Stromal adipose tissue white. Medical search. Frequent questions

3D cell culturing by magnetic levitation method (MLM) is the application of growing 3D tissue by inducing cells treated with magnetic nanoparticle assemblies in spatially varying magnetic fields, using neodymium magnetic drivers and promoting cell to cell interactions by levitating the cells up to the air/liquid interface of a standard petri dish. (wikipedia.org)
This often compromises experiments in basic life science, leads to misleading drug-screening results on efficacy and toxicity, and produces cells that may lack the characteristics needed for developing tissue regeneration therapies. (wikipedia.org)
The unique ability to manipulate cells and shape tissue magnetically offers new possibilities for controlled co-culturing and invasion assays. (wikipedia.org)
We show that depletion of CAVIN1 in prostate stromal cells markedly reduces their lipid droplet accumulation and increases inflammation. (aacrjournals.org)
Stromal cells lacking CAVIN1 enhance prostate cancer cell migration and invasion. (aacrjournals.org)
Our data support the concept that stromal cells contribute to prostate cancer aggressiveness by modulating lipid content and inflammation in the tumor microenvironment. (aacrjournals.org)
2012). Human periprostatic white adipose tissue is rich in stromal progenitor cells and a potential source of prostate tumor stroma . (up.pt)
Adipose stromal cells play a key role in releasing estrogens and pro-inflammatory cytokines, while circulating adipose stromal cells (CASCs) home to tumor sites and promote angiogenesis and vascularization. (ku.edu)
These findings suggest that evaluation of circulating adipose stromal cells could have value as a response biomarker in weight loss intervention trials of both high risk women and breast cancer survivors. (ku.edu)
5 , - , 9 This loose connective tissue is composed of extracellular matrix and various types of cells: fat cells-named adipocytes, and the non-fat cells of the stromal vascular fraction that contains preadipocytes, capillary endothelial cells, infiltrating leucocytes and multipotent stem cells. (bmj.com)
The Adipoq-Cre exhibited no observable recombination in any other tissues examined, whereas both aP2-Cre lines resulted in recombination in endothelial cells of the heart and nonendothelial, nonmyocyte cells in the skeletal muscle. (diabetesjournals.org)
Adipose cells organized in small clusters under the reticular dermis closely interact with hair follicular cells and regulate the hair cycle. (jcadonline.com)
Adipose tissue is a loose connective tissue composed of cells supported by an intracellular matrix as well as by vascular, lymphatic, and neural networks. (jcadonline.com)
iXCells Biotechnologies provides SVF from human subcutaneous white fat tissue by enzymatic isolation and cryopreserved at P0, with ≥ 1.0 million cells/vial (Normal) or 0.5 million cells/vial (Diseased). (ixcellsbiotech.com)
Human Adipose-derived Stem/Stromal Cells (ASCs) have been widely used in stem cell and obesity research, as well as clinical applications including cell-based therapies, tissue engineering and reconstruction. (edu.au)
Compared with mesenchymal stem cells (MSCs) derived from other tissues such as umbilical cord and bone marrow, isolation of ASCs from human white adipose tissue (WAT) has great advantages due to its rich tissue source and simple surgical procedure. (edu.au)
If a tissue is infected, immune cells in the draining lymph node become activated and proliferate. (nature.com)
Here authors show that the rapid postnatal expansion of lymph nodes is governed by CD34 + stromal cells and fibroblastic reticular stromal cell progenitors, distinguished by intrinsic, microbiome-independent core epigenetic blueprints. (nature.com)
Unconventional T cells of different lineages migrate from peripheral tissues to draining lymph nodes, where they operate as a connected functional unit to shape tissue-specific responses. (nature.com)
The first chapter discusses the impact of type 2 diabetes (T2D) on adipose tissue mast cells while the second chapter focuses on the population dynamics and phenotypical changes of neutrophils, eosinophils, plasmacytoid dendritic cells, conventional dendritic cells, and mast cells in colorectal cancer. (ugr.es)
