AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social Phenomena
Salvia miltiorrhizaSalviaDiterpenes, AbietaneDrugs, Chinese HerbalPhenanthrenesDepsidesSalvia officinalisLamiaceaeMedicine, Chinese TraditionalPlant ExtractsPhytotherapyBenzofuransPlant RootsCinnamatesBenzaldehydesPlants, MedicinalPanax notoginsengCaffeic AcidsPhenanthrolinesPlant PreparationsGenome, ChloroplastCatecholsDiterpenes, Clerodane
DanshenBungeMedicinalSalvianolic acidTanshinonesWidelyHerbMechanismCurcuminRootsWarfarinDihydrotanshinoneMedicinesEffectsRolesHerbalCirculatoryTraditionalPharmacologyComponentsChinesePotassiumMolecularClinical studyMainFoundActiveShownAbstractWorkLigamentInvestigateEffectHumanGeneLargeImproveCellResearchRESULTSActivityPlantPlantsAnimalBodyJournalHigh
Danshen7
  • pinyin: dānshēn), also known as red sage, redroot sage, Chinese sage, or danshen, is a perennial plant in the genus Salvia, highly valued for its roots in traditional Chinese medicine. (wikipedia.org)
  • Meta-analyses of oral and injectable forms of danshen in people with angina concluded that the effects of the treatment were inconclusive because the studies were low in quality and the conclusions were not based on strong evidence. (wikipedia.org)
  • Danshen , belongs to the Lamiaceae family , and its scientific name is Salvia miltiorrhiza Bunge. (bvsalud.org)
  • team found herbs like DanShen ( Salvia miltiorrhiza , aka Chinese Salvia or Red Sage) and GuaLou ( Trichosanthis krilowii ) "have profound nitric oxide bioactivity primarily through the enhancement of nitric oxide in the inner walls of blood vessels, but also through their ability to convert nitrite and nitrate into nitric oxide. (holisticprimarycare.net)
  • AIM: To detect the contents of four active components of Salvia miltiorrhiza in various commercially available danshen crude drugs and preparations. (hku.hk)
  • RESULTS: There were great variations in the amount of the four active ingredients in the commercially available danshen crude drugs and drug preparations in this study. (hku.hk)
  • The research had determined that Salvia miltiorrhiza, known commonly as Danshen or Chinese sage, contains active compounds similar to those developed for modern drugs used to treat Alzheimer's Disease. (naturalnews.com)
Bunge3
  • Salvia miltiorrhiza Bunge is a valuable medicinal plant that prevents and treats cardiovascular and cerebrovascular diseases . (bvsalud.org)
  • Salvia miltiorrhiza (SM) Bunge which is a Chinese herb widely used for the treatment of cardiovascular disorders contains a potent antioxidant, Salvianolic acid B. To determine whether the antioxidant affects vascular apoptosis, the present study examined the frequency of apoptotic cell death in atherosclerotic plaques and in restenotic lesions of cholesterol-fed rabbits. (tmu.edu.tw)
  • Comparative Study on the Bisexual Flower and Unisexual Male Flower of Xanthoceras sorbifolia Bunge [J]. Bulletin of Botanical Research, 2014, 34(1): 85-94. (nefu.edu.cn)
Medicinal4
  • Method] The stereoscopic planting pattern with eight cultivars of medicinal plants and three cultivars of kemel-used apricot was adopted to study the effect of different planting pattems on the growth, flowering, fruiting, disease and pest injury as well as the yield of the medicinal plants, [Result] To the same apricot species, Salvia miltiorrhiza Bge. (atlantis-press.com)
  • Medicinal plants used among pregnant women in a tertiary teaching hospital in Jimma, Ethiopia: a cross-sectional study. (pulsus.com)
  • Salvia miltiorrhiza is a common Chinese herb in China, and the main medicinal parts of Salvia miltiorrhiza is the dry rhizome. (diureticspill.com)
  • The Medicinal Plant Research Centre (MPRC) of England recently conducted studies at Newcastle and Northumbria Universities with sage oil herb pills against placebo pills. (naturalnews.com)
Salvianolic acid1
  • Chemical compounds isolated from Salvia miltiorrhiza include salvianolic acid (or salvianolic acid B), dihydrotanshinone, miltirone, tanshinone I, and tanshinone IIA. (wikipedia.org)
Tanshinones2
  • Nearly 30% of photosynthesis products of plants are used to synthesize root compounds, there is evidence that root compounds regulate and significantly affect the root microbiome Tanshinones are the main hydrophobic components in Salvia miltiorrhiza. (bvsalud.org)
  • In order to study whether these compounds can regulate the root-associated microbiomes of S. miltiorrhiza, our study first identified a white root S. miltiorrhiza(BG) which contains little tanshinones. (bvsalud.org)
Widely3
  • S. miltiorrhiza is a deciduous perennial with branching stems that are 30 to 60 cm (0.98 to 1.97 ft) tall, with widely spaced leaves that are both simple and divided. (wikipedia.org)
