by changes in dermal adiposity. (iah2010.org)
Mechanistically, numerous features of obesity-associated metabolic deregulation could impact dermal microvascular functionality NK-252 through local paracrine interactions with expanding adipose tissue. (iah2010.org)

But where the muscular fibers join the tendon or aponeurosis at an oblique angle, they end, according to Kölliker, in rounded extremities which are received into corresponding depressions on the surface of the latter, the connective tissue between the muscular fibers being continuous with that of the tendon. (bartleby.com)
These epidermal and connective tissue layers protect against mechanical and chemical harm and repel pathogenic invaders [ 19 ]. (biomedcentral.com)
The cause of cellulite is a breakdown in the support structure of connective tissue and fat cells. (wellvillespa.com)
Copper is required along with zinc for connective tissue health. (wellvillespa.com)
Zinc is required for connective tissue strength and flexibility. (wellvillespa.com)
The urethra is composed of membranous connective tissue and links the urinary bladder to the vestibule externally. (medscape.com)

377- Subcutaneous tissue from a young rabbit. (bartleby.com)
Fat is entirely absent in the subcutaneous tissue of the eyelids, of the penis and scrotum, and of the labia minora. (bartleby.com)
Piece consisting of the subcutaneous tissue with skin obtained from the dorsal-lumbar region, exclusively from pigs, subjected to the corresponding salting, curing and ageing process, which ensures good stability, as well as a characteristic smell and taste. (joselito.com)
A skin incision is made anteriorly, and the subcutaneous tissue is dissected from the iliotibial fascia itself as the skin and fat are retracted posteriorly. (medscape.com)
The mammalian skin consists of three main layers: the epidermis, the dermis, and the subcutaneous tissue, including the fascia (Fig. 1 ). (biomedcentral.com)

Another adverse effect is paradoxical adipose hypertrophy (PAH) which causes fat tissue to grow larger rather than become reduced in size as a consequence of the procedure. (wikipedia.org)
The second phase utilizes niacin, cantella asiatica, and cassia which has a lypolytic and defatting action due to improvement of the cutaneous microcirculation and reduction of hypertrophy of the adipose deposits. (wellvillespa.com)

[1] The concentrated cold delivered via a CoolSculpting device infiltrates the adipose layers of fat lining your "problem areas" without harming the skin or muscles surrounding them. (selfcarela.com)
Nova -Sculpt is a non-invasive therapy treatment for skin, muscles, tissues, circulatory and lymphatic systems. (insta-sculpt.com)
when verrucous carcinoma involves the plantar surface of the foot, it is named carcinoma cuniculatum (CC). Metastasis from CC is rare, although it can invade deep into the soft tissues and can extend to tendons, muscles, or bone. (units.it)
Communication n° 568 Introduction Mutations in LMNA encoding Lamins A/C are responsible of several disorders named laminopathies involving striated muscles as well as adipose, nervous, cutaneous and skeletal tissues. (myobase.org)
Finally, the vestibular bulbs are 2 masses of erectile tissue that lie deep to the bulbocavernosus muscles bilaterally. (medscape.com)

Primary cutaneous B-cell lymphoblastic lymphoma in children. (medscape.com)
Upon ordering laboratory tests recently for a patient with cutaneous T cell lymphoma, I included a lactate dehydrogenase (LDH) level, as I have done for decades, without giving it much thought. (aad.org)
In dermatology, LDH is characteristically part of the initial staging work-up of cutaneous lymphoma (including lymphomatoid papulosis) and melanoma. (aad.org)
The etiologic diagnosis of EN was made in 38 children (55.9%): 29 (42.6%) had infection-related EN (in particular EBV and ß-hemolytic streptococcus), 6 (8.8%) had Crohn's disease, 1 celiac disease, 1 Sjogren syndrome, and 1 Hodgkin lymphoma. (bvsalud.org)

Loss of tissue is then repaired in a complex process that involves tissue-resident immune, stromal, and epithelial cells, as well as infiltrating immune cells [ 2 ]. (biomedcentral.com)

The dorsal portions fuse to form the lateral femoral cutaneous nerve in the midpelvic region of the psoas major. (bizwan.com)

Hansson E, Svensson H, Stenram U, Brorson H. Histology of adipose tissue inflammation in Dercum's disease, obesity and normal weight controls: a case control study. (medscape.com)
Skin histology examination showed cutaneous and subcutaneous fibrinoid necrosis with bleeding, abscess, neutrophil-rich cellular infiltration, and the presence of PAS-, Grocott- and mucin-positive spores. (medihelp.life)

