Stroke conclusions models cardiovascular. Medical search. Frequent questions

Together with evidence from a meta-analysis of RCTs demonstrating that blood pressure-lowering drugs reduce the risk of high-burden cardiovascular diseases, we believe this constitutes moderately strong evidence that the intervention reduces the risk of cardiovascular events and deaths. (givewell.org)
Salt substitution is inexpensive and likely reduces the risk of high-burden cardiovascular diseases, yet its ongoing cost constrains its cost-effectiveness. (givewell.org)
Coffee consumption and mortality from cardiovascular diseases and total mortality: Does the brewing method matter? (coffeeandhealth.org)
ABSTRACT Chronic (noncommunicable) diseases, such as cardiovascular disease, stroke, cancer and diabetes mellitus, are a global public health problem that is increasing, particularly in developing countries. (who.int)
Secondhand smoke causes many of the same diseases as direct smoking, including cardiovascular diseases, lung cancer, and respiratory diseases. (wikipedia.org)
Bus drivers are known to be highly at risk of cardiovascular diseases. (biomedcentral.com)
Cardiovascular diseases and related complications are the leading causes of death worldwide and are projected to gradually increase in the near future [ 1 ]. (biomedcentral.com)
In 2014, 355 workers were compensated for a work-related disease due to cardiovascular and neurovascular diseases in Korea [ 4 ]. (biomedcentral.com)
Commercial drivers are known to carry diverse health problems, such as cardiovascular diseases. (biomedcentral.com)
Being an exception of the labor standard act that prevents workers from working over 12 h a day in Korea, investigations on bus drivers in South Korea showed long working hours, which is a considerable risk factor of cardiovascular diseases [ 17 ]. (biomedcentral.com)
Remnant cholesterol (RC) reportedly mediates residual cardiovascular risk in atherosclerotic cardiovascular diseases (ASCVD). (qxmd.com)
The outcome events were cardiovascular diseases (CVDs), while the independent variable was total daily physical activity. (biomedcentral.com)
Elevated levels of homocysteine, termed hyperhomocysteinemia (HHcy), is considered a risk factor for cardiovascular and cerebrovascular diseases [ 7 ]. (biomedcentral.com)
Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases (CVD). (hindawi.com)
The sample consisted of 334 (14%) of the 2354 pharmacies in Ankara, and 24 essential medicines for cardiovascular diseases, diabetes, chronic respiratory diseases, and palliative care, adopted from the WHO Model List of Essential Medicines (2021). (who.int)
ATSDR received considerable assistance in this work from the Cardiovascular Diseases Branch of the Centers for Disease Control & Prevention (CDC). (cdc.gov)
Many cardiovascular diseases evolve from a phenomenon called atherosclerosis. (lu.se)
This marker measures the thickness of the wall of the carotid arteries and can predict the possibility of developing cardiovascular diseases later on in life. (lu.se)
Stroke, like many other cardiovascular diseases, can be influenced by modifiable lifestyle factors, such as diet. (lu.se)
The most common cause of mortality worldwide is cerebrovascular disease (CVD), which includes coronary heart disease (CHD), congestive heart failure, CVD and stroke, peripheral artery diseases, carotid artery diseases, and aortoiliac disease. (medscape.com)
[ 5 , 7 ] Although the underlying mechanisms are complex, the chronic inflammatory state and microbial burden in people with periodontal disease may predispose them to cardiovascular diseases in ways proposed for other infections. (medscape.com)
In this capacity, she has worked across federal and private partners to execute evidence-based strategies to prevent cardiovascular diseases and improve health. (cdc.gov)
The NCD-GAP provides a road map and a menu of policy options for all Member States and other stakeholders to take coordinated and coherent action, at all levels, local to global, to attain the nine voluntary global targets, including that of a 25% relative reduction in premature mortality from cardiovascular diseases, cancer, diabetes or chronic respiratory diseases by 2025. (who.int)