  • Tanshinone IIA (Tan IIA) is one of the main natural active ingredients purified from Salvia miltiorrhiza radix , which has been widely used in clinical practice for the prevention of psoriasis, atopic dermatitis, and other inflammation-related disorders. (hindawi.com)
  • Salvia is widely used in TCM prescriptions. (walls-work.org)
Herb3
  • In summary, herb-warfarin interaction, especially the clinical effects of herbs on warfarin therapy should be further investigated through multicenter studies with larger sample sizes. (hindawi.com)
  • In absence of good evidence, speculation has taken its place, and poor quality of available information in turn restricts future study of herb-warfarin interaction. (hindawi.com)
  • The technical name for this herb is Salvia officinalis, and this Latin label is derived from the word salvia, which means to be saved. (naturalnews.com)
Mechanism5
  • Although, most of these studies have focused on treatment of tumors, the effects and mechanism of action in keratinocytes are still poorly understood. (hindawi.com)
  • Altogether, this study identifies a potential application of metformin in sensitizing AML cells to chemotherapy and unveils a novel mechanism by which metformin executes such effect via blocking the mitochondrial transfer from stromal cells to AML cells. (biomed.news)
  • utilized a network pharmacology strategy to know the anti-inflammatory mechanism of phytochemicals from Salvia miltiorrhiza (roots) [43]. (bet-bromodomain.com)
  • There is a wide variation in the number of carpel in P. rockii , but the molecular mechanism of the variation has rarely been studied. (biomedcentral.com)
  • In this study, we investigated the mechanism of the effect of direct "Sanse powder" application for the treatment of knee osteoarthritis (KOA) in rats by using lipidomics. (biomedcentral.com)
Curcumin1
  • Animal and in vitro studies suggest that cognitive enhancing benefits of curcumin are based on multiple mechanisms of action including inhibition of lipid peroxidation, scavenging reactive oxygen species (ROS), and reactive nitrogen species, inhibition of NF-kB activation, and its anti-inflammatory actions. (iherb.com)
Roots1
  • The hairy roots of Salvia miltiorrhiza were subject to proteomic analysis to identify lysine succinylation sites using affinity purification and HPLC -MS/MS in this investigation. (bvsalud.org)
Warfarin1
  • The potency shown in clinical use boosts the studies on the mechanisms of warfarin anticoagulation. (hindawi.com)
Dihydrotanshinone2
  • This study aimed to evaluate the effects of 15,16-dihydrotanshinone I on FLT3-ITD acute myeloid leukemia cells. (banglajol.info)
  • This study suggests that dihydrotanshinone I inhibits MV4-11 proliferation by apoptosis via antagonizing FLT3-ITD/STAT5/Mcl-1 path-way, which might provide a novel therapy for acute myeloid leukemia. (banglajol.info)
Medicines3
  • Alone or combined with other Chinese herbal medicines, Salvia miltiorrhiza has been used in China and, to a lesser extent, in other countries as a treatment for various cardiovascular and cerebrovascular diseases. (wikipedia.org)
  • Many traditional Chinese medicines have been extensively studied in China during the last 10-20 years using the current tools and intellectual frameworks of modern Western science. (anti-agingfirewalls.com)
  • In general, those medicines that have been studied are ones known to be efficacious in traditional Chinese practices but are not used in Western medical clinical practices. (anti-agingfirewalls.com)
Effects10
  • This study examined the effects of a 750 mg/day dose of TendoGuard on joint pain and range of motion in 20 men and women aged 45 to 75 with a history of a knee disorder. (nutritionaloutlook.com)
  • Sodium tanshinone IIA sulfonate is an effective monomer extracted from the traditional Chinese medicine Salvia miltiorrhiza ( S. miltiorrhiza ), it has the effects of scavenging oxygen free radicals, placing myocardial damage, and inhibiting the function of white blood cells, placing myocardial infarction, and ischemic heart disease, pulmonary hypertension, and chronic obstructive pulmonary disease often require its use[ 4 - 6 ]. (ijpsonline.com)
  • The toxicity of Salvia miltiorrhiza and its preparation is relatively small, but there are also reports of side effects in clinical application. (diureticspill.com)
  • The objective of the study was to detect the effects of different inotropes on the hemodynamics of patients who developed low cardiac output. (pubmed.pro)
  • The aim of this study was to investigate the potential of cryptotanshinone (CPT), naringenin, and their combination in modulating the immune response towards Th1 cells and the involvement of JAK2/STAT3 signaling pathway in these effects. (biomedcentral.com)
