• Researchers gathered input through community visits, local meetings, chats and seminars, which resulted in community influence on study decision-making occurring at all stages of the research process. (who.int)
  • For this study, researchers at the Wellcome Sanger Institute isolated Tregs from 124 healthy individuals to map how genetic variants regulated the expression of genes and function of the cells. (sanger.ac.uk)
  • Genetic variants predisposing individuals to immune diseases were linked to a total of 91 genes, 31 of which were specifically impaired in Tregs but not in other immune cell types investigated by the researchers. (sanger.ac.uk)
  • Researchers investigated gender disparities in a mental rotation task spanning 53 civilizations. (tutorialspoint.com)
  • Budding yeast, S. cerevisiae, has been used extensively as a model organism for studying cellular processes in evolutionarily distant species, including humans. (biomedcentral.com)
  • Many studies have extensively investigated the molecular mechanisms involved in cell migration and have recognized the Rho small GTPases as key regulators of actin dynamics 7 , 8 . (nature.com)
  • By cross-referencing these data against chromatin activity and gene expression regulation, we were able to narrow down the genes involved in immune disease from thousands to less than a hundred. (sanger.ac.uk)
  • Unpaid caregiving roles and sleep among women work ing in nursing homes: a longitudinal study. (cdc.gov)
  • A recent study by Dr. BongKyoo Choi at University of California Irvine, Job Strain, Long Work Hours, and Suicidal Ideation in US Workers: A Longitudinal Study , addresses aspects of work that can impact suicidal ideation, or suicidal thoughts, in workers. (cdc.gov)
  • RESEARCH DESIGN AND METHODS -We conducted cross-sectional and prospective analyses of diabetes status and lung function decline using baseline and 3-year follow-up data on 1,100 diabetic and 10,162 nondiabetic middle-aged adults from the Atherosclerosis Risk in Communities (ARIC) Study. (diabetesjournals.org)
  • Research Design and Methods: The sample comprised 1,135 women long-term care employees who participated in the baseline wave of the Work , Family , and Health Study and were assessed at three follow-up time points (6-, 12-, and 18-months). (cdc.gov)
  • Design may include cross- sectional surveys, longitudinal studies, monitoring and evaluation methods, and randomized trials. (who.int)
  • Qualitative research uses methods such as the collection of narrative or interview data to explore meanings and relationships and might be used to investigate sensitive topics related to mental health. (who.int)
  • METHODS: The present original research study was conducted at Zhejiang University City College, Hangzhou, Republic of China, from 2020 to 2022. (bvsalud.org)
  • BACKGROUND: Responding to calls for additional research that identifies effective distress screening (DS) processes, including referral practices subsequent to screening and receipt of recommended care, we engaged in qualitative research as part of a larger (mixed methods) study of distress screening. (cdc.gov)
  • Methods: a descriptive cross-sectional survey was conducted using structured questionnaires to 431 randomly selected households. (bvsalud.org)
  • Patients and methods: This study was carried out on 100 Helicobacter pylori (H. pylori)-infected patients (within the period between septemper, 2018 to May, 2019) who were enrolled from Hepatology, Gastroenterology & Tropical Medicine Department, Al Azhar University Hospitals (El-Hussein and BAB El-Shaarea). (bvsalud.org)
  • Though there is a lot of further study to be done to pinpoint the precise biological mechanisms involved, we are one step closer to doing that and to developing effective treatments. (sanger.ac.uk)
  • The purpose of this study was to examine how interpreters see their work within the context of the integration of immigrants into the host society (Switzerland) in general, and into the local health system in particular. (benjamins.com)
  • The current cross-sectional study aims to examine whether there is an association between the lifetime number of sex partners and being sexually satisfied, with gender, the current relationship status and approach- and avoidance sexual motivations as possible moderators of this association. (uu.nl)
  • The purpose of this study was to investigate the social co-construction of masculinities and sexual development among VYMA aged 10 - 14 years living in Korogocho slum of Nairobi, Kenya and to examine how slum contexts shape the co-construction of masculinities and sexual development. (wits.ac.za)
  • Main objectives of the study are to examine the exposure of young viewers towards Private TV Dramas and to examine the positive feelings of young viewers towards Private TV Dramas. (gmmrjournal.com)