The degree of exposure to cooling causes cell death of subcutaneous fat tissue, without apparent damage to the overlying skin. (wikipedia.org)
Based on the premise that fat cells are more easily damaged by cooling than skin cells (such as popsicle panniculitis), cryolipolysis was developed to apply low temperatures to tissue via thermal conduction. (wikipedia.org)
Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver. (umassmed.edu)
The current edition of the journal Experimental Dermatology is featuring many articles on the functions of subcutaneous (beneath the skin) adipose cells (fat cells). (femininebeauty.info)
Our acute awareness of the cosmetic, psychosocial and sexual importance of subcutaneous adipose tissue contrasts dramatically with how poorly we have understood the biology of this massive, enigmatic, often ignored and much-abused skin compartment. (femininebeauty.info)
However, already the distribution of human superficial adipose tissue, by itself, questions how justified the popular belief is that 'skin fat' (which actually may be more diverse than often assumed) serves primarily thermoinsulatory purposes. (femininebeauty.info)
Main purposes of RF-based devices are skin tightening and decrease the volume of adipose tissue. (scirp.org)
4 As this case illustrates, heparin-induced skin necrosis typically begins as a tender, small, erythematous macule that evolves into a larger, dusky, and variably necrotic patch that often features a central bulla.6 Necrosis typically develops at the site of heparin administration and preferentially occurs at sites rich in subcutaneous adipose tissue (e.g., abdomen, thighs, buttocks, and breasts). (clinicaladvisor.com)
Others postulate that the skin findings are the result of cutaneous trauma caused by repeated, improperly performed injections, or that heparin may be poorly absorbed due to decreased vasculature in adipose tissue. (clinicaladvisor.com)
Cutaneous manifestations of cirrhosis include jaundice, spider angiomata, skin telangiectasias ("paper money skin"), palmar erythema, white nails, disappearance of lunulae, and finger clubbing, especially in the setting of hepatopulmonary syndrome. (medscape.com)
It connects the skin with the deep fascia, and consists of fibroareolar tissue, containing in its meshes pellicles of fat in varying quantity. (bartleby.com)
Skin Cutaneous melanoma (SKCM) is a highly aggressive malignant neoplasm that develops from uncontrolled proliferation and transformation of melanocytes. (fortunepublish.com)
Cutaneous wound healing is a temporally- and spatially-synchronized cascade of cellular and immune responses dedicated to re-establishing skin integrity and function [ 3 ]. (biomedcentral.com)
Aging causes changes in the structural foundations of skin, hair, and nail tissue. (lifeextension.com)
General term for inflammation of adipose tissue, usually of the skin, characterized by reddened subcutaneous nodules. (bvsalud.org)

Merkel Cell Carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma which is characterized by high incidence of early loco-regional relapse and distant metastases (Poulsen 2004 ). (springeropen.com)

The incidence of cutaneous malignant melanoma has been steadily increasing over the last four decades in predominantly fair-skinned populations [6]. (fortunepublish.com)

Cutaneous biopsy in progressive lipodystrophy reveals a reduction or absence of subcutaneous fat in affected areas. (medscape.com)
Adipose-specific knockout of SEIPIN/BSCL2 results in progressive lipodystrophy. (medscape.com)
Lipodystrophy refers to the loss of adipose tissue. (medscape.com)

In order to avoid frostbite, a specific temperature level and exposure are determined, such as 45 minutes at −10 °C (14 °F). While the process is not fully understood, it appears that fatty tissue that is cooled below body temperature, but above freezing, undergoes localized cell death ("apoptosis") followed by a local inflammatory response that gradually over the course of several months results in a reduction of the fatty tissue layer. (wikipedia.org)
Nova sculpt works on breaking down fatty deposits, cellulite, separating adipose clusters, improving cutaneous tissues, and evacuating it's with excess fluid through the lymphatic areas. (insta-sculpt.com)
This phase heats the fatty tissues softening them allowing the trapped toxins to then be evacuated through the kidneys via the lymphatic and circulatory system. (wellvillespa.com)

Our Cutaneous Translational Research Program (CTReP) is our center for scientists to collaborate and conduct clinical research trials. (hopkinsmedicine.org)
Primary cutaneous cryptococcosis (PCC) is a clinical entity, differing from secondary cutaneous cryptococcosis and systematic infection. (medihelp.life)
The present study aimed to report all the cases of children admitted to our tertiary pediatric hospital with the diagnosis of EN to evaluate the epidemiology, clinical manifestations, etiology, treatment, and the course of this disease in the pediatric age. (bvsalud.org)
Clinical symptoms of HCB poisoning still were present in survivors 20 years later, including hyperpigmentation, hirsutism, cutaneous scarring, small stature and small hands, painless arthritis, enlarged liver, and enlarged thyroid. (cdc.gov)

