Study of human protective agents. Medical search. Frequent questions

Projects include establishing new MRI and PET image acquisition and analysis tools that can improve brain tumor patient management (e.g., diagnostics, prognostics, early therapeutic response assessment, radiotherapy, and surgical guidance) and establishing neuroimaging tools to investigate the impact of cancer therapies, and neuro-protective agents, on neuro-health and cognition. (gettinghired.com)
A series of longitudinal and neuro-imaging studies in the elderly have shown that light to moderate wine consumption is neuro-protective although heavy or abusive alcohol consumption is neuro-toxic. (iospress.com)
PQQ's cell signaling activities produce measurable health improvements, especially cardio-protective and neuro-protective benefits. (lifeextension.com)

Our previous work showed that a continuous delivered dose (0.18 microg/cm2) of nFe2O3 induced a neoplastic-like transformation in human primary small airway epithelial cells after 10 weeks exposure, with evidence suggesting that this transformation is related to disruption of iron homeostasis in the exposed cells. (cdc.gov)
Herein, we utilized a sub-chronic exposure model to investigate the potentially protective qualities of an amorphous nano-silica (nSiO2) coating on nFe2O3-induced bio-effects using a human lung bronchial epithelial cell line. (cdc.gov)
In recent years, naturally occurring herbal compounds have gained considerable attention as protective agents for UV exposure. (spandidos-publications.com)
The results of the present study demonstrated that treatment with PF (25, 50, and 100 µM) significantly increased the percentage of viable keratinocytes after UV‑B exposure. (spandidos-publications.com)
Laboratory animal studies as well as occupational epidemiological studies demonstrate that a broad range of chemical agents can increase the vulnerability of subjects to noise exposure. (cdc.gov)
In our studies, laboratory rats were exposed to noise alone, selected chemical agents alone (carbon monoxide, hydrogen cyanide, and acrylonitrile), mixed exposure to chemicals and noise , and no experimental treatment (control). (cdc.gov)
NTP, 2007a,b), and some epidemiologic studies have suggested that long-term exposure to DBPs is associated with an increase in bladder cancer (reviewed in Richardson et al. (nationalacademies.org)
Any applicable exposure limits for individual chemical and physical agents associated with welding (i.e. (cdc.gov)
Data from studies on both humans and animals demonstrate a direct link between exposure to radon progeny and lung cancer. (cdc.gov)
Epidemiologic studies provide a basis for quantitatively estimating human risk at various exposure levels. (cdc.gov)
She uses in vitro model systems to understand the mechanisms of gastrulation, the foremost, crucial and sensitive stage of embryo development, and exposure to teratogens, agents that can cause birth defects. (hawaii.edu)
The aim of the current study is to observe the effect of CSE on biological behavior of EPCs and, further, to search for potential candidate agent in protection of proliferation of EPCs against the damage caused by CSE exposure in vitro . (hindawi.com)
In this study, in attempt to provide fresh information about the impact of CS on proliferation of EPCs to elucidate the pathophysiological mechanisms of the diseases related to CS in cellular level, we assessed the proliferation of EPCs after interfering the cells with a series of concentrations of CSE for various times of exposure in vitro . (hindawi.com)
This study compared the systemic disposition and brain distribution of total and inorganic mercury in infant monkeys following thimerosal exposure with infants exposed to MeHg. (blogspot.com)
The current study indicates that MeHg is not a suitable reference for risk assessment from exposure to thimerosal derived Hg. (blogspot.com)
Evidence is included about assessing exposure, clean-up and prevention, personal protective equipment, health effects, and public health strategies and recommendations. (cdc.gov)
Some clinical studies, including controlled trials, both prospective and ambidirectional in design, indicate an association between any exposure (single or multiple) to anesthesia and surgery at a young age, generally less than 3-4 years, and later behavioral and neurodevelopmental problems. (bvsalud.org)
Although challenging to quantify, recent studies have documented isocyanate and beryllium skin exposure, even with the use of personal protective clothing. (cdc.gov)
Animal studies demonstrate that skin exposure to isocyanates and protein allergens is highly effective at inducing sensitization, with subsequent inhalation challenge eliciting asthmatic responses. (cdc.gov)
Limited clinical studies suggest a similar role for human skin exposure to certain sensitizing agents. (cdc.gov)
With generally reduced that skin may be an important site of exposure and initial occupational exposures to the traditional inorganic dusts sensitization for certain occupational and environmental such as asbestos, silica and coal dust, and the expanding use agents. (cdc.gov)
Exposure to isocyanates and to beryllium, rather than ease, two of the more commonly diagnosed occupational occurring as single agents at constant levels, typically lung diseases, share several features that have hampered occur as mixed or variable exposures, complicating recognition and prevention. (cdc.gov)
Experimentally, infiltration of HRIG at the site of exposure is more protective than IM administration. (medscape.com)
NIOSH engineers have studied control of respirable silica dust in nearly a dozen industries---in one example, employee exposure to respirable silica dust was reduced approximately 87% after a china manufacturing plant implemented its dust-control recommendations. (cdc.gov)
Systemic effects occur in animals after oral exposure, but have not been reported in humans. (cdc.gov)

