Study kidney damage. Medical search. Frequent questions

New York- The SARS-CoV-2 virus can directly infect a specialised type of kidney cell, explaining why acute kidney injury is one of the main complications observed in patients with severe Covid-19, finds a study. (indianewengland.com)
Over the course of the study, researchers found that those who took PPIs on a regular basis were at a much higher risk for chronic kidney disease and acute kidney injury than users of H2 blockers. (phillipslaw.com)
Layton further explained in the report, "Being dehydrated is a major factor in acute kidney injury, and then the RAS inhibitor and ibuprofen hit the kidney with this triple whammy. (eshraag.com)
The study stated that the triple medication therapy, known as "triple whammy," was associated with a 31% increased risk for acute kidney injury, compared to patients treated with diuretic and ACE inhibitor/ARB only. (eshraag.com)
The published report also stated that triple whammy acute kidney injury (AKI) occurs in 0.88%-22% of triple treatment patients. (eshraag.com)
Ferroptosis plays an important regulatory role in the occurrence and development of many diseases, such as tumors, neurological diseases, acute kidney injury, ischemia/reperfusion, etc. (nature.com)
Researchers in a 2021 study searched the international adverse effects database of the World Health Organization (WHO) for cases of acute renal failure (ARF) in people receiving treatment with remdesivir. (medicalnewstoday.com)
They noted that, compared with other antiviral medications to treat COVID-19, remdesivir was more likely to cause kidney issues, most notably acute kidney injury. (medicalnewstoday.com)
A 2022 study noted that acute kidney injury is a potential complication of COVID-19 that could be due to the use of remdesivir. (medicalnewstoday.com)
The authors highlighted the significant association between remdesivir and acute kidney injury and urged the need for more studies into its safety. (medicalnewstoday.com)
Although all of the patients in the new study had a baseline eGFR over 45, 21% of them still developed acute kidney injury (AKI) after treatment with pemetrexed. (survivingmesothelioma.com)
Review of multiple studies describes ongoing symptoms after acute COVID-19 ( 3 ). (cdc.gov)
A new study questions the decision of the FDA to place acute kidney injury warnings on Invokana and similar diabetes drugs. (aboutlawsuits.com)
Cats with renal lymphoma were excluded, as were cats with other identified causes of acute kidney injury (AKI), and cats whose creatinine increased prior to starting therapy. (vin.com)
The Swedish Society of Uroradiology has revised their computed tomography (CT) guidelines regarding iodine contrast media-induced acute kidney injury (CI-AKI). (lu.se)

The aim of this study was to examine 900-MHz mobile phone-induced oxidative stress that promotes production of reactive oxygen species (ROS) on renal tubular damage and the role of melatonin on kidney tissue against possible oxidative damage in rats. (greenmedinfo.com)
In another study, rats given vitamin U experienced less severe kidney damage after receiving valproic acid than those given no vitamin U. This substance also appeared to reduce markers of inflammation ( 6 ). (healthline.com)
In July 2023 , a study conducted by scientists from the Pharmacology and Toxicology Department at the University of Jos in Nigeria revealed significant adverse effects on kidneys and liver in rats following a 40-day administration of Fadogia extract. (kwiknews.com.my)
In a July 2023 toxicology study, the use of 50 mg/kg of Fadogia root extract resulted in significant inflammation of kidney cells in albino rats, confirming kidney damage. (kwiknews.com.my)
The study revealed significant findings regarding the effects of Fadogia extract on albino rats. (kwiknews.com.my)
Researchers in Serbia found that diabetic lab rats orally administered with the probiotic Lactobacillus paraplantarum BGCG11 experienced a reduced level of DNA damage in the liver and kidney, compared to control rats that didn't receive probiotics. (nutraingredients-usa.com)
Their aim was to assess the potential beneficial in vivo effect of the probiotic L. paraplantarum BGCG11 on diabetic complications in the liver and kidneys in diabetes-induced rats. (nutraingredients-usa.com)
"We studied the changes in redox metabolism through monitoring antioxidant enzyme activities, the level of cell injury by examining DNA damage and activation of the prosurvival Akt kinase as well as the degree of tissue damage through the activation of the fibrotic process in the liver and kidneys of diabetic rats," they wrote. (nutraingredients-usa.com)
Additionally, rats in the supplementation group exhibited decreased hyperglycemia and reduced DNA damage in the liver and kidney. (nutraingredients-usa.com)
In animal studies, problems with fertility have been seen when rats breathed very high levels of antimony for a few months. (cdc.gov)
Lung cancer has been observed in some studies of rats that breathed high levels of antimony. (cdc.gov)
But Daikin withheld a 2009 study that indicated toxicity to lab rats' livers and kidneys, while DuPont in 2012 did not alert the FDA or public to new internal data that indicated that the chemical stays in animals' bodies for much longer than initially thought. (theguardian.com)

Oxidative damage in the kidney induced by 900-MHz-emitted mobile phone: protection by melatonin. (greenmedinfo.com)
Malondialdehyde (MDA), an index of lipid peroxidation), and urine N-acetyl-beta-d-glucosaminidase (NAG), a marker of renal tubular damage were used as markers of oxidative stress-induced renal impairment. (greenmedinfo.com)
In this study, the increase in MDA levels of renal tissue and in urine NAG and also the decrease in renal SOD, CAT, GSH-Px activities demonstrated the role of oxidative mechanism induced by 900-MHz mobile phone exposure, and melatonin, via its free radical scavenging and antioxidant properties, ameliorated oxidative tissue injury in rat kidney. (greenmedinfo.com)
They also kick off a damaging process called 'oxidative stress', which compounds the problem. (kidneyresearchuk.org)
1 This means NAC can fight off excessive oxidative stress, a process that's damaging to the body when it occurs at high levels. (traceminerals.com)
FABP1 binds long-chain fatty acids, contributing to reducing oxidative stress in the kidneys. (randox.com)

