Structural and functional brain functional magnetic resonance imaging brain multimodal imaging. Medical search. Frequent questions

First, the data on structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) are preprocessed to remove the influence resulting from the differences in image size and shape of different individuals, head movement, noise, and so on. (hindawi.com)
In addition, the PCANet network is applied to the brain function connection analysis, and the features on fMRI data are obtained. (hindawi.com)
At present, structural MRI (sMRI) and functional MRI (fMRI) are widely used in the diagnosis of Alzheimer's disease (AD). (hindawi.com)
fMRI is used to measure the changes in hemodynamics caused by neuronal activity which can show the location and extent of brain activation and can detect dynamic changes in the brain over a period of time. (hindawi.com)
Deep learning algorithms are also widely used in fMRI-assisted diagnosis of brain diseases. (hindawi.com)
Neuroimaging experiments (using fMRI, PET, or arterial spin labeling) reporting whole-brain results in adults with BD and controls published from December 1999-June 18, 2019 were identified via PubMed search. (nature.com)
BACKGROUND: Functional magnetic resonance imaging (fMRI) has great potential for measuring mechanisms of functional changes in Alzheimer's disease (AD) and mild cognitive impairment, but task fMRI studies have produced conflicting results, partly due to failure to account for underlying morphological changes and to variations in patients' ability to perform the tasks. (ox.ac.uk)
Resting fMRI has potential for assessing brain function independently from a task, but greater understanding of how networks of resting functional connectivity relate to the functioning of the brain is needed. (ox.ac.uk)
METHODS: Eighty elderly (25 control subjects, 25 mild cognitive impairment, 30 AD) underwent a combined multimodal magnetic resonance imaging protocol including task fMRI and resting fMRI. (ox.ac.uk)
Structural and physiological confounds were modeled for both fMRI modalities. (ox.ac.uk)
this overlapped with increased resting fMRI functional connectivity in the same regions. (ox.ac.uk)
CONCLUSIONS: Our results show that task fMRI and resting fMRI are sensitive markers of residual ability over the known changes in brain morphology and cognition occurring in AD and suggest that resting fMRI has a potential to measure the effect of new treatments. (ox.ac.uk)
Here, we aggregate the largest, quality-controlled multimodal neuroimaging dataset from 119 global sites, including 33,809 task-free fMRI and structural MRI scans from 32,328 individuals ranging in age from 32 postmenstrual weeks to 80 years. (bvsalud.org)
For each subject, we acquired high-resolution brain structural images and resting-state fMRI (rs-fMRI) data using a 3 T MRI scanner. (bvsalud.org)
The activity of each brain region can be converted into a simulated BOLD signal in order to calibrate the model against empirical data from functional magnetic resonance imaging (fMRI). (sfb1315.de)
The CNS-Lab specializes in experimental design, and data acquisition, analyses, and interpretation for clinical and non-clinical studies that employ functional magnetic resonance imaging (fMRI), perfusion MRI (arterial spin labeling techniques), and structural morphometry (e.g., volumetrics, cortical thickness, lesion quantification). (uga.edu)
Dr. Jiang's research focuses on multi-modal fMRI brain imaging technology in rodent models. (martinos.org)
Neuroimaging processing and analyses include modality-specific corrections for distortions and motion, brain segmentation and cortical surface reconstruction derived from structural magnetic resonance imaging (sMRI), analysis of brain microstructure using diffusion MRI (dMRI), task-related analysis of functional MRI (fMRI), and functional connectivity analysis of resting-state fMRI. (colorado.edu)
Several NMR methods are also studied to measure molecular targets (magnetic resonance spectroscopy (MRS)), local neuronal activity (functional MRI (fMRI)), and brain structure (structural MRI). (nih.gov)
Most MRI/fMRI studies are carried out on the 3 and 7 Tesla magnets at the Functional Magnetic Resonance Imaging Core Facility or Clinical Center Radiology Department. (nih.gov)
Brain connectivity can be divided into functional connectivity, where spontaneous temporal synchronisations between brain regions are measured using fMRI with subjects scanned at rest, and structural connectivity, measured using diffusion MRI (dMRI), which images the physical connections between brain regions based on how water molecules diffuse within white matter tracts. (biorxiv.org)
A brain and body imaging extension will scan 100,000 participants by 2020, with brain imaging including three structural modalities, resting and task fMRI, and diffusion MRI 4 ( Supplementary Table 1 ). (biorxiv.org)
Structural modes of variation also replicate the fine-grained functional architecture seen in eight well defined visual areas in both task and resting-state fMRI. (nih.gov)
Combining graph neural fields with appropriate observation models allows for estimating model parameters from experimental data as obtained from electroencephalography (EEG), magnetoencephalography (MEG), or functional magnetic resonance imaging (fMRI). (ox.ac.uk)
We show that the model equilibrium fluctuations can reproduce the empirically observed harmonic power spectrum of resting-state fMRI data, and predict its functional connectivity, with a high level of detail. (ox.ac.uk)
With functional MRI (fMRI) or structural MRI (sMRI), studies have identified neurophysiological deficits in patients' brain from different perspective. (unm.edu)
structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) were used to assess brain structure. (psychnews.org)