Khader's research focuses on the interaction of the host immune system with the causal agent for tuberculosis, Mycobacterium tuberculosis . (uchicago.edu)
Protective immunity to Mycobacterium tuberculosis (Mtb) -the causative agent of tuberculosis (TB)-is not fully understood but involves immune responses within the pulmonary airways which can lead to exacerbated inflammation and immune pathology. (frontiersin.org)
In temperate southeastern Australia over the past two decades there has been a marked progressive increase in human cases of Buruli ulcer, an infection of subcutaneous tissue caused by Mycobacterium ulcerans . (biorxiv.org)
She studies mechanisms employed by the deadly Mycobacterium tuberculosis pathogen to survive severe zinc depletion in the host, a necessary step for disease transmission. (hawaii.edu)

The present study evaluated the protective effects of PF on UV‑induced skin damage in vitro, and demonstrated that the effects were mediated via the ROS‑p38‑p53 pathway. (spandidos-publications.com)
Scientific Methods: In vitro growth inhibition assays were completed with AHCC alone and in combination with PLD in panel of human cancer cell lines and findings confirmed in vivo in an ovarian cancer xenograft mouse model. (researchgate.net)

The authors also argue that memory B and T cell responses are long-lived in the absence of antigen, but they are modulated and influenced by other infections and that memory B and T cells can either provide protective immunity or contribute to immunopathology on infection with homologous or heterologous viruses. (scielo.br)
Early studies revealed that animals deprived of PQQ exhibit signs of accelerated aging in the form of elevated plasma glucose concentrations, impaired oxygen metabolism, stunted growth, compromised immunity, impaired reproductive capability, reduced numbers and survival rate of offspring, and a decrease in energy-producing mitochondria in their tissue. (lifeextension.com)
These agents promote immunity by inducing an active immune response. (medscape.com)

Results showed that in cultured human-derived retinal pigment epithelial ARPE-19 cells , the extract of Chlorella zofingiensis and its nutritional ingredient astaxanthin exhibited significant inhibitory effects on the formation of endogenous N ε -carboxymethyllysine (CML), a key AGE representative, through the suppression of intracellular oxidative stress. (rsc.org)
AIM OF THE STUDY: This study aimed to investigate the effect and the uc.173-related mechanism of Lico A on intestinal epithelial renewal. (bvsalud.org)
CONCLUSION: Results in this paper suggest that targeting T-UCRs may be the novel therapeutic approach for the promotion of epithelial regeneration, and through stimulating the regeneration of intestinal mucosa, Lico A may become a new therapeutic agent for the maintenance of intestinal epithelial integrity. (bvsalud.org)

Pretreatment of cells with N-acetyl-L-cysteine (NAC), an agent known to counteract oxidative stress, attenuates the cellular p53 response to UV ( 4 ). (spandidos-publications.com)
Specific chemical agents were selected based both upon their common use in occupational settings and their potential to produce oxidative stress. (cdc.gov)

Following a bout of "winter vomiting" at an elementary school in Norwalk, Ohio in 1968, Norwalk virus was the first of the noroviruses to be identified as the causative agent behind an outbreak of gastroenteritis. (bcm.edu)

Studies out of Fox Chase Cancer Center have linked this protective effect to the presence of human chorionic gonadotropin (hCG), a hormone produced by the placenta to maintain the early stages of pregnancy. (weeksmd.com)