While adipocytes and macrophages were traditionally considered the primary contributors to adipose tissue expansion, recent research highlights the important role of mast cells in this process. (ugr.es)
Mast cells, which release various proangiogenic factors, play a pivotal role in angiogenesis and glucose-dependent adipogenesis, contributing to metabolically healthy adipose tissue expansion. (ugr.es)
Nevertheless, there was some controversy since some authors claim that mast cells exacerbate the inflammatory response in adipose tissue during T2D while others claim that mast cells play a beneficial role. (ugr.es)
The first chapter of this thesis manuscript shows that T2D reduce the number of mast cells in adipose tissue and the surface abundance of some important proteins for their physiological functioning: CD45, CD117, FceRI, and CD203c. (ugr.es)
Therefore, contrary to previous notions, mast cells do not appear to be central drivers of adipose tissue inflammation in T2D. (ugr.es)
The TME plays a pivotal role in CRC, encompassing a complex interplay of immune cells, stromal components, and signaling molecules that are essential for tumor origin and progression. (ugr.es)
One explanation for deficient repair is when undifferentiated adult stem repair cells are inadequate in number or cannot be stimulated within the damaged tissue site. (journalofprolotherapy.com)
1, 2 Recently, Prolotherapists have begun to utilize the potential of autologous adipose (fat)-derived stem/stromal cells (AD-SC) within non-manipulated fat graft scaffolding, combined with high-density PRP concentrates (HD-PRP) to provide a potent biological therapeutic combination. (journalofprolotherapy.com)
Recognition of the vast number of undifferentiated cells associated with the stromal vascular fraction has resulted in extensive research demonstrating the heterogeneity of such cells, and their ability to participate in production of all mesodermal-derived tissues. (journalofprolotherapy.com)
7 There has been some variation and question regarding the correct terminology for this population of stromal adipose cells. (journalofprolotherapy.com)
At first, the mesenchymal stem cell was thought to be the primary component of this undifferentiated cell type, however it is now evident that within the adipose extracellular matrix are also adipocytic precursors (known as progenitor cells) adherent to adipocytes, and in close approximation to a variety of additional undifferentiated multipotent and pluripotent cells, including pericytes and endothelial cells, all thought to play important roles in mesenchymal-stromal derived tissue regeneration. (journalofprolotherapy.com)
Therefore we have chosen to use the term "adipose-derived stem/stromal cells" (AD-SC's), rather than simply "mesenchymal stem cells. (journalofprolotherapy.com)
Interestingly, a small subset of capillary endothelial cells within white and brown fat also express this marker, suggesting a contribution of specialized endothelial cells to the adipose lineage. (elsevierpure.com)
2017). MMP-2 and MMP-14 Silencing Inhibits VEGFR2 Cleavage and Induces the Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells to Endothelial Cells. (sciendo.com)
Comparison of human mesenchymal stromal cells from four neonatal tissues: Amniotic membrane, chorionic membrane, placental decidua and umbilical cord. (sciendo.com)
Equine mesenchymal stem cells from bonemarrow, adipose tissue and umbilical cord:immunophenotypic characterization anddifferentiation potential. (sciendo.com)
Osteogenic proliferation and differentiation of canine bone marrow and adipose tissue derived mesenchymal stromal cells and the influence of hypoxia. (sciendo.com)
Adipose stem cells in reparative goat mastitis mammary gland. (sciendo.com)
Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stem Cells from Sheep: Culture Characteristics. (sciendo.com)
Recently, the endocrine activity of adipose tissue cells has been intensively studied. (123dok.org)
The TME consists of various cellular components, including immune cells, stromal cells, and extracellular matrix, along with soluble factors and signaling molecules. (biomedcentral.com)
These checkpoints act as molecular brakes on immune cells, preventing excessive activation and potential damage to healthy tissues. (biomedcentral.com)
