Strong genetic determination. Medical search. Frequent questions

A previously reported 15-loci STR multiplex was evaluated. (ojp.gov)
A novel 13-loci STR multiplex was developed and optimized for cannabis sativa identification (3500 Genetic analyzer), according to ISFG and SWGDAM recommendations, using primer and multiplex STR design software, along with a gradient PCR approach for optimal annealing temperature determination. (ojp.gov)
As a proof of concept, a custom panel for MPS was designed to interrogate 12 cannabis-specific STR loci by sequence rather than by size. (ojp.gov)
The study resulted in a preliminary investigation of sequence variation for 12 autosomal STR loci in 16 cannabis samples. (ojp.gov)
We offer reliable and speedy STR-based DNA profiling for human cell line testing which includes analysis of 15 genetic loci or markers vs. the 8 recommended by ATCC & 1 sex determination locus/marker with high resolution using ABI identifiler kit & GeneMapper software. (biosyn.com)
Zeye MMJ, Li J, Ouedraogo SY, Zha L, Simpore J, Jifeng C. Population data and genetic structure analysis based on 29 Y-STR loci among the ethnolinguistic groups in Burkina Faso. (scirp.org)

The alleles of STR locus change according to the number of repeats of the given sequence motive. (genomia.cz)
From an analysis of mutants able to grow on glutamate we have identified a genetic locus that when mutated elevates the expression of the GltII glutamate/aspartate transport system. (microbiologyresearch.org)
Data from the analysis of mutants that are impaired in this transport activity are consistent with the presence of the structural gene for the transport system at the same genetic locus. (microbiologyresearch.org)
Genetic studies of the phs locus in Escherichia coli, a mutation causing pleiotropic lesions in metabolism and pH homeostasis. (microbiologyresearch.org)

The determination of genetic profile means determination of a set of genetic markers that are characteristic and unmistakable for the given individual (such as, for example, fingerprints of people). (genomia.cz)
These sequences, also called microsatellites, are a class of genetic markers consisting of tandem sequence repeats with a size of two to seven base pairs. (genomia.cz)
Due to high level of polymorphism (informativity) and Mendelian inheritance, the microsattelites became suitable genetic markers for the study of diversity, parentage tests and the genetic identity. (genomia.cz)
A cheaper strategy is to employ a subset of markers that can efficiently recapitulate the population genetic structure inferred by the whole genome data. (nature.com)
2000 ). Traditionally, upon the advent of Polymerase Chain Reaction (PCR) technology, genetic variation within wild populations used to be determined either employing a handful of neutral microsatellite markers or assessing mitochondrial DNA sequences (Chapman et al. (nature.com)
2009 ). With the advancement in next-generation sequencing (NGS) techniques several thousand to millions of markers across the genome have become available for population genetic analysis, even for non-model organisms (Khan and Tyagi 2021 ). (nature.com)
Here we provide an overview of genetic drug response markers for affective disorder. (eurekaselect.com)
Central in review is the question if individual therapeutic outcome for a given treatment can be predicted using genetic markers? (eurekaselect.com)
Analysis of additional markers provided evidence supporting widespread genetic co-susceptibility for spherical and astigmatic refractive errors. (ox.ac.uk)
To assess if the behavioral difference between the family and kenneled dogs could be due to genetic divergence of these two populations and/or to lower genetic diversity of the kenneled dogs, we analyzed their genetic structure using 11 microsatellite markers. (frontiersin.org)

STR alleles are determined by means of multiplex polymerase chain reaction (multiplex PCR). (genomia.cz)

Thus, the behavior difference between the groups more likely reflects a G × E interaction, that is, the influence of specific genetic variants manifesting under specific environmental conditions (kennel life). (frontiersin.org)
In paper 2, I studied the association between LRIG1 genetic variants and BMI, T2D and lipid biomarkers. (lu.se)
In addition, effects of novel LRIG1 genetic variants on BMI and T2D might enrich our understanding of lipid metabolism and T2D and thus warrant further investigations. (lu.se)