Multimodal integration of functional and structural brain connectivity. (upm.es)
Specifically, members of the lab are using multi-modal magnetic resonance imaging (MRI) to describe altered connectivity among hippocampus sub-regions, associations between hippocampus size and treatment outcome and a series of measurable, functional and structural changes in the brain of PTSD patients following treatment. (wikipedia.org)
This meta-analysis aims to comprehensively reassess brain activation and connectivity in BD in order to identify replicable differences that converge across and within resting-state, cognitive, and emotional neuroimaging experiments. (nature.com)
Resting functional connectivity reveals residual functional activity in Alzheimer's disease. (ox.ac.uk)
By taking the identified structural clusters as seeds, we performed seed-based functional connectivity (FC) analyses to determine the regions with abnormal FC in the patients. (bvsalud.org)
Neuroimaging studies have identified significant differences in brain structure, function, and connectivity between endurance runners and healthy controls. (bvsalud.org)
In a whole-brain network model, brain regions are connected with each other based on biologically informed structural connectivity, i.e. the connectome of the brain. (sfb1315.de)
Cortical thickness, mean diffusivity, and fractional anisotropy were estimated at each of 308 cortical regions, as well as functional and structural connectivity between each pair of regions. (maastrichtuniversity.nl)
RESULTS: In both principal studies, the most informative metric was functional MRI connectivity: The areas under the receiver operating characteristic curve were 88% and 76%, respectively. (maastrichtuniversity.nl)
CONCLUSIONS: ML most accurately distinguished cases from controls by a replicable pattern of functional MRI connectivity features, highlighting abnormal hubness of cortical nodes in an anatomical pattern consistent with the concept of psychosis as a disorder of network development. (maastrichtuniversity.nl)
Correlation analysis revealed a positive association between covariation in thickness and functional connectivity in especially the theta band in MS patients, and these results could not be explained by simple regional gray matter thickness measurements. (utwente.nl)
This study is a first multimodal graph analysis in a sample of MS patients, and our results suggest that a disruption of gray matter network topology is important to understand alterations in functional connectivity in MS as regional gray matter fails to take into account the inherent connectivity structure of the brain. (utwente.nl)
Aberrant functional connectivity between reward and inhibitory control networks in pre-adolescent binge eating disorder Psychol Med. (usc.edu)
Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRß, a marker of blood brain barrier breakdown, in older adults Res Sq. 2023 Mar 07. (usc.edu)
An element of great interest in functional connectivity is 'homotopic connectivity' (HC), namely the connectivity between two mirrored areas of the two hemispheres, mainly mediated by the fibers of the corpus callosum. (springer.com)
Two properties were suggested to characterize brain connectivity: segregation and integration (Sporns, 2013 ). (springer.com)
HC refers to the (structural or functional) connectivity between two homologous areas of the two hemispheres, mainly mediated by the fibers of the corpus callosum (Goldstein et al. (springer.com)
Life stress also differentially affected, as a function of serotonin transporter genotype, functional connectivity of the amygdala and hippocampus with a wide network of other regions, as well as gray matter structural features, and affected individuals' level of rumination. (dericbownds.net)
We further reveal fine-grained anatomical signatures of functional connectivity. (nih.gov)
In summary, our results demonstrate that the relationship between structural and functional connectivity is fine-grained, widespread across the entire brain, and driven by covariation in cortical area, i.e. likely differences in shape, depth, or number of foldings. (nih.gov)
Whole-brain modelling of brain activity combines structural connectivity with local dynamical models to provide insight into the large-scale functional organization of the human brain. (ox.ac.uk)
We obtain analytic predictions for harmonic and temporal power spectra, as well as functional connectivity and coherence matrices, of graph neural fields, with a technique dubbed CHAOSS (shorthand for Connectome-Harmonic Analysis Of Spatiotemporal Spectra). (ox.ac.uk)
Functional connectivity (FC) analysis is an approach that measures functional integration in brains. (unm.edu)
Secondly, we applied graph analysis on functional network connectivity (FNC) to differentiate BD and MDD during resting-state. (unm.edu)
Decreased functional connectivity of the insula within the salience network as an indicator for prospective insufficient response to antidepressants. (nesda.nl)
We computed the activity maps unique to switch vs. stay trials and all switch dimensions, then evaluated functional connectivity under these switch conditions by computing the pairwise mutual information functional connectivity (miFC) between regional timeseries. (imperial.ac.uk)

A fusion analysis of structural and functional modalities may better reveal the disease biomarker specific to the MDD disease. (bvsalud.org)
The proposed multimodal self- supervised learning yields representations with improved classification performance for both modalities. (deepai.org)
Magnetic resonance imaging (MRI) data, which are available in a large variety of modalities, has led to challenges regarding how to best utilize and interpret combined information for diagnostic purposes. (bactra.org)
Great progress has been made in registering different MRI modalities via the use of brain atlases, so that regional information is also maintained. (bactra.org)
Structural MRI measures of brain anatomy include tissue and structure volumes, such as total grey matter volume and hippocampal volume, while other MRI modalities allow the mapping of different biological markers such as venous vasculature, microbleeds and aspects of white matter (WM) micro-structure. (biorxiv.org)
A fully automated image processing pipeline removes artefacts and renders images comparable across modalities and participants. (biorxiv.org)
Traditional imaging modalities, such as conventional magnetic resonance imaging (MRI), have played a crucial role in the diagnosis and monitoring of brain tumors. (debuglies.com)
Graph analysis reveals the interaction among brain regions based on graph theory, while the multimodal fusion framework enables us to utilize the strength of different imaging modalities through joint analysis. (unm.edu)
Medical imaging contains multiple imaging sequences or modalities, such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET), providing complementary information ( 5 - 8 ). (frontiersin.org)
A variety of imaging modalities, including structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET) studies of cerebral metabolism, have shown characteristic changes in the brain of patients with Alzheimer disease in prodromal and even presymptomatic states. (medscape.com)

We aim to discriminate between groups and predict clinical and functional outcomes based on a combination of clinical, neurocognitive, neuroimaging (functional, structural magnetic resonance imaging and magnetic resonance spectroscopy) and blood-based markers (genetics, autoimmunity, biological stress response, oxidative stress). (clinicbarcelona.org)
use the functional near-infrared spectroscopy based cerebral blood flow imaging method to estimate the hemodynamic response function of each ROI, in order to study the brain networks that are activated during the processing of self-esteem related information [9]. (researchsquare.com)
The Section on Magnetic Resonance Spectroscopy (MRS) develops and applies both high-resolution and in vivo MRS and imaging techniques. (nih.gov)
Numerous studies are under way to identify specific imaging markers for different types of dementia, including cerebral volumetric measurements, diffusion imaging, spectroscopy, very-high-field MRI scans of senile plaques, and PET scan markers of senile plaques. (medscape.com)
Assessment of brain metabolite correlates of adeno-associated virus-mediated over-expression of human alpha-synuclein in cortical neurons by in vivo (1) H-MR spectroscopy at 9.4 T. (lu.se)