The model incorporated population-representative data from India on multiple risk factors that affect myocardial infarction and stroke mortality, including hypertension, hyperlipidemia, diabetes, coronary heart disease, and cerebrovascular disease. (who.int)
To provide evidence of the relationship of Mediterranean diet (MD) on incidence/mortality for cardiovascular disease (CVD), coronary/ischemic heart disease (CHD)/acute myocardial infarction (AMI) and stroke (ischemic/hemorrhagic) by sex, geographic region, study design and type of MD score (MDS). (nih.gov)
The target population consists of working-age people who are considered high-risk for cardiovascular disease events because of a history of coronary heart disease. (ahdbonline.com)
Using Framingham risk scoring system, the probability of myocardial infarction or stroke events was calculated for a representative sample population, ages 35 to 69 years, of people at high risk for cardiovascular disease, with a history of coronary heart disease. (ahdbonline.com)
The high-risk cohort (those with coronary heart disease) comprises 4% of the 35- to 69-year-old commercially insured population but generates 22% of the risk for coronary heart disease and stroke. (ahdbonline.com)
1 Hypercholesterolemia, particularly elevated lowdensity lipoprotein cholesterol (LDL-C), is strongly associated with an increased risk of CVD, including coronary heart disease (CHD) events (ie, myocardial infarction [MI], angina, coronary revascularization) and stroke. (ahdbonline.com)
A recent study has found that a ceramide- and phospholipid-based risk score, not LDL cholesterol (LDL-C), can efficiently predict residual cardiovascular disease (CVD) event risk in patients with coronary heart disease (CHD). (hcplive.com)
While investigators concluded that ceramide-phospholipid risk score showed comparable and synergistic predictive performance when compared with previously published CVD risk models, they also found that there was variability in the risk of CVD events in patients with coronary artery disease. (hcplive.com)
Coronary heart disease (CHD) events, ischaemic stroke events, and total mortality. (mja.com.au)
A worked example is given calculating the 10-year coronary heart disease risk for a 57 year-old non-diabetic male with no personal or family history of cardiovascular disease, who smokes 30 cigarettes a day and has a systolic blood pressure of 137 mmHg, a total cholesterol (TC) of 6.2 mmol/l, a high density lipoprotein (HDL) of 1.3 mol/l, and a body mass index of 21. (biomedcentral.com)
Most CVD models focus on coronary heart disease (CHD) events, such as myocardial infarction. (biomedcentral.com)
At least 200 statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental coronary artery calcium (CAC) on a prior non-gated chest CT will be enrolled across the Stanford Healthcare System and the Palo Alto Veteran's Affairs Healthcare System. (stanford.edu)
CV events were defined as: CV-death, stroke, myocardial infarction, coronary artery bypass graft, or percutaneous coronary intervention. (ox.ac.uk)
In about 74% (411) of cardiovascular disease events the principal diagnosis was coronary heart disease. (bmj.com)
Patients with chronic coronary artery disease (CAD) and/or peripheral artery disease (PAD) have increased risks for cardiovascular (CV)-related morbidity and mortality. (ahdbonline.com)
Associations were nonstatistically significant in meta-analyses of loss-of-function alleles and all-cause mortality, acute coronary syndromes, stroke, and bleeding events. (ahrq.gov)
Although a recent joint society scientific statement (the American Association of Cardiovascular Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology) suggests home-based cardiac rehab (CR) is appropriate for low- and moderate-risk patients, there are no paradigms to define such individuals with coronary heart disease. (journaltocs.ac.uk)
We reviewed a decade of data from all patients with coronary heart disease enrolled in a single CR center (University of Michigan) to identify the prevalence of low-risk factors, which may inform on consideration for participation in alternative models of CR. (journaltocs.ac.uk)
In this observational study, we provide a first paradigm of identifying factors among coronary heart disease patients that may be considered low-risk and likely high-gain for participation in alternative models of CR. (journaltocs.ac.uk)
PA can provide a wide range of favorable response in cardiovascular system such as improving the dynamics of cardiovascular system and reducing the prevalence of coronary heart disease and cardiomyopathy [ 7 ]. (biomedcentral.com)
Most recently, in The Health Consequences of Involuntary Exposure to Tobacco Smoke (HHS, 2006), it concluded that exposure to secondhand smoke could have immediate adverse effects on the cardiovascular system in adults and that it causes coronary heart disease. (nationalacademies.org)
2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)
In paper 1, I set out to summarize observational evidence and further determine the causal relationships between prediabetes and common vascular complications associated with T2D i.e., coronary artery disease (CAD), stroke and renal disease. (lu.se)
therefore, the association between certain periodontal pathogens and coronary artery disease or stroke is gaining more importance. (medscape.com)

The primary aim of this project is to estimate the increase in 6-month statin prescription among statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental CAC on a non-gated chest CT who are randomized to receive notification of their findings vs. usual care. (stanford.edu)
With the increase in aging and cardiovascular risk factors, the morbidity and mortality of atherosclerotic cardiovascular disease (ASCVD), represented by ischemic heart disease and stroke, continue to rise in China. (biomedcentral.com)
Atherosclerotic cardiovascular disease (ASCVD), which mostly involves heart attacks and strokes caused by atherosclerosis, is one of the main causes of death worldwide [ 1 ]. (biomedcentral.com)
Cumulative Remnant Cholesterol Predicts Cardiovascular Outcomes in Elderly Patients with Atherosclerotic Cardiovascular Disease. (qxmd.com)
Risk calculators used were the American College of Cardiology Atherosclerotic Cardiovascular Disease risk calculator (AHA-ASCVD risk), Seattle Heart Failure Model (SHFM risk), and CHA 2 DS 2 VASc. (biomedcentral.com)

Objectives To estimate the effects of nationwide replacement of discretionary salt (used at table or during cooking) with potassium enriched salt substitute on morbidity and death from cardiovascular disease in China. (bmj.com)
We did not identify direct evidence that community salt substitution reduces cardiovascular morbidity or mortality. (givewell.org)
It releases multiple pollutants into the atmosphere, such as PM 2.5 , that has been linked to an increase in cardiovascular morbidity and mortality. (elsevier.es)
This study describes an increase in cardiovascular mortality and morbidity in Spain, due to coal combustion pollutants. (elsevier.es)
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States. (ahdbonline.com)
Cardiovascular morbidity and mortality associated with the metabolic syndrome. (mja.com.au)
The authors add it can take decades to progress to a clinically detectable degree, and thus further follow-up of our cohort is necessary to determine whether a substantial absolute increase in morbidity and mortality from therapy-related cardiovascular disease will emerge. (natap.org)