In mammals, there are two functionally unique types of excess fat: white adipose cells (WAT), which is usually specific for energy storage space, and brownish adipose cells (Softball bat), which dissipates energy for thermogenesis1,2 via the activity of uncoupling proteins 1 (UCP1). (liveconscience.com)
Nevertheless, whether these Betrixaban supplier guns recognized in mouse cells can unambiguously define different types of human being adipose progenitors is usually presently unfamiliar. (liveconscience.com)
To define molecular and practical features of particular adipose progenitors, we generated human being preadipocyte put cell populations produced from a total of four human being topics by separating cells from the stromal vascular portion (SVF) of human being throat excess fat and immortalizing them via steady manifestation of human being telomere invert transcriptase (hTert)27 (Supplementary Fig. 1a). (liveconscience.com)
To assess the capacity of multipotent stromal cells (MSC) to induce the generation of Tregs, transwell co-cultures were performed as well as cultures with MSC-conditioned medium (CM). In short, peripheral blood mononuclear cells (PBMC) were co-cultured with allogeneic MSC or CM for one week followed by one week of culture in the absence of MSC. (bio-protocol.org)
To assess the effect of multipotent stromal cells (MSC) on monocytes, 3-day cultures were performed of freshly isolated monocytes in MSC-conditioned medium (CM). As a control condition, monocytes were stimulated with low dose macrophage colony-stimulating factor (M-CSF). (bio-protocol.org)
To effectively support the growth and differentiation of primitive lymphohematopoietic progenitors, complex signals from stromal cells are important. (bio-protocol.org)
Several stromal cell lines are known to support both lymphoid and myeloid cells simultaneously in mouse. (bio-protocol.org)
Generating mouse multipotent stromal cells (MSC) from bone-marrow cells is usefull for a wide range of applications. (bio-protocol.org)
Using osteogenic differentiation medium, multipotent stromal cells (MSC) are induced to differentiate into osteocytes in vitro and to secrete bone matrix. (bio-protocol.org)
We use auricular cartilage as an exemplar to illustrate how the use of tissue-specific adult stem cells, assembly through additive manufacturing and improved understanding of postnatal tissue maturation will allow us to more accurately replicate native tissue anisotropy. (biomedcentral.com)
Group 2 innate lymphoid cells (ILC2s) adapt to tissue physiology and contribute to immunity, inflammatory pathology and metabolism. (elifesciences.org)
This important study describes the protective role of group 2 innate lymphoid cells (ILC2s) in tissue physiology and contributes to immunity, inflammatory pathology, and metabolism in maintaining homeostasis during pregnancy. (elifesciences.org)
Both heterogeneity and tissue specialization of immune cells may hold the key to understanding the pathophysiology of some important pregnancy complications, such as miscarriage and fetal growth restriction (FGR), which is defined as the failure of the fetus to achieve its genetically determined growth potential. (elifesciences.org)
Despite often comprising only a small proportion of tissue resident immune cells, ILCs are present in most tissues and have been shown to orchestrate inflammatory responses to viruses, intracellular bacteria and parasites. (elifesciences.org)
Adipocytes are the main constituent cells of adipose tissue. (frontiersin.org)
Conditioned medium from adipose derived stem cells (ADSC-CM) stimulates both collagen synthesis and migration of fibroblasts, and accelerates wound healing in vivo. (indexindex.com)
Recently, the production and secretion of growth factors has been identified as an essential function of adipose-derived stem cells (ADSCs). (indexindex.com)
City of Hope's Train, Educate and Accelerate Mastery of Stem cell research (TEAMS) program was built around four key areas of regenerative medicine research: Cancer Stem Cells, Hematopoietic Stem Cells, Tissue-Specific Stem Cells and Human Pluripotent Stem Cells. (ca.gov)
Four trainees worked within the field of Tissue-Specific Stem Cells. (ca.gov)
Given this, the ALINE MANICA2 cryopreservation of adipose tissue-derived mesenchymal stem cells (ADMSCs) could be a JULIANA CRISTINA SCHMIDT2 way to collect them in one surgical procedure and after performing fractional fat grafting. (bvsalud.org)