In the subcutaneous adipose tissue, near the lesion, there were several hyperdense strands [Figure 1c and d arrowhead], which were not infiltrative aspects of the tumor, but rather vascular structures. (units.it)
This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)

Reduction of the adipocyte's cytosolic volume by normal lipolysis without direct cellular destruction is also obtained due to heat generation in the tissue. (scirp.org)

They performed comparative studies of the cutaneous malignancy and breast nodules, especially with immunohistochemical examinations. (bvsalud.org)

Some of these have been implicated in perivascular adipose tissue-mediated, endothelial cell dysfunction in arteries and arterioles [12, 13]. (iah2010.org)

Merkel cell carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma. (springeropen.com)

Unfortunately, in some cases these antibodies cross-react with normal tissues and destroy them, which may result in a paraneoplastic disorder. (medscape.com)
We observed a statistically significant increased messenger RNA (mRNA) expression in E2F1/3/5/7 compared with matched normal tissues. (fortunepublish.com)

Furthermore, ADSCs are known to have various cytokine-secreting properties and beneficial paracrine effects on surrounding cells or tissues through secretion of multiple angiogenic and antiapoptotic growth factors, including vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), basic fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF). (dermatologytimes.com)

Kawaguchi M, Kato H, Tomita H, Hara A, Matsuo M. CT and MR imaging findings of solitary nevus lipomatosus cutaneous superficialis: radiological-pathological correlation. (medscape.com)

They have a higher water content and a different lipid composition compared to other tissues. (skinzonemedical.com)
Patent - Monitoring the cooling of sub-cutaneous lipid rich cells, such as the cooling of the adipose tissue. (coolsculptingin.com)

However, bone marrow-derived MSCs and adipose tissue-derived MSCs have not yet been directly compared with each other under human platelet lysate conditions. (biomedcentral.com)
Under human platelet lysate-supplemented culture conditions, bone marrow- and adipose tissue-derived MSCs exhibited similar fibroblast-like morphology and expression patterns of surface markers. (biomedcentral.com)
Adipose tissue-derived MSCs had greater proliferative potential than bone marrow-derived MSCs, while no significantly difference in colony efficiency were observed between the two types of cells. (biomedcentral.com)
There were some differences between bone marrow- and adipose tissue-derived MSCs for several secreted proteins, such as cytokine (interferon-γ), growth factors (basic fibroblast growth factor, hepatocyte growth factor, and insulin-like growth factor-1), and chemokine (stem cell-derived factor-1). (biomedcentral.com)
Adipose tissue-derived MSCs had more potent immunomodulatory effects than bone marrow-derived MSCs. (biomedcentral.com)

Two vials were administered to the left lateral thigh (20cm2 surface area of soft tissue thickness 4cm), and one vial to the right lateral thigh (10cm2 surface area of soft tissue thickness 4cm). (aestheticsjournal.com)
The anterior branch comes off 10 cm distal to the inguinal ligament in line with the ASIS, and supplies cutaneous sensation to the lateral thigh, including just proximal to the patella. (bizwan.com)

Percutaneous lateromedial ultrasonographic image of the enlarged left mammary gland of the filly described in Figure 1 showing an accumulation of fluid (black arrow) in the mammary gland, homogeneously hyperechoic mammary tissue (double-headed arrow), and the medial lamina (white arrows) between the 2 halves of the udder. (avma.org)

Follow-up biopsies showed reductions in perivas- evidence of inflammatory infiltrate in lymphedematous cular mononuclear infiltrate in the superficial dermis (41% tissue (14,15). (cdc.gov)

These include obesity-associated impaired metabolic functionality of adipose tissue, altered adipokine production [9] and low-grade chronic inflammation (metaflammation) [9C11]. (iah2010.org)

Tissue Engineering Part B: Reviews 2020;26(6):555-570. (trdizin.gov.tr)

They were initially found in the bone marrow [ 11 ] but can also be found in other tissues, such as adipose, periosteum, muscle, placenta, and trabecular bone [ 12 ]. (hindawi.com)

Focused thermal ultrasound techniques work by raising the tissue temperature up to 48 °C, resulting in coagulative necrosis of adipocytes, with sparing of vessels and nerves. (wikipedia.org)
However, the roles of adipocytes in cutaneous biology and disease are not well understood. (horsleylab.org)
Traditionally, adipocytes within tissues were thought to act as reservoirs of energy, as thermal, or as structural support. (horsleylab.org)

Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess abdominal adipose tissue), hypertension, abnormal fasting plasma glucose or insulin resistance, and dyslipidemia. (msdmanuals.com)

A 73-year-old woman presented with a hard mass in the adipose tissue of the right inguinal area. (springeropen.com)
A 73-year-old woman with no prior medical history, presented with a hard mass (diameter = 46 mm) in the adipose tissue of the right inguinal area which was confirmed by CT scan (Nov 2009). (springeropen.com)

The cells of areolar tissue are of four principal kinds: (1) Flattened lamellar cells, which may be either branched or unbranched. (bartleby.com)
The cells lie in spaces in the ground substance between the bundles of fibers, and these spaces may be brought into view by treating the tissue with nitrate of silver and exposing it to the light. (bartleby.com)
What sets CoolSculpting apart is its ability to selectively target fat cells while leaving surrounding tissues unharmed. (skinzonemedical.com)
To this end, multiple tissue-resident cells and recruited immune cells cooperate to efficiently repair the injured tissue. (biomedcentral.com)
In this context, regulatory T cells (Tregs) hold a key role in balancing immune homeostasis and mediating cutaneous wound healing. (biomedcentral.com)
This function of the cutaneous system is mediated by a myriad of highly specialized immune cells. (biomedcentral.com)
Specifically, the timely orchestration of pro- and anti-inflammatory responses, based on the activation and inhibition of various cell types, such as tissue-resident cells and different types of immune cells, can significantly impact wound repair [ 7 ]. (biomedcentral.com)
The collagen and elastin fibers harden causing fat cells to swell losing their symmetry and trapping toxic fluids within the adipose tissue. (wellvillespa.com)
Indeed, the final outcomes suggested a better performance of cells coming from subcutaneous adipose tissue vs. those from visceral fat tissue. (uniba.it)

We evaluated the importance of weight and fat tissue on bone mass at premenopausal or postmenopausal women in a cross-sectional study upon a group of 138 women between 25 and 77 ys old and with a BMI between 17.1 and 44.3 kg/m2. (endocrine-abstracts.org)
CT did not show any deep invasion affecting the plantar aponeurosis and calcaneus bone with an evident cleavage plane represented by adipose tissue. (units.it)
4,5] MRI can discriminate better between different types of soft tissue pathology than CT, but not so precisely an early bone invasion. (units.it)
4] Hence, it is crucial to evaluate the evidence of possible bone involvement on imaging with CT for a correct surgical approach in all CC with a high risk of bone and periosteal tissues invasion. (units.it)

Ectopic fat in tissues such as liver and muscle may be increased. (medscape.com)

Zinc deficiency and cellulite: Low tissue zinc may also have to do with cellulite formation. (wellvillespa.com)

Erythema nodosum (EN), although relatively uncommon in the pediatric population, is the most frequent type of panniculitis in children. (bvsalud.org)

The cumulative loss of fat leads to a decrease in adipose-derived adiponectin and leptin. (medscape.com)

It also presents a case study with long-lasting cutaneous adverse events associated with deoxycholic acid administration for local excessive adipose tissue and our approach to management. (aestheticsjournal.com)

Approximately 60% of solitary cutaneous lipomas display clonal alterations. (medscape.com)

Lipomas typically develop as discrete rubbery masses in the subcutaneous tissues of the trunk or proximal extremity. (medscape.com)

5. Hozzein WN, Badr G, Al Ghamdi AA, Sayed A, Al-Waili NS, Garraud O. Topical application of propolis enhances cutaneous wound healing by promoting TGF-beta/Smad-mediated collagen production in a streptozotocin-induced type I diabetic mouse model. (trdizin.gov.tr)

It has been hypothesized that the biodynamic responses of the human finger tissues to vibration are among the major stimuli that cause vibration health effects. (cdc.gov)

They vary in size and distribution from female to female, and the size is dependent upon adipose content. (medscape.com)

The maintenance of tissue homeostasis and proper wound healing is, therefore, a critical process that can be disturbed by a plethora of external and internal factors. (biomedcentral.com)

Meanwhile, the surrounding tissues, such as blood vessels, nerves, and collagen fibers, have a different composition that makes them more resistant to the cooling process. (skinzonemedical.com)

Fever is thought to result from the release of endogenous pyrogens (ie, lymphokines or tissue pyrogenes). (medscape.com)

Anatomy32

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Psychiatry and Psychology3

Phenomena and Processes56

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Subcutaneous tissue5

Hypertrophy2

MUSCLES5

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Stromal1

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Clinical4

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MSCs5

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20201

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Metabolic1

Inguinal2

Cells9

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Decrease1

Excessive1

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