  • In addition, it is also objective of the study to examine the negative feelings of young viewers towards Private TV Dramas. (gmmrjournal.com)
  • This study is set in the Chicana Feminist Epistemology and applies the theoretical framework, Latino Critical Theory (LatCrit) as the lens in which to examine the participant's experiences and the intersectionality of race, class, and gender. (csulb.edu)
  • Currently, there are only a few longitudinal studies that examine chronic psychosocial work stressors related to attempted suicide or mortality in working populations (Milner et al 2018), and few control for family history. (cdc.gov)
  • The Violence Tendency and Attitudes Towards Women Scales were applied to show the perceptions of adolescents of social roles. (who.int)
  • This study documents student and staff perceptions of the implementation of the Los Angeles Unified School District (LAUSD) Seal of Biliteracy Awards Program at one high school with a predominantly Latino student population. (csulb.edu)
  • As a result of their roles as minorities, and notwithstanding their differing perceptions of their position within the project, the organisations both present the idea of being European as compatible with the religious identification. (lu.se)
  • This descriptive study, comprising 2321 high school students, was conducted in Izmir, Turkey, between May and August 2015. (who.int)
  • The method: The study used a quantitative, cross-sectional descriptive design, with a self-administrative questionnaire as the data collection instrument. (alquds.edu)
  • These data were then cross-referenced against variants associated with increased risk of developing immune diseases 1 , in order to hone in on the genes that play pivotal roles in disease pathogenesis. (sanger.ac.uk)
  • Overall, our data clearly showed that Lea has a pivotal role in the recognition of HuNoV in nonsecretors. (bvsalud.org)
  • The Lea antigen also played a pivotal role in the recognition of GII.4 and GII.17 particles by inflammatory colon tissue from a nonsecretor Crohn's disease patient. (bvsalud.org)
  • We further study each of these subspaces in detail, and shed light on their unique biological roles in the human tissues. (biomedcentral.com)
  • Environment and Radiation (ENV) are well as biological factors throughout the in their work, and by using the general to investigate environmental, lifestyle, course of the disease. (who.int)
  • A qualitative study within the project RundUm - Transcultural network in the care of pregnancy and birth / Herausforderungen und Chancen bei der Hinzuziehung von Sprach- und Integrationsmittlerinnen in die Regelversorgung von Schwangeren und jungen MĂĽttern aus Drittstaaten. (benjamins.com)
  • The purpose of this qualitative study is to shed light on the personal, educational, professional, and trusteeship journey of five Chicana/Latina trustees. (csulb.edu)
  • Thus, the goal of this study was to analyze the ability of ADAM8-positive EVs isolated from the serum of PDAC patients and miRNAs as cargo of serum EVs, also involving PRMT1 and PRMT4, to distinguish precursor lesions or PDAC fro m healthy controls. (uni-marburg.de)
  • This study aimed to analyze differences in opinions about contraception based on self-reported sexual and contraceptive behavior. (bvsalud.org)
  • Regulatory T cells (Tregs) are a relatively rare immune cell type that play a key role in controlling human immune response. (sanger.ac.uk)
  • These associations have been supported by studies that have found that immune disease patients carry Tregs that do not function properly, or are present in abnormal numbers. (sanger.ac.uk)
  • This study is an important step towards understanding how genetic variants influence the function of Tregs and what role this can play in disease. (sanger.ac.uk)
  • We are also investigating tissue Tregs and have recently found important roles for these cells in regulating the early innate immune response in both type 1 and type 2 responses. (massgeneral.org)
  • Projects in the lab are currently aimed at uncovering roles for antigen-specific tissue Tregs in regulating antigen-specific resident memory effector T cell responses in tissue. (massgeneral.org)
  • This study analyses the marketing strategy implemented in SMEs. (icesi.edu.co)
  • Yet, no systematic review exists that synthesizes LE studies, identifies gaps in the literature, and suggests future research directions. (researchgate.net)
  • Countless studies over the past 3 decades have evaluated the impact of various individual tenderness contributing components on meat tenderness, such as proteolysis, sarcomere length, muscle fiber cross-sectional area, fat content and fatty acid profile, collagen content and collagen crosslinks…etc. (beefresearch.org)