These findings suggest that human IBD and CRC may be amenable to cannabinoid treatment. (nature.com)
Findings will be disseminated to the community of the study sites, with academic bodies and policymakers. (bmj.com)
The findings built on earlier ones from the MORGEN study [7]. (wind-watch.org)
The findings could lead to expanded use of dodecenal as a tasteless food additive to prevent foodborne illness, perhaps as a protective coating for meats in processing plants, or even as a general purpose disinfectant to be used in cleaning and hand washing, Kubo says. (eurekalert.org)

Her group leverages fundamental discoveries in tuberculosis research to develop novel approaches to vaccine development, diagnostics and biomarkers, and defining new treatments for tuberculosis in humans. (uchicago.edu)
Only 5% to 10% of immunocompetent humans are susceptible to tuberculosis, and over 85% of them develop the disease exclusively in the lungs. (scielo.br)
In a very interesting issue, R.J. NORTH & Y-J. JUNG first argue that mouse tuberculosis and tuberculosis in guinea pig and rabbit are models of tuberculosis in susceptible humans. (scielo.br)

Neutrophils, though increasingly linked to the development of inflammatory disorders, have been less well studied in relation to TB-induced lung pathology. (frontiersin.org)

The data gleaned from multiple experiments demonstrate that chemical agents capable of interfering with intrinsic antioxidant pathways do, in fact, increase noise -induced hearing loss and produce extensive outer hair cell death. (cdc.gov)
In humans, these pigments act as protective agents against oxidative damage[ 9 ] and demonstrate pro-vitamin A function that protects from lifestyle-related disorders such as cardiovascular disease and age-related muscular degeneration[ 10 ]. (ijpsonline.com)
Conclusions: These results demonstrate that the endogenous protective mechanisms within the myocardium may be amenable to therapeutic manipulation. (ucl.ac.uk)

Reducing exposures to potentially carcinogenic substances in drinking water from groundwater sources seems to be a logical, health-protective action, even if the actual or perceived risk from the contaminants is small. (nationalacademies.org)

In the present study, for the first time, protective effects of three microalgal strains, including their extracts and active compounds, against both endogenous and exogenous AGEs in cell -based models were investigated. (rsc.org)
Hence the potential for exploiting the endogenous protective mechanisms within the myocardium is of prime clinical importance. (ucl.ac.uk)

A systematic review of health behaviours which maintain healthy cognitive function suggests that the consumption of fish and vegetables [ 10, 11 ], moderate physical activity and moderate alcohol consumption tend to be protective against cognitive decline and dementia [ 12, 13 ]. (iospress.com)
A wealth of studies now confirm that PQQ's cell-signaling activity translates into substantial protection against degenerative and age-related conditions, such as mitochondrial dysfunction, 1 heart degeneration, 18-20 brain injury, and cognitive decline. (lifeextension.com)
21-40 As one example, research shows that 20 mg of PQQ daily may reverse age-related cognitive decline in aging humans! (lifeextension.com)

NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)

A human, intraoral, demineralization/remineralization model was used to evaluate various between-meal snack foods. (dentalcare.com)
A clinical study to evaluate of the combination of AHCC plus PLD in the treatment of ovarian cancer is being pursued. (researchgate.net)
In some instances drugs with known antioxidant potential were included to evaluate their protective effects. (cdc.gov)
CRADLE was the first industry-sponsored study to evaluate certolizumab pegol (CZP) concentrations in human breast milk and estimate average daily infant dose (ADID) of maternal CZP. (bmj.com)
The objective of this study was to evaluate the ability of milk to reduce the erosion caused by orange juice in enamel. (bvsalud.org)

Hutterite dust was not protective against ovalbumin-induced allergic inflammation. (medscape.com)

The complexity of trade-offs from substitutions can be illustrated with the case of contamination of potable ground water sources with pesticides or industrial chemicals shown to be carcinogenic in experimental animals or humans. (nationalacademies.org)