A recent study has linked proton pump inhibitor (PPIs), medications used to suppress heartburn and acid reflux disease, to increased risk of kidney damage. (phillipslaw.com)
Other medications may be effective and pose a lower risk of kidney damage. (medicalnewstoday.com)
In a 2020 study , researchers found that remdesivir had little or no effect on the risk of kidney damage. (medicalnewstoday.com)
At least 75% of Americans are at risk of kidney damage from dehydration. (alkalinewaterplus.com)
The authors conclude that the above factors increase the risk of kidney damage in cats undergoing doxorubicin therapy. (vin.com)

This study was conducted as part of a toxicology and safety assessment published in Scientific African in July 2023. (kwiknews.com.my)
Retrieved on Dec 04, 2023 from https://www.medindia.net/news/healthwatch/eat-healthy-to-keep-kidney-disease-at-bay-190529-1.htm. (medindia.net)

June 27, 2020 Progression of kidney disease in type 1 diabetes is correlated with increased amounts of uric acid. (sciencedaily.com)
Health experts are concerned that many of those prescribed PPIs to treat heartburn and acid reflux disease may have developed kidney problems without displaying any warning signs. (phillipslaw.com)
The gut microbiome is altered in chronic kidney disease (CKD), potentially contributing to CKD progression and co- morbidities , but population -based studies of the gut microbiome across a wide range of kidney function and damage are lacking. (bvsalud.org)
A study published in the International Journal of Environmental Research and Public Health found that malathion , the most popular organophosphate insecticide in the U.S., significantly increases the risk of developing chronic kidney disease (CKD) . (naturalnews.com)
Data from the Centers for Disease Control and Prevention (CDC) shows that at least 37 million (15 percent) of adults in America have chronic kidney disease (CKD). (naturalnews.com)
Even if someone has severe kidney disease, only three out of five individuals with the condition know that they are sick. (naturalnews.com)
Chronic kidney disease , or chronic kidney failure, causes damage to your kidneys and results in loss of kidney function. (naturalnews.com)
In time, kidney disease can get worse and cause kidney failure. (naturalnews.com)
This damage can cause wastes to build up in the body, leading to health issues like heart disease, high levels of potassium in the blood, pulmonary edema, seizures and irreversible kidney damage. (naturalnews.com)
Unfortunately, the early stages of kidney disease are often symptomless and some cases often go unnoticed until it is too late. (naturalnews.com)
More advanced kidney disease may cause symptoms such as chest pain, confusion, fatigue, loss of appetite, nausea, shortness of breath, urination that becomes less or more frequent and vomiting. (naturalnews.com)
The researchers also wanted to learn more about the growing incidence of unexplained chronic kidney disease in tropical countries. (naturalnews.com)
Every piece of research brings us one step closer to transforming treatments and freeing lives from kidney disease. (kidneyresearchuk.org)
Professor Will Herrington , pictured right, and his colleagues at the University of Oxford, used genetics to show obesity can increase the chances of someone developing kidney disease. (kidneyresearchuk.org)
High blood pressure is a major cause of kidney disease. (kidneyresearchuk.org)
An early sign of kidney disease is detecting protein in the urine. (kidneyresearchuk.org)
The researchers would now like to investigate whether blocking Neuropeptide Y could prevent the loss of protein, and even interrupt the early stages of kidney disease. (kidneyresearchuk.org)
Approximately 35 percent of older cats suffer from chronic kidney disease, but the reason was not known, she said. (petfoodindustry.com)
Earlier research found evidence that high phosphorus concentrations in cat food could make kidney disease worse in cats that were already ill. (petfoodindustry.com)
Now, her team has evidence that unnecessary, excessive phosphorus levels in cat food may harm the kidneys of healthy, younger cats, potentially leading to later kidney disease. (petfoodindustry.com)
Those synthetic forms of phosphorus may be the culprits in cat kidney disease. (petfoodindustry.com)
Farmers in the Balkans are failing to weed out the cause of a kidney disease, according to a new study that appears to have resolved a decades-long mystery. (newscientist.com)
Arthur Grollman, at the University at Stony Brook, New York, US, did not expect to discover birthwort as the cause of this kidney disease when he set out for the region a few years ago. (newscientist.com)
Spontaneously hypertensive rat (SHR) is a laboratory rat which is an animal model of primary hypertension, used to study cardiovascular disease. (wikipedia.org)
A 2020 study of over 1,000 people hospitalized with the disease found that it safely and effectively shortened the time to recovery in adults. (medicalnewstoday.com)
A new study indicates that thousands of individuals have had kidneys removed unnecessarily because doctors misdiagnosed their disease. (science20.com)
So, disease prevention is key to keeping the kidneys healthy. (alkalinewaterplus.com)
Eating a healthy diet may protect you from chronic kidney disease (CKD), according to an analysis of published studies. (medindia.net)
Making dietary changes can help slow the progression of chronic kidney disease (CKD), but it's not clear whether a healthy diet is protective against the development of the disease. (medindia.net)
Adhering to a diet based on nutrient-rich plants could lower a person's risk of developing chronic kidney disease (CKD) and slow the decline of kidney function. (medindia.net)