Stromal vascular progenitors in adult human adipose tissue. (ixcellsbiotech.com)
In this study, we label committed murine adipose progenitors through expression of GFP from the genetic locus for Zfp423, a gene controlling preadipocyte determination. (elsevierpure.com)
In this protocol, we introduce two stromal co-culture systems for murine lymphohematopoietic progenitors and their application for limiting dilution assays. (bio-protocol.org)

In this review, we discuss the potential influence of stromal vascular fraction from adipose tissue in the management of alopecia as well as its involvement in preclinical and clinical trials. (jcadonline.com)
however, a variety of other cell types are found as well, collectively labeled as stromal vascular fraction (SVF). (jcadonline.com)
Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation. (ixcellsbiotech.com)

Under physiological conditions, the main- PPARγ mutation has been shown to link to familial partial lipody- tenance of normal adipose tissue mass is mainly the result of a strophy, a clinical disorder characterized by the loss of adipose balance of lipid storage and lipolysis (Bouchard et al. (deepdyve.com)

Use of a chronic model of articular cartilage and meniscal injury for the assessment of long-term effects after autologous mesenchymal stromal cell treatment in Steep. (sciendo.com)

Adipocytes arise from the commitment and differentiation of adipose precursors in white adipose tissue (WAT). (nih.gov)
In the past decade, better understanding of the cellular mechanisms responsible for successful soft tissue augmentation has been reported, focusing on the plentiful undifferentiated stromal elements rather than the survival of mature adipocytes. (journalofprolotherapy.com)
The existence of dark brown, beige, and white adipocytes as well as probably various other unknown adipose cell types features the heterogeneity of adipose tissues depots, which links to their different features in energy metabolism potentially. (liveconscience.com)

Another key aspect of adipose tissue is the thermogenic capacity ( 11 - 13 ) of brown adipose tissue (BAT), which means dissipation of excess energy in the form of heat. (bmbreports.org)
Another major adipose tissue subtype, brown adipose tissue, is present around kidneys, adrenals, and aorta, as well as within the mediastinum and neck. (123dok.org)
In adult humans, brown adipose tissue is very scarce and probably not functional. (123dok.org)

Obesity is defined as an excess accumulation of white adipose tissue associated with a low grade inflammation which is one contributor to obesity complications such as diabetes. (springer.com)
In the first one, local adipose tissue hypoxia could induce fibrosis accumulation which in turn through adipocyte dysfunctions might provoke adipose tissue inflammation. (springer.com)
In the second one, fibrosis could be a result of local adipose tissue inflammation induced by tissue expansion. (springer.com)
Obesity is defined as an expansion of white adipose (WAT) tissue that is associated with low grade inflammation which possibly contributes to the development of health complications such as diabetes, liver pathologies, dyslipidemia, cardiovascular diseases as well as some cancers [ 2 - 4 ]. (springer.com)
1 In RA, numerous cytokines play a fundamental role in inflammation and joint destruction and are thought to originate primarily from synoviocytes and leucocytes that massively infiltrate synovial tissue. (bmj.com)
Our study also showed that Ucp2 deletion alleviates HFD-induced weight gain and adipose tissue inflammation by blocking adipocyte apoptosis, an event preceding the recruitment of macrophages and proinflammatory cytokine secretion. (bmbreports.org)
Angiogenesis, critical for a physiological adipose tissue expansion, is compromised in T2D, contributing to hypoxic stress and inflammation. (ugr.es)
analyses, as well as others (8-11), support the hypothesis that adipose tissue-secreted factors may indeed be potent modulators of inflammation-related disorders such as obe- sity, type 2 diabetes, metabolic syndrome, atherosclerosis, inflammatory bowel disease, thyroid-associated (Graves') ophthalmopathy, breast cancer, and nonalcoholic fatty liver disease. (123dok.org)
Current tissue-engineered auricular constructs implanted into immune-competent animal models have been observed to undergo inflammation, fibrosis, foreign body reaction, calcification and degradation. (biomedcentral.com)

With improved understanding of tissue healing and regeneration, stem cell Prolotherapy is gaining significant clinical importance and potential. (journalofprolotherapy.com)

Fibrosis is characterized by an excessive accumulation of extracellular matrix components which could result in tissue dysfunction. (springer.com)
Extracellular matrix is a fibrillar network composed of structural (collagens) and adhesion (fibronectin) proteins crucial for tissue architecture and biological pathway Histol Histopathol 27:1515-1528, 2012 . (springer.com)
The extracellular matrix is essential for the architecture of the tissue and a myriad of associated biological functions. (springer.com)