Such research may provide a novel preventive and therapeutic approach for diabetic retinopathy, because natural products may have few side effects and are safe for human consumption compared with synthetic compounds. (rsc.org)
In recent years, many protective effects of NR have been reported, including anti-aging, prevention of hearing loss, helping in weight loss, and anti-cancer effects, etc. (databasefootball.com)
Extracts of peony root have previously been shown to exert protective effects against UV-induced DNA damage and facial wrinkles in human skin ( 16 ). (spandidos-publications.com)
The ratio of arachidonic acid (AA) to very long-chain n-3 PUFAs (EPA and DHA) in diets of human beings appears to be an important factor that dictates the anti-inflammatory effects of fish oils," the researchers write. (news-medical.net)
The article notes that "there is a controversy among scientists in this field as to the importance of arachidonic acid or omega-6:omega-3 ratios vs. the concentration of long-chain omega-3 alone with regard to their effects in human biology. (news-medical.net)
Indeed, a study in Texas, USA reported that the number of years lived with chronic TB disability accounts for 75% of non-fatal health effects of TB ( 11 ). (frontiersin.org)
Protective Effects of Gynostemma pentaphyllum (var. (nih.gov)
The data collected in this study on the effects of GP in in vivo models may help integrate the therapeutic strategies of inflammatory-based disorders. (nih.gov)
The ability to replicate the naturally protective effects of pregnancy against breast cancer will hold a significant public health value," says Vanegas. (weeksmd.com)
The animals that received hCG, but still developed breast cancer did so much later than the control group, which further demonstrates the protective effects of hCG," Vanegas says. (weeksmd.com)
While we don't foresee side effects among humans in using hCG, it is helpful to know that even smaller doses confer benefits on breast tissue. (weeksmd.com)
The cardioprotective effects of angiotensin converting enzyme inhibitors were studied in a superfused isometrically contracting human atrial trabeculae model. (ucl.ac.uk)
Furthermore, in a human atrial model of ischaemia, angiotensin converting enzyme inhibitors exert cardioprotective effects, possibly via B2 bradykinin receptors. (ucl.ac.uk)
Efficacious drug deposition in the target site and operated activation of therapeutic and imaging agents reduce treatment time, while avoiding adverse damage and side effects resulting from systemic administration. (nature.com)
If this is confirmed by additional experiments, it will provide a promising pathway of intervention against B[a]P, using ASP or other agents with fewer toxic effects. (bvsalud.org)
The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. (justia.com)
Because chemotherapy affects cell division, both normal and cancerous cells are susceptible to the cytotoxic effects of chemotherapeutic agents. (justia.com)
AIHA ERPG-2 (maximum airborne concentration below which it is believed that nearly all persons could be exposed for up to 1 hour without experiencing or developing irreversible or other serious health effects or symptoms that could impair their abilities to take protective action) = 10 ppm. (cdc.gov)
To investigate the suspicion that the house dust was in itself the immune-modifying agent, the investigators compared the effects of Amish vs Hutterite house dust in a classic ovalbumin mouse model of allergic asthma . (medscape.com)

Using a traditional approach this study provides pre-clinical data to support the benefits previously observed and reported in the clinical setting and supports future endeavors to integrate AHCC into standard of care to be given with chemotherapy. (researchgate.net)
PURPOSE: Chemotherapy-induced peripheral neurotoxicity (CIPN) is a highly prevalent, dose-limiting, costly, and tough-to-treat adverse effect of several chemotherapy agents, presenting as sensory and motor dysfunction in the distal extremities. (bvsalud.org)
It also has severe limitations on the dosage of chemotherapeutic agents that can be administered to a patient, thus, limiting the effective range of chemotherapy. (justia.com)
By making normal cells more resistant to chemotherapeutic agents, a patient's tolerance for cytotoxicity is improved, which, in turn, also improves the effectiveness of chemotherapy. (justia.com)
One method comprises starving the subject for 24-60 (e.g., 48) hours and administering to the subject a chemotherapy agent. (justia.com)
Another method of the invention comprises administering a cell growth inhibitor to the subject and administering to the subject a chemotherapy agent. (justia.com)
Another method of the invention comprises reducing the caloric intake or the glucose intake by the subject and administering to the subject a chemotherapy agent. (justia.com)
In another aspect, the invention features methods of contacting a cancer cell with a chemotherapy agent and methods of increasing resistance of a non-cancer cell to a chemotherapy agent. (justia.com)