To model the financial and health outcomes impact of intensive statin therapy compared with usual care in a high-risk working-age population (actively employed, commercially insured health plan members and their adult dependents). (ahdbonline.com)
CONCLUSIONS: Adopting a pharmacist-involved team-based hypertension model could substantially improve BP control and cardiovascular outcomes in the United States. (cdc.gov)
BACKGROUND AND OBJECTIVES: Evidence on the associations between baseline stromal cell-derived factor (SDF)-1 and clinical outcomes in acute ischemic stroke patients is lacking. (bvsalud.org)
The present study aimed to examine the relationship between plasma SDF-1 levels and clinical outcomes based on a large multicenter study of the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS). (bvsalud.org)
The addition of plasma SDF-1 to the conventional risk factors model significantly improved the risk prediction of all outcomes. (bvsalud.org)
In recent years, the mechanism(s) by which excess body weight produces adverse cardiovascular outcomes has attracted interest, with one potential pathway being the dysfunction of adipose tissue. (nature.com)
In the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) clinical trial of such patients, rivaroxaban plus aspirin demonstrated a significant reduction in major adverse CV events (MACE), a composite of stroke, myocardial infarction, and CV death, and major adverse limb events (MALE), a composite of chronic and acute limb ischemia, and major amputation resulting from vascular events, versus aspirin alone. (ahdbonline.com)
Outcomes included a composite of MACE (stroke, unstable angina pectoris, myocardial infarction, and cardiac death). (qxmd.com)
Long-term cumulative RC was independently associated with incident MACE in elderly participants with ASCVD, suggesting that achieving and maintaining optimal RC levels later in life may still improve cardiovascular outcomes. (qxmd.com)
Sensitivity analyses under recessive and additive models for the two outcomes with adequate data (major adverse cardiovascular events and stent thrombosis) produced results in the same direction but with larger effect sizes than the dominant model. (ahrq.gov)
The outcomes were upper limb sensorimotor function, health-related quality of life, level of independence, cardiovascular effects, and adverse events. (karger.com)
Therefore, understanding the dietary risk factors for cardiovascular outcomes is important in order to establish nutritional recommendations. (lu.se)
Discussed accomplishments of Million Hearts, state how evidence-based strategies can help identify and address the needs of those at greatest risk for heart attack and stroke, and discuss the use of standardized treatment approaches to improve outcomes for patients at risk for heart attack and stroke. (cdc.gov)

Despite the rise in co-morbid cardiovascular disease risk factors like hyperlipidemia and hypertension in low- and middle-income countries, tobacco control is likely to remain a highly effective strategy to reduce cardiovascular deaths. (who.int)
We have constructed and validated a tool to quantify the risk of a cardiovascular event based on age, diastolic hypertension and PR3 ANCA status in patients without prior CV disease. (ox.ac.uk)
This investigation has examined a possible role for the renin-angiotensin system as well as body mass and insulin values in mediating these cardiovascular and renal aspects of the hypertension syndrome. (scienceopen.com)
OBJECTIVE: The objective of this study was to assess the potential health and budgetary impacts of implementing a pharmacist-involved team-based hypertension management model in the United States. (cdc.gov)
Because most patients with hypertension will not have a CVD-related event, we used a 2-part model to analyze medical expenditures. (cdc.gov)
CONCLUSION: This study affirms that self-knowledge of high blood pressure, even among patients who are diagnosed and treated for hypertension, can be improved. (cdc.gov)
Included in this assortment are stroke, aneurysm, damage due to chronic hypoperfusion and damage due to chronic hypertension. (biomedcentral.com)

The Framingham risk score is a robust algorithm to predict cardiovascular disease (CVD) risk based on demographic and clinical factors among European Americans. (cdc.gov)
Reductions in cardiovascular and stroke events reported in clinical trials with aggressive statin therapy were applied to these cohorts. (ahdbonline.com)
Aggressive low-density lipoprotein cholesterol-lowering therapy for working-age people at high risk for cardiovascular events and with a history of heart disease appears to have a significant potential to reduce the rate of clinical events and is cost-neutral for payers. (ahdbonline.com)
Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. (mja.com.au)
In clinical medicine, cardiovascular risk is increasingly accepted as the appropriate criterion to use to identify those who will most benefit from interventions designed to prevent cardiovascular disease and death. (biomedcentral.com)
In modeling the potential impacts of 5 hypothetical new transformative therapies representing diverse patient types, clinical intervention models, and disease burdens, we found substantial and varying gaps between initial and downstream payer impacts. (ajmc.com)
Objective: To investigate the effect of admission serum glucose on the clinical prognosis of patients with acute ischemic stroke receiving intravenous alteplase thrombolysis. (bvsalud.org)
Surveys were linked prospectively to clinical hospital records, and Cox proportional hazards models were used to estimate the risk of cardiovascular disease events or death according to oral hygiene. (bmj.com)
Previous smaller epidemiological studies that have examined the association between oral health and cardiovascular disease have generally used clinical assessments to identify periodontal disease. (bmj.com)
HHcy is a significant clinical risk factor for stroke, cardiovascular disease and type 2 diabetes. (biomedcentral.com)
Reduction of total cholesterols (TC) and LDL-C by dietary alterations and medications that affect lipid metabolism [ 14 ] is found to reduce the occurrence of atherosclerosis in animals and clinical cardiovascular events in human [ 15 ]. (hindawi.com)
The addition of key condition-specific clinical data points at the time of hospital admission will dramatical y improve model performance. (who.int)

