Studies coenzymes. Medical search. Frequent questions

SourceOne Global Partners has announced that the peer-reviewed journal, Alternative Therapies in Health and Medicine, has published the results of a double-blind study comparing the bioavailability of patented CoQsource® to that of three other "bio-enhanced" CoQ10 formulations. (newhope.com)
According to Dr. Zheng-Xian Liu, lead author of the study and author of more than 60 other peer-reviewed published studies, the scientific and medical community has emphasized the importance in supplementing with CoQ10 and improving the uptake and bioavailability in CoQ10 formulations, especially with the dramatic increase in the number of people taking stain drugs. (newhope.com)
This study showed higher relative bioavailability not compared to CoQ10 powder, but compared to patented soft gel enhanced absorption delivery systems. (newhope.com)
In humans, the most common form is coenzyme Q10 (which is also called CoQ10 (/ˌkoʊkjuːˈtɛn/) and ubiquinone-10. (wikipedia.org)
Coenzyme Q10 (CoQ10) helps generate energy in human cells. (medicalnewstoday.com)
A 2018 study found that CoQ10 could improve the response of the ovaries to stimulation in women undergoing in vitro fertilization (IVF). (medicalnewstoday.com)
Coenzyme Q10 , or CoQ10 , is a naturally occurring substance, found in all the cells of our body. (hdbuzz.net)
In 1996, physicians led by Dr. Ira Shoulson published a small study of CoQ10 in human HD patients. (hdbuzz.net)
The results of a bigger trial of CoQ10 in HD were reported by the Huntington Study Group in 2001. (hdbuzz.net)
There are a few possible explanations for why the results with CoQ10 failed to translate from mouse to human studies. (hdbuzz.net)
A large Parkinson's disease study, published in 2002, suggested that very large doses of CoQ10 (as high as 1,200 mg per day) were tolerated by patients with this disease. (hdbuzz.net)
In a small human study, published in 2010, researchers observed that human HD patients were able to take up to 3,600 mg a day of CoQ10 without important negative effects. (hdbuzz.net)
This study would use a very large dose of CoQ10 (2,400 mg a day), and treat volunteers for a whopping 5 years . (hdbuzz.net)
In some studies, CoQ10 seems to help HD mice, but it doesn't work in human HD patients. (hdbuzz.net)
Coenzyme Q10 (CoQ10) may represent a safe therapeutic option for patients with HF. (nih.gov)
Although having limitations, this study has renewed interest in evaluating CoQ10 supplementation in patients with HF. (nih.gov)
Studies have shown that coenzyme Q10 (CoQ10) has a beneficial effect on patients with heart failure. (indexindex.com)
The purpose of the present double-blind, placebo-controlled, randomized study was to assess the effect of CoQ10 on patients with end-stage heart failure and to determine if CoQ10 can improve the pharmacological bridge to heart transplantation. (indexindex.com)
Primary deficiency of coenzyme Q10 (CoQ10 ubiquinone), is classified as a mitochondrial respiratory chain disorder with phenotypic variability. (tau.ac.il)
The selected patients in the study group (group-A) were given Clomiphene citrate 100mg/day from cycle days 2-6 for 45 days (2 cycles) and CoQ10 in a dose of 50mg soft gel capsules thrice per day starting at cycle day-2, until HCG administration. (org.pk)
Studies show that several different psychiatric medications, including antidepressants and antipsychotics, deplete CoQ10. (davidwolfe.com)
Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant found in every cell in the body. (earthclinic.com)
Several studies have demonstrated the effectiveness of CoQ10 supplements in improving gum health. (earthclinic.com)
One study found that supplementing with 50 mg of CoQ10 daily for three months reduced gum inflammation and bleeding in individuals with periodontitis. (earthclinic.com)
Another study found that combining CoQ10 and vitamin E supplements improved gum health and reduced gum pocket depth in individuals with chronic periodontitis. (earthclinic.com)
Coenzyme Q10 (CoQ10) is a substance similar to a vitamin. (molecularlab.it)
Coenzyme Q10 (CoQ10) is required by every cell in our body and is key to the chemical reactions that produce cellular energy. (twofarmkids.com)
Natural interventions, such as vitamin D , calcium , ginkgo biloba , and coenzyme Q10 (CoQ10) have shown promise for the management of vertigo. (lifeextension.com)