So, make sure to add plenty of vegetables, fruit, legumes, whole grains, nuts, fish, and low-fat dairy products and avoid red and processed meats, salty foods and sugary drinks to keep chronic kidney disease (CKD) at bay. (medindia.net)
Chronic renal failure or chronic kidney disease is progressive loss in kidney function. (medindia.net)
For example, urologists can keep an eye on kidney disease, you can also think about gastrointestinal specialists that should be aware of the fact that maybe the high consumption of micro- and nanoplastics can trigger inflammatory bowel disease, et cetera. (medpagetoday.com)
Now a new study from Boston University finds a clear connection between the disease and the work these men are doing. (kpcw.org)
The decline in kidney function during the harvest and the differences [in kidney function] by job category and employment duration provide evidence that one or more risk factors of CKD (chronic kidney disease) are occupational," the report says. (kpcw.org)
He died of kidney disease two months later. (kpcw.org)
She hopes this study will help researchers better understand the disease and find a way to prevent it. (kpcw.org)
Plasma galectin-3 (Gal-3) is associated with organ fibrosis, but whether urinary Gal-3 is a potential biomarker of kidney disease progression has never been explored. (mdpi.com)
Chronic kidney disease affects more than 697 million people around the world. (ibecbarcelona.eu)
In almost all cases of chronic kidney disease, damage occurs in these cells, but until now, it was not known which cellular mechanisms were respon sible for such dysfunction. (ibecbarcelona.eu)
Specifically, in the kid neys of mice with chronic kidney disease, they detected that a greater proportion of the proximal tubule cells had a different molecular signature than that found in the kidneys of healthy animals. (ibecbarcelona.eu)
The man's calcium and vitamin D levels returned to normal after about a year, although he continues to live with stage 3 chronic kidney disease. (ctvnews.ca)
Several kidney biomarkers are used successfully in drug development, however cost-efficient, and reliable kidney biomarkers are urgently needed for monitoring farm animals for early signs of kidney disease. (frontiersin.org)
The purchase of this research is to determine the mechanisms and factors that establish and maintain tubular diameter, to understand the pathobiology of polycystic kidney disease (PKD) and to use this information to find a therapy for PKD. (nih.gov)
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by mutations in PKD1 (approximately 85 percent) or PKD2 (approximately 15 percent) and is the most common genetic cause of PKD. (nih.gov)
In polycystic kidney disease (PKD), these tubes start to dilate and can become large balloons (cysts) filled with fluid. (nih.gov)
Chronic kidney disease (CKD) mainly comprises persistent reduction of kidney's blood-filtering ability, expressed as glomerular filtration rate (GFR) below 60 ml/min/1.73 m 2 for more than 3 months. (uclahealth.org)
How are Chronic kidney disease and Cardiovascular disease related? (uclahealth.org)
Kidney disease often goes undetected until it's too late, and kidney damage in children can result in a lifetime of hospital visits. (lupus.org)
Dr. Eyal Muscal of Texas Children's Hospital studied how to better define what changes in white-matter are causing disease. (lupus.org)
Chronic Kidney Disease is an abnormal kidney function and/ or structure, present for a minimum period of 3 months. (randox.com)
Utilising patented Biochip Technology, the Randox Chronic Kidney Disease (CKD) arrays could improve patient risk stratification whilst monitoring the effectiveness of treatment. (randox.com)
Diagnosis of CKD at early stages will allow earlier intervention for the treatment of kidney disease, and the prevention of further kidney damage. (randox.com)
[ 140 ] In a retrospective study of 16,186 patients with initial serum uric acid levels above 7 mg/dL, Levy and colleagues found that patients with gout who remained on urate-lowering therapy were less likely to develop kidney damage leading to chronic kidney disease than those who were untreated. (medscape.com)
Science from industry, the FDA and independent researchers now links 6:2 FTOH to kidney disease, liver damage, cancer, neurological damage, developmental problems and autoimmune disorders, while researchers also found higher mortality rates among young animals and mothers exposed to the chemicals. (theguardian.com)
One of the major adverse effects of doxorubicin in cats is cumulative renal damage- ie, the propensity for cats to develop kidney disease with large total doses of medication. (vin.com)
Chronic kidney disease (CKD) was diagnosed in 41% of cats prior to the initiation of therapy with doxorubicin. (vin.com)
This study aimed to evaluate the hematological and coagulation parameters according to the clinical outcomes of coronavirus disease (COVID-19). (bvsalud.org)
Our study shows that significant alterations in hematological and coagulation tests at admission could be useful predictors of disease severity and mortality in COVID-19. (bvsalud.org)
In June 2016, I was at that meeting in New Orleans, and I was drawn to a session about the epidemiology of diabetic kidney disease (DKD). (medscape.com)
In this case, I was fortunate to have an existing contract with a pharmaceutical company to study the progression of eGFR-defined chronic kidney disease (CKD) in people with and without diabetes. (medscape.com)
We would use the test results to classify patients into six eGFR categories and three albuminuria categories specified in Kidney Disease: Improving Global Outcomes (KDIGO). (medscape.com)