Nipah virus (NiV) is a zoonotic pathogen that causes high case-fatality rates (CFRs) in humans. (cdc.gov)
NiV is categorized as a Biosafety Level 4 (BSL-4) pathogen because of the substantial illness and death it causes and the lack of approved vaccines and therapeutic drugs for human use. (cdc.gov)
She studies the complex host-pathogen interaction mechanisms by which the bacterium escapes a protective casing of immune cells where it can be constrained for long periods in a latent state, and then spreads as a pathogenic organism throughout the host environment. (uchicago.edu)
The caliciviruses consist of four groups, of which the noroviruses are the most important human pathogen . (bcm.edu)

[ 5 ] Rabies variants have been detected in cougars and skunks in Mexico, which was declared free of human rabies from dogs in 2021. (medscape.com)

Over the past 20 years, hundreds of preclinical studies of the developing central nervous system have been published concluding that the common Î³-aminobutryic acid and N-methyl-d-aspartate binding anesthetic agents cause neuroapoptosis and other forms of neurodegeneration. (bvsalud.org)

Ticks (Acari: Ixodidae and Argasidae) transmit multiple and diverse pathogens (including bacteria, protozoa, and viruses), which cause a wide range of human and animal diseases, including rickettsial diseases, caused by bacteria in the order Rickettsiales. (cdc.gov)
Awareness, diagnosis, and control of tickborne rickettsial diseases are most effectively addressed by considering the intersecting components of human, animal, and environmental health that collectively form the foundation of One Health ( 1 ), an approach that integrates expertise from multiple disciplines and facilitates understanding of these complex zoonoses. (cdc.gov)
Tickborne rickettsial diseases in humans often share similar clinical features yet are epidemiologically and etiologically distinct. (cdc.gov)
In addition, the in-depth study on genome-wide epigenetics gained more comprehensive understandings of epigenome in many diseases. (hindawi.com)

Recently, NiV B in African green monkeys resulted in a more severe and lethal disease than NiV M . No NiV vaccines or treatments are licensed for human use. (cdc.gov)
This optimism is built on recently published studies demonstrating the efficacy of mRNA vaccines in combatting several types of cancer and infectious pathogens where conventional vaccine platforms may fail to induce protective immune responses. (researchgate.net)

Further protective roles of NR and the mechanisms are still under investigation right now. (databasefootball.com)

Although NK cells play important roles in host defense against various infectious agents, they are critical in host defense against viral infections. (scielo.br)
Low-income and disadvantaged groups are generally more exposed to avoidable risk factors such as environmental carcinogens, alcohol, infectious agents, and tobacco use. (who.int)
Infectious agents are responsible for almost 25% of cancer deaths in the developing world and 6% in industrialized countries. (who.int)

Until recently, the treatment of cancer has been largely focused on the development of therapeutic agents or techniques that kill cancer cells. (justia.com)

These microalgae, therefore, might be regarded as beneficial foods and preventive agent choices for patients with diabetic retinopathy. (rsc.org)
In order to translate our finding into humans, a clinical trial with hCG as a preventive agent against breast cancer, is already ongoing in pre-menopausal women with no previous pregnancy. (weeksmd.com)

Working with and through the National Toxicology Program, NIOSH is conducting research on the irritant and allergenic properties of MWFs and is also studying their potential for carcinogenicity. (cdc.gov)

A tyrosine kinase inhibitor known to induce stress proteins in non cardiac cells was studied in detail. (ucl.ac.uk)

For example, primary prevention, early detection and palliative care are often neglected in favour of treatment-oriented approaches, even in cases where these approaches are not cost-effective and cause unnecessary human suffering. (who.int)

Given predictions that these devices will be in short supply if a pandemic strikes in the near future, the U.S. Department of Health and Human Services asked the Institute of Medicine of the National Academies to investigate the potential for reuse of disposable respirators or masks. (sciencedaily.com)
AIM OF THE STUDY: To investigate the anti-infectious constituents of A. euchroma based on NA inhibition. (bvsalud.org)

