Strict host specificity. Medical search. Frequent questions

To investigate species-specificity and potential for cross species transmission of HBV between sympatric species of apes (such as gorillas and chimpanzees in Central Africa) or between humans and chimpanzees or gorillas, variants of HBV infecting captive wild-born non-human primates were genetically characterised. (ox.ac.uk)
Synaptic Systems offers a panel of nanobody based secondary reagents that provide excellent species specificity. (sysy.com)

Journal Article] Molecular mechanism of strict substrate specificity of an Extradiol Dioxygenase, DesB, derived from Sphingobium sp. (nii.ac.jp)

Laboulbeniomycetes is a class of fungi that have obligate associations with arthropod hosts, either for dispersal (order Pyxidiophorales) or as biotrophic parasites (orders Herpomycetales and Laboulbeniales). (researchportal.be)
With this study, we contribute to the knowledge of the geographical distribution and host specificity of Laboulbeniales fungi associated with ectoparasitic bat flies within Europe. (biomedcentral.com)

Sequence analysis of the gp60 gene has been used in studies of the genetic diversity, host adaptation, infection sources, and transmission dynamics of these Cryptosporidium spp. (cdc.gov)
We propose that the opportunity for genetic mixing during part of the host-symbiont life cycle is the key to evade drift-induced genome erosion. (frontiersin.org)
Furthermore, we suggest the earthworm- Verminephrobacter association as a new experimental system for investigating host-microbe interactions, and especially for understanding genome evolution of vertically transmitted symbionts in the presence of genetic mixing. (frontiersin.org)

Molecular characterizations of the microsporidian pathogen Enterocytozoon bieneusi on the ribosomal inside transcribed spacer (ITS) locus have recognized almost 500 genotypes in 11 phylogenetic teams with completely different host ranges. (iowaodes.com)
Both of these observations provide evidence for circulation of HBV between different species and sub-species of non-human primates, a conclusion that differs from the hypothesis if of strict host specificity of HBV genotypes. (ox.ac.uk)

MetaRon consistently achieved high operon prediction sensitivity, specificity and accuracy across E. coli whole-genome (97.8, 94.1 and 92.4%), simulated genome (93.7, 75.5 and 88.1%) and E. coli c20 (87, 91 and 88%,), respectively. (biomedcentral.com)
however, a demonstrated fourfold rise between acute and convalescent samples has much higher sensitivity and specificity than a single elevated, convalescent titer. (medscape.com)

We discuss parasite prevalence and host specificity in the light of our findings and the available literature. (biomedcentral.com)

10.1016/j.str.2023.05.013. (le.ac.uk)
doi: 10.1016/j.str.2017.11.004. (uni-wuerzburg.de)

This is one of the basis that supports the hypothesis that persistent bacterial attacks, associated with irregular host inflammatory response, may have consequences beyond the periodontal tissues and may even influence the occurrence of some systemic diseases (2,3). (bvsalud.org)

identified by molecular diagnostic tools, it infects the greatest variety of host species ( 12 ). (cdc.gov)

Overall, our results suggest that viruses may have evolved their miRNA repertoire to target specific host pathways as a means for their survival. (biomedcentral.com)

Little is known, however, about the mechanism by which the propeptide of FhCL3, a cathepsin L peptidase secreted by the infective newly excysted juveniles (NEJs), regulates the inhibition and activation of the mature enzyme before it is secreted into host tissues. (biomedcentral.com)

This co-evolution of commensal/mutualistic microbes within marine vertebrate hosts may have had a strong contribution to their nutritional adaptation to specific diets [ 10 ]. (springer.com)
Coccidiosis is a widespread disease reported in numerous vertebrate that is caused by Eimeria species and shows strict host specificity [ 1 ]. (biomedcentral.com)
Plasmodium parasites are highly specific with humans being the only vertebrate host and Anopheles mosquitoes the vectors. (ispub.com)
Cryptosporidia are obligate, intracellular coccidian protozoa that replicate in small-bowel epithelial cells of a vertebrate host. (msdmanuals.com)
When the infective oocysts are ingested by humans or another vertebrate host, the cycle begins again. (msdmanuals.com)

Humans are the only hosts of the organism and is present in the upper respiratory tract. (who.int)

The symbionts have a beneficial effect on host reproduction and likely live on their host's waste products. (frontiersin.org)
We hypothesize that taxa with haustoria, rhizoidal structures that make contact with the host's body cavity, have very strict host specificity. (researchportal.be)