Accurately inferring population genetic structure requires whole-genome data across the geographical range of the species, which can be resource-intensive. (nature.com)
Assessing the population genetic structure of wild species is important for their management (Wultsch et al. (nature.com)
Scientists now say that species like this one thrived in the world's oceans millions of years ago after evolving genetic sex determination and live-born young. (harvard.edu)
Having drawn this link in three lineages of extinct marine reptiles - mosasaurs, sauropterygians, and ichthyosaurs - the scientists say that genetic, or chromosomal, sex determination may have played a surprisingly strong role in adaptive radiations and the colonization of the world's oceans by a diverse array of species. (harvard.edu)
Organ, Janes, and colleagues show that evolution of live birth in a species depends on the prior evolution of genetic sex determination. (harvard.edu)
Because the fossilized remains of preg-nant mosasaurs, sauropterygians, and ichthyosaurs show that these species gave birth to live young, they must also have employed genetic sex determination, a point on which the fossil record is silent. (harvard.edu)
Experts on different groups will guide you through the secrets of species determination. (lu.se)
Previous investigations in this species showed a strong influence of temperature on sex determination with an underlying genetic basis. (uni-goettingen.de)
Examination of the Z and W chromosome-specific CDH (chromo-helicase binding protein) gene allows the determination of the sex of a number of bird species, including falcons, common eiders and turkey. (nrdpfc.ca)
Competing causes of mortali- or all of the animal species tested genetic variation, health status, life ty may prevent the development of experimentally. (who.int)

These estimates provide new insight into the mechanisms that govern mate choice in humans and warrant the search for the genetic causes of choice of mate height. (biomedcentral.com)
Determining sex with genetic mechanisms allowed marine reptiles to give live birth, in the water, as opposed to laying eggs on a nesting beach," says Chris Organ , a research fellow in Harvard's Department of Organismic and Evolutionary Biology . (harvard.edu)
The proposed research project will involve the elucidation of antibacterial resistance mechanisms, determination of gene essentiality, and generation of the genetic tools to better evaluate A. baumannii . (fems-microbiology.org)

The use of state-of-the-art genetic approaches (including transcriptomics, phenomics, epigenomics, whole genome association studies, next generation sequ encing, exome sequencing, & systems biology) to identify and validate (including in vitro models, animal models, & human samples) viral and host genetic factors which influence the pathophysiology of HAND are encouraged. (nih.gov)

Genetic disorder Genetic epidemiology Family cancer syndrome Blue Fugates Butcher, J., S. Mineka, and J. Hooley. (wikipedia.org)
These findings support the social push perspective and make important contributions to the social demography and genetic epidemiology of smoking as well as to the gene-environment interaction literatures. (dukeupress.edu)

The study of biomarkers of genetic susceptibility in the context of workplace exposures can provide information about gene-environment interactions. (cdc.gov)

To determine the genetic profile, tandem repetitive sequences (STR) are used. (genomia.cz)
With only a limited number of samples, including 11 more from this dive, Cheryl hopes to determine the genetic diversity and be able to match it to natural sites surrounding the wreck. (noaa.gov)

On the other hand, dogs bred and kept solely for breeding or research purposes ("kenneled dogs") are kept and handled under standardized conditions, and are usually of the same breed, thus the effects of environmental and breed-specific genetic variability on their individual behavioral variability is small. (frontiersin.org)

Short tandem repeat (STR) analysis is carried out for purposes of individual identification, assignment of population of origin and parentage determination. (nrdpfc.ca)

This study examined the forensic genetic issues associated with the identification and origin determination of Cannabis Sativa. (ojp.gov)
Evaluation results indicated that this STR system is not suitable for forensic identification due to identified issues. (ojp.gov)
Identification of genetic structure within wildlife populations have implications in their conservation and management. (nature.com)
In this chapter we will present the usefulness of genetic DNA testing of skeletonized remains for human identification, by using automate DNA extraction from three different human bone types: tooth, femur and petrous pyramid. (intechopen.com)

The new frontiers of genetic engineering and advanced biotechnologies, Emergence of new paradigms. (scirp.org)

Furthermore, because height is a highly polygenic trait [ 11 ], with hundreds of genes of small effect scattered across the genome contributing to its variation, it is possible that the build-up of directional linkage disequilibrium (LD) that arises from assortative mating impacts not only on the genetic architecture of height but also on that of many other complex traits. (biomedcentral.com)
An interesting variation on this is seen in certain crustaceans, in which sex determination is influenced not only by sex chromosomes but also by the presence or absence of intracellular symbionts such as the bacterium Wolbachia . (andrewgray.com)
Regarding the high response to selection and realized heritability the action of few major genes causing the bulk of additive variation and minor genes causing the remaining additive variance seem to be responsible for expression of temperature sex determination in Nile Tilapia. (uni-goettingen.de)