Coenzyme Q is a coenzyme family that is ubiquitous in animals and most bacteria (hence its other name, ubiquinone). (wikipedia.org)
Coenzyme Q10 (ubiquinone) is an enzyme that is naturally produced in the body. (merckmanuals.com)
Coenzyme Q 10 is a member of the ubiquinone family of compounds. (oregonstate.edu)
Biochemist Anne-Louise Mortensen shows that serum Coenzyme Q10 levels above 3.0 micrograms per milliliter can be achieved through daily supplementation with 300 milligrams of a patented ubiquinone Coenzyme Q10 supplement. (q10facts.com)
Coenzyme Q10 ubiquinone (microorganism). (twofarmkids.com)

The levels of coenzyme Q10 seem to be lower in older people and in people with chronic diseases, such as heart problems, cancer, Parkinson disease, diabetes, HIV infection or AIDS, and muscular dystrophies. (merckmanuals.com)
Because people with some diseases have reduced levels of coenzyme Q10, scientists have studied whether coenzyme Q10 supplements have health benefits. (merckmanuals.com)
Studies have shown an association between low levels of coenzyme Q10 and increased fatigue. (medicalnewstoday.com)
The authors of a 2014 review stated that studies have consistently associated low levels of coenzyme Q10 with fatigue. (medicalnewstoday.com)
Adequate levels of Coenzyme Q10 are needed for the normal functioning of almost all cells and especially for the normal functioning of the heart muscle cells, which have a constant need for energy. (q10facts.com)
The Q-Symbio study results demonstrate that adjunctive treatment with Coenzyme Q10 addresses the problems caused by low levels of Coenzyme Q10 in heart muscle cells, thus helping the heart failure patients to produce the cellular energy that they need [Mortensen 2015]. (q10facts.com)
atorvastatin decreases levels of coenzyme Q10 by unspecified interaction mechanism. (medscape.com)

Research has shown that coenzyme Q10 may improve both physical performance and "subjective fatigue" in healthy people engaging in physical activity. (medicalnewstoday.com)

Endogenous synthesis and dietary intake provide sufficient coenzyme Q 10 to prevent deficiency in healthy people, although coenzyme Q 10 concentrations in tissues decline with age. (oregonstate.edu)
Deficiency of 3-methylglutaconyl-coenzyme A hydratase in two siblings with 3-methylglutaconic aciduria. (jci.org)
Primary coenzyme Q10 deficiency is a disorder that can affect many parts of the body, especially the brain, muscles, and kidneys. (medlineplus.gov)
As its name suggests, the disorder involves a shortage (deficiency) of a substance called coenzyme Q10. (medlineplus.gov)
The severity, combination of signs and symptoms, and age of onset of primary coenzyme Q10 deficiency vary widely. (medlineplus.gov)
A type of kidney dysfunction called nephrotic syndrome is another common feature of primary coenzyme Q10 deficiency. (medlineplus.gov)
can also occur in primary coenzyme Q10 deficiency. (medlineplus.gov)
The prevalence of primary coenzyme Q10 deficiency is thought to be less than 1 in 100,000 people. (medlineplus.gov)
Primary coenzyme Q10 deficiency is caused by mutations in genes that provide instructions for making proteins involved in the production (synthesis) of a molecule called coenzyme Q10. (medlineplus.gov)
Smaller numbers of mutations in other COQ genes have also been found to cause primary coenzyme Q10 deficiency. (medlineplus.gov)
Studies suggest that a shortage (deficiency) of coenzyme Q10 impairs oxidative phosphorylation and increases the vulnerability of cells to damage from free radicals. (medlineplus.gov)

The lysosomal membranes that separate those digestive enzymes from the rest of the cell contain relatively high concentrations of coenzyme Q 10 . (oregonstate.edu)
Coenzymes help enzymes work to help protect the heart and skeletal muscles. (molecularlab.it)

