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  • investigate
  • The first large study designed to investigate this association confirmed an increased risk to develop ITP in coeliac patients and vice versa [ 20 ]. (hindawi.com)
  • The purpose of the present study was to investigate if YKL-40 is also a significant factor in osteoarthritis (OA) by assessing associations of YKL-40 with mediators related to the pathogenesis of OA: cartilage destructing matrix metalloproteinases (MMPs) and proinflammatory cytokines interleukin-6 (IL-6) and interleukin-17 (IL-17). (hindawi.com)
  • In the present study, we aimed to address the hypothesis by measuring the simultaneous levels of YKL-40 in plasma and in synovial fluid as well as to investigate whether YKL-40 in SF is associated with inflammatory and catabolic factors MMP-1, MMP-3, IL-6, and IL-17 in patients with osteoarthritis. (hindawi.com)
  • general
  • The prevalence of CD worldwide has been estimated between 0.5% and 1% [ 2 , 3 ], in particular, a recent study based on data from the Italian general population reported a prevalence of 0.7% [ 4 ]. (hindawi.com)
  • patients
  • A greater frequency of ITP in coeliac patients and vice versa was observed in our study, suggesting an increased risk for patients of developing both disorders. (hindawi.com)
  • were not able to find any case of CD [ 21 ], while in a more recent study, Sarbay and colleagues observed one case of CD in a group of 29 ITP patients [ 22 ]. (hindawi.com)
  • The aim of this study was to evaluate the frequency of ITP in a cohort of coeliac patients and conversely, the occurrence of CD in patients affected by ITP. (hindawi.com)
  • Consecutive patients with a diagnosis of CD attending the Gastrointestinal Service at the Clinica Medica, and patients followed for ITP attending the Hematological Service were enrolled in the study from January 2016 to December 2017. (hindawi.com)
  • Moreover, patients with ITP were studied for CD according to the current guidelines. (hindawi.com)
  • The patients in the present study fulfilled the American College of Rheumatology classification for OA [ 14 ]. (hindawi.com)
  • psychological
  • If hypotheses are supported, the study may benefit participants by reducing their psychological distress, increasing their well-being, and helping them better manage pain and aversive stimuli. (clinicaltrials.gov)
  • Potential risks associated with fMRI include ferromagnetic collision, neurostimulation effects, and psychological discomfort. (clinicaltrials.gov)
  • Potential risks to subjects include slight potential discomfort in providing saliva samples, discomfort of painful thermal stimulation, stress associated with the Trier Social Stress Test, some psychological discomfort from viewing disturbing photographs as part of the compassion fMRI study, and breach of confidentiality. (clinicaltrials.gov)