As a result, a trained medical professional must administer the biologic and strict adherence to aseptic manufacturing and packing must be practiced. (abiteccorp.com)
You will be confronted with a host of them that demand strict adherence. (cwhkcpa.com)

Bovine viral diarrhea virus does not possess strict host-specificity and infections have been demonstrated in over 50 species in the mammalian order Artiodactyla. (auburn.edu)
The parasite has the widest latitudinal and longitudinal distribution of any worm parasite, largely because of its ability to infect and complete its life cycle in a wide range of mammalian hosts. (biomedcentral.com)

N-GPV and cGPV infections can be distinguished based on host specificity. (biomedcentral.com)
Although generally asymptomatic in immunocompetent hosts, HCMV illness is definitely a major cause of morbidity and mortality in immunocompromised individuals, such as babies following congenital or neonatal infections, transplant recipients, or AIDS individuals [2]. (accessibletech4all.org)

Starting from its application on whole-genome to simulated mixture of three whole-genomes ( E. coli MG1655, Mycobacterium tuberculosis H37Rv and Bacillus subtilis str. (biomedcentral.com)
Unlike E. coli or Enteroccoccci , host-specific strains of Bacteroides and Lachnospiraceae exist. (kennesaw.edu)

Model systems where the symbiotic partners can be cultured and manipulated separately, e.g., the symbiosis between squids and their bioluminescent symbionts, Vibrio fischeri , are highly valuable when examining function, specificity, and host-microbe interactions during initiation or persistence of the symbiosis ( Ruby, 2008 ). (frontiersin.org)
The beneficial earthworm- Verminephrobacter symbiosis is a promising emerging experimental system for investigating host-microbe interactions: first, earthworms are readily collected in the wild and easily maintained in the lab. (frontiersin.org)
These results indicate that I-J is an isomorphic structure adaptively expressed on Th cells that is involved in the unidirectional regulatory cell interactions, and that the polymorphism cannot be explained merely by the restriction specificity of the conventional T cell receptor heterodimer. (silverchair.com)
Figure 1 depicts all possible miRNA-mediated interactions between a virus and the host. (biomedcentral.com)

Regional specificities no doubt add to the burden of compliance. (cwhkcpa.com)
They include data encryption, strong user authentication and authorization mechanisms with robust access controls, and compliance with strict data protection laws and government regulations. (opigno.org)
Pexip's Private Cloud "gives customers the ease and scalability of a shared cloud with the control, security and privacy of a self-hosted solution, mission critical to industries with strict regulatory compliance including finance, healthcare and government services. (futurumgroup.com)
One of the most interesting and handy particularities of Pexip's Private Cloud is that it allows customers to choose in which region and country its data will be hosted, giving organizations more control over their data, especially in countries where security concerns and/or compliance rules may inform the geographic specificity of their data storage needs. (futurumgroup.com)
It will also provide organizations in industries with strict regulatory compliance regimes (finance, healthcare, and government services) a greater range of data security and privacy options to facilitate compliance. (futurumgroup.com)

Consequently, their geographical and host distributions are strongly influenced by those of their hosts. (mdpi.com)

DNA viruses have utilized several mechanisms to evade host defenses [ 11 ]. (biomedcentral.com)
This review explores the composition, function and adaptive mechanisms of the vaginal microbiome in health and those disease states in which there is a breach in the host-microbial relationship. (frontiersin.org)
Probiotics are commensal or nonpathogenic microbes that confer beneficial effects on the host through several mechanisms such as competitive exclusion, antibacterial effects, and modulation of immune responses. (hindawi.com)

Mold is a greater hazard for persons with conditions such as impaired host defenses or mold allergies. (cdc.gov)

The vagina also harbors numerous microorganisms (the "microbiota"), that exist (in conjunction with their genes and products) in a regulated mutualistic relationship with the host (the "microbiome") ( 4 ). (frontiersin.org)

Here we show that for several of the 135 known viral miRNAs in human viruses, the human genes targeted by the viral miRNA are enriched for specific host pathways whose targeting is likely beneficial to the virus. (biomedcentral.com)
Finally, there are several known instances of viral miRNAs targeting host genes (Figure 1d ). (biomedcentral.com)
This study suggested that the number of viral miRNA targets in the host may be much greater than previously assumed and are specific to host pathways. (biomedcentral.com)
b) Host miRNAs target viral genes. (biomedcentral.com)
They have co-evolved with their host over millions of years and have had to adapt to the cellular environment, which in turn is evolving to evade viral infection. (biomedcentral.com)