As a genetic specialist, Cheryl is looking at the genetic diversity of the Lophelia throughout the Gulf. (noaa.gov)
We found no significant difference between the populations in their genetic diversity (i.e., heterozygosity, level of inbreeding), nor any evidence that the family and kenneled populations originated from different genetic pools. (frontiersin.org)

The National Institute of Mental Health (NIMH) and The National Institute of Neurological Disorders and Stroke (NINDS) solicit research grant applications to supp ort studies focused on viral and host genetic factors involved in HIV-1 Associated Neurocognitive Disorders (HAND) in the setting of highly active anti-retroviral therapy (HAART). (nih.gov)
Height is a model quantitative trait that is determined by the interplay of large numbers of genetic and environmental factors. (biomedcentral.com)
Importantly, we then show that genetic factors for smoking desistance increase in importance following restrictive legislation on smoking behaviors that occurred in the early and mid-1970s. (dukeupress.edu)
however, little is known about the extent to which these relationships are genetic or determined by environmental factors. (lu.se)
Biochemical studies suggest that in one case this transcription factors to implement particular genetic programs. (lu.se)
Major technological advances in the last few years have increased our knowledge of the role that genetics has in occupational diseases and our understanding of genetic components and the interaction between genetics and environmental factors. (cdc.gov)
The use of genetic information, along with all of the other factors that contribute to occupational morbidity and mortality, will play an increasing role in preventing occupational disease. (cdc.gov)

For annual plants, such as Arabidopsis thaliana , proper determination of the flowering time is critical for plant reproductive success because a switch from vegetative to reproductive development is irreversible. (biomedcentral.com)

Genetic analysis of the glutamate permease in Eschericha coli K-12. (microbiologyresearch.org)
The determination of when to request RFLP analysis during a false-positive culture investigation rests on whether there was a preexisting suspicion of a problem. (cdc.gov)

Evaluation of genetic damage can provide information about exposure or effect of exposure. (cdc.gov)

Your specific role will be to analyse single cell RNAseq and ATACseq data to reconstruct the genetic program behind lineage specification and sex specific differentiation. (sfbi.fr)
Hematopoietic stem cell lineage choices are decided by genetic networks that are turned ON/OFF in a switch-like manner. (lu.se)
We develop a computational model for the hematopoietic erythroid-myeloid lineage decision, which is determined by a genetic switch involving the genes PU.1 and GATA-1. (lu.se)
Dynamical models based upon known interactions between these master genes, such as mutual antagonism and autoregulation, fail to make the system bistable, a desired feature for robust lineage determination. (lu.se)
The genetic switch, which handles the erythroid-myeloid lineage decision, is an example of a network that implements both a primed and a committed state by regulating cooperativity through recruitment of cofactors. (lu.se)

Although the etiology and pathophysiology is widely unknown, family-, twin- and adoption studies argue for a strong genetic determination of these disorders. (eurekaselect.com)

So while it'd be foolish to argue that hard work and determination and coaching don't help to make great players great, it'd be just as foolish to ignore the genetic evidence in front of us. (freakonomics.com)

While it is clear that both genetic and developmental effects play some role in the emergence and manifestation of these behaviors, we still do not fully understand the effect of the human social environment on dog behavior. (frontiersin.org)

These 49 SNPs were sufficient to recapitulate the population genetic structure obtained from the whole genome data. (nature.com)

Furthermore, we identified a subpopulation of secretory precursors juxtaposed to presumptive neuroepithelial bodies (NEBs), distinguished by their strong Scgb3a2 and uroplakin 3a (Upk3a) signals and reduced Ccsp (Scgb1a1) expression. (harvard.edu)

Assortative mating increases both the genetic and phenotypic variance compared to that observed in a random mating population [ 1 ] and plays a crucial role in shaping the genome structure of the population (i.e. how alleles are assorted) through increased coupling of alleles with positive or negative effects on the trait. (biomedcentral.com)
Along with raising public health concerns, the frustratingly slow progress presents a puzzle about population health and longevity: despite widespread acceptance of the harm of smoking, high cigarette prices, social disapproval, restrictions on places to light up, and strong desires among users to quit, nearly one-fifth of the U.S. adult population still smokes (Thorne et al. (dukeupress.edu)
In the transplant population, antigen assays or PCR is used (sometimes in conjunction with cytopathology) for diagnosis and treatment determinations. (medscape.com)