Combining state-of-the-art statistics with bioinformatic knowledge bases, we will provide services to support researchers and clinicians interested in integrating clinical and biological data (e.g. microbiota, metabolites, metagenomics, transcriptomics, epigenetics, multimodal neuroimaging data obtained from human and animal studies). (uclahealth.org)
Important tools here are innovative neuroimaging, which includes, for example, structural and functional Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and multimodal neuroimaging, as well as High Performance Computing (HPC), which enable the exploration of the brain as the biological basis of our being and an information-processing system in a multiscale approach. (fz-juelich.de)
We follow-up youth at different stages of risk for psychosis, defined according to genetic and/or clinical criteria, in comparison with healthy volunteers and with patients with early onset psychosis, using clinical, neurocognitive and neuroimaging markers, aiming to understand the relationship between brain structure and function and clinical and cognitive phenotype. (clinicbarcelona.org)
This work has elucidated structural and functional neuroimaging findings are related to depression and treatment outcomes. (vumc.org)
Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a limited view of the highly complex brain. (deepai.org)
This work presents a novel multi-scale coordinated framework for learning multiple representations from multimodal neuroimaging data. (deepai.org)
I examine brain-behavior relationships in clinical populations using cognitive and affective neuroscience techniques, particularly multimodal neuroimaging and neuropsychological assessments. (uga.edu)
It is a neuroimaging data analysis and neuropsychological assessment laboratory affiliated with the Clinical Psychology and Brain and Behavioral Science Programs in the Department of Psychology and the interdisciplinary Neuroscience Program at UGA. (uga.edu)
The CNS-Lab integrates multimodal neuroimaging and neuropsychological assessments with other clinical research methodology to examine brain-behavior relationships. (uga.edu)
Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability medRxiv. (usc.edu)
Here, we describe the baseline neuroimaging processing and subject-level analysis methods used by the ABCD DAIC in the centralized processing and extraction of neuroanatomical and functional imaging phenotypes. (colorado.edu)
Established by the NIMH in 2000, the Molecular Imaging Branch (MIB) uses a variety of neuroimaging techniques to explore molecular and chemical mechanisms associated with neural function in health and disease. (nih.gov)
The Neuroimaging Section applies both PET and NMR imaging technologies to investigate the neurobiological bases of neuropsychiatric disorders. (nih.gov)
2017 ). The presence of functional HC has been also confirmed by numerous meta-analytic studies based on neuroimaging data and by applying different methods (Laird et al. (springer.com)
Affiliated with the Montreal Neurological Institute (The Neuro) at McGill University, the McConnell Brain Imaging Centre (BIC) is a one-of-a-kind, multidisciplinary neuroimaging centre recognized internationally for its advances in the acquisition and analysis of multimodal imaging data, as well as for its groundbreaking discoveries related to structural, functional and molecular mechanisms of the healthy and diseased brain. (mcgill.ca)
Over the last decades, non-invasive in-vivo neuroimaging techniques such as magnetic resonance imaging (MRI) have been increasingly applied to measure structure and function in human brains. (unm.edu)
The results provide evidence that multimodal neuroimaging data, as well as neuropsychological testing, can be used to generate predictions of future behaviors with [possibly] significantly better accuracy than demographic information alone," the authors wrote. (psychnews.org)
Routine structural neuroimaging evaluation has long been based on nonspecific features such as atrophy, which is a late feature in the progression of the disease. (medscape.com)
MRI can be considered the preferred neuroimaging examination for Alzheimer disease because it allows accurate measurement of the 3-dimensional (3D) volume of brain structures, especially the size of the hippocampus and related regions. (medscape.com)
Neuroimaging is widely believed to be generally useful for excluding reversible causes of dementia syndrome such as normal-pressure hydrocephalus, brain tumor, and subdural hematoma, and for excluding other likely causes of dementia such as cerebrovascular disease. (medscape.com)

Providing a realistic and biologically meaningful model of the human brain can be used as an innovative tool in basic research as well as in preclinical and clinical research, thereby contributing to the understanding of biological and cognitive information processing. (fz-juelich.de)
Self-supervised learning is crucial for clinical imaging applications, g. (deepai.org)
My research aims to establish reliable biomarkers for clinical services to predict individual disease stages of brain disorders, monitor treatment responses and develop novel interventions. (researchgate.net)
Background: Early psychosis in first-episode psychosis (FEP) and clinical high-risk (CHR) individuals has been associated with alterations in mean regional measures of brain morphology. (researchgate.net)
Examination of variability in brain morphology could assist in quantifying the degree of brain structural heterogeneity in clinical relative to healthy control (HC. (researchgate.net)
We investigated evidence for advanced brain ageing in adult SZ patients, and whether this was associated with clinical characteristics in a prospective meta-analytic study conducted by the ENIGMA Schizoph. (researchgate.net)
The Nguyen lab focuses on the development and clinical application of novel imaging techniques to characterize the cardiovascular system including MRI, optical, and PET. (martinos.org)
The study employs state-of-the-art multimodal brain imaging, cognitive and clinical assessments, bioassays, and careful assessment of substance use, environment, psychopathological symptoms, and social functioning. (colorado.edu)
Clinical characteristics with brain magnetic resonance imaging were evaluated in forty patients with NMOSD. (phoenixrising.me)
Medical image analysis is of tremendous importance in serving clinical diagnosis, treatment planning, as well as prognosis assessment. (frontiersin.org)
We present an integrated platform - uAI Research Portal (uRP), to achieve one-stop analyses of multimodal images such as CT, MRI, and PET for clinical research applications. (frontiersin.org)
Medical imaging is widely employed in clinical research to investigate effects on diagnosis, staging, treatment planning, and follow-up evaluations ( 1 - 4 ). (frontiersin.org)
The processing and quantitative analysis of medical images ensure their clinical utility in a variety of medical applications, from general research to clinical workflows. (frontiersin.org)
The accurate analysis of medical images accelerates the development and upgrading of intelligent algorithms that can be integrated into the software to enable easy-to-use clinical research. (frontiersin.org)
The time has come to ask if we have invented a science (psychiatry) that has little to do with reality, and to answer that, the creation of multicentric data bases is proposed, in which biological (not just brain based), social, personal, clinical, etc. variables are integrated, to finally obtain correlations that allow us a reclassification of brain pathology that would be useful to offer integral and personalized treatments. (bvsalud.org)
Generally, the complexity and severity of a patient's clinical condition should dictate the selection of appropriate imaging procedures or treatments. (bvsalud.org)