While statins may reduce coenzyme Q10 in the blood it is unclear if they reduce coenzyme Q10 in muscle. (wikipedia.org)
Proponents also claim that coenzyme Q10 can decrease the muscle symptoms that can result from taking statins. (merckmanuals.com)
The use of cholesterol -lowering medications called statins can decrease circulating coenzyme Q 10 concentrations. (oregonstate.edu)
Studies have suggested that statins may inhibit tumor cell growth and possibly prevent carcinogenesis. (cdc.gov)
Our study demonstrated that persistent use of statins is associated with a lower overall cancer risk and particularly the risk of incident hematopoietic malignancies. (cdc.gov)
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) effectively reduce cholesterol levels and decrease the incidence of cardiovascular and cerebrovascular events (4). (cdc.gov)
Statins have been associated with a significantly lower risk of breast (8), colorectal (9), and lymph cancers (10-12) in several observational studies (10,13). (cdc.gov)
Most previous observational studies have been limited by a small number of cases, short follow-up period, unverified self-reports on use and consistency of statins therapy, and no assessment of statins efficacy. (cdc.gov)
Our previous study (14) demonstrated a strong negative association between persistent use of statins and all-cause mortality reduction among patients with and without a history of coronary heart disease (CHD). (cdc.gov)
The objective of this study was to investigate the association between persistent use of statins and the risk of overall and site-specific cancer in adults, to assess dose-response relationship, and to examine the effects of varying types of statins. (cdc.gov)

A 2016 study found that men with obesity who consumed vitamin C had improved sperm concentration and mobility. (medicalnewstoday.com)
All animals, including humans, can synthesize ubiquinones, hence, coenzyme Q 10 is not considered a vitamin (1) . (oregonstate.edu)
One study found that supplementing with 60 mg of vitamin C daily for six months improved gum health and reduced gum bleeding in individuals with gingivitis, a mild form of gum disease. (earthclinic.com)
Another study found that individuals with periodontitis who received a high dose of vitamin C (1,000 mg) daily for six months experienced a significant reduction in gum bleeding and pocket depth. (earthclinic.com)
Numerous studies suggest positive association between taking vitamin and mineral supplements, and heart disease prevention. (molecularlab.it)
Just like vitamin E, coenzyme Q10 is particularly good at protecting low-density lipoproteins (the bad cholesterol) from oxidation, a process that contributes to plaque build up in the arteries. (twofarmkids.com)
1975. Drug-biomolecule interations: Drug toxicity and vitamin coenzyme depletion. (cdc.gov)

Coenzyme Q10 is an enzyme in the mitochondria, which are the parts of cells that generate energy. (medicalnewstoday.com)
Coenzyme Q10 helps mitochondria make energy. (hdbuzz.net)

Coenzyme Q10 is said to be useful because of its antioxidant effect and role in energy metabolism. (merckmanuals.com)
In its reduced form (CoQ 10 H 2 ), coenzyme Q 10 is an effective fat-soluble antioxidant that protects cell membranes and lipoproteins from oxidation . (oregonstate.edu)
In cell membranes, coenzyme Q10 acts as an antioxidant, protecting cells from damage caused by unstable oxygen-containing molecules (free radicals), which are byproducts of energy production. (medlineplus.gov)
Coenzyme Q10 is an antioxidant that your body produces. (romanfitnesssystems.com)

While there are numerous claims about the benefits of such supplements, it is essential to remember that the United States Food and Drug Administration (FDA) do not require most supplements to prove their effectiveness in clinical studies. (medicalnewstoday.com)
Coenzyme Q10 supplements may interact with some antihypertensive (those that lower blood pressure) and chemotherapy drugs. (merckmanuals.com)
Although coenzyme Q 10 supplements are relatively safe, they may decrease the anticoagulant efficacy of warfarin. (oregonstate.edu)
Another study found that a combination of omega-3 fatty acid supplements and traditional periodontal therapy improved gum health and reduced gum pocket depth in individuals with periodontitis. (earthclinic.com)

The therapeutic efficacy of coenzyme Q10 on patients with cardiac failure remains controversial. (biomedcentral.com)

There are currently no proven therapeutic benefits of coenzyme Q 10 supplementation in diabetes mellitus , neurodegenerative diseases , inherited ataxias , or breast cancer . (oregonstate.edu)
Coenzyme Q10 treatment lowered the risk of death from all-causes, the risk of death from cardiovascular diseases, and the risk of hospitalization to a greater extent in the European heart failure patients. (q10facts.com)

In contrast to other drug therapies that are designed to block or reduce some aspect of cellular activity, Coenzyme Q10 supplementation improves cell function. (q10facts.com)