For this, the analyzes were carried out with animal models and human mini-kidneys. (ibecbarcelona.eu)
Noting these observations, the IBEC researchers went one s tep further and, using human mini-kidneys, demonstrated that these changes were due to a decrease in the expression of some of the genes that regulate lipid metabolism in proximal tubule cells. (ibecbarcelona.eu)
Furthermore, "thanks to a multidisciplinary approach, using an imal models and human mini-kidneys that we generate through bioengineering at IBEC, we discovered that, by correcting this deficiency, the proximal tubule cells could regain their function in the different study models," explains Dr. Montserrat. (ibecbarcelona.eu)
Combining single cell RNA-sequencing, and the use of bioengineering to produce mini-kidneys, they were able to identify the key cellular level differences between healthy and diseased kidneys. (ibecbarcelona.eu)
H uman mini-kidneys -also called kidney organoids- are created using bioengineering techniques from human stem cells, and capture some aspects of the complexity of this organ. (ibecbarcelona.eu)
Last April, the researchers demonstrated their effectiveness as a study model by u sing them to decipher in record time how SARS-CoV-2 interacts and infects the cells of these mini-kidneys, in addition to identifying a therapy aimed at reducing viral load. (ibecbarcelona.eu)

Kidney trait-related microbiome features were interrogated for correlation with serum metabolites (n = 700), and associations of microbiome -related serum metabolites with kidney trait progression were examined in a prospective analysis (n = 3,635). (bvsalud.org)

Recent studies have shown that ferroptosis is closely related to the pathophysiological processes of many diseases, such as tumors, nervous system diseases, ischemia-reperfusion injury, kidney injury, and blood diseases. (nature.com)
20% of individuals with kidney tumors common in patients with tuberous sclerosis complex (TSC), a genetic disorder, has had a kidney removed. (science20.com)
The Food and Drug Administration in April approved everolimus to treat noncancerous kidney tumors (renal angiomyolipomas) not requiring immediate surgery in patients with TSC, based on the research led by the Cincinnati Children's team. (science20.com)
TSC can cause multiple tumors in both kidneys that compress normal tissue as they grow, leading to kidney failure and bleeding due to uncontrolled blood vessel growth. (science20.com)
I can't tell you how many times I've heard from patients who say their doctors told them a kidney looks bad, is full of tumors, isn't working and has to come out," says Bissler, who co-directs the Tuberous Sclerosis Clinic at Cincinnati Children's. (science20.com)
Doctors are unfamiliar with tuberous sclerosis, so when they see tumors, they think it's renal cell carcinoma, perform surgeries trying to help, but before long the kidney is gone. (science20.com)
In most cases, there will be a solitary tumor in one kidney, but 5-13% of children have bilateral tumors and 10% have multifocal tumors in a single kidney. (medscape.com)

The investigators also found that they could reduce the effects of uric acid accumulation and improve fruit fly survival by inhibiting free radicals -- unstable atoms that cause damage to cells -- using antioxidants like Vitamin C or by suppressing a gene called NOX. (sciencedaily.com)
Antioxidants: Ionized alkaline water fights free radicals to help kidney health. (alkalinewaterplus.com)
Selenium is one of several nutrients known to have antioxidant properties, meaning selenium plays a part in chemical reactions that stop free radicals from damaging cells and DNA. (livescience.com)

Consuming too much alcohol, red meat and sugary beverages all contribute to high levels of uric acid in the blood or urine, which increases the risk of gout, kidney stones, metabolic syndrome, obesity, diabetes and early death. (sciencedaily.com)
Your kidneys filter extra water and wastes out of the blood to make urine and ensure that your body works properly by balancing the salts and minerals, such as calcium, phosphorus , potassium and sodium, that circulate in the blood. (naturalnews.com)
Healthy kidneys filter out waste products in our blood to make urine, while stopping essential proteins from escaping. (kidneyresearchuk.org)
Can urine-based markers in children with IgA vasculitis help us to understand, predict and prevent kidney damage? (kidneyresearchuk.org)
An important component of the kidney are the tubes that make urine. (nih.gov)
Sometimes they are disconnected from the other tubes, are no longer capable of making urine and compress and damage nearby tubes. (nih.gov)
It is also diagnosed if certain markers of kidney damage are identified in blood or urine tests, or imaging studies. (uclahealth.org)
Not all patients had a UACR, and some clinicians apparently assessed kidney damage with a urine protein dipstick rather than the UACR. (medscape.com)

Using innovative techniques such as single cell RNA-sequencing, the researchers unraveled the crucial role tha t lipid metabolism genes play in protecting against chronic kidney failure. (ibecbarcelona.eu)

A recent study by scientists from the University of Jos, Nigeria, revealed severe inflammation of the kidneys and liver tissue necrosis at varying doses based on body weight (50 mg/kg, 100 mg/kg, and 200 mg/kg) after 40 days. (kwiknews.com.my)
Similarly, at a higher dose of 100 mg/kg, the study also revealed substantial inflammation of red blood cells within the tissue and a reduction in interstitial spaces caused by Fadogia Agrestis. (kwiknews.com.my)
TSPO PET brain inflammation imaging: A transdiagnostic systematic review and meta-analysis of 156 case-control studies. (iasp-pain.org)
In other words, the beneficial bacteria "overwhelm intestinal inflammation," reducing the activity of common toxins that damage the liver and kidneys among diabetic populations. (nutraingredients-usa.com)
inflammation, cell necrosis, and dysfunction in the kidney. (theecologist.org)
Another study of 207 COVID-19 patients similarly found defective immune recovery drive ongoing diseases .A pronounced early immune response and no evidence of systemic inflammation is seen in patients with mild diseases, meanwhile. (theepochtimes.com)
The persistent elevation of inflammation-causing immune cells could be causing some of the common long COVID symptoms: neuroinflammation, injury to the kidneys, insulin resistance, and others. (theepochtimes.com)