Imaging studies of major depressive disorder have reported structural and functional abnormalities in a variety of spatially diverse brain regions. (psychiatryonline.org)
While his main focus has been the study of posttraumatic stress disorder (PTSD) his studies have shown that the effects of psychological trauma are not limited to PTSD, and are often resulted in other debilitating disorders, beyond PTSD, including bipolar illness, generalized anxiety disorder (GAD), major depressive disorder (MDD), substance and alcohol abuse, borderline personality disorder, complicated grief, functional impairment and physical disorders. (wikipedia.org)
BACKGROUND: Multi-modal magnetic resonance imaging (MRI) measures are supposed to be able to capture different brain neurobiological aspects of major depressive disorder (MDD). (bvsalud.org)
A promising new treatment approach for major depressive disorder (MDD) targets the microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions affected in MDD. (researchgate.net)
Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group. (nesda.nl)
Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. (nesda.nl)

Zhenbing Liu [ 7 ] used a multiscale residual neural network to collect multiscale information on a series of image slices and to classify AD, mild cognitive impairment (MCI), and NC. (hindawi.com)
Individuals with BD showed functional differences in the right posterior cingulate cortex during resting-state experiments, the left amygdala during emotional experiments, including those using a mixed (positive/negative) valence manipulation, and the left superior and right inferior parietal lobules during cognitive experiments, while hyperactivating the left medial orbitofrontal cortex during cognitive experiments. (nature.com)
We are also interested in understanding brain changes associated with cognitive and physical maturation during healthy development, which we have examined in a large sample of healthy children and adolescents. (clinicbarcelona.org)
We participate in single and multi-center treatment trials testing non-pharmacological (cognitive behavioural therapy for psychosis) and pharmacological (omega-3 fatty acids, n-acetil cysteine) interventions for treating symptoms of psychosis and improving functional outcomes, preventing grey matter loss following first episode of psychosis, or preventing transition to psychosis in high risk individuals. (clinicbarcelona.org)
The proposed method provides a new perspective for the analysis of brain structure differences of self-esteem, which also has potential guiding significance in other researches involved brain cognitive activity and brain disease diagnosis. (researchsquare.com)
Brain network aims to study the interaction of various brain regions as a whole, which has an important role to have a deep understanding of brain structures and cognitive neural processes. (researchsquare.com)
Dr. Newhouse's research has focused on central nicotinic mechanisms in degenerative brain disorders and the role of nicotinic receptor systems in normal and disordered cognitive functioning in humans. (vumc.org)
Another major focus includes studying the interaction of estrogen and central cholinergic, catecholaminergic, and serotonergic systems in relation to cognitive and emotional aging in the elderly and novel pharmacologic-imaging methodologies. (vumc.org)
Anodal transcranial Direct Current Stimulation (tDCS) has been shown to be an effective non-invasive brain stimulation method for improving cognitive and motor functioning in patients with neurological deficits. (surrey.ac.uk)
Both gray matter atrophy and disruption of functional networks are important predictors for physical disability and cognitive impairment in multiple sclerosis (MS), yet their relationship is poorly understood. (utwente.nl)
The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide study of the effects of environmental influences on behavioral and brain development in adolescents. (colorado.edu)
The main objective of the study is to recruit and assess over eleven thousand 9-10-year-olds and follow them over the course of 10 years to characterize normative brain and cognitive development, the many factors that influence brain development, and the effects of those factors on mental health and other outcomes. (colorado.edu)
The colocalization of structural and functional MRI correspondents of visuospatial associative test performance within medial-temporal regions validates multimodal imaging in describing behaviorally relevant variability in the aging brain and suggests that the Placing Test has the potential for detecting early cognitive changes occurring in preclinical phases of Alzheimer's disease. (ox.ac.uk)
For example, within the cerebellum, a structural separation emerges between lobules that are functionally connected to distinct, mainly sensorimotor, cognitive and limbic regions of the cerebral cortex and subcortex. (nih.gov)
The fly model displays well defined cognitive impairments and structural brain defects and the mouse model, although having subtle behavioral defects, has robust electrophysiological phenotypes and provides a tool to do extensive biochemical analysis of select brain regions. (stanfordchildrens.org)

In an attempt to generate sensitive methods for diagnostic classification this research explores a complimentary, global approach that utilizes entropy and statistical complexity measures applied to multi-modal data to obtain global measures of brain function. (bactra.org)
Dr. Christin Sander's research focuses on multi-modal functional brain imaging with combined MRI (magnetic resonance imaging) and PET (positron emission tomography). (martinos.org)
Working with high-field magnetic resonance spectrometers, this Section develops novel NMR methods and applies them to the study of neurotransmission and neurometabolism, with significant opportunities available for multi-modal collaborative imaging using MRS, MRI, and PET. (nih.gov)