  • 17- "Beneficial effects of Salvia miltiorrhiza in the healing of burn wounds: an experimental study in rats. (drsevgikurt.com)
  • Within this study, we employed a network pharmacology-based strategy to predict potential targets and mechanisms of action of your anti-obesity effects of p-synephrine and hispidulin. (bet-bromodomain.com)
  • It also features Salvia miltiorrhiza , grains of paradise, guayusa and L-theanine for powerful sensory effects! (tigerfitness.com)
  • Many herbs used in Chinese medicine have been investigated alone and in different combinations for their potential beneficial effects on symptoms of AD and VaD, including Ginkgo biloba , Huperzia serrata , Curcuma longa , Panax ginseng , Panax notoginseng, Bacopa monnieri , Salvia miltiorrhiza, Crocus sativus , and Camellia sinensis. (iherb.com)
  • Many studies have shown significant treatment effects of traditional Chinese medicine on KOA. (biomedcentral.com)
Roles2
  • Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear. (biomedcentral.com)
  • Cell proliferation, migration and invasion assay were used to study the roles of HK1 regulation by PPP2R3A. (bvsalud.org)
Herbal1
  • Below is a concise review of studies on single Chinese herbs and complex Chinese herbal formulas being investigated for their potential cognitive enhancing benefits in healthy adults and individuals with dementia. (iherb.com)
Circulatory2
  • Dr. Tang wanted to study ancient formulas used to treat heart and circulatory problems. (holisticprimarycare.net)
  • The phenomenon of lack of potassium will produce certain damage on the human urinary system, circulatory system, nervous system, the study found that Salvia miltiorrhiza contains a large number of potassium elements, this ingredient can effectively improve the body's ability to withstand hypoxia, effectively improve the health condition of the body. (diureticspill.com)
Traditional3
  • Our findings provide the molecular mechanisms by which Tan IIA can be used to treat psoriasis and support the traditional use of Salvia miltiorrhiza Bungee (Labiatae) for psoriasis and related skin diseases. (hindawi.com)
  • In the use of Salvia miltiorrhiza, although it can also be used alone, with other traditional Chinese medicine can achieve a better therapeutic effect. (diureticspill.com)
  • Our integrative approach could be applied to other multi-component traditional Chinese medicine investigation where ample clinical data are accumulated but advanced mechanistic studies are lacking. (pubmed.pro)
Pharmacology2
  • Numerous current studies have applied network pharmacology to investigate the mechanisms of action of compounds from natural merchandise. (bet-bromodomain.com)
  • As such, network pharmacology plays an important part in overcoming the limitations of studies on conventional natural goods by supplying a brand new approach to predict the active ingredients, possible targets, and mechanisms of action. (bet-bromodomain.com)
Components1
  • The present study aimed to evaluate the efficacy of SXSM on bradycardia and to identify the possible active components and their pharmacological targets for this action. (pubmed.pro)
Chinese1
  • Also, the Chinese research appears to be heavily oriented to molecular biology and in-vitro studies, infrequently involves animal experiments, and generally stops short of clinical trials. (anti-agingfirewalls.com)
Potassium1
  • The aim of the present study was to explore the pathogenic role of aberrantly activated potassium channel in Hereditary Gingival Fibromatosis (HGF). (shengsci.com)
Molecular1
  • Molecular studies such as pan-TRK immunostaining, FISH and even next-generation sequencing are needed to confirm the diagnosis. (bvsalud.org)
Clinical study2
  • RESULTS:Meta-analysis of the available clinical study data shows that Shenxian-Shengmai Oral Liquid has a favorable effect for bradycardia. (pubmed.pro)
  • A second key ingredient in TEST HD THERMO has been shown in a separate clinical study to increase free testosterone and decrease estradiol in just 7 days. (tigerfitness.com)
Main1
  • Sanse powder" is the main component of "Yiceng", and our previous studies found that "Yiceng" application alleviated synovial inflammation, relieved pain and improved the cold pain threshold [ 6 , 7 ]. (biomedcentral.com)
Found1
  • A study published in JAMA Network Open in 2019 found that people who are more optimistic about the future have a lower risk of heart disease. (walls-work.org)
Active1
  • In the present study, we report cryo-electron microscopy structures of CI from Sus scrofa in six treatment conditions at a resolution of 2.4-3.5 Å, in which CI structures of each condition can be classified into two biochemical classes (active or deactive), with a notably higher proportion of active CI particles. (biomed.news)