Primarily known to infect cells in the respiratory tract, physicians were surprised to see that many patients, especially those with severe Covid, were also developing injuries to their kidneys. (indianewengland.com)
It was shocking to hear doctors describe how patients who were healthy suddenly developed kidney injury and needed to go on dialysis after contracting SARS-CoV-2," said Samira Musah, assistant professor of biomedical engineering and medicine at Duke University. (indianewengland.com)
The five-year study, published in Kidney International, looked at 125,596 patients prescribed over-the-counter PPI medications, such as Prevacid, Nexium and Prilosec, as well as those who used H2 blockers like Zantac or Pepcid. (phillipslaw.com)
The clinical trials we fund can improve the care kidney patients receive today. (kidneyresearchuk.org)
Unlike most patients with kidney failure, people with the Balkan illness often have healthy blood pressure. (newscientist.com)
Back in the lab, Grollman and his colleagues examined kidney samples from Croatian nephropathy patients. (newscientist.com)
The investigators found that in some patients with certain medical profiles, the combination of the three medications could cause kidney damage, which in some cases can be permanent, according to a news release. (eshraag.com)
Additionally, increased drug sensitivity or low water intake can predispose patients to triple whammy AKI," the investigators wrote in their study. (eshraag.com)
The new Cincinnati Children's study shows that everolimus, marketed by Novartis under the tradename Afinitor®, successfully shrinks AMLs in patients with TS. (science20.com)
The Cincinnati Children's study involved 118 TSC patients at 24 treatment centers in 11 countries. (science20.com)
But you can do studies on these patients and find out that they have normal kidney function. (science20.com)
In one study, patients who took 1,200 mg/day of NAC in combination with weekly intravenous NAC, had better neurological health and improvement in midbrain dopamine neurons. (traceminerals.com)
Dr. Kelly noted that dietary approaches to kidney health that target individual (or multiple) nutrients can be difficult, but focusing on whole foods rather than nutrients can make it easier for clinicians to educate patients and easier for patients to carry out. (medindia.net)
These include, for example, [microplastics in] the placenta , meconium -- the first stool of a newborn -- it has been detected in the lung tissue of living patients, in colon tissue biopsies, and then in our study, also in whole blood of healthy donors. (medpagetoday.com)
Italian scientists studying the popular mesothelioma chemotherapy drug pemetrexed (Alimta) have some sobering news for patients: Kidney damage remains a risk, even in patients whose kidney function tests are on the low end of normal. (survivingmesothelioma.com)
Doctors in the nephrology and dialysis unit at St. Andrea Hospital in La Spezia, Italy, performed a retrospective evaluation of 38 patients with non-small cell lung cancer who developed kidney injuries after being treated with pemetrexed. (survivingmesothelioma.com)
The guidelines for administering pemetrexed to patients with mesothelioma, NSCLC, and other types of cancer say that the patient's eGFR, a measure of kidney function, should be higher than 45. (survivingmesothelioma.com)
The new study suggests that, for mesothelioma patients and others on this treatment, risk factors for AKI should be corrected, if possible, even in cases where the baseline eGFR level meets the recommended guidelines. (survivingmesothelioma.com)
In the current prospective study, 20 malignant pleural mesothelioma patients underwent radical pleurectomy/decortication followed by high doses of radiation. (survivingmesothelioma.com)
Most of the information on health effects of dinitrophenols comes from old studies of patients who were prescribed diet pills containing dinitrophenol before it was banned. (cdc.gov)
The identification of this mechanism, alongside the current development of specific AXL inhibitors, provides the rationale for further studies that may improve treatment for EGFR inhibitor-resistant patients. (nature.com)
As a general rule, asymptomatic hyperuricemia should not be treated, though ultrasonographic studies have demonstrated that urate crystal deposition into soft tissues occurs in a minority of patients with asymptomatic hyperuricemia. (medscape.com)
[ 140 ] The hazard ratio for kidney damage was 1.08 (95% confidence interval, 0.76-1.52) in patients who received urate-lowering therapy more than 80% of the time and was 1.27 (95% confidence interval, 1.05-1.55) in those who received urate-lowering therapy less than 80% of the time. (medscape.com)
In a study of gout flares in patients newly started on urate-lowering therapy, Rashid et al found that 68% of these patients had one or more gout flares during the first 12 months of therapy. (medscape.com)
In a study of ultrasound and laboratory findings in Wilms tumor survivors with a solitary kidney, signs of kidney damage were seen in 22 of 53 patients (41.5%) on ultrasonography. (medscape.com)
They are more cautious compared to the European Society of Urogenital Radiology and the American College of Radiology since the actual risk of CI-AKI remains uncertain in patients with moderate to severe kidney damage due to a lack of prospective controlled studies and mainly based on retrospective propensity score-matched studies with low-grade evidence. (lu.se)
We studied 128 patients with COVID-19 (59.2±17.7 years, 56% male). (bvsalud.org)

Those researchers found evidence that when phosphate concentrations in cat food exceed the required daily dose, it may damage healthy cats' kidneys. (petfoodindustry.com)
Although previously regarded as harmless, Kienzle's team found that the maximum level detected in these tests (nearly nine times the required amount) might be sufficient to damage healthy feline kidneys within a few weeks. (petfoodindustry.com)
He knew about the disastrous mix-up in which thousands of healthy Belgium women developed severe kidney failure requiring transplants after accidentally receiving the Chinese herbal drug guang fang ji instead of the similar-sounding han fang ji. (newscientist.com)
Embolization, however, can also damage healthy tissue. (science20.com)
Healthy kidneys help to balance our body's pH, electrolyte levels, red blood cell-count, and blood pressure. (alkalinewaterplus.com)
Eating a healthy diet can cut down the risk of albuminuria, an early indicator of kidney damage. (medindia.net)
In healthy adults, each of o ur kidneys contains an average of 1.5 million nephrons, the basic functional units of the kidney that constantly filter waste products from the blood. (ibecbarcelona.eu)
By sequencing the RNA of each of the thousands of cells present in the kidney, the researchers observed for the first time important differences between healthy and diseased cells in the proximal tubule. (ibecbarcelona.eu)
Some evidence for this theory comes from one small study of 31 individuals with long COVID, matched with 31 others who had COVID, but who recovered normally (and also 46 healthy controls). (theepochtimes.com)

A new fruit fly model that mimics diseases associated with high uric acid levels, such as gout and kidney stones, has revealed new targets for developing treatments for these diseases. (sciencedaily.com)
It has long been suspected that fluoride may contribute to the formation of kidney stones. (fluoridealert.org)
In traditional medicine chaparral tea is used to treat gallbladder and kidney stones. (cancerresearchuk.org)
The man said his naturopath had never warned him about vitamin D toxicity, which can cause hypercalcemia, which in turn can weaken bones and cause kidney stones, among other common symptoms. (ctvnews.ca)