We use imaging techniques including functional and structural magnetic resonance imaging (MRI), electroencephalogram (EEG), and positron emission tomography (PET) to inspect brain changes in blood-oxygen level dependent function, white matter microstructure, electrical conductivity, glucose metabolism and receptor availability. (mssm.edu)
The primary methods used by investigators in this Branch are PET (positron emission tomography) and NMR (nuclear magnetic resonance). (nih.gov)
Funding from the HBHL Core Facilities Grant is essential, as it allows partial coverage of the cost of several service contracts that maintain the BIC's technological and methodological platforms, including the Magnetic Resonance Imaging (MRI) Unit, Preclinical MRI Unit, the Positron Emission Tomography Unit and the Radiochemistry Unit. (mcgill.ca)
Second-tier imaging with molecular methods, preferably with fluorodeoxyglucose positron emission tomography (FDG-PET) (or single-photon emission CT [SPECT] if PET is unavailable), can provide greater diagnostic specificity. (medscape.com)

We first extracted the brain morphometric measures, including the cortical volume (CV), cortical thickness (CT), and surface area (SA), for each subject from the structural images, and then detected the structural clusters showing significant between-group differences in each measure using the surface-based morphology (SBM) analysis. (bvsalud.org)
This functionally meaningful structural architecture emerges from the covariation of gray matter volume and cortical folding. (nih.gov)
These results suggest that the neurotrophic events at play during development, and possibly evolution, which dictate that the size and folding pattern of distant brain regions should vary together across subjects, might also play a role in functional cortical specialization. (nih.gov)
Graph neural fields natively allow the inclusion of important features of cortical anatomy and fast computations of observable quantities for comparison with multimodal empirical data. (ox.ac.uk)
The thalamus is involved in regulating several brain functions, including motor, sensory, and higher cortical functions, and acts as a gateway between cortical and subcortical areas 13 , 14 . (phoenixrising.me)

The brain structure imaging analysis of patients with AD and normal people (normal control, NC) has found that the gray matter volume of AD patients was significantly lower than that of normal people, and the gray matter in the hippocampus, temporal poles, and temporal islands also has significant shrinkage [ 1 ]. (hindawi.com)
For example, self-face recognition occurs in the right brain, and autobiographical memory is mainly related to the hippocampus, and self-reference is related to the medial prefrontal lobe [5]. (researchsquare.com)

Based on functional MRI and perfusion data, They found support for a model in which life stress interacts with the effect of serotonin transporter genotype on amygdala and hippocampal resting activation, two regions involved in depression and stress. (dericbownds.net)
Visual assessment of brain perfusion MRI scans in dementia: a pilot study. (lu.se)

An optimization module can fit a model to multimodal empirical data using an evolutionary algorithm. (sfb1315.de)

Existing methods based on brain morphometry and single-layer brain network cannot characterize the subtle structural differences related to self-esteem. (researchsquare.com)
First, we performed a voxel-based morphometry correlational analysis on structural magnetic resonance imaging (MRI) data from 144 healthy older adults with their scores on the Placing Test. (ox.ac.uk)

A complete and clear intracranial anatomical structure through hierarchical scanning using sMRI can be obtained, which is helpful to analyze the morphological structure of brain gray matter, white matter, and cerebrospinal fluid and to determine whether a disease or injury exists. (hindawi.com)

In the present study, the authors applied a novel multimodal meta-analytic approach to test the hypothesis that major depression exhibits spatially convergent structural and functional brain abnormalities. (psychiatryonline.org)

Wondering about the use for this purpose of a multimodality imaging approach, encompassing MRI, PET, EEG/ERPs and neuropsychological measures? (mssm.edu)

Our findings shed light on the life-course evolution of the functional connectome and serve as a normative reference for quantifying individual variation in patients with neurological and psychiatric disorders. (bvsalud.org)
We present elaborate quantitative evidence of how this framework can significantly advance our search for missing links in complex brain disorders. (deepai.org)
Our results provide new insight into the genetic architecture of the brain with relevance to complex neurological and psychiatric disorders, as well as brain development and aging. (biorxiv.org)
The study of sex differences in the human brain is of great interest, also and especially to identify mechanisms underlying behavioral differences or to explain the prevalence of some psychiatric and neurological disorders (Salminen et al. (springer.com)
The Douglas-Bell Canada Brain Bank (DBCBB) currently houses over 3,500 brains from people with diverse psychiatric and neurological disorders (including schizophrenia, major depression, bipolar disorder, Alzheimer's disease and substance disorders) through special partnerships with research consortia. (mcgill.ca)
As the DBCBB contains tissue from psychiatrically healthy individuals and from those affected with psychiatric and neurological disorders, it allows for unique discoveries on the human brain and human illnesses, but also for research conducted in animals to be translated to humans. (mcgill.ca)
Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders : Evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group. (nesda.nl)

Functional activation of the same regions-controlling for the effect of atrophy-occurred during successful performance of the same task. (ox.ac.uk)
Brain image reveals hippocampal atrophy, especially on the right side. (medscape.com)