Shown2
  • She also suggests the use of dietary supplements that have been shown in some studies to improve kidney function. (drprincetta.com)
  • TEST HD ® THERMO features the premium branded ingredient KSM-66 ® Ashwagandha, scientifically shown in an 8-week, gold-standard study to support testosterone levels, strength, muscle size and performance. (tigerfitness.com)
Abstract1
  • The exclusion criteria were studies published as an abstract only, crossover studies, and studies with a lack of data on the cardiac index. (pubmed.pro)
Work1
Ligament1
  • The subjects were given the McMurray test for meniscus injury, the Steinmann I and II tests, and the Butler drawer test to assess ligament stability at baseline and on study conclusion. (nutritionaloutlook.com)
Investigate1
  • It was the aim of the present study to investigate whether such a relationship also exists in the periodontium of man. (shengsci.com)
Effect2
Human1
  • Salvia miltiorrhiza has been used for a long time in our country, and it is very helpful to the human body. (diureticspill.com)
Gene2
  • But systematic studies on the gene family have not been reported yet in poplar. (biomedcentral.com)
  • FISH studies confirmed the NTRK3 gene rearrangement in all 3 cases. (bvsalud.org)
Large2
  • Due to the small number of included studies, poor quality of trial design, and substantial heterogeneities, the potential of CHM for AR should be validated in large, multicenter, and well-designed RCTs in the future. (pubmed.pro)
  • Large placebo-controlled studies and meta-analyses of studies that meet strict inclusion criteria for rigor support that G. biloba extract slows the rate of decline in cognition, executive functioning and behavior in individuals diagnosed with AD and VaD. (iherb.com)
Improve2
  • Modern medical research has proved that Salvia miltiorrhiza can effectively improve the activity of superoxide dismutase, enhance the ability of sand organs. (diureticspill.com)
  • After entering the body, Salvia miltiorrhiza can effectively expand the coronary artery, so that the flow in the coronary artery will greatly increase, can effectively expand the size of the surrounding blood vessels, improve the blood circulation in the body, shorten the recovery time of hemoglobin and red blood cells, effectively promote the repair of tissues, reduce local congestion and pain. (diureticspill.com)
Cell1
  • The study has previously revealed that miR-125b faciliates cell migratory ability breast cancer via targeting STARD13 (StAR-related lipid transfer protein 13) [ 20 ]. (biomedcentral.com)
Research3
  • Nitric Oxide (NO) research has yielded 3 Nobel prizes, countless studies, and a lot of insight into the process of vasodilation. (holisticprimarycare.net)
  • Developmental Anatomy of the Floral Nectaries in Salvia deserta Schang[J]. Bulletin of Botanical Research, 2012, 32(6): 641-645. (nefu.edu.cn)
  • Anatomical Study on Leaf of Salvia miltiorrhiza from Different Areas [J]. Bulletin of Botanical Research, 2014, 34(6): 730-735. (nefu.edu.cn)
RESULTS1
  • RESULTS:A total of 1402 patients from 37 trials were included in the study. (pubmed.pro)
Activity2
  • The study authors concluded collagen peptides can reduce knee pain during activity. (nutritionaloutlook.com)
  • And a recent study demonstrates that Tanshinone IIA restrains migratory and invasive ability of cervix carcinoma stem cells by suppressing the transcriptional activity of YAP (Yes-associated protein) [ 11 ]. (biomedcentral.com)
Plant1
  • Our study may provide valuable insights for further investigation on plant succinylation, specifically as a reference point. (bvsalud.org)
Plants1
  • In this study, alfalfa plants were subjected to 150 mM NaCl with or without methyl jasmonate (MeJA). (frontiersin.org)
Animal1
  • She likes animal studies that use the 5/6 nephrectomy model, in which 5/6 of the kidney is removed. (drprincetta.com)
Body1
  • A study published in the European Journal of Clinical Nutrition in 2020 showed that for adults, for every 5 kg (11 lb) increase in body weight, the risk of death from CVD increases by 11 percent, and the risk of coronary heart disease increases by 18 percent. (walls-work.org)
Journal1
  • A study published in the Journal of Hypertension in 2012 showed that for patients with a higher risk of heart disease due to high blood pressure, regular exercise can reduce the risk of death from cardiovascular disease by 16 to 67 percent. (walls-work.org)
High2
  • Oxygen-induced retinopathy was studied in the model group, low-dose group, and high-dose group 30 mg/kg sodium tanshinone IIA sulfonate. (ijpsonline.com)
  • One study claims a success rate as high as 70 percent, while another claims it is as low as 18 percent. (edocr.com)