However, people with kidney impairment or failure may experience liver or kidney toxicity due to the release of this substance. (medicalnewstoday.com)
A new study, to be published in the journal Environmental Research, adds further support to recent conclusions on fluoride toxicity by the National Academy of Sciences (NAS). (fluoridealert.org)
The legal limit for monochlorobenzene, established in 1991, was based on a toxicity study in laboratory animals conducted in the 1960s. (ewg.org)
And though Daikin may have broken the law, it and DuPont, which has previously been caught hiding studies that suggest toxicity in PFAS, are not facing any repercussions. (theguardian.com)

Pankaj Kapahi of Buck Institute and colleagues report these findings in a new study published 15th August in PLOS Genetics . (sciencedaily.com)
Meanwhile, findings from human studies have linked malathion to kidney damage. (naturalnews.com)
9/5/2013 - It has been almost a year now since French researcher and scientist Gilles-Eric Seralini published his groundbreaking study on the deleterious effects of eating Monsanto's genetically-modified (GM) corn, and there are still millions of people out there who are confused about its controversial findings. (naturalnews.com)
A new study raises questions about FDA findings that Invokana and similar diabetes drugs can increase the risk of bone fractures. (aboutlawsuits.com)

Twenty nine of the study participants had no other risks for renal damage. (survivingmesothelioma.com)

Weight gain or obesity endangers the kidneys as well. (alkalinewaterplus.com)

Compared to the other group, cats that ate the high phosphorus diet showed signs of glucosuria and albuminuria, which indicated kidney damage. (petfoodindustry.com)
Although previous studies had combined proteinuria and albuminuria data, we chose to keep our KDIGO albuminuria categories "pure. (medscape.com)

Kidney proximal tubules were isolated from control and phenobarbital induced rabbits by nonenzymatic sieving techniques and then studied in-vitro. (cdc.gov)
Proximal tubules obtained in bulk by nonenzymatic procedures were resistant to cell damage by levels of chloroform (67663) and carbon-tetrachloride (56235) likely to be encountered in the work place. (cdc.gov)
These kidney organoids contain renal structures including proximal tubules (marked with LTL, in green) and podocytes (expressing PODXL, in red) t hat partly resemble the renal structures of the human kidney. (ibecbarcelona.eu)

The change is irreversible and is due to loss of nephrons of the kidney. (medindia.net)

A new study warns that Farxiga fares little better than a placebo at preventing heart attacks and strokes, but increases the risk of genital infections and diabetic ketoacidosis. (aboutlawsuits.com)

Recent studies have shown that ferroptosis plays an important regulatory role in the occurrence and development of many diseases and has become the focus and hotspot of research on the treatment and prognosis improvement of related diseases (Fig. 1 ). (nature.com)

The contamination of the region's wheat by the birthwort plant seems to be the source of an unusual form of kidney failure and urinary tract cancer that afflicts many people in countries such as Croatia and Serbia. (newscientist.com)
A new study finds that strenuous labor in the sugar cane fields of Central America is contributing to a mysterious form of kidney failure. (kpcw.org)
Over the past two decades, more than 20,000 people in western Nicaragua and El Salvador - mostly men and many of them in their 20s and 30s - have died of a mysterious form of kidney failure. (kpcw.org)

The World Health Organization (WHO) has categorized malathion as a "probable carcinogen," and data from animal studies has linked the pesticide to birth defects and certain kinds of cancer. (naturalnews.com)
Nonetheless, as their kidneys begin to fail they require dialysis and about half of them eventually develop a rare cancer of the upper urinary tract. (newscientist.com)
Researchers have tested M4N in laboratory studies on mouse and human cancer cells. (cancerresearchuk.org)
The study looked at 45 people with advanced cancer. (cancerresearchuk.org)
Some laboratory studies show that NDGA might have anti cancer properties. (cancerresearchuk.org)
Early studies with M4N have shown that M4N stops the growth of several types of mouse and human cancer cells. (cancerresearchuk.org)

The demand for kidney transplants outweighs the supply of donated organs. (kidneyresearchuk.org)
Kidneys are one of the main organs God gave us to detox our bodies. (alkalinewaterplus.com)
Two new studies report mutations in FAN1 and three other genome-stability genes that tie the DNA damage response to progressive kidney failure and the dysfunction of several other organs. (nature.com)

May 17, 2021 Researchers have found out how microscopic structures called lipid droplets may help to prevent a high-fat diet causing kidney damage. (sciencedaily.com)
2021) Low Dose Power Angiotensin II Induces Selective Senescence of Kidney Endothelial Cells. (visualassembler.com)
Another 2021 study noted that doctors have successfully and safely treated several other viral infections with remdesivir. (medicalnewstoday.com)
Another 2021 study found similar results. (medicalnewstoday.com)