Recently, we and others have demonstrated fibrotic depots in white adipose tissue of obese subjects. (springer.com)
Zfp423 GFP mice represent a simple tool for the specific localization and isolation of molecularly defined preadipocytes from distinct adipose tissue depots. (elsevierpure.com)

Objectives (1) To compare spontaneous and stimuli-induced adipocytokine secretion by articular adipose tissue (AAT) and synovial membrane (SM) explants obtained from patients with rheumatoid arthritis (RA). (bmj.com)
It was found that the selective loss of white adipose tissue occurred through increased secretion of sebum, an oily substance produced by the skin for skin barrier function. (abrax-japan.com)

Tumor stroma promotes tumor proliferation, invasion, and metastasis, but how stromal lipids influence these processes remain to be defined. (aacrjournals.org)
This study showed that stromal CAVIN1 suppresses prostate cancer metastasis by modulating tumor microenvironment, lipid content, and inflammatory response. (aacrjournals.org)
The tumor has the following three components: epithelial cell, myoepithelial cell, and stromal/mesenchymal. (medscape.com)
Research has shown that some solid tumors are stiffer than their surrounding tissues, and tumor stiffness is related to solid tumor progression and aggression [ 7 , 8 ]. (ijbs.com)

White adipose tissue is increased in obese (BMI ≥ 30 kg/m2) women and the dysfunction resulting from adipocyte hyperplasia and hypertrophy as well as the increase in visceral and ectopic fat results in an increase in local and often systemic pro-inflammatory cytokines and bioavailable estrogen. (ku.edu)
Conditional gene targeting has been extensively used for in vivo analysis of gene function in adipocyte cell biology but often with debate over the tissue specificity and the efficacy of inactivation. (diabetesjournals.org)
Thus, different "adipocyte-specific" Cre lines display different degrees of efficiency and specificity, illustrating important differences that must be taken into account in their use for studying adipose biology. (diabetesjournals.org)
Adipocyte Senp2 de﫿ciency resulted in less adipose lipid storage accompanied by an ectopic fat accumulation and insulin resistance under high-fat diet feed- ing. (deepdyve.com)
Although less fat stor- adqcKO pose lipid storage in adipocyte-speci﫿c Senp2 knockout mice fed age was shown in Senp2 adipose tissues, the increased with high-fat diets (HFD). (deepdyve.com)
Therefore, adipocyte-speci﫿c remain in adipose tissues. (deepdyve.com)

In his study, Dr. Kambayashi discovered that over-expression of TSLP in obese mice can selectively induce reduction in white adipose tissue. (abrax-japan.com)

2010). Senp2 also regulates fatty acid metabolism in skeletal Downloaded from https://academic.oup.com/jmcb/article-abstract/10/3/258/4763638 by Ed 'DeepDyve' Gillespie user on 26 June 2018 Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1 j 259 muscle (Koo et al. (deepdyve.com)

Highly dense tissues, such as bone or kidney stones, readily reflect echoes and, therefore, appear bright white on an ultrasound image. (medscape.com)
Thus, substances with widely differing densities (eg, air, bone) may appear bright white on an ultrasound image. (medscape.com)

Excessive accumulation of white adipose tissue is associated with increased risk of diabetes, cardiovascular disease, and stroke. (abrax-japan.com)
Previous studies showed that P-selectin-mediated platelet accumulation in CRC tissue may up-regulate LOX expression. (ijbs.com)

Importantly, those changes were more prominent in the omental (o-WAT) than in the subcutaneous white adipose tissue (s-WAT). (ugr.es)

Carbon-containing particulates accumulate with age in a subset of macrophages in human lung-associated lymph nodes, decrease macrophage phagocytic capacity and turnover and disrupt lymphoid tissue structure, potentially compromising adaptive immune responses. (nature.com)

A essential obstacle for these research is usually the absence of human-derived brownish and white excess fat progenitor cell versions. (liveconscience.com)

Beiging and thermogenesis in white adipose tissue (WAT) is an important adaptive response to cold exposure, but how the brain senses cold and subsequently induces beiging remains unclear. (nature.com)