The patients were randomly assigned to an active treatment group receiving 100 milligrams of Coenzyme Q10 three times a day or to a group taking matching placebos three times a day [Mortensen 2014]. (q10facts.com)
Aware that there have been geographical variations in the patient characteristics and in the management of patients in heart failure studies, the Danish bio-chemist Anne Louise Mortensen separated out the data for the European heart failure patients who participated in the Q-Symbio study. (q10facts.com)
Her purpose was to compare the response of the more homogeneous European sub-population of the Q-Symbio study with the response of the total Q-Symbio study population [Mortensen 2018]. (q10facts.com)
In contrast, the corresponding serum Coenzyme Q10 levels in the total Q-Symbio study group were 3.01 mcg/ml at 3 months and 2.2 mcg/ml at 2 years [Mortensen 2018]. (q10facts.com)

The coenzyme nicotinamide adenine dinucleotide (NADH) has been used in an open label trial as medication in 205 patients suffering from depression with various clinical symptoms. (enadastudies.com)
This observation prompted us to study the clinical effect of NADH on patients suffering from psychic depression. (enadastudies.com)
The Q-Symbio randomized, double-blind , placebo-controlled study of the effect of Coenzyme Q10 adjunctive treatment on the symptoms, adverse cardiovascular events, and survival of chronic heart failure patients is the single best Coenzyme Q10 clinical study that we have. (q10facts.com)
In this study, we demonstrate that ATP citrate lyase (Acly), which metabolizes citrate to generate cytosolic acetyl-CoA and is of clinical interest, can regulate chromatin accessibility to limit myeloid differentiation. (nih.gov)
In summary, herb-warfarin interaction, especially the clinical effects of herbs on warfarin therapy should be further investigated through multicenter studies with larger sample sizes. (hindawi.com)
The potency shown in clinical use boosts the studies on the mechanisms of warfarin anticoagulation. (hindawi.com)
We pooled previous clinical studies to re-evaluate the efficacy of coenzyme Q10 in patients with cardiac failure. (biomedcentral.com)
We pooled previous studies to evaluate the efficacy of coenzyme Q10 in heart failure treatment to provide a data-driven concept for clinical practice. (biomedcentral.com)
Clinical study in which a prospectively planned opportunity is included to modify trial designs and hypotheses based on analysis of data from subjects in the study. (bvsalud.org)
Other studies may be obtained on the basis of clinical findings or in individuals with suspected secondary hypertension and/or evidence of target-organ disease, such as CBC, chest radiograph, uric acid, and urine microalbumin. (medscape.com)

The pooled risk ratios (RRs) and standardized mean difference (SMD) were used to assess the efficacy of coenzyme Q10. (biomedcentral.com)
No significant differences between the efficacy of the administration of coenzyme Q10 and placebo in the endpoints of left heart ejection fraction and NYHA classification were observed. (biomedcentral.com)

Decanoyl coenzyme A (Decanoyl CoA) is coupled with S-adenosylmethionine (SAM) by Vibrio cholera CqsA enzyme to produce a potent quorum-sensing molecule, 3-aminotridec-2-en-4-one (Ea-CAI-1. (sigmaaldrich.com)
The coenzyme Q10 molecule has several critical functions in cells throughout the body. (medlineplus.gov)
A molecule of coenzyme A carrying an acetyl group is also referred to as acetyl-CoA. (dadamo.com)

Coenzyme Q (CoQ) is essential for the mitochondrial respiratory chain. (ironmagazine.com)

In addition to its role in ATP synthesis, mitochondrial coenzyme Q 10 mediates the oxidation of dihydroorotate to orotate in the de novo pyrimidine synthesis. (oregonstate.edu)
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidization of fatty acids, and the oxidation of pyruvate in the citric acid cycle. (dadamo.com)
In this study, we explored the catalyst‐free one‐pot multi‐component synthesis of 1,4‐dihydropyridine derivatives by following green chemistry protocol. (researchgate.net)

Coenzyme Q10 may increase the risk of blood clots in people who take the anticoagulant warfarin by decreasing warfarin 's effectiveness. (merckmanuals.com)
coenzyme Q10, warfarin. (medscape.com)
In absence of good evidence, speculation has taken its place, and poor quality of available information in turn restricts future study of herb-warfarin interaction. (hindawi.com)

Oral supplementation of coenzyme Q 10 increases coenzyme Q 10 concentrations in plasma and lipoproteins, but it is unclear whether concentrations in peripheral tissues are increased, especially in healthy individuals. (oregonstate.edu)
coenzyme Q10 increases effects of insulin aspart by pharmacodynamic synergism. (medscape.com)