According to a study by the London School of Economics and Political Science, IQ is one of the strongest predictors of success in life. (greenpois0n.com)
We strive to ignite a spark of hope that fuels their resilience and empowers them to face life with confidence and determination. (elliesarmy.org)
You can accomplish this by creating maps for your team so everyone-receptionists, technicians, kennel personnel, and veterinarians-knows how a visit will progress and what a pet could need depending on its lifestyle, life stage, and genetic risk. (dvm360.com)
Bryophytes have a life-cycle dominated by the haploid generation, in strong contrast to other land plants which are dominated by the diploid generation. (lu.se)
You will examine the different stages of this life cycle and get insights in the genetic consequences of such a life cycle. (lu.se)
A recipient of multiple joint replacements due to a genetic condition, who sees every replacement as just another bump in the road in a fulfilling life. (newswire.ca)

Day length has a strong influence on flowering time and for some plants, termed long-day (LD) plants, exceeding of critical day length is necessary for the transition to flowering. (biomedcentral.com)
However, once we condition on having positive financial wealth, we find that nurture has a much stronger influence on risk-taking by children, and the evidence of a relationship between stock-holding of biological parents and their adoptive children becomes weaker. (lu.se)

Thus, the results obtained showed that it is realistic to obtain a male proportion exceeding 95%, which is necessary to effectively avoid stunting, by means of selection for temperature dependent sex determination.In contrast, prolongation of temperature treatment to 30 days was not able to induce temperature sex reversal in crosses and meiotic gynogenetic offspring of genetic female homozygous isogenic lines. (uni-goettingen.de)

The aim here is to introduce new brain activity that will cumulatively erode "the determination to believe" and the commitment to create. (sott.net)

Millogo M, Soubeiga ST, Bazie BVJT, Zohoncon TM, Ouattara AK, Yonli AT, Simpore J. Disputed paternity presumption in Burkina Faso: determination of the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays. (scirp.org)

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. (ox.ac.uk)

I fully recognize that I won the genetic lottery by having my Dad as half of my genetic make up. (soapqueen.com)
At Mackenzie Health we recognize the personal strength and determination required on the journey back to good health. (newswire.ca)

In fact, they are currently encouraging couples to commit the ultimate discrimination by offering a " special sale " - a discounted fee of $14,880 for cycles with PGD gender determinations made until June 30, 2018. (womenofgrace.com)

Intracellular symbionts such as Wolbachia gain an obvious genetic advantage by converting males into females, because the symbionts are transmitted primarily down the maternal line (from mother to offspring). (andrewgray.com)

A high response to selection and a realised heritability of 0.69, clearly demonstrated that temperature sex determination has a highly heritable genetic background. (uni-goettingen.de)

Although the panel was not fully optimized and only a small number of samples were evaluated, this study demonstrated that more informative STR typing can be performed on a MS platform. (ojp.gov)
A PhD position is available in the laboratory of Prof. Serge Nef at the University of Geneva Medical School to study, at the single cell level, the process of gonadal sex determination in mammals. (sfbi.fr)

But there's also a strong counter-argument in the NFL to be made for raw talent. (freakonomics.com)
Determination on requests for reasonable accommodation are made on a case-by-case basis. (themuse.com)

For example, people with high IQs often have strong academic backgrounds, which leads to successful careers in professions like medicine or law. (greenpois0n.com)

Here we identify expression of the secretoglobin Scgb3a2 and Notch activation as early events in a program of secretory cell fate determination in developing murine airways. (harvard.edu)

Hard work, determination, and creativity are all essential ingredients for any successful person, no matter what their IQ is. (greenpois0n.com)
RICHMOND HILL and VAUGHAN, ON , May 30, 2016 /CNW/ - Every day, the healthcare team at Mackenzie Health is inspired by the courage and determination shown by patients as they work to regain their health following an injury or illness. (newswire.ca)
Every day our staff and physicians see the courage and determination of patients who work hard to recover from illness or injury. (newswire.ca)

Moreover, exploring the genetic background of their higher resilience could also help to better understand the genetics behind stress- and fear-related behaviors. (frontiersin.org)