1991. Alcohol, smoking, and occupational factors in cancer of the larynx: A case control study. (cdc.gov)
Keywords Cold weather studies Cold weather Aerosols Alaska Artic regions Army operation CB agents Decontamination Environmental tests Freezing Hazards Human factors Ice Temperature meteorology Nuclear weapons Polar regions Protective clothing Sampling methods Snow Visibility Water Wind Winter. (dtic.mil)
If the diet is balanced in such a way that the host protective factors (saliva) and fluoride can overcome the bacterial acid challenge, no net demineralization occurs. (dentalcare.com)
This work includes studies of how people's perceptions of sleep duration and disruption are related to objective sleep measures, studies of how social factors such as social connectedness and loneliness relate to measured and perceived sleep, and studies of how both sleep perceptions and objective measures are associated with health outcomes, including coronary artery disease, obesity, mortality, cortisol levels, and sensory perception. (uchicago.edu)
2 Studies that have used information collected during military service suggest that occupational factors explain 25% of apparently new cases. (bmj.com)
Adequate sleep, defined as at least seven hours, was a protective factor which augmented the benefits conferred by the absence of four traditional cardiovascular risk factors. (wind-watch.org)
The competitive program supports junior faculty from U.S. institutions who study how social and environmental factors influence health disparities in under-resourced communities. (nih.gov)
Factors that impair skin barrier function, such as trauma, may promote sensitization to such agents. (cdc.gov)

Human-to-human rabies virus transmission via saliva is theoretically possible. (medscape.com)

The study, which appeared in PLOS Pathogens , found strong genetic evidence that three tree species-Canary Island pine, Pohutukawa, and American sweetgum-can serve as environmental hosts and sources of Cryptococcus, which encompasses a number of species including C. gattii and causes life-threatening infections of the lungs and brain that are responsible for one third of all AIDS-related deaths. (hivplusmag.com)
The National Institute of Environmental Health Sciences (NIEHS) is expanding and accelerating its contributions to scientific knowledge of human health and the environment, and to the health and well-being of people everywhere. (nih.gov)

Bats being small, furry, and potentially irresistible to curious humans, children should be taught not to handle a downed bat. (medscape.com)
Any potential agent which induces a state of enhanced resistance to ischaemia warrants investigation as it may potentially lead to the development of novel therapeutic approaches to cardioprotection in clinical practise. (ucl.ac.uk)

One approach to protecting human skin against UV radiation is the use of antioxidants. (spandidos-publications.com)

Industrial Relevance: This study presents an example of the successful integration of a well- known herbal supplement, AHCC, with traditional western medicine cytotoxic agent, pegylated liposomal doxorubicin, for the treatment of recurrent ovarian cancer. (researchgate.net)

To test new treatments, animal models which reflect human disease are essential. (carnegie-trust.org)
The hCG hormone is an FDA-approved agent frequently used for fertility treatments. (weeksmd.com)

He is working to hack the immune system to uncover protective responses to emerging infectious viruses. (hawaii.edu)

Our study is now only a test in murine, the exact effect on the human body needs further exploration. (databasefootball.com)
Murine studies have cyanates and other chemicals, with highly variable vola- demonstrated that dose, route and timing of isocyanate tility, mass, solubility and isocyanate content [5] . (cdc.gov)

These data show protective efficacy against a stringent and relevant NiV B model of human infection. (cdc.gov)

Human coronaviruses were discovered in the 1960s by researchers studying the etiology of upper respiratory infections (URIs) in children and young adults. (thieme-connect.com)
Researchers have identified a compound in cilantro, a key flavor component of salsa and a variety of other dishes, that kills harmful Salmonella bacteria and shows promise as a safe, natural food additive that could help prevent foodborne illness, according to a joint study by U.S. and Mexican researchers. (eurekalert.org)
Although previous studies by the researchers showed that salsa has antibacterial activity, this new study represents the first time that they have isolated any of the antibacterial compounds from it. (eurekalert.org)
The researchers say that their lab does not plan to market dodecenal as a bacteria fighter or test it further to see if it works in humans. (eurekalert.org)

We attempted a number of different methods to breakdown the protective barrier around the nerve in the leg but were unable to overcome the inability for the disease-causing agents to reach our site of injury, despite promising pilot data. (carnegie-trust.org)
Methods: Two routes to myocardial protection were studied: The potential role for up regulating stress proteins in order to protect the myocardium was examined in an isolated rat neonatal cardiomyocyte model. (ucl.ac.uk)
Methods CRADLE ( NCT02154425 ) was a pharmacokinetic study of lactating mothers receiving CZP. (bmj.com)