The INM supports FAIR Data and Open Science and therefore provides data management, analysis and simulation software as well as data to the neuroscientific community (e.g. brain maps, DataLad, NEST Initiative, Helmholtz Metadata Collaboration - HMC, National Research Data Infrastructure - NFDI). (fz-juelich.de)
However, brain aging trajectories in SZ patients have not been well-documented using three-modal magnetic resonance imaging (MRI) data. (njit.edu)
In this study, 138 schizophrenia patients and 205 normal controls aged 20-60 were included and multimodal MRI data were acquired for each individual, including structural MRI, resting state-functional MRI and diffusion tensor imaging. (njit.edu)
The brain age of each participant was estimated by features extracted from multimodal MRI data using linear multiple regression. (njit.edu)
In this study, we aimed to investigate brain aging trajectories in SZ patients using multimodal MRI data and revealed an aberrant brain age trajectory in young schizophrenia patients, providing new insights into the pathophysiological mechanisms of schizophrenia. (njit.edu)
We conduct a comprehensive evaluation of the taxonomy using functional and structural magnetic resonance imaging (MRI) data across a spectrum of Alzheimer's disease phenotypes and show that self-supervised models reveal disorder-relevant brain regions and multimodal links without access to the labels during pre-training. (deepai.org)
Of minimal relevance if you're not in Ann Arbor or don't care about complex systems, information theory, quantitative measures of complexity, brain imaging, or summarizing ridiculously largge amounts of data. (bactra.org)
As a demonstration the BrainWeb Simulated Brain Database is used to simulate data based on a common model of neurodegeneration. (bactra.org)
BACKGROUND: Machine learning (ML) can distinguish cases with psychotic disorder from healthy controls based on magnetic resonance imaging (MRI) data, but it is not yet clear which MRI metrics are the most informative for case control ML, or how ML algorithms relate to the underlying biology. (maastrichtuniversity.nl)
Jason Stockmann, PhD, is broadly interested in magnetic resonance imaging hardware and acquisition methods for improving data quality for both structural and functional imaging. (martinos.org)
Here, using a data-driven, multimodal approach for studying brain structure across the lifespan ( N = 484, n = 260 females), we demonstrate that numerous structural networks, covering the entire brain, follow a functionally meaningful architecture. (nih.gov)
As an example application, we study a stochastic Wilson-Cowan graph neural field model on a high-resolution connectome graph constructed from diffusion tensor imaging (DTI) and structural MRI data. (ox.ac.uk)
In this work, we present two data analysis frameworks for biomarker detection on brain imaging with FC, 1) graph analysis of FC and 2) multimodal fusion analysis, to better understand the human brain. (unm.edu)
Measurement and analysis of structural and functional imaging data. (mpg.de)

Magnetic resonance imaging and magnetoencephalography (MEG) were performed in 102 MS patients and 42 healthy controls. (utwente.nl)

Coordinate-based meta-analysis identified spatially convergent structural (VBM) and functional (VBP) abnormalities in major depression. (psychiatryonline.org)
No shared structural abnormalities were found. (nature.com)
And finally, we utilized a multimodal fusion analysis framework, multi-set canonical correlation analysis + joint independent component analysis (mCCA+jICA) to link functional and structural abnormalities in BD and MDD. (unm.edu)

Within the framework of the European flagship project Human Brain Project, several divisions of the INM are involved in the development of a state-of-the-art research infrastructure for brain research. (fz-juelich.de)
The concomitant rich and flexible unsupervised deep learning framework captures complex multimodal relationships and provides predictive performance that meets or exceeds that of a more narrow supervised classification analysis. (deepai.org)
neurolib is a computational framework for whole-brain modeling written in Python. (sfb1315.de)
Graph theory provides a modality invariant framework to analyze patterns of gray matter morphology and functional coactivation. (utwente.nl)
Here we show how these two types of brain activity can be mechanistically linked within the framework of the baseline-shift mechanism for the generation of evoked responses. (researchgate.net)

AI combined with machine learning methods is applied to medical image processing to obtain biomarkers and to assist doctors in making correct diagnoses. (hindawi.com)
Most existing methods use ROI-based brain network analysis methods to study brain structure and functional connections related to self-esteem. (researchsquare.com)

Besides the morphological alterations, some authors suggested that the microstructural changes of the thalamus assessed by diffusion tensor imaging (DTI) could also be related to fatigue in the early stages of MS 23 . (phoenixrising.me)

In summary, via the two frameworks, our work has made several contributions to advance FC analysis, which improves our understanding of underlying brain function and structure, and our findings may be ultimately useful for the development of biomarkers of mental disease. (unm.edu)
Multimodal MRI studies of fatigue in NMOSD are needed to find more precise imaging biomarkers for fatigue. (phoenixrising.me)

We used a multimodal imaging appoach (i.e. functional and structural magnetic resonance imaging, electroencephalography) to obtain complementary information regarding PLP-associated neural changes. (sfb1158.de)

The goal of research at the Institute of Neuroscience and Medicine (INM) is the development of a realistic, three-dimensional model of the human brain based on brain structure, brain function and dysfunction, each of which can be altered and modulated on different time scales. (fz-juelich.de)
Then, mysteriously, he left the lush and easy life of complexity for the arid desolation of neuroscience, sustained in his wanderings in the wilderness by the ravens of NMR physics and brain imaging . (bactra.org)

Structural imaging, preferably with MRI when possible and with computed tomography (CT) when not, should be performed as a first-tier approach. (medscape.com)

We report critical inflection points in the non-linear growth trajectories of the whole-brain functional connectome, particularly peaking in the fourth decade of life. (bvsalud.org)

Herein we report on a pilot study involving twelve participants with ALS and nine age-matched healthy controls who underwent high-resolution resting state functional magnetic resonance imaging at an ultra-high field of 7 Tesla. (biorxiv.org)

Prior assessments of MRI and PET performance in brain tumor imaging have relied on the cross-validation of imaging findings with surgical sampling. (debuglies.com)

Using both sensory stimulation and a virtual phantom movement task we found evidence for different roles of functional maladaptive reorganization and for preserved organization depending on the input modality being used, i.e. sensory or motor inputs and the consideration of the presence of severity of PLP. (sfb1158.de)

These psychological processes have their own corresponding brain regions. (researchsquare.com)
In addition to these independent brain regions, the difference in self-esteem is also reflected in the brain network connection. (researchsquare.com)
The anatomical brain network mainly uses the region of interest (ROI) of the brain as the node, and the correlation between brain regions as edge [7-8]. (researchsquare.com)
These findings may have implications for determining promising target regions for disorder-specific neuromodulation interventions (e.g. transcranial magnetic stimulation or neurofeedback). (nature.com)
MEG functional networks were computed at the subject level based on the phase-lag index between time-series of regions in source-space. (utwente.nl)
These results suggest that neurotrophic events occur during development to dictate that the size and folding pattern of distant, functionally connected brain regions should vary together across subjects. (nih.gov)
T2w MRI is instrumental in assessing edema, while T1w MRI can highlight regions with a compromised blood-brain barrier due to gadolinium enhancement. (debuglies.com)
These tracers have the advantage of crossing the blood-brain barrier (BBB), allowing them to detect invasive non-enhancing tumor regions with greater sensitivity than MRI. (debuglies.com)
By assessing the temporal coherence of the hemodynamic activity among brain regions, FC is considered capable of characterizing the large-scale integrity of neural activity. (unm.edu)
In addition, the study identified 34 predictors that contributed to alcohol use by age 18, including being male, higher socioeconomic status, early dating, more externalizing behaviors, worse executive functioning, and thinner cortices, and less brain activation in diffusely distributed regions of the brain. (psychnews.org)