Furthermore, we show that in maintaining early adipose precursors, Sox9 activates Meis1, which prevents adipogenic differentiation. (nih.gov)

Selection of GFP-expressing fibroblasts from either subcutaneous or visceral adipose-derived stromal vascular cultures isolates stably committed preadipocytes that undergo robust adipogenesis. (elsevierpure.com)

It has been found that some of the SVF cell types possess regenerative and anti-inflammatory potentials in damaged tissues due to their ability to secrete growth factors and anti-inflammatory molecules. (jcadonline.com)
Recent advances in regenerative medicine place us in a unique position to improve the quality of engineered tissue. (biomedcentral.com)
Combining biomimetic regenerative medicine strategies will allow us to improve tissue-engineered auricular cartilage with respect to biochemical composition and functionality, as well as microstructural organization and overall shape. (biomedcentral.com)
Due to recent advances in regenerative medicine and additive manufacturing we are entering into an age where we have the potential to replace 'like with like', by improving the quality of engineered tissue with respect to biochemical composition and functionality, as well as microstructural organization and overall shape. (biomedcentral.com)
We will use the lessons learnt from auricular cartilage tissue engineering to illustrate how combining additive manufacturing and regenerative medicine for tissue-engineering purposes can be used to create functional and durable tissue with potential to shift the paradigm in reconstructive surgery. (biomedcentral.com)

Tissue explants were treated with proinflammatory cytokines relevant to RA pathogenesis (interleukin 1β (IL-1β), tumour necrosis factor (TNF), interferon γ, IL-15, IL-17, IL-23). (bmj.com)
Conclusion Rheumatoid AAT is highly reactive tissue which upon stimulation secretes considerable amounts of proinflammatory (IL-6, IL-8, TNF) and anti-inflammatory (IL-1Ra) cytokines and classical adipokines. (bmj.com)
Recently, adipose tissue has been shown to synthesise and release highly bioactive substances: classical adipokines (eg, leptin, adiponectin) and various proinflammatory factors such as cytokines, chemokines, growth factors and complement components. (bmj.com)
They respond to IL-25, IL-33 and TSLP and produce both amphiregulin, which is involved in tissue repair, and classical type-2 cytokines including IL-4, IL-5 and IL-13. (elifesciences.org)

In the present study, we have investigated the role of Ucp2 against high-fat diet (HFD)-induced obesity in epididymal white adipose tissue (eWAT) and browning of inguinal white adipose tissue (iWAT). (bmbreports.org)
To study the role of Ucp2 in adipose tissue, we have examined HFD-induced obesity and β3 adrenergic stimulation in Ucp2 KO mice. (bmbreports.org)
We have demonstrated that Ucp2 deletion dysregulates adipose tissue homeostasis under diet-induced obesity (DIO), but does not affect the browning of white adipose tissue (WAT). (bmbreports.org)
In this study, we observed the overexpression of SUMO-speci﫿c protease 2 (Senp2) in adipose tissues during obesity. (deepdyve.com)

Standard monolayer cell culturing on tissue culture plastic has notably improved our understanding of basic cell biology, but it does not replicate the complex 3D architecture of in vivo tissue, and it can significantly modify cell properties. (wikipedia.org)
One of the challenges in generating in vivo like cultures or tissue in vitro is the difficulty in co-culturing different cell types. (wikipedia.org)
However, Ucp2 displays a wide tissue expression range ( 5 ), and its roles in various tissues and cell types have not been covered. (bmbreports.org)
We also point out a possible contribution of adipose tissue-associated mast cell secre- tory activity to the development of these diseases. (123dok.org)
Here we provide a comprehensive protocol on how to isolate and culture individual cell types from whole endometrial tissues for use in in vitro experiments. (bio-protocol.org)
The varying proportion of these cell types as well as the stromal components accounts for the morphologic diversity of these tumors. (medscape.com)
The combined efforts of cell biologists, material scientists, tissue engineers and reconstructive surgeons and associated converging technologies [ 1 ] in the 21st century have put us in an enviable position compared with our predecessors. (biomedcentral.com)
Current research in tissue engineering is geared towards elucidating the appropriate compositional elements (biomaterials, biomolecules and cell sources) as well as methods of assembly. (biomedcentral.com)