We found that the virus was especially adept at binding to two key receptors on the surface of the podocytes, and these receptors are abundant in these kidney cells," explained Titilola Kalejaiye, a postdoctoral fellow at Duke. (indianewengland.com)
The virus seemed to have a strong affinity for these kidney cells. (indianewengland.com)
Once the virus infected the cells, it damaged the podocytes, causing their long, finger-like structures, which help filter blood, to retract and shrivel. (indianewengland.com)
Beyond the structural damage, we saw that the virus could hijack the machinery of the podocytes to produce additional viral particles that could spread to infect additional cells," said Maria Blasi, Assistant Professor of medicine at Duke. (indianewengland.com)
Now the team hopes to expand their work to study how the different variants of SARS-CoV-2 behave in kidney cells. (indianewengland.com)
Additionally, the kidneys produce hormones that help control blood pressure, make red blood cells and promote bone strength. (naturalnews.com)
Dr Emily Thompson and colleagues at Newcastle University pumped blood and stem cells through kidneys in the lab. (kidneyresearchuk.org)
Thus, we examined the effect of sodium fluoride on intracellular calcium mobilization in a normal rat kidney epithelial cell line (NRK-52E cells). (fluoridealert.org)
Tubule cells propagated in-vitro were more susceptible to cell damage caused by these organic solvent s. (cdc.gov)
That means it protects cells from damage. (cancerresearchuk.org)
Confocal microscopy image of a kidney organoid generated in vitro from human pluripotent stem cells that have been differentiated for 20 days using three-dimensional cultures. (ibecbarcelona.eu)
In a CKD patient with anemia, damaged kidneys are not able to produce adequate amounts of a hormone called erythropoietin, which stimulates bone marrow to produce red blood cells. (uclahealth.org)
This study improved our understanding of how puberty affects the functional state of these white blood cells, and the pathways whose function is altered as a child progresses through the orderly series or hormone production in puberty. (lupus.org)

Finally, we have identified a fragment of PC1 that can alter mitochondrial function and morphology, but further studies are required to determine how and if/how this mitochondrial dysfunction results in cyst formation. (nih.gov)
Cystatin C is well recognised marker of kidney filtration dysfunction and injury. (randox.com)

13 However, in one other study, very high oral NAC doses (6,000mg/day) resulted in a worsening of symptoms, indicating more studies are needed to find out if NAC can be beneficial for neurological health. (traceminerals.com)
A recent study identified a cell free RNA (cfRNA) signature that was promising in predicting pre-eclampsia several weeks before the onset of symptoms. (cdc.gov)

Data from animal studies have previously revealed that exposure to malathion increases markers of kidney injury, like levels of serum creatinine and urea. (naturalnews.com)
Also, creatinine clearance, a measure of the overall kidney performance, dropped markedly within 28 days in cats eating a diet rich in phosphorus. (petfoodindustry.com)
According to the case study, the man's doctor sent him to a kidney specialist after discovering that the 54-year-old was producing nearly four times the normal level of creatinine, a waste product often measured to determine whether kidneys are functioning properly. (ctvnews.ca)
Cats were included in the study if they received doxorubicin therapy and had a creatinine measured before and after therapy. (vin.com)

The tissue cell damage caused by Fadogia remains a significant concern among herbal enthusiasts. (kwiknews.com.my)
Few studies have investigated the degree of tissue destruction associated with white phosphorus injuries. (medscape.com)

Malathion undeniably "increases the risk of low kidney function in the general US population," concluded Osborne. (naturalnews.com)
Transplanting a kidney from SHR to a normotensive Wistar rat increases blood pressure in the recipient. (wikipedia.org)

"Randomized clinical trials with sufficient follow-up time to ascertain meaningful kidney outcomes are necessary to determine whether a change in dietary patterns is causally related to favorable kidney health outcomes," wrote the authors of an accompanying editorial. (medindia.net)

If your kidneys fail, you will need dialysis throughout your whole life or a kidney transplant to maintain your health. (naturalnews.com)

Additionally, research suggests a link between remdesivir and kidney failure that may lead to severe lung issues. (medicalnewstoday.com)
In long-term studies, animals that breathed very low levels of antimony had eye irritation, hair loss, lung damage, and heart problems. (cdc.gov)

Association of the gut microbiome with kidney function and damage in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). (bvsalud.org)
Kidney function is a significant correlate of the gut microbiome , while the relationship of kidney damage with the gut microbiome depends on diabetes status. (bvsalud.org)
Study co-author Nicholas Osborne, an associate professor at the Queensland University School of Public Health , reported that there was evidence of altered kidney function in individuals people exposed to malathion. (naturalnews.com)
The contrast can worsen kidney function problems in people with poorly functioning kidneys. (medlineplus.gov)
In addition, numerous studies have been conducted in the SHR in relation to other elements of ADHD, for example, looking at the impact of different drug treatments such as atomoxetine and methylphenidate on tests of impulsivity and attention and hyperactivity, investigating possible neural correlates of heightened distractibility in ADHD and assessing reward function. (wikipedia.org)
Therefore, health experts recommend testing a person's kidney function before they start the medication. (medicalnewstoday.com)
A person with reduced kidney function should discuss this with a doctor. (medicalnewstoday.com)
The researchers found that the kidney function of field workers declined over the course of the six-month harvest. (kpcw.org)
It found that field workers whose primary jobs were spraying for weeds and pests (and who thus had the most contact with agricultural chemicals) had the least decline in kidney function over the course of the harvest. (kpcw.org)
Cutters who drank more of a generic energy drink while on the job had less of a drop in kidney function than co-workers who drank less of the beverage. (kpcw.org)
The sugar plantation tests workers' kidney function at the beginning of each year's harvest. (kpcw.org)

CKD can also progress to end-stage kidney failure, which is fatal unless you undergo dialysis or a kidney transplant. (naturalnews.com)