As part of the mitochondrial electron transport chain , coenzyme Q 10 accepts electrons from reducing equivalents generated during fatty acid and glucose metabolism and then transfers them to electron acceptors. (oregonstate.edu)
Coenzyme A is very central to the balance between carbohydrate metabolism and fat metabolism. (dadamo.com)

Stefely, J. A. & Pagliarini, D. J. Biochemistry of mitochondrial coenzyme Q biosynthesis. (nature.com)

The individual symptoms experienced by ill Gulf War veterans can vary from person to person, but overall the types of symptoms reported are similar in the many groups of ill veterans that have been studied since the war. (cdc.gov)

The Coenzyme Q10 or placebo treatment was given in addition to the conventional heart failure medication. (q10facts.com)
Patients with heart failure who used coenzyme Q10 had lower mortality and a higher exercise capacity improvement than the placebo. (greenmedinfo.com)

Interestingly, the serum Coenzyme Q10 concentrations of the European heart failure patients averaged 3.42 micrograms per milliliter (mcg/ml) at 3 months and 3.55 mcg/ml at 2 years of the study. (q10facts.com)

What drug interactions occur with coenzyme Q10? (merckmanuals.com)

The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study. (ox.ac.uk)
This study investigated the effect of the trans-resveratrol supplementation on the cardiac oxidative stress in rats exposed to cigarette smoke. (bvsalud.org)

Oral high-dose coenzyme Q 10 is usually effective to treat mitochondrial disorders that are caused by mutations in coenzyme Q 10 biosynthetic genes . (oregonstate.edu)

Design Retrospective observational analysis of administrative databases, using nine population based cohort studies and meta-analysis. (bmj.com)

An epidemiologic study in northern Finland found the prevalence of the A3243G MELAS mutation (responsible for 80% of cases) to be 16.3 per 100,000. (medscape.com)

A lack of functional protein produced from any one of the COQ genes decreases the normal production of coenzyme Q10. (medlineplus.gov)

Coenzyme Q10 can prolong C. elegans lifespan by lowering oxidative stress. (ironmagazine.com)

Through a complex reaction, pyruvate is decarboxylated and turned into acetaldehyde, then attached to coenzyme A while NAD+ is subsequently reduced to NADH and H+. (dadamo.com)

In a double-blind study of patients with chronic heart failure, supplementation with fish oil resulted in a small but statistically significant decrease in the number of patients who died or were hospitalized for cardiovascular reasons. (molecularlab.it)

The aim of this study was to use the metabolic tracer hyperpolarized [2-(13)C]pyruvate with magnetic resonance spectroscopy to determine whether carnitine acetyltransferase facilitates carbohydrate oxidation in the heart. (ox.ac.uk)

The rate of emergency department visits also increased significantly, according to the study, rising from 190.1 visits per 100,000 population in 2006 to 238.5 visits per 100,000 population in 2011. (medscape.com)

Coenzyme Q10 treatment lowered the risk of major adverse cardiovascular events to a greater extent in the European heart failure patients. (q10facts.com)
The current study aspires to find out whether irradiated powder of hibiscus has a protective role against adverse effects of repeated use of frying edible oil. (bvsalud.org)

In addition to being naturally made in the body, coenzyme Q10 is in foods such as meat, fish, and vegetable oils. (merckmanuals.com)

The research on whether coenzyme Q10 supplementation is useful for athletes has produced mixed results. (medicalnewstoday.com)
The remarkable results on yield, process, development of DHPs, anti‐proliferative activity, structure determination and single crystal study of DHPs discussed in this article. (researchgate.net)
Click the name of each supplement to see more information, including results from studies, showing uses and doses. (molecularlab.it)
The evaluation of hypertension involves accurately measuring the patient's blood pressure, performing a focused medical history and physical examination, and obtaining results of routine laboratory studies. (medscape.com)