This inverse association includes CHD and ischemic stroke, but apparently not hemorrhagic stroke. (nih.gov)
Benefits included reduced nonfatal myocardial infarction and ischemic stroke. (healthpartners.com)
RESULTS: Higher plasma SDF-1 levels were not associated with recurrent stroke, cardiovascular events, and all-cause mortality at one-year after ischemic stroke (all P trend ≥ 0.05). (bvsalud.org)
Methods: Patients with acute ischemic stroke who received intravenous alteplase thrombolysis between January 2016 and December 2017 were enrolled. (bvsalud.org)

Pooled relative risks (RRs) were calculated using random-effects models. (nih.gov)
Smoothed census tract relative risks were calculated using the Besag-York-Mollié model. (bmj.com)
DESIGN, SETTING, AND PARTICIPANTS: Microsimulation modeling was used to estimate long-term benefits and harms for hypothetical US cohorts of men and women aged 40 to 79 years with up to 20% 10-year risk for an atherosclerotic CVD event and without prior history of CVD or elevated bleeding risks. (healthpartners.com)
We planned to determine cardiovascular disease prevalence and their risks on bus drivers and compared the results to that of general workers using Korean National Health Insurance data. (biomedcentral.com)
In the same study, fewer than 20 % of primary care providers routinely calculated 10 year cardiovascular risks in their patients [ 3 ]. (biomedcentral.com)
A prospective study published last month found that even short activity bouts of a few minutes a day may lower risks for heart attack, stroke , and early death. (medscape.com)
1974). In addition, the 1990 report The Health Benefits of Smoking Cessation: A Report of the Surgeon General (HHS, 1990) and the National Cancer Institute's Monograph 8: Changes in Cigarette-Related Disease Risks and Their Implications for Prevention and Control (NCI, 1997) discussed the cardiovascular benefits of smoking cessation. (nationalacademies.org)

These findings suggest that in overweight patients cardiovascular and renal values depend chiefly on body weight and insulin, but that in normal weight hypertensives the renin-angiotensin system may play the major role. (scienceopen.com)
One concern is that treatment of renal anemia might increase stroke risk. (gla.ac.uk)
These specific conditions in the oral cavity may create foci of infection that can affect many other vital systems, such as the cardiovascular and renal systems. (medscape.com)
Prediabetes was associated with CAD and stroke but not renal disease in observational analyses, whilst in the causal inference analyses, prediabetes was only associated with CAD. (lu.se)

A secondary aim was to analyse associations between weight changes and cardiovascular complications and total mortality. (springer.com)
To identify additional predictors of CE, a baseline risk score (CARPREG [Canadian Cardiac Disease in Pregnancy Study] II score) for predicting cardiac complications was calculated for all pregnancies and included in a multivariable logistic regression model. (elsevierpure.com)
Conclusions: Obesity increases the risk of maternal cardiovascular complications in pregnant women with heart disease. (elsevierpure.com)
3 Patients with CAD can have complications such as angina, and are at an increased risk for stroke and myocardial infarction (MI) compared with patients without CAD. (ahdbonline.com)
We identified spleen as an important source of these cardiovascular complications in Hmox1 −/− mice. (springer.com)
Previous studies have reached conflicting conclusions on this issue, some supporting our findings and others not, but an Editorial by Peter Sklar & Henry Mazur says taken in aggregate, the weight of the evidence suggests that HIV-infected patients treated with combination antiretroviral regimens are at increased risk for the development of premature atherosclerotic complications. (natap.org)
Type 2 diabetes (T2D), characterized by chronically elevated blood glucose, is also associated with debilitating complications, high healthcare costs and mortality, with cardiovascular complications accounting for more than half of T2D-related deaths. (lu.se)

Our analysis models the cost impact of aggressive statin therapy for a commercially insured cohort of members at high risk for secondary events from CVD as a result of a history of CHD. (ahdbonline.com)
A multi-center, population-based study from the Atherosclerosis Risk in Communities (ARIC) study of a cohort of 3669 community-dwelling adults aged 61-86 years with no history of cardiovascular disease who reported the use of at least one medication between September 2006 and August 2013 were followed up until August 2015. (usc.edu)
In this community-based cohort of older adults with no prior cardiovascular disease, the use of MACE medications was independently and consistently associated with an increased risk of such events in a dose-response fashion. (usc.edu)
The model was tested using the Wegener's Granulomatosis Etanercept Trial (WGET) cohort. (ox.ac.uk)
The model was validated using the WGET cohort (Area under ROC curve = 0.80). (ox.ac.uk)
The study aimed to evaluate the association between cumulative exposure to RC and incident major adverse cardiovascular events (MACE) by analyzing a cohort of elderly patients with ASCVD. (qxmd.com)
Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using metaanalyses. (surrey.ac.uk)