  • Over the last two decades, studies based on genome-wide gene expression and functional profiling have revealed the great diversity of transcriptional alterations occurring in liver carcinogenesis. (aging-us.com)
  • The lab investigates roles for peptide hormones in root development and utilizes a broad range of techniques in cell biology, molecular biology, genetics, developmental biology, proteomics, chemistry, bioinformatics and plant physiology. (edu.au)
  • We investigated what proportion of the population acquired severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and whether the herd immunity threshold has been reached in 10 communities in Qatar. (cdc.gov)
  • The Luster Laboratory at Massachusetts General Hospital investigates chemokines, lipid chemoattractants and their receptors in normal physiology and disease. (massgeneral.org)
  • Our framework provides a novel tool that can be used to assess the suitability of the yeast model for studying tissue-specific physiology and pathophysiology in humans. (biomedcentral.com)
  • Thus, we are entering a new era to investigate a question of how molecular signals are dynamically processed through signaling cascade. (nature.com)
  • Feshbach resonances have become important in the study of cold atoms systems, including Fermi gases and Bose-Einstein condensates (BECs). (wikipedia.org)
  • Further discussion is needed about whether these additional roles should be recognized and promoted as part of their work since they are important and there is no one else to take them on. (benjamins.com)
  • Interpreters who take on the additional roles related to integration have the potential to be important actors in health care services whose patient populations that are increasingly linguistically and culturally diverse. (benjamins.com)
  • Surprisingly, with the addition of PD, we observed that the processing conditions and temperatures play important roles in the structure and performance of these materials. (rsc.org)
  • The study, published in Cell Genomics , identified 91 unique genes that play an important role in immune diseases, such as asthma and Crohn's disease, by influencing how regulatory T cells function. (sanger.ac.uk)
  • The social environment may play an important role in shaping health behaviors, we however, lack knowledge regarding the exact influence of the social environment on older persons' physical activity levels. (biomedcentral.com)
  • In promoting active aging, consideration of the role of the social environment and ensuring that it is supportive of older people's physical activity are important. (biomedcentral.com)
  • The social environment may play an important role in shaping health behaviors, in addition to the most important enablers/disablers of physical activity among community-dwelling older adults: advanced age, income, and educational level [ 13 ]. (biomedcentral.com)
  • p53 is a transcription factor that plays an important role in preventing cancer development. (molvis.org)
  • This study suggests that creating and maintaining a healthy work organization should be an important strategy for the prevention of suicide in working populations. (cdc.gov)
  • Previous studies have linked genetic variants that affect Treg function to immune diseases such as type-1 diabetes and rheumatoid arthritis. (sanger.ac.uk)
  • The role of chemokines in regulating the immune response to tumors and cancer immunotherapy is also studied. (massgeneral.org)
  • OBJECTIVE -The aim of this study was to test the hypothesis that diabetes is independently associated with reduced lung function, both cross-sectionally and longitudinally. (diabetesjournals.org)
  • The objective of this study was to obtain preliminary data to better understand the contribution of each tenderness factor to the perception of tenderness of three specific beef muscles with similar tenderness rating. (beefresearch.org)
  • However, Ucp2 displays a wide tissue expression range ( 5 ), and its roles in various tissues and cell types have not been covered. (bmbreports.org)
  • One approach that promotes this is participatory action research, or PAR, which is a way to engage study participants in active co-researcher roles. (who.int)
  • In the area of attitude, the current study found that most participants had a passion for providing proper care to stroke patients. (alquds.edu)
  • The study included 4,970 participants during June 21-September 9, 2020. (cdc.gov)
  • The study included focus group interviews with 26 high school student participants, primarily female and mostly in the 12th grade, and individual interviews with six staff participants in various capacities with an educational experience ranging from five to 25 years. (csulb.edu)
  • Violence affects more than half of women worldwide and the perception of social roles has a significant role in this. (who.int)