When patients who are clustered by the two PCR tests are thought to be involved in the same chain of recent transmission and previous contact investigations established known epidemiologic links between them, chances are very good that RFLP results will confirm the genetic identity of the isolates. (cdc.gov)

Specifically, the role of genetic information in occupational disease is discussed in Chapter 2, followed in Chapter 3 by a presentation of how genetics is incorporated into occupational health research. (cdc.gov)
Health records as a source of genetic information are discussed in Chapter 4. (cdc.gov)
The report continues in Chapter 5 with a focus on genetic monitoring, followed in Chapter 6 by a theoretical discussion of genetic screening. (cdc.gov)

while the strongest form of scientific evidence about the effectiveness and/or harmfulness of conversion therapies is not available, there is still good reason to think that conversion therapies are often ineffective and have the potential to be harmful. (psephizo.com)
If any genotyping test shows that two isolates have different genotypes, this provides strong evidence that the two isolates are genetically distinct. (cdc.gov)

Due to the fact that no correlated response to selection was observed in the control groups, it is argued that temperature sex determination and genetic sex determination can be described as two distinct traits not being genetically correlated.The results obtained showed that selecting for temperature dependent sex ratios is a feasible approach to redundantise hormone feeding to sexually undifferentiated fry. (uni-goettingen.de)

Being a "strong feminist" has nothing to do with flouting God's will for our lives and making other people suffer in the process - such as the millions of tiny human lives who are being flushed down the drain in fertility centers for no other reason than because they're the "wrong" sex. (womenofgrace.com)

Family aggregation may arise because of genetic or environmental similarities. (wikipedia.org)

Here we provide an estimate of the genetic contribution to height choice in mates in 13,068 genotyped couples. (biomedcentral.com)

Determination of causal relationships between phenotypes related to positive energy balance and disease outcomes, as well as elucidation of the nature of these relationships, may help inform public health intervention policies. (lu.se)
However, the use of genetic information in occupational safety and health research and practice presents both promise and concerns [McCanlies et al. (cdc.gov)
In addition, ethical issues specific to health records and genetic testing are discussed in Chapters 4 and 6, respectively. (cdc.gov)

The results clearly indicated selection for temperature dependent sex determination is possible. (uni-goettingen.de)

Proficiency in Microsoft Office in addition to strong written, verbal and listening skills. (themuse.com)

To distinguish between genetic and environmental determinants of risky financial behavior, the literature has focused on twins studies.4 Cesarini et al. (lu.se)

Ellie Levy was born with cystic fibrosis (CF), a terminal genetic lung disease. (elliesarmy.org)
Ellie battled her disease with bravery, determination, wisdom, and an amazing sense of humor. (elliesarmy.org)
Role of Genetic Information in Occupational Disease: The role of genetic information in occupational disease is being explored. (cdc.gov)
One major emphasis of genetic research in occupational disease has been in the area of response variability. (cdc.gov)

My Dad, Dr. Richard Faiola, of Olympia, WA (yes, he is the best general practice Doctor in Olympia, WA ) taught me (along with strong support from my awesome mom) everything I know about determination, being tenacious, willful curiosity and being a leader with integrity within my community. (soapqueen.com)

Anatomy10

Organisms8

Diseases2

Chemicals and Drugs74

Analytical, Diagnostic and Therapeutic Techniques and Equipment93

Psychiatry and Psychology1

Phenomena and Processes60

Disciplines and Occupations10

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture7

Information Science7

Health Care17

Loci6

Locus4

Markers10

Polymerase chain re1

Variants3

Species10

Mechanisms3

Transcriptomics1

Epidemiology2

Susceptibility1

Determine the genetic2

Breed-specific genetic1

Parentage1

Identification4

Paradigms1

Variation3

Diversity2

Factors7

Irreversible1

Analysis2

Evaluation1

Lineage5

Disorders1

Argue1

Emergence1

Data1

Signals1

Population3

Life6

Influence2

Contrast1

Commitment1

Biological1

Genome1

Recognize2

Gender1

Males1

Heritability1

Study2

Made2

High1

Expression1

Work3

Background1

Identity1

Chapter3

Evidence2

Distinct1

Human1

Family1

Genotyped couples1

Health3

Results1

Addition1

Studies1

Disease4

Practice1