Many commonly used prescription medications have cardiovascular adverse effects, yet the cumulative risk of cardiovascular events associated with the concurrent use of these medications is unknown. (usc.edu)
We examined the association between the concurrent use of prescription medications with known risk of a major adverse cardiovascular event (MACE) ("MACE medications") and the risk of such events among older adults. (usc.edu)
This finding is plausible because combination antiretroviral therapy can cause adverse metabolic changes that are known risk factors for cardiovascular disease. (natap.org)

The corresponding values were 0.82 (95% CI 0.73-0.92) for ischemic (five studies) and 1.01 (95% CI 0.74-1.37) for hemorrhagic stroke (four studies). (nih.gov)
57 (82.6%) were ischemic strokes and 12 (17.4%) hemorrhagic strokes. (gla.ac.uk)
Because anticoagulant therapy is associated with hemorrhagic risk, the stroke risk calculation is needed to decide whether the risk of stroke outweighs the risk of use of an antithrombotic. (biomedcentral.com)

Main outcome measures Averted deaths from cardiovascular disease, non-fatal events, and disability adjusted life years from a reduction in blood pressure were estimated after implementation of potassium enriched salt substitution. (bmj.com)
A diagnosis of MetS provides additional prediction of CHD events, stroke events, and total mortality beyond that provided by other conventional risk factors. (mja.com.au)
The aim was to investigate the association between COPD exacerbations and severe acute cardiovascular (CV) events in COPD patients with a history of CVD. (ersjournals.com)
Data from patients with COPD (≥40 years), with a hospital-based COPD clinic visit between 2010-2016 (index date) and a hospitalization for CV events (stroke, myocardial infarction) or heart failure (HF) 36 to 6 months prior to index, were linked with nationwide Danish health registries, and followed for COPD exacerbations, CV events and death. (ersjournals.com)
A logistic regression model was applied to estimate odds ratios (OR) with 95% CIs for CV events and death. (ersjournals.com)
A model to predict cardiovascular events in patients with newly diagnosed wegener's granulomatosis and microscopic polyangiitis. (ox.ac.uk)
Possible stroke events were independently adjudicated. (gla.ac.uk)
In multivariable models, female gender, diabetes, history of prior stroke at baseline, higher baseline systolic blood pressure, lower serum albumin and higher C-reactive protein were independently associated with stroke events during follow up. (gla.ac.uk)
We evaluated the associations between plasma SDF-1 levels and one-year recurrent stroke, cardiovascular events, and all-cause mortality using Cox regression models. (bvsalud.org)
There were significant interactions between plasma SDF-1 levels and history of diabetes mellitus on recurrent stroke (P = 0.005), cardiovascular events (P = 0.007) and all-cause mortality (P = 0.04) at one year. (bvsalud.org)
In patients with diabetes mellitus, plasma SDF-1 was significantly associated with an increased risk of recurrent stroke and cardiovascular events after adjustment for confounders. (bvsalud.org)
For example, 1-SD higher log-SDF-1 was associated with a hazard ratio (95% confidence interval) of 1.65 (1.18-2.32) for recurrent stroke and 1.47 (1.08-1.99) for the cardiovascular events, but not all-cause mortality 1.36 (0.96-1.93) at one year. (bvsalud.org)
Results There were a total of 555 cardiovascular disease events over an average of 8.1 (SD 3.4) years of follow-up, of which 170 were fatal. (bmj.com)
8 C reactive protein and fibrinogen are sensitive markers used to evaluate the inflammatory status of an individual, and the results of prospective longitudinal studies indicate that these markers might be useful predictors for future cardiovascular events in various populations. (bmj.com)
Using Morae Recorder software, we timed 30 healthcare providers tasked with calculating the overall risk of cardiovascular events, sudden death in heart failure, and thrombotic event risk in atrial fibrillation. (biomedcentral.com)
PAD ASCVD events, in particular lower limb artery disease, was predominant and requires active diagnosis and intensive management, while controlling modifiable traditional cardiovascular risk factors. (natap.org)
HCV-related factors did not appear to be associated with the risk of cardiovascular events. (natap.org)
An increased risk of cardiovascular disease (CVD) was reported in patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV), without identifying factors associated with atherosclerotic CVD (ASCVD) events. (natap.org)

Conclusion Deprivation and subjective perceptions of physical environmental characteristics are ecologically associated with cardiovascular disease mortality. (bmj.com)
Objective To examine if self reported toothbrushing behaviour is associated with cardiovascular disease and markers of inflammation (C reactive protein) and coagulation (fibrinogen). (bmj.com)

They were experts with international reputations in echocardiography and environmental or cardiovascular epidemiology. (cdc.gov)

In the multivariable model adjusted for traditional cardiovascular risk factors, low-density lipoprotein cholesterol level, and most recent RC level, the hazard ratios for MACE that compared the high and low tertiles of the RC variables were 1.30 (95% confidence interval [CI], 1.16-1.44) for cumulative RC and 1.36 (95% CI, 1.23-1.52) for TWA RC. (qxmd.com)