All of these studies share the weakness that they are 'observational' as opposed to 'experimental' and, as such, their results do not constitute 'proof. (wind-watch.org)
We now have the evidence of an experimental study carried out in human volunteers which shows that the expression of a large range of genes is affected by sleep deprivation of fairly short duration [10]. (wind-watch.org)

This study demonstrates that very low-levels of Thimerosal can contribute to immune system disregulation. (blogspot.com)

We found that NR is a good agent in the protection of liver fat accumulation induced by alcohol. (databasefootball.com)
That is, when you have a binge alcohol drinking, taking a supplement of NR might have some protective effect on the liver. (databasefootball.com)
Heat-treated and cold alcohol-fractionated immunoglobulin is derived from pooled human plasma from individuals immunized with human diploid cell rabies vaccine. (medscape.com)
Crotonaldehyde has also been used as a warning agent in fuel gases, in the preparation of rubber accelerators, in leather tanning, as an alcohol denaturant, and as a stabilizer for tetraethyl-lead. (cdc.gov)

The mechanism study in silicon revealed that these natural compounds possessed absolutely different binding modes on the bacterial and viral NAs. (bvsalud.org)

Standard precautions are recommended in the care of patients with rabies in healthcare settings, including use of personal protective equipment during activities that may pose a risk for salivary contamination of mucosa or break in the skin. (medscape.com)

Guidelines are also provided for respiratory protection and protective clothing. (cdc.gov)

Standard treatment for IBD includes anti-inflammatory agents, such as aminosalicylic acid as well as immunomodulators, steroids, and biological agents. (nature.com)

To study further the function of SIRT1 in the protective effect of NR on the liver, we applied gene-knockdown technology to knockdown SIRT1 gene in liver cells and we found that NR's protective effect on liver steatosis disappeared without SIRT1 expression. (databasefootball.com)
In this study, we investigated the potential role protective of ASTA, an antioxidant marine carotenoid, in restoring physiological conditions in U937 cells stimulated with LPS (10 µg/ml). (nih.gov)
In the B cell system protective memory is mediated by plasma cells that secrete antibodies, whereas reactive memory is mediated by memory B cells that proliferate and differentiate to plasma cells in response to secondary antigenic stimulation. (scielo.br)
Recent studies indicate that memory T lymphocytes contain distinct populations of central memory (T CM cells) and effector memory (T EM ) cells characterized by distinct homing capacity and effector function. (scielo.br)
review the heterogeneity of the current models for memory T cells generation and maintenance in humans and mice. (scielo.br)
This study explored the miRNA-mRNA network in the B[a]P-induced neurotoxicity in mice and HT22 cells and the intervention of aspirin (ASP). (bvsalud.org)
The present invention provides a novel approach to cancer therapy by providing a method to differentially enhance the resistance of normal cells to chemotherapeutic agents, thereby, improving the effectiveness of chemotherapeutic agents in killing cancerous cells. (justia.com)
The study found differences in proportions and gene-expression profiles of peripheral blood immune cells and in the genes involved in innate immune responses to microbes. (medscape.com)

In addition, the Secret Service successfully secured a number of protective stops during the President's recent eight-day foreign trip to Saudi Arabia, Israel, Belgium, and Italy. (dhs.gov)
They cite numerous studies, including a recent one that predicts "that changes in arachidonic acid to EPA or DHA ratios shift the balance from pro-inflammatory [agents] to protective chemical mediators " which are proposed to play a pivotal role in resolving inflammatory response in the body. (news-medical.net)
A recent cohort study showed that subjects with a history of fully treated active TB (ATB) lost 3.6 years on average of disability-adjusted life expectancy compared to subjects with latent TB infection (LTBI) who did not progress to the active state ( 12 ). (frontiersin.org)
Additionally, a recent retrospective study reveals the negative effect of drug-resistance and disease recurrence on PIAT ( 15 ). (frontiersin.org)
Istodax (generic: romidepsin) successfully "kicked" HIV out of reservoirs in patients in a recent study. (hivplusmag.com)
A recent case-control study conducted around two wind farms in New England has shown [2] that subjects living within 1.4 km of an IWT had worse sleep, were sleepier during the day, and had poorer SF36 Mental Component Scores compared to those living further than 1.4 km away. (wind-watch.org)
Another important, recent study is MORGEN which followed nearly 18,000 Dutch men and women, free of Cardiovascular Disease at baseline, over 10-14 years [8]. (wind-watch.org)