Oxidative stress and brain morphology in individuals with depression, anxiety and healthy controls. (nesda.nl)

Furthermore, we aim to continue to use a transdiagnostic approach to test specificity of our findings in relation to current psychiatric classifications, and to identify brain based markers of resilience towards mental disease. (clinicbarcelona.org)
Such findings raise questions as to how sensory and motor inputs alter phantom pain and brain structure-function, which deserve further investigation. (sfb1158.de)

Researchers found that undergraduates with different self-esteem grades have brain structural differences. (researchsquare.com)
Therefore, in this study, we focus on exploring the differences between brain networks of undergraduates with different levels of self-esteem. (researchsquare.com)
This argues for a multidimensional view of sex brain differences and suggests that the issue should be approached with more complex models than previously thought. (springer.com)

Brain function is typically measured using task-based functional MRI (tfMRI) in which subjects perform tasks or experience sensory stimuli, and uses imaging sensitive to local changes in blood oxygenation and flow caused by brain activity in grey matter. (biorxiv.org)

Brain structure and allelic associations in Alzheimer's disease CNS Neurosci Ther. (usc.edu)

The Genetic Architecture of Multimodal Human Brain Age bioRxiv. (usc.edu)
Genetic architecture of subcortical brain structures in 38,851 individuals. (nesda.nl)

We carried out genome-wide association studies of 3,144 distinct functional and structural brain imaging derived phenotypes in UK Biobank (discovery dataset 8,428 subjects). (biorxiv.org)

The taxonomy forms a family of decoder-free models with reduced computational complexity and a propensity to capture multi-scale relationships between local and global representations of the multimodal inputs. (deepai.org)

Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)

Understanding neurocognitive factors that predate substance use initiation is crucial to specifying the consequences of substance use on brain development, as well as identifying at-risk youths and potential targets of preventive efforts. (psychnews.org)
Impaired brain metabolism and neurocognitive function in childhood leukemia survivors despite complete hormone supplementation in adulthood. (lu.se)

The causal role of neuroplastic alterations in brain circuits and interacting peripheral factors in shaping the experience of phantom limb pain (PLP) is not yet well understood. (sfb1158.de)
Thirdly, two functional measures, FNC and fractional amplitude of low frequency fluctuations (fALFF), were spatially overlaid to compare the FC and spatial alterations in SZ. (unm.edu)

Here, we present a Heterogeneous Graph neural network for Multimodal neu. (deepai.org)

To solve this issue, we proposed multiple anatomical brain network method based on multi-resolution region of interest (ROI) template to study the structural connections of self-esteem. (researchsquare.com)
The multiple anatomical brain network consist of ROI features and hierarchal brain network features that are extracted from structural MRI. (researchsquare.com)
The definition of ROI is a key step in anatomical brain network analysis. (researchsquare.com)

The functional connectome of the human brain represents the fundamental network architecture of functional interdependence in brain activity, but its normative growth trajectory across the life course remains unknown. (bvsalud.org)
They thus appear particularly suitable for modelling whole-brain activity at mesoscopic scales, and opening new potential avenues for connectome-graph-based investigations of structure-function relationships. (ox.ac.uk)

This article delves into the critical role of imaging in brain tumor management, explores the shortcomings of conventional MRI, and introduces an innovative multimodal approach to address these limitations. (debuglies.com)
Conventional MRI is a cornerstone in brain tumor patient care. (debuglies.com)
However, despite their widespread use, a comprehensive evaluation of the overall performance of amino acid PET tracers and conventional MRI for detecting the entire brain tumor burden remains elusive. (debuglies.com)
Surgical sampling cannot offer comparisons across the entire brain, leaving us in the dark about the performance of MRI and PET in detecting the entire tumor burden. (debuglies.com)

However, the topological organization of large-scale functional brain networks remains unexplored in endurance runners. (bvsalud.org)
In MS patients, we found a more regular network organization for structural covariance networks and for functional networks in the theta band, whereas we found a more random network organization for functional networks in the alpha2 band. (utwente.nl)
Here, by investigating intersubject variation in brain structure across a large number of individuals, we reveal modes of structural variation that map onto fine-grained functional organization across the entire brain, and specifically in the cerebellum, visual areas, and default-mode network. (nih.gov)
In Proceedings of the 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM). (mpg.de)
Intrinsic brain organization underlying impulsivity. (mpg.de)

Axial, T2-weighted magnetic resonance imaging (MRI) scan reveals atrophic changes within bilateral temporal lobes with prominence of the sylvian fissures. (medscape.com)

Coronal, T1-weighted magnetic resonance imaging (MRI) scan in a patient with moderate Alzheimer disease. (medscape.com)
Brain, coronal view. (medscape.com)

Annette Sterr is a neuropsychologist with an interest in understanding the link between brain function and behaviour in health and disease. (surrey.ac.uk)

Coarse labels do not capture the long-tailed spectrum of brain disorder phenotypes, which leads to a loss of generalizability of the model that makes them less useful in diagnostic settings. (deepai.org)

Hamid Sabet, is Assistant Professor of Radiology at Harvard Medical School and a Cyclotron/Medical Physicist at the Division of Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital. (martinos.org)