  • however, its role in adipose tissue is not fully understood. (bmbreports.org)
  • In the present study, we have investigated the role of Ucp2 against high-fat diet (HFD)-induced obesity in epididymal white adipose tissue (eWAT) and browning of inguinal white adipose tissue (iWAT). (bmbreports.org)
  • To study the role of Ucp2 in adipose tissue, we have examined HFD-induced obesity and β3 adrenergic stimulation in Ucp2 KO mice. (bmbreports.org)
  • Our study also showed that Ucp2 deletion alleviates HFD-induced weight gain and adipose tissue inflammation by blocking adipocyte apoptosis, an event preceding the recruitment of macrophages and proinflammatory cytokine secretion. (bmbreports.org)
  • One unifying principle under investigation is determining the role of specific chemokine systems in establishing tissue niches for the differentiation and maintenance of specific T cell populations, such as resident memory T cells in the lung and stem-like CD8 + and CD4 + T cells in the tumor microenvironment. (massgeneral.org)
  • Saliva binding assays showed that only GII.4 interacted with nonsecretor saliva via the Lewis a (Lea) antigen Surprisingly, the three genotypes interacted with nonsecretor enterocytes via the Lea antigen on duodenal tissue blocks, which were more relevant for HuNoV/HBGA studies. (bvsalud.org)
  • To investigate the role of PRMT-1 and 4 on TME in PDAC, immunohistochemical staining was performed with the same stromal cells on human PDAC tissue as previously used to build a network of correlation. (uni-marburg.de)
  • Such masculine beliefs and norms, which are referred to as "gender norms" in the study were measured using a scale developed and validated in the context of the Global Early Adolescent Study. (wits.ac.za)
  • The next step for this research will be to investigate precisely how genes affect Treg function by simulating these interactions in the laboratory, which will provide more context for the development of new therapies. (sanger.ac.uk)
  • Paper III was a group comparison study in the context of a randomised controlled trial. (uib.no)
  • In this context the present study was illiterate. (gmmrjournal.com)
  • The myocardial nicheplays a critical role in directing the function and fate of cardiomyocytes;therefore, engineering a biomimetic scaffold holds excellent promise.We produced an electroconductive cardiac patch of bacterial nanocellulose(BC) with polypyrrole nanoparticles (Ppy NPs) to mimic the naturalmyocardial microenvironment. (ibecbarcelona.eu)
  • Therefore, the main aim of this study is to identify potential diagnostic biomarkers to detect PDAC at early stages. (uni-marburg.de)
  • Here, we studied the interaction of common HuNoV genotypes (GII.3, GII.4, and GII.17) in nonsecretor individuals using synthetic viral particles. (bvsalud.org)
  • We point out that both contributions can play a significant role in modulating the interaction strength between neurons or neuron populations. (mit.edu)
  • However, its diagnosis in early stages and the interaction partners in tumor stroma cross-talk remains still elusive. (uni-marburg.de)
  • In conclusion, cross-cultural approaches are beneficial for evaluating a variety of evolutionary hypotheses as well as for comparing conflicting ideas. (tutorialspoint.com)
  • Deoxyribonucleic acid damage caused by the irradiation caused higher level of poly- adenosinediphosphate-ribosylated Specific Protein 1(SP1), and translocation of SP1 from the nucleus, decreasing the expression of fucosyltransferase IV and Lewis Y. Conclusion: There was a significant role of glycosylation in radiation therapy for lung cancer. (bvsalud.org)
  • Investigating astrocyte maturation in a cell culture model revealed that in vitro-differentiated astrocytes lack expression of many mature astrocyte-specific genes, including genes for the transcription factors Rorb, Dbx2, Lhx2 and Fezf2. (nature.com)
  • Since strong consensus regarding commonly altered MRs in hepatocellular carcinoma (HCC) is lacking, we generated a compendium of HCC datasets from 21 studies and identified a comprehensive signature consisting of 483 genes commonly deregulated in HCC. (aging-us.com)
  • However, few studies have examined gender norms among very young male adolescents (VYMA) (ages 10 - 14), and the influence of gender norms on sexual behaviours of these young boys. (wits.ac.za)
  • A team has been building a prototype of a Identify people and roles of people in the community of website to improve the access of communities about environmental health professionals. (cdc.gov)
  • Our study suggests that Ucp2 deficiency may prevent diet-induced obesity by regulating adipocyte apoptosis. (bmbreports.org)