The aim of this study of type 2 diabetic patients in the Swedish National Diabetes Register was to study the associations of BMI, overweight (BMI 25-29.9 kg/m 2 ) and obesity (BMI ≥ 30 kg/m 2 ) with cardiovascular disease in type 2 diabetes, as these associations have not previously been clarified. (springer.com)
Adjusted hazard ratios (model 1) for CHD, cardiovascular disease and total mortality with overweight were 1.27 (95% CI 1.09-1.48), 1.24 (1.09-1.41) and 1.16 (0.94-1.45), respectively, and 1.49 (1.27-1.76), 1.44 (1.26-1.64) and 1.71 (1.36-2.14) with obesity, as compared with normal weight. (springer.com)
Both overweight and obesity independently increased the risk of CHD and cardiovascular disease in patients with type 2 diabetes. (springer.com)
The aim of the present study, based on data from the Swedish National Diabetes Register, was to describe the associations between BMI, overweight and obesity, fatal or non-fatal CHD, stroke, CVD and total mortality, in female and male type 2 diabetic patients aged 30-74 years. (springer.com)
Cardiovascular disease has been elevated to this position by a combination of factors that include urbanization and its attendant effects, such as obesity, a sedentary lifestyle, changes in dietary habits, and smoking. (revespcardiol.org)
There is growing evidence that early development of obesity increases cardiovascular risk later in life, but less is known about whether there are effects of long-term excess body weight on the biological drivers associated with the atherosclerotic pathway, particularly adipokines, inflammatory and endothelial markers. (nature.com)

2-4 Landmark statin studies targeting LDL-C lowering have shown dramatic reductions in heart attacks, stroke, and cardiac death. (ahdbonline.com)
RESULTS: Offering this intervention could prevent 22.9-36.8 million person-years of uncontrolled BP and 77,200-230,900 heart attacks and strokes in 5 years (83.8-174.8 million and 393,200-922,900 in 20 years, respectively). (cdc.gov)
I'm delighted to welcome you to today's COCA call, high burdens, great opportunities preventing heart attacks and stroke. (cdc.gov)
At the conclusion of today's session, the participant will be able to describe the key components of Million Hearts and the targets that must be met to prevent one million heart attacks and strokes. (cdc.gov)

Methods and Findings A microsimulation model was developed to quantify the differential effects of various tobacco control measures and pharmacological therapies on myocardial infarction and stroke deaths stratified by age, gender, and urban/rural status for 2013 to 2022. (who.int)
Methods: We analyzed data from the Proactive IV IrOn Therapy in HaemodiALysis Patients (PIVOTAL) trial focusing on variables associated with risk of stroke. (gla.ac.uk)

In deterministic sensitivity analyses, with changes to key model inputs and assumptions, net benefits were consistent in the total population and in individuals with chronic kidney disease, with averted deaths outweighing additional deaths. (bmj.com)
Analyses were performed for CV death and a composite CV event endpoint that included CV death, myocardial infarction, and stroke. (hcplive.com)
Analyses were conducted using Cox proportional-hazards models, with adjustment for various individual- and area-level demographic and. (lu.se)
These associations persisted in propensity score-matched analyses and among new users of MACE medications, never users of cardiovascular medications and subgroups of participants with increased risk of MACE. (usc.edu)
We performed analyses to identify variables associated with stroke during follow-up and assessed survival following stroke. (gla.ac.uk)
In general, model reporting should conform to published reporting standards, and attempts should be made to test model validity by using sensitivity analyses. (who.int)

Patients aged 30-74 years with no previous CHD or stroke ( N = 13,087) were followed for a mean of 5.6 years until 2003 for fatal or non-fatal CHD, stroke, cardiovascular disease (CHD or stroke) and total mortality. (springer.com)
Using this newly developed model, we compare the CVD event and cost burden under conventional current therapy to represent the results of intensive statin therapy, which is the current standard of care for high-risk patients. (ahdbonline.com)
It is common to assume that all CHD patients have an equivalent cardiovascular risk, but according to this study this seems not to be the case. (hcplive.com)
Within their conclusion, authors wrote that CERT2 scores offer an easy to use tool for estimation residual risk in patients with CHD. (hcplive.com)
This paper describes a cardiovascular disease (CVD) model which has been developed specifically for use in consultations with patients as an aid to risk communication and to shared decision making. (biomedcentral.com)
Patients with Chronic Obstructive Pulmonary Disease (COPD) have an increased risk of cardiovascular disease (CVD). (ersjournals.com)
To create a prognostic tool to quantify the 5 year cardiovascular (CV) risk in patients with newly diagnosed Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) without pre-morbid CV disease. (ox.ac.uk)
Within 5 years of diagnosis of WG or MPA, 14% of patients will have a cardiovascular event. (ox.ac.uk)
In patients with vasculitis, PR3 ANCA is associated with reduced cardiovascular risk compared to MPO ANCA or negative ANCA status. (ox.ac.uk)
Results: During a median 2.1 years follow-up, 69 (3.2%) patients experienced a first post randomization stroke. (gla.ac.uk)
58% of patients with a stroke event died during follow-up, compared to 23% without a stroke. (gla.ac.uk)
Conclusions: In hemodialysis patients, stroke risk is broadly associated with risk factors previously described to increase cardiovascular risk in this population. (gla.ac.uk)
Results: A total of 138 patients were enrolled, including 79 males (57.24%), with a mean age of (68 ± 12) years and a median baseline National Institutes of Health Stroke Scale (NIHSS) score of 9 (6 to 13.75). (bvsalud.org)
CONCLUSIONS: E-alert v2.0 further increased the use of appropriate thromboprophylaxis in hospitalised cancer patients, although was not associated with a reduction in VTE incidence. (unav.edu)
Recent randomized controlled trials (RCTs) have assessed the role of vagus nerve stimulation (VNS) when paired with standard rehabilitation in stroke patients. (karger.com)
So it's difficult to draw conclusions about patients who don't fit those metrics. (medscape.com)
World Health Organization (WHO), are often selected on and hospitalizations may reduce when cardiovascular the basis of disease prevalence, evidence for efficacy and patients use lifelong medication consistently (9) . (who.int)