Insuf﫿cient adipose lipid storage is asso- ciated with many pathological conditions including hyperlipidemia, insulin resistance, and type 2 diabetes. (deepdyve.com)

Here, we show that stromal CAVIN1 regulates lipid abundance in the prostate cancer microenvironment and suppresses metastasis. (aacrjournals.org)
11 However, the greater the abundance of adipose tissue in the human body, the significantly higher the yield of MSCs is compared to other tissues. (jcadonline.com)

These results revealed the crucial role of Senp2-Setdb1 axis in controlling adipose lipid storage. (deepdyve.com)
Excess or insuf﫿cient lipid storage in generation of the intermediate species of diacylglycerol (DAG) adipose tissues would impair nutrient homeostasis, which is and monoacylglycerol (MAG) (Young and Zechner, 2013). (deepdyve.com)

Immunohistochemistry for Zfp423-driven GFP expression in vivo confirms a perivascular origin of preadipocytes within both white and brown adipose tissues. (elsevierpure.com)

Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver. (umassmed.edu)

Adipose tissue plays an important role in metabolism through its storage and release of triglycerides, peptide hormones (adipokines) and other proteins, and in the case of brown fat, for its role in thermogenesis ( 1 ). (diabetesjournals.org)
In effect, a wide range of exported secretory proteins, dubbed adipokines, have been identified as constituents of the adipose proteome (adipokinome). (123dok.org)

In studying adipogenesis, precursor markers, including Pref-1 and PDGFRα, are used to isolate precursors from stromal vascular fractions of WAT, but the relation among the markers is not known. (nih.gov)
adipose precursors. (nih.gov)

The first tissue-engineered, ear-shaped appendages made from bovine chondrocytes and biocompatible scaffolds by the Vacanti group were prone to deformation when xenografted onto immune-compromised mice, highlighting the lack of long-term stability [ 6 ]. (biomedcentral.com)

4 5 Adipose tissue is an active endocrine organ, heterogeneous with respect to embryonic origin, body distribution and function. (bmj.com)

However many more pro and anti-inflammatory mediators produced by the adipose tissue have been described since then. (springer.com)

Our study also demonstrates the Pref-1 promoter-rtTA system for inducible gene inactivation in early adipose precursor populations. (nih.gov)

Lymph nodes are small organs that are distributed throughout the body and drain lymph fluid from the tissues. (nature.com)
Rare or unusual sites of occurrence may be attributable to ectopic salivary gland tissue (eg, in the mandible, neck lymph nodes, or axilla). (medscape.com)

El primer capítulo discute el impacto de la diabetes tipo 2 (T2D) en los mastocitos del tejido adiposo, mientras que el segundo capítulo se centra en las dinámicas de poblaciones y los cambios fenotípicos de los neutrófilos, eosinófilos, células dendríticas plasmacitoides, células dendríticas convencionales y mastocitos en el cáncer colorectal (CRC). (ugr.es)
tissue stiffness, LOX, colorectal cancer. (ijbs.com)

3 In veterinary medicine, AD-SC's have been utilized effectively for over ten years in the treatment of osteoarthritic joints 4, 5 and connective tissue injuries, showing an over 80% success rate in blinded placebo controlled canine clinical trials. (journalofprolotherapy.com)

PDK4 also enhances glycerol synthesis in white adipose tissue by shunting pyruvate into glycero neogenesis, at least inside the fed state. (nartpathway.com)

In this study, we investigated the relevance of ECM stiffness to clinicopathologic features using human CRC tissue microarrays. (ijbs.com)

Anatomy42

Organisms13

Diseases26

Chemicals and Drugs87

Analytical, Diagnostic and Therapeutic Techniques and Equipment41

Psychiatry and Psychology2

Phenomena and Processes55

Disciplines and Occupations1

Technology, Industry, Agriculture4

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Named Groups2

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Cells62

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Normal adipose tissue1

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Adipocytes3

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Inflammation9

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Tumor4

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Obese1

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Induces1

Differentiation1

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