  • The study also used Connell's theory of gender and power to understand how gender was structured in the study setting, separating roles and expectations for men/boys and women/girls, more so in romantic relationships. (wits.ac.za)
  • After certain assumptions about evolved psychological systems and the corresponding expectations are developed, they must be investigated to understand and comprehend them. (tutorialspoint.com)
  • We present a population of patients with persistent symptoms as measured by a select number of PROMIS surveys (i.e. fatigue, sleep, pain, physical functioning, and social roles). (medrxiv.org)
  • In the present study, we investigated the role of Src family tyrosine kinases in the initial adhesion events of human platelets to collagen and cross-linked CRP. (reading.ac.uk)
  • She is a self-taught artist who mainly focuses on digital media and graphite-based works, Although Kristen likes a variety of art forms she mainly focuses on realism and life studies. (sitesantafe.org)
  • This study focuses on Chicana/Latina "Trailblazers" the first Chicana/Latinas to be elected to their district. (csulb.edu)
  • With this wide epidemiological studies, including coor- remit, ENV focuses its endeavours dination of international consortia or With a strong focus on environmental in three main areas: (i) research in through the initiation of targeted individual (including occupational and radiation- settings where levels of exposure to analytical epidemiological studies. (who.int)
  • While the function of ADAM8 in PDAC cells is already known, its role in tumor-associated cells remains elusive and no information is available on the expression profile of ADAM8 in cells of TME. (uni-marburg.de)
  • As part of the study 'Seks onder je 25e', a survey was conducted among 9,652 heterosexually identified, sexually active, Dutch 18-24 year-olds (M = 21.07 SD = 1.97). (uu.nl)
  • We hope that our chapter will help to highlight the importance of disaster mental health research and encourage new and innovative research studies in this area. (who.int)
  • Quantitative research may focus on the prevalence of mental health issues, their correlates, symptom course and the effects of intervention, using whichever study design is most appropriate to the topic being investigated. (who.int)
  • Her research interests include the preparation and design of materials and scaffolds for in vitro and in vivo fundamental studies, and a further focus is the provision of useful tools to assess mechanisms that govern cell behavior in regenerative medicine. (ibecbarcelona.eu)
  • Gratifying is that the interest continues and more studies and research can be conducted in all aspects of human rights of women and gender equality- the literature is there! (lu.se)
  • In previous research, this is attributable in part to the fact that the discussion emanates from people pertaining to the "centre," or more specifically, the majority of the populace.2 This initial struggle between the centre and those in the periphery forms the basis for this study. (lu.se)
  • To end violence against women, public health actions should focus on the young population and their representation of social roles. (who.int)
  • It is known that acceptance of violence is associated with varying factors, such as past exposure to violence, violence in the home, parental socioeconomic difficulties, cultural and social beliefs about the masculine and feminine social roles, and lack of job opportunities (7,8). (who.int)
  • Assessment of impairments in social roles and adverse impact on mental health could allow for early interventions and improved outcomes. (medrxiv.org)
  • This study looked at social co-construction of masculinities as a process in which boys' individual characteristics interact with their social environment to inform their masculine beliefs and norms. (wits.ac.za)
  • On the other hand, social role theory postulates that psychological gender disparities result from the roles that various cultures place on people and, as a result, should disappear when sex equality rises. (tutorialspoint.com)
  • According to social role theory, the gendered inequalities were somewhat higher in cultures with more gender diversity. (tutorialspoint.com)
  • The study used data from the National Survey of Midlife Development in the United States (MIDUS) II study (2004-2009), which examines the "roles of behavioral, psychological, and social factors in understanding age-related differences in physical and mental health. (cdc.gov)
  • The purpose of the study was to investigate whether chronic psychosocial work stressors (job strain, supervisor and coworker support, job insecurity, job control, and work hours) are longitudinally associated with suicidal ideation in a middle-aged US working population, particularly after controlling for a family history of suicide. (cdc.gov)