The current supremacy of biologics lies in their high specificity towards one target, whereas small molecules can unintentionally bind to multiple targets. (abiteccorp.com)
Propeptides bind to their cognate enzyme with high specificity. (biomedcentral.com)

These findings are most consistent with frequent host-switching by the pollinators, leading to fig hybridization, even between distantly related clades. (nature.com)
While the audience groups, objectives, policies, and the needs of governmental training can differ vastly, the solution must meet a number of strict requirements consistent across the countries. (opigno.org)

There are known instances of viruses using their endogenous miRNAs to target their own genes to evade host immune system's surveillance and maintain latency (Figure 1c ) [ 8 ]. (biomedcentral.com)

Both bacterial groups cannot survive long periods outside of their hosts and are considered a good indicator of recent fecal contamination in environmental waters. (kennesaw.edu)

C. ubiquitum is of public health concern because of its wide geographic distribution and broad host range. (cdc.gov)
For taxa without haustoria, the micro-habitat-as selected by the host-governs host shifting, presence or absence of the fungus, abundance, effective host range, and geographic distribution. (researchportal.be)

The reactivity of the antiserum is directed to the Fc subunit of the IgA molecule which expresses strict isotypic (class) specificity. (fishersci.com)
Although above results suggested that I-J is the structure reflecting the inducible MHC restriction specificity, further studies revealed some interesting controversies: First, the I-J phenotype did not always correlate with the class II restriction specificity, e.g. (silverchair.com)

Viruses also encode miRNAs and there is evidence to suggest that virus-encoded miRNAs target specific host genes and pathways that may be beneficial for their infectivity and/or proliferation. (biomedcentral.com)
a) Endogenous host miRNAs target specific host genes. (biomedcentral.com)

In its own words, Pexip's Private Cloud offering is designed to "give customers the ease and scalability of a shared cloud with the control, security and privacy of a self-hosted solution. (futurumgroup.com)
In essence, Pexip's Private Cloud combines the same degree of data control and transparency already provided by its self-hosted deployment option, but with the ease and scalability of a SaaS solution: Under this type of private cloud deployment, conference management is hosted by the customer, but the compute power needed to manage call capacity is handled on the Pexip side in a secure, private customer-dedicated environment. (futurumgroup.com)

Yet, if and how the tissue environment shapes the antigen specificity of iNKT cells remains unknown. (elifesciences.org)
This strict linkage between the restriction specificity and I-J phenotype was also found on Th cells developed in bone marrow chimera constructed with intra-H-2-recombinant mice. (silverchair.com)

While traditional fecal coliform enumeration can give a general measure of contamination, the specificity imparted by modern MST provides a more informative assessment of contaminants and their likelihood to affect human health outcomes. (kennesaw.edu)
The modern baby shower has no strict rules: You can invite whoever the expectant family wants to be included. (paperlesspost.com)

This can be attributed to their inability to proliferate outside of their hosts, resulting in a close relationship by which they evolve into species-specific strains. (kennesaw.edu)

Penicillidia conspicua is unambiguously the main host species for A. nycteribiae based on our and previous findings. (biomedcentral.com)

Most anatomical compartments, including mucosal surfaces and solid organs, host large populations of tissue-resident lymphocytes which are uniquely placed to provide local networks for immune surveillance and defence against infection ( Fan and Rudensky, 2016 ). (elifesciences.org)
Periodontal disease is responsible for a host immune-inflammatory response, contributing towards clarifying its association with cardiovascular disease. (bvsalud.org)

Coccidiosis disease control efforts have been focused on the development of several anticoccidials (ionophores and synthetic chemicals) that have been mainly directed to the parasites during the sexual and asexual stages that occur within the host rather than targeting the most infectious stage, the oocyst [ 13 ]. (biomedcentral.com)
The distribution of parasites is shaped by the distribution of their hosts, although complete overlaps are infrequent. (biomedcentral.com)
Miniopterus schreibersii hosts a myriad of highly specific parasites as for example Spinturnix psi mites (Acari: Mesostigmata: Spinturnicidae), Nycteribia schmidlii and Penicillidia conspicua bat flies (Diptera: Hippoboscoidea: Nycteribiidae), or Polychromophilus melanipherus blood parasites (Alveolata: Apicomplexa: Plasmodiidae) [ 9 , 11 , 12 ]. (biomedcentral.com)
Even though these non-specific associations are considered the result of accidental host choice by the parasites, they cannot be considered rare [ 9 ]. (biomedcentral.com)