We also plan to update our conclusions when the findings of the Salt Substitute and Stroke Study are published. (givewell.org)
The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study. (mja.com.au)
These findings add to the evidence of road-traffic noise as a cardiovascular risk factor. (lu.se)
Previous studies have reached conflicting conclusions on this issue, some supporting our findings and others not. (natap.org)
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)

In combination, these tobacco control interventions could avert 25% of myocardial infarctions and strokes (95% CI: 17%-34%) if the effects of the interventions are additive. (who.int)

IMPORTANCE: The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC). (healthpartners.com)

Manual tracing IMT (mt-IMT) and edge-detected IMT (ed-IMT) measurements of the far wall of the common carotid artery served as outcome variables for multivariable linear regression models using Framingham cardiovascular risk factors and ethnicity as independent predictors. (duke.edu)

Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? (mja.com.au)
To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors. (mja.com.au)
Crude CHD, ischaemic stroke, and total mortality rates were higher in the presence of MetS in men and women. (mja.com.au)
In proportional hazards models that included conventional risk factors, but excluded variables used to define the presence of MetS, MetS was a significant predictor of CHD, stroke and total mortality. (mja.com.au)

Considering the limitation of studies investigating the relationship between T. gondii and cardiovascular biomarkers, this study was focused on assessing the association of T. gondii to nine cardiovascular biomarkers. (mdpi.com)

Is my rate of heart failure readmissions artery bypass graft (CABG) surgery, pneumonia and acute stroke). (who.int)

0.04) remained in the model as independent predictors of LVM. (scienceopen.com)

Investigators noted that the ceramide-phospholipid risk score was comparable and synergistic predictive performance compared with previously published CVD risk models for secondary prevention. (hcplive.com)
OBJECTIVE: To provide updated model-based estimates of the net balance in benefits and harms from routine use of low-dose aspirin for primary prevention. (healthpartners.com)
CONCLUSIONS AND RELEVANCE: This microsimulation study suggested that several population groups may benefit from taking aspirin for the primary prevention of CVD, primarily in persons starting at younger ages with higher 10-year CVD risk. (healthpartners.com)
Thus, our efforts should be concentrated not only on cardiovascular disease treatment and prevention, but also on health promotion and primordial prevention. (revespcardiol.org)
For better prevention and intervention, relevant guidelines recommend using predictive models for early detection of ASCVD high-risk groups. (biomedcentral.com)
Avoidance of overweight from adolescence onwards is likely important for cardiovascular disease prevention. (nature.com)

Conclusions Smoke-free laws and substantially increased tobacco taxation appear to be markedly potent population measures to avert future cardiovascular deaths in India. (who.int)

The OR of cerebrovascular disease were lower in bus company employees than in the general workers after adjusting the covariates, but similar in the propensity score matched model. (biomedcentral.com)
We used a dietary model of cerebrovascular disease that relies on the induction of hyperhomocysteinemia (HHcy). (biomedcentral.com)

1 Inflammation plays an important role in the pathogenesis of atherosclerosis, and markers of low grade inflammation have been consistently associated with a higher risk of cardiovascular disease. (bmj.com)

The Framingham risk score was predictive of stroke, myocardial infarction, and angina among a nationally representative sample of adults in South Korea. (cdc.gov)
Traditional ASCVD prediction models (Framingham and China-PAR models) were constructed in the test set. (biomedcentral.com)

Based on this, we estimated the 10-year time-weighted mean noise exposure for 3.6 million Danes aged >35 years, of whom 184 523 developed incident stroke during follow-up from 2000 to 2017. (lu.se)
Because exposure to cardiovascular risk factors occurs from early ages, this strategy must be expanded and adjusted throughout the life of an individual. (revespcardiol.org)
Passive smoking is strongly associated with an increased risk of stroke, and this increased risk is disproportionately high at low levels of exposure. (wikipedia.org)
MEASUREMENTS AND MAIN RESULTS: Air pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases following a standardized procedure within the ESCAPE study. (surrey.ac.uk)
CONCLUSIONS: In this study of 16 cohorts, there was no association between air pollution exposure and nonmalignant respiratory mortality. (surrey.ac.uk)