of heart Failure Treatment study. (qxmd.com)
There is some evidence to suggest that coenzyme Q 10 supplementation may be a useful adjunct to conventional medical therapy for congestive heart failure and in patients undergoing coronary artery bypass graft surgery. (oregonstate.edu)
The Q-Symbio study was a two-year multi-center study enrolling 420 patients with moderate to severe heart failure. (q10facts.com)
Coenzyme Q10 treatment increased left ventricle ejection fraction to a greater extent in the European heart failure patients. (q10facts.com)
The study group showed significant improvement in the 6-min walk test and a decrease in dyspnea, New York Heart Association (NYHA) classification, nocturia, and fatigue. (indexindex.com)
Coenzyme Q10 may serve as an optional addition to the pharmacologic armamentarium of patients with end-stage heart failure. (indexindex.com)
Association between Micronutrients and Heart Rate Variability: A Review of Human Studies. (wellnessresources.com)
Studies also evidenced that the concentration of coenzyme Q10 in the plasma of patients with heart failure is an independent predictor of heart failure death [ 6 ]. (biomedcentral.com)
Studies indicate that lowering a patient's blood pressure from 160/90 to 140/80 mmHg may decrease risk of heart disease by more than 30 percent. (massagetoday.com)

Reviews, meta-analyses, and observational studies were excluded. (biomedcentral.com)

A synthetic form of coenzyme Q10 is available as a dietary supplement. (merckmanuals.com)
In an open label trial 205 patients suffering from depression have been treated with the coenzyme B- Nicotinamide adenine dinucleotide in its reduced form (NADM. (enadastudies.com)
The conversion of energy from carbohydrates and fats to ATP , the form of energy used by cells, requires the presence of coenzyme Q 10 in the inner mitochondrial membrane. (oregonstate.edu)

For example, a 2012 study of moderately trained men found no evidence that it benefitted their exercise capacity. (medicalnewstoday.com)

The objective of this study was to investigate the association between persistent statin use and the risk of primary cancer in adults. (cdc.gov)

Blood and liver samples were collected for biochemical analyses as well as histological study. (bvsalud.org)

A new assay for 3-methylglutaconyl-coenzyme A (CoA) hydratase has been developed in which the substrate, [5-14C]3-methylglutaconyl-CoA, was synthesized using 3-methylcrotonyl-CoA carboxylase purified from bovine kidney. (jci.org)
Decanoyl coenzyme A is a substrate for acyltransferase. (sigmaaldrich.com)

Some studies have linked oxidative damage to Parkinson's disease. (michaeljfox.org)

Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. (qxmd.com)
This retrospective study was conducted by using the computerized data sets of a large health maintenance organization (HMO) in Israel. (cdc.gov)

Coenzyme Q10 supplementation may reduce the frequency of migraine attacks per month. (greenmedinfo.com)

Coenzyme Q 10 is a fat-soluble compound that is synthesized by the body and can be obtained from the diet. (oregonstate.edu)
At the end of the study, body composition was measured in all the rats, and they were classified as carbohydrate resistant (CR) or carbohydrate sensitive (CS) according to their adiposity. (frontiersin.org)
Previous studies have shown that feeding rats with a standard low-fat HC starch based diet [conforming to the AIN-93 recommendations for rodents ( 15 )], which was expected to induce a moderate glycemic index, was able to generate differences in adiposity gain, although partly hidden by rather small differences in overall body weight gain ( 16 - 18 ). (frontiersin.org)

Coenzyme Q10 is also involved in producing pyrimidines, which are building blocks of DNA, its chemical cousin RNA, and molecules such as ATP and GTP that serve as energy sources in the cell. (medlineplus.gov)
Coenzyme Q10 plays a key role in the production of energy. (davidwolfe.com)

Anatomy5

Organisms20

Diseases2

Chemicals and Drugs170

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Phenomena and Processes35

Disciplines and Occupations1

Technology, Industry, Agriculture3

Information Science3

Health Care1

CoQ1028

Ubiquinone5

Levels of coenzyme7

Shown that coenzyme1

Deficiency11

Enzymes2

Statins10

Vitamin7

Mitochondria2

Antioxidant4

Supplements4

Therapeutic efficacy1

Diseases2

Supplementation improves1

Mortensen4

Clinical10

Efficacy2

Molecule3

Mitochondrial respiratory chain1

Synthesis3

Warfarin3

Increases2

Metabolism2

Biochemistry1

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Placebo2

Concentrations1

Drug interactions1

Cardiac2

Mutations1

Meta Analysis1

Prevalence1

Genes1

Oxidative stress1

NADH1

Chronic heart1

Oxidation1

100,0001

Adverse2

Naturally1

Results4

Heart9

Observational studies1

Form3

Evidence1

Primary1

Biochemical1

Substrate2

Parkinson's1

Retrospective study2

Frequency1

Body3

Energy2