The caliciviruses have been difficult to study due to their inability to grow in a cell culture system and the lack of a good animal model system. (bcm.edu)

19 Duggal et al 20 used a slightly different human model to examine the frequency of carbohydrate consumption with and without fluoride toothpaste. (dentalcare.com)
The consumption of acid food and drink has increased over the last few decades and many studies have related this fact to the increasing prevalence of dental erosion 17,19 . (bvsalud.org)

The study looked at asthma prevalence and the clinical and immunologic characteristics of atopic disease of children in both groups, and assessed the human and mouse model responses to house dust. (medscape.com)

In low-resource settings with a high prevalence of cancers induced by biological agents, special measures are needed to combat these infections. (who.int)

Prior to the past two decades, the four circulating species of coronaviruses associated with human disease were known to be a significant cause of the common cold and other mild URIs. (thieme-connect.com)

The medical journal Intervirology published a clinical study performed in 2009 in which scientists at Golestan University of Medical Sciences and Health Care in Gorgan, Iran used Echinacea purpurea to prevent the spread of the herpes simplex virus to the eyes during the latent stage. (progressivehealth.com)

Caries is a complex biological process which involves an infectious agent (acid-forming bacteria), the host or patient, and the diet (fermentable carbohydrates). (dentalcare.com)

In animal studies, ingestion has led to systemic toxicity. (cdc.gov)

Treatment with PF markedly reduced the production of ROS, and inhibited the activation of p38 and p53 in human keratinocytes, thus suggesting that the ROS‑p38‑p53 pathway has a role in UV‑B‑induced skin damage. (spandidos-publications.com)
Vertebrate animals play an integral role in the life cycle of tick species, whereas humans are incidental hosts. (cdc.gov)
Previous case-control studies, insect field surveys and vector competence studies have suggested a role for mosquitoes in M. ulcerans transmission between possums and humans. (biorxiv.org)
The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (nih.gov)
The fetal hemoglobin may play a protective role against coronavirus in neonates. (thieme-connect.com)
Neuraminidases (NAs) not only play a key role on human health, but also are promising targets for anti-infectious drugs. (bvsalud.org)

Another prospective porous material is zeolite, which shares many of the favorable properties of silica, especially in biomedical applications related to transportation of low molecular weight drugs and imaging agents. (nature.com)

Norwalk virus is a small virus that consists of a single strand of RNA , which comprises the genetic material of the virus, surrounded by multiple copies of a single protein assembled into a protective coat that is called the capsid. (bcm.edu)

A study from Backer-Dirks, 18 for example, was done in 1966, prior to the widespread use of fluorides. (dentalcare.com)
The most widespread and studied type of zeolite among more than 40 types of natural and 200 types of synthetic zeolites, is natural zeolite named clinoptilolite (CZ). (nature.com)

And finally, we understand that there are herbal extracts and nutraceuticals that have been proven over centuries of use, and, at least to some degree in medical studies, to both protect liver tissue and accelerate its ability to repair itself. (jonbarron.org)

Chemicals and Drugs6

Phenomena and Processes1

Neuro-protective3

Exposure25

Mycobacterium4

Vitro2

Immunity3

Epithelial3

Oxidative stress2

Causative agent1

Chorionic gonadotropin1

Findings4

Tuberculosis3

Lung1

Demonstrate3

Substances1

Endogenous2

Cognitive decline3

Exposures1

Evaluate5

Inflammation1

Carcinogenic1

Effects19

Chemotherapy8

Pathogen4

20211

Preclinical1

Diseases4

Vaccines2

Mechanisms1

Infectious agents3

Therapeutic agents1

Preventive2

NIOSH1

Induce1

Prevention1

Investigate2

Factors8

Saliva1

Environmental2

Potentially2

Antioxidants1

Cytotoxic1

Treatments2

Viruses1

Murine2

Efficacy1

Researchers4

Methods3

Experimental2

Demonstrates1

Alcohol4

Compounds1

Rabies1

Respiratory1

Anti-inflammatory1

Cells8

Recent7

Inability1

Consumption2

Responses1

Prevalence1

Decades1

Clinical study1

Bacteria1

Systemic1

Role6

Silica1

Protein1

Widespread2

Extracts1