Significant hazard ratios were attenuated when adjusted according to model 2. (springer.com)
There were 34 post randomization strokes in the proactive arm and 35 in the reactive arm (hazard ratio (95% confidence interval): 0.90 (0.56, 1.44), p=0.66). (gla.ac.uk)
The Cox proportional hazard models were introduced to investigate the association between total physical activity and CVDs, reporting as hazard ratios (HR) and 95% confidence intervals (CIs). (biomedcentral.com)

As a former Senior Vice President for Science and Quality at the American College of Cardiology, Dr. Wright oversaw the development of guidelines, performance measures and appropriate use criteria to include the National Cardiovascular Data Registry. (cdc.gov)

Background We simulated tobacco control and pharmacological strategies for preventing cardiovascular deaths in India, the country that is expected to experience more cardiovascular deaths than any other over the next decade. (who.int)
According to the model's results, smoke-free legislation and tobacco taxation would likely be the most effective strategy among a menu of tobacco control strategies (including, as well, brief cessation advice by health care providers, mass media campaigns, and an advertising ban) for reducing myocardial infarction and stroke deaths over the next decade, while cessation advice would be expected to be the least effective strategy at the population level. (who.int)
nevertheless, the impacts of tobacco control policies and pharmacological interventions appear to be markedly synergistic, averting up to one-third of deaths from myocardial infarction and stroke among 20- to 79-y-olds over the next 10 y. (who.int)
In individuals with chronic kidney disease, additional deaths from cardiovascular disease related to hyperkalaemia from increased intake of potassium were calculated. (bmj.com)
The net effects on deaths from cardiovascular disease were estimated as the difference and ratio of averted and additional deaths from cardiovascular disease. (bmj.com)
The net effect would be about 450 000 (183 699 to 697 084) fewer deaths annually from cardiovascular disease in the overall population and 21 000 (1928 to 42 926) fewer deaths in individuals with chronic kidney disease. (bmj.com)
Conclusions Nationwide potassium enriched salt substitution in China was estimated to result in a substantial net benefit, preventing around one in nine deaths from cardiovascular disease overall. (bmj.com)
The number of deaths was 46,341 for any cause, 12,621 for cardiovascular disease (CVD), 6202 for ischemic heart disease (IHD), and 2894 for stroke. (coffeeandhealth.org)

We modeled the impacts of 5 hypothetical therapies affecting different patient types: curative gene therapy for a childhood disorder, highly effective hepatitis C virus therapy, disease-modifying Alzheimer disease therapy, and cardiovascular disease therapy for both rare genetic and higher-risk prior cardiovascular event populations. (ajmc.com)

In 2019, Discovery Health published a risk adjustment model to determine standardised mortality rates across South African private hospital systems, with the aim of contributing towards quality improvement in the private healthcare sector. (who.int)

For instance, the 10-year cardiovascular death risk of a CHD patient may vary from 5% to over 20%," said Reijo Laaksonen, MD, PhD, chief medical officer for Zora Biosciences. (hcplive.com)

The aim of this study was to investigate whether the coffee brewing method is associated with any death and cardiovascular mortality, beyond the contribution from major cardiovascular risk factors. (coffeeandhealth.org)
Table 1 Major cardiovascular risk models and their inputs and outputs. (biomedcentral.com)

Randomized controlled trials have shown that lowering blood pressure significantly reduces cardiovascular disease (2). (cdc.gov)

Currently, the most commonly used survival analysis method is the Cox proportional hazards model, and most traditional ASCVD prediction models are constructed based on this model. (biomedcentral.com)
Factors associated with ASCVD were identified using cause-specific Cox proportional hazards models. (natap.org)

Cardiovascular disease remains one of the greatest causes of disease and mortality worldwide. (lu.se)

Anatomy10

Diseases56

Chemicals and Drugs9

Analytical, Diagnostic and Therapeutic Techniques and Equipment67

Psychiatry and Psychology6

Phenomena and Processes15

Disciplines and Occupations4

Anthropology, Education, Sociology and Social Phenomena6

Technology, Industry, Agriculture1

Information Science7

Named Groups3

Health Care56

Geographicals6

Diseases23

Coronary24

Atherosclerotic cardiovascular disease5

Morbidity7

Outcomes13

Hypertension7

Clinical12

Ischemic stroke4

Risks7

Renal4

Complications7

Cohort7

Adverse3

Hemorrhagic3

Events18

Associated with cardiovascular disease2

Epidemiology1

Traditional cardiovascular risk factors1

Obesity6

Heart attacks4

Methods2

Analyses6

Patients17

Findings5

Myocardial infarctions1

Colorectal Cancer1

Multivariable1

Total mortality4

Biomarkers1

Acute1

Predictors1

Prevention6

Future cardiovascular1

Cerebrovascular disease2

Atherosclerosis1

Framingham2

Exposure5

Hazard3

American College of1

Deaths8

Populations1

20191

Year cardiovascular1

Major cardiovascular2

Reduces cardiovascular1

Proportional2

Disease and mortality1