Journal of Cardiovascular Magnetic Resonance. (lu.se)

In this paper, a multimodal diagnosis method for AD based on three-dimensional shufflenet (3DShuffleNet) and principal component analysis network (PCANet) is proposed. (hindawi.com)
Practice parameters for diagnosis and evaluation of dementia, as published by the American Academy of Neurology (AAN), consider structural brain imaging to be optimal. (medscape.com)
Disclaimer: The ACR Committee on Appropriateness Criteria and its expert panels have developed criteria for determining appropriate imaging examinations for diagnosis and treatment of specified medical condition(s). (bvsalud.org)

The Joint Lab 'Supercomputing and Modeling for the Human Brain" (SMHB) with the Jülich Supercomputing Center pursues the goal of enabling the analysis and simulation of the brain through innovative computing. (fz-juelich.de)
Human Brain Mapping. (kcl.ac.uk)
Human brain mapping , 35 (12), 5946-5961. (utwente.nl)
Evoked responses and ongoing oscillations represent two major electrophysiological phenomena in the human brain yet the link between them remains rather obscure. (researchgate.net)
Interested in learning about the human brain and its basic functions inclusive of learning and memory (including reinforcement learning and memory reconsolidation), decision-making, self-control/regulation and self-awareness/insight? (mssm.edu)
Despite a long tradition of studying sexual dimorphism in the human brain, to our knowledge only one study has addressed the influence of sex on HC. (springer.com)
Human brain structure topography is thought to be related in part to functional specialization. (nih.gov)
SIGNIFICANCE STATEMENT Questions about the relationship between structure and function in the human brain have engaged neuroscientists for centuries in a debate that continues to this day. (nih.gov)
Tools from the field of graph signal processing, in particular the graph Laplacian operator, have recently been successfully applied to the investigation of structure-function relationships in the human brain. (ox.ac.uk)

The correlation between the brain age gap and chronological age in SZ patients was best fitted by a positive quadratic curve with a peak chronological age of 47.33 years. (njit.edu)

Having established the first fine-grained, lifespan-spanning suite of system-level brain atlases, we generate person-specific parcellation maps and further show distinct maturation timelines for functional segregation within different subsystems. (bvsalud.org)

These two sections include a strong methodological orientation, with state-of-the-art facilities to develop, evaluate, and then apply new radiotracers for in vivo imaging. (nih.gov)

Based on a logistic regression model, we performed a classification analysis by selecting these structural and functional cluster-wise measures as features to distinguish the MDD patients from the HC. (bvsalud.org)
Candidate objective measures may be based on minimally invasive imaging technologies, electrophysiological recordings, integration of multiparametric imaging and electrophysiology approaches, or their integration with other markers (e.g. , immune factors, genomic markers, physiological factors) through multiscale modeling or machine learning analysis. (nih.gov)
neurolib can load structural and functional datasets, set up a whole-brain model, manage its parameters, simulate it, and organize its outputs for later analysis. (sfb1315.de)
However, the image analysis process usually involves multiple modality-specific software and relies on rigorous manual operations, which is time-consuming and potentially low reproducible. (frontiersin.org)
Numerous choices of medical image analysis tools integrating advanced algorithms are available. (frontiersin.org)
Diagnostic test accuracy of artificial intelligence-based imaging for lung cancer screening: A systematic review and meta-analysis. (cdc.gov)

Accelerated brain aging had been widely reported in patients with schizophrenia (SZ). (njit.edu)
In the normal controls, brain age matched chronological age well for both the youth and middle age groups, but this was not the case for schizophrenia patients. (njit.edu)
More importantly, schizophrenia patients exhibited increased brain age in the youth group but not in the middle age group. (njit.edu)

neurolib is designed to be extendable such that custom neural mass models can be implemented easily, offering a versatile platform for computational neuroscientists for prototyping models, managing large numerical experiments, studying the structure-function relationship of brain networks, and for performing in-silico optimization of whole-brain models. (sfb1315.de)
However, the impact of ovarian hormone fluctuations on brain structure earlier in life is less understood. (researchgate.net)
The genetic basis of brain structure and function is largely unknown. (biorxiv.org)
Brain structure and function are known to vary between individuals in the human population and can be measured non-invasively using Magnetic Resonance Imaging (MRI). (biorxiv.org)
We explored the relationship between performance on a visuospatial associative memory task (the Placing Test) and brain structure and function in cognitively healthy older adults. (ox.ac.uk)

We will also use virtual and augmented reality applications in addition to electromyographic recordings from the residual limb to model the dif ferential role of somatosensory, motor and visual inputs from the phantom for brain changes and PLP. (sfb1158.de)

Anatomy36

Organisms1

Diseases18

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment65

Psychiatry and Psychology90

Phenomena and Processes41

Disciplines and Occupations5

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture2

Humanities2

Information Science16

Health Care17

FMRI27

Connectivity26

Modalities10

Spectroscopy5

Neuroimaging20

Clinical16

Major depressi6

Cognitive15

Multi-modal3

Positron4

Cortical5

Hippocampus2

Perfusion2

Empirical data1

Morphometry2

SMRI1

Meta-analytic1

Neuropsychological1

Disorders7

Atrophy2

Data14

Magnetoencephalography1

Abnormalities3

Framework5

Methods2

Diffusion1

Biomarkers2

Electroencephalography1

Neuroscience2

Computed tomography1

Trajectories1

State functional1

Assessments1

Severity1

Regions10

Morphology1

Findings2

Differences3

Sensory1

Alzheimer's1

Genetic Architecture2

Dataset1

Complexity1

Dysfunction1

Neurocognitive2

Alterations2

Neural network1

Anatomical3

Connectome2

Tumor4

Organization5

Temporal1

Coronal2

Disease1

Phenotypes1

Radiology Department1

Cardiovascular1

Diagnosis3

Human Brain9

Correlation1

Fine-grained1

Methodological1

Analysis6

Schizophrenia3

Structure5

Inputs1