In this regard, the proposed research project studied "right to the city", housing and privacy of displaced people of second NK war during and after the 44-day war and to what extent capital city Yerevan was and is ready to host those forcibly displaced persons (FDPs) as an urban space. (lu.se)

An optimal host-microbial interaction is required for the maintenance of eubiosis and vaginal health. (frontiersin.org)

Co-evolutionary analysis of phthirapterans and their hosts regularly show that the supposed impediments to host switching and the evolution of host generalists have been overestimated, and this has been confirmed in transfer experiments and through morphological studies. (mdpi.com)

Infection of the host is dependent on the secretion of a specific set of these peptidases. (biomedcentral.com)
To this end, we have been developing Bacteroides - and Lachnospiraceae-based species-specific assays that identify the presence of gene sequences uniquely found in these bacteria that are associated with their corresponding host species. (kennesaw.edu)

He appreciated the honour bestowed on Mozambique for hosting the fifty-fifth session of the Regional Committee. (who.int)
In addition, this year the WHO Regional Office for Africa hosted a regional consultation on social determinants of health in Brazzaville. (who.int)
He further expressed his gratitude to the government and people of Mozambique for hosting the fifty-fifth session of the WHO Regional Committee for Africa. (who.int)

Pexip's Private Cloud aims to provide organizations with the security and geographic specificity of on-premise solutions, but the agility, speed, ease of use, and scale of a public cloud. (futurumgroup.com)

We all know the iconic five-ring emblem that symbolizes the union of international athletes, but each host city gets the opportunity to create its own unique logo. (bluetext.com)

Lassa fe- Lassa virus in many more districts and states in en- ver is endemic in West Africa and has been reported demic countries of the West African sub-region and from Sierra Leone, Guinea, Liberia, and Nigeria4-7. (folkhalsomyndigheten.se)

allowing important aspects of specificity and initiation of the symbiosis to be explored. (frontiersin.org)
Athens Digital Arts Festival aims to encourage and promote all aspects of digital creativity by hosting local as well as international artists and communities. (adaf.gr)

The physiological status of the vaginal milieu is important for the wellbeing of the host as well as for successful reproduction. (frontiersin.org)

However, this view has been challenged in recent decades, to the point where the traditional assumption of strict co-speciation and strict host specificity can no longer be maintained. (mdpi.com)
Despite its minimalism, this logo manages to acknowledge the host country, the traditional Olympic identity, and the moral foundation of the Games. (bluetext.com)

When nymphal ticks feed, the bacteria pass through the hemocoel to the salivary glands and are transmitted to a new host in the saliva after 2 days. (cdc.gov)

Olympic logos of the past have varied widely in color, type, and style, and each new logo is put to the test to tell a story not only about an Olympic season but about the host country itself. (bluetext.com)

Host associations have traditionally been seen as the predominant factor influencing taxon limits and relationships in lice. (mdpi.com)

Above all, the older view of the role of host switching has been found to be overly conservative and restrictive. (mdpi.com)
Realization of the right to partic- ipate, as well as space consumption are seen as part of the FDPs integration process in the hosting environment, where both the social networks and the institutions play a vital role in the process of social integration. (lu.se)

They are strict anaerobes found in large quantities in the intestines of animals. (kennesaw.edu)

Since iNKT cell activation can prevent or promote immunopathology in diverse disease contexts, the strict control of peripheral iNKT cell homeostasis is vital to regulate local immunity. (elifesciences.org)

Anatomy2

Organisms32

Diseases3

Chemicals and Drugs20

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes46

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science4

Health Care8

Species Specificity2

Substrate1

Fungi2

Genetic3

Genotypes2

Sensitivity2

Prevalence1

10.10162

Hypothesis1

Molecular1

Repertoire1

Mechanism1

Vertebrate5

Humans1

Host's2

Adherence2

Mammalian2

Infections2

Coli2

Interactions4

Compliance5

Geographical1

Mechanisms3

Defenses1

Mutualistic1

Viral5

High2

Consistent2

Evade1

Bacterial1

Geographic distribution2

Class2

Genes2

Scalability2

Cells2

Modern2

Evolve1

Findings1

Immune2

Parasites4

Research1

Interaction1

Studies1

Specific2

Regional3

Provide1

Unique1

Virus1

Aspects2

Important1

Traditional2

Bacteria1

Country1

Associations1

Role2

Found1

Cell1