Animal Use AlternativesStrokeDisease Models, AnimalModels, AnimalBrain IschemiaCerebrovascular DisordersCerebral HemorrhageCerebral InfarctionRisk FactorsIschemic Attack, TransientTime FactorsMice, Inbred C57BLFibrinolytic AgentsNeuroprotective AgentsTreatment OutcomeParesisProspective StudiesStroke, LacunarBrainStroke VolumeAcute DiseaseTissue Plasminogen ActivatorRecovery of FunctionBrain InfarctionInfarction, Middle Cerebral ArteryFollow-Up StudiesHuntington DiseaseThrombolytic TherapyIntracranial HemorrhagesNeurodegenerative DiseasesIncidenceMice, TransgenicCohort StudiesHeat StrokeMagnetic Resonance ImagingIntracranial EmbolismHemiplegiaNervous System DiseasesMice, KnockoutSeverity of Illness IndexTomography, X-Ray Computed