  • In this study, we focus on linearly filtered spike trains and particularly consider correlations caused by overlapping presynaptic neuron populations. (mit.edu)
  • to ensure that the involvement of the understand the cancer burden attributed (i ) studies of common cancers and of Agency makes a specific and substantial to these factors. (who.int)
  • Studies on SARS-CoV-2 in the lab focus on strategies to increase the breadth and cross-reactivity of the T and B cell response to vaccination to generate a pan coronavirus vaccine. (massgeneral.org)
  • The interpreters described four main roles: word-for-word interpreting, intercultural explanation, building patient-provider relationships, and accompanying immigrant patients. (benjamins.com)
  • The American Association for the Study of Liver Diseases recommends patients with CHB receive monitoring of disease activity, including ALT, hepatitis B virus (HBV) DNA, hepatitis B e-antigen (HBeAg), and liver imaging for patients who experience an increased risk for HCC. (stanford.edu)
  • However, there were few patients with M5 lesion locations (n = 19), and too few patients to investigate a relationship between other ASPECT locations and trunk control. (uib.no)
  • This study is aimed at investigating nurses' knowledge and attitude regarding their roles during the care of stroke patients while in rehabilitation. (alquds.edu)
  • The results Study findings showed that nurses have inadequate knowledge about the basic principles of rehabilitation for stroke patients in the area of patient management. (alquds.edu)
  • A total cohort of 72 PDAC patients and 20 healthy individuals as a comparison was used in this entire study. (uni-marburg.de)
  • Anesthesiologists will continue to play primary roles in optimizing patients' medical condition and safely guiding them through cardiac surgery with CPB. (medscape.com)
  • Areas of interest included the role of resident memory T cells in the lung in response to allergens in the asthmatic lung and to respiratory viral pathogens, such as SARS-CoV-2 and influenza, as well to vaccination. (massgeneral.org)
  • There is limited knowledge on trunk control after stroke, and further studies are warranted. (uib.no)
  • Although nurses have significant roles during this rehabilitation period, such as therapeutic practice, little is known about the knowledge and attitude of Palestinian nurses towards stroke rehabilitation. (alquds.edu)
  • There is a strong evidence that nurses should develop and integrate stroke-specific rehabilitation knowledge and skills in their practice, as well as additional stroke-specific training to integrate rehabilitation principles in their role and workplace. (alquds.edu)
  • Another consideration is the role that culture plays in the expression of distress. (who.int)
  • Physiotherapy is the most common rehabilitation intervention, and the role of the physiotherapist is mainly focussed on improvement in motor function. (uib.no)
  • one methodological, one translational and one intervention study. (uib.no)
  • Though genome-wide association studies (GWAS) are good at identifying which genetic variants are at play in disease, the large number of associations make determining causation difficult from GWAS data alone. (sanger.ac.uk)
  • This article investigates the impact of the fuel mix structure in power generation portfolios on expected stock returns for major European power companies. (repec.org)
  • The NORA Healthy Work Design and Well-being Cross-sector Council works with partners to improve the design of work, work environments, and management practices in order to advance worker safety, health, and well-being. (cdc.gov)
  • It lays the groundwork for understanding the modulation of gene expression in these cells, providing valuable data on which to build future studies and pursue new treatments. (sanger.ac.uk)
  • Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. (cancerindex.org)
  • H. pylori cytotoxin associated antigen A (CagA) plays a crucial role in the development of gastric cancer. (bvsalud.org)
  • We believe that we achieved a satisfactory translation and cross-cultural adaptation. (uib.no)
  • Studies of model systems. (lu.se)
  • This study advances our knowledge of transcriptional MRs potentially involved in HCC development and progression that may be targeted by specific interventions. (aging-us.com)
  • This study investigated the frequency with which women employed in U.S.-based nursing homes entered and exited unpaid caregiving roles for children (double-duty-child caregivers), adults (double-duty-elder caregivers), or both (triple-duty caregivers), as well as examined how combinations of and changes in these caregiving roles related to cross-sectional and longitudinal sleep patterns. (cdc.gov)
  • A multinational study by WHO on the main reason. (who.int)