Kidney damage is not the only serious health hazard that can result from long-term PPI use. (phillipslaw.com)
Several international studies have linked long-term PPI use to serious health problems. (phillipslaw.com)
For the study, researchers looked at the effects of pesticides on kidney health in the U.S. population. (naturalnews.com)
Kienzle, along with Britta Dobenecker, DVM, led the research on phosphorus' effects on cat kidney health. (petfoodindustry.com)
Ongoing research by Kienzle's team is looking at how phosphorus source influences kidney health in cats and dogs. (petfoodindustry.com)
While scientists continue to research how phosphorus sources affect cats and dogs kidney health, pet food formulators may wish to reconsider the type and quantities of phosphorus-containing ingredients used in cat and dog food. (petfoodindustry.com)
It may affect kidney health. (medicalnewstoday.com)
However, several other studies point to remdesivir having potentially adverse effects on kidney health. (medicalnewstoday.com)
Studies show three ways ionized alkaline water help with kidney health. (alkalinewaterplus.com)
Studies show validity of these health claims. (alkalinewaterplus.com)
In some studies, NAC supports the kidney health of people given a contrast agent. (traceminerals.com)
If you look at occupational studies, animal experiments, and also recent work done with human cell models, human organoids, et cetera, then I think there are strong indications for health effects and there's a whole range of health effects we can mention here. (medpagetoday.com)
The case study notes that there are also claims it can increase cardiovascular health and reduce infection risk, although there is little scientific basis for these assertions. (ctvnews.ca)
But documents show that the FDA first became aware of DuPont's hidden study in 2015, and public health advocates say a 10-year timeline to reassess and remove the chemical is unacceptable. (theguardian.com)
In a statement to the Guardian, an FDA spokesperson defended the agency's handling of 6:2 FTOH, noting that the studies "do not demonstrate an imminent health hazard" and more studies were needed to draw concrete conclusions about its safety, and that of other short chain PFAS. (theguardian.com)
Through our Health Links - program and the CDC-funded Small + Safe + Well Study, business leaders learn how to improve and measure employee well-being and become champions for a healthier, safer culture. (cdc.gov)

The researchers found that these results are notably pronounced within the kidneys and never within the mind or lungs, which is what they anticipated once they began their experiments. (visualassembler.com)
12 In another study, researchers found that high oral doses of NAC safely raised levels of NAC in the cerebrospinal fluid without any adverseeffects. (traceminerals.com)

The US Food and Drug Administration denied its oversight had been lax but said more studies were needed to draw conclusions about the safety of short chain PFAS. (theguardian.com)

Other antiviral medications may help treat COVID-19 and be safer for the kidneys. (medicalnewstoday.com)

For example, kidneys transplanted from SHR to a hypertensive recipient retain better morphology than kidneys transplanted from Brown Norway, demonstrating a pathological adaptation to high blood pressure. (wikipedia.org)

As the major part of the lactic acid bacteria group, [Lactobacillus] can delay diabetes onset due to their antidiabetic potential," they wrote, citing a 2015 study published in the Journal of Functional Foods. (nutraingredients-usa.com)
Researchers have been able to say definitively that it's not diabetes or other common causes of kidney failure. (kpcw.org)
A new study by FDA researchers appears to verify links between Invokana and similar diabetes drugs and a life-threatening infection that attacks the genitals. (aboutlawsuits.com)

In another laboratory study in 2017 researchers developed a chemical from NDGA. (cancerresearchuk.org)

For the new study, described in the journal Frontiers in Cell and Developmental Biology, the team worked worked with a pseudovirus version of SARS-CoV-2 on a previously developed model of podocyte cell, a specific type of kidney cell that helps control the removal of toxins and waste from the blood. (indianewengland.com)
When the kidneys are working correctly they remove toxins of all kinds and wastes from the blood all day long. (alkalinewaterplus.com)
Drinking ionized water helps to eliminate toxins, toxic metals, and excess mineral buildup in the kidneys. (alkalinewaterplus.com)

At 29 weeks pregnant, Erica was diagnosed with preeclampsia, a pregnancy complication marked by high blood pressure and signs of organ failure, most often liver or kidney damage. (cdc.gov)

In high doses NDGA causes liver damage. (cancerresearchuk.org)
However, not all cats seem equally susceptible, and kidney damage may occur at different total doses in different animals. (vin.com)
Several studies have demonstrated that daily doses up to 1,000 micrograms of chromium are safe. (msdmanuals.com)

A study was conducted to examine the validity of the isolated rabbit tubule model as a tool in the study of nephrotoxicants and to determine the validity of the rabbit tubule model as a predictor of nephrotoxicity in humans. (cdc.gov)
Although the kidney functions as the major excretory system in mammals, monitoring and screening for mycotoxin induced nephrotoxicity is only now a developmental area in the field of livestock feed toxicology. (frontiersin.org)

Other experts added that the powdered form may be safe for people with kidney issues. (medicalnewstoday.com)
Can people with kidney issues take remdesivir? (medicalnewstoday.com)
People with kidney issues should avoid using remdesivir. (medicalnewstoday.com)
Chromium supplements should not be used by people with kidney or liver disorders or by people with iron deficiency. (msdmanuals.com)

There's a urgent want to deal with the intense systemic results of hypertension and give you novel remedies to keep away from or reverse harm to the kidneys," says Anton Wellstein, MD, PhD, professor of oncology and pharmacology at Georgetown Lombardi and corresponding writer for this text. (visualassembler.com)

Anatomy30

Organisms15

Diseases44

Chemicals and Drugs62

Analytical, Diagnostic and Therapeutic Techniques and Equipment52

Phenomena and Processes54

Disciplines and Occupations2

Information Science4

Named Groups2

Health Care15

Acute15

Rats12

Oxidative6

Risk of kidney damage5

20232

Disease62

Mini kidneys6

Progression1

Tumors7

Free radicals3

Urine8

Chronic kidney1

Inflammation7

Patients27

Healthy9

Stones4

Toxicity4

Findings4

Renal damage1

Obesity1

Albuminuria2

Proximal tubules3

Irreversible1

Diabetic1

Diseases1

Form of kidney failure3

Cancer6

Organs3

20214

Cells13

Dysfunction2

Symptoms2

Creatinine4

Tissue2

Increases2

Outcomes1

Fail1

Lung2

Function11

Dialysis1

Health16

Researchers found2

CONCLUSIONS1

Medications1

Pathological1

Diabetes3

20171

Toxins3

Liver or kidney1

Doses3

Nephrotoxicity2

People with kidney4

Harm1