• Stress Myocardial Perfusion SPECT in Women: Is It the Cornerstone of the Noninvasive Evaluation? (snmjournals.org)
  • Brain perfusion single photon emission computed tomography (SPECT) neuroimaging reveals visual correlates of brain function. (frontiersin.org)
  • These findings support two distinct patterns of SPECT perfusion scan changes that can be found in individuals with bipolar disorder. (frontiersin.org)
  • While preliminary, the findings in this cohort support the need for larger, diverse cohort studies of bipolar and control subjects to assess the predictive value of these particular SPECT perfusion findings in bipolar disorder. (frontiersin.org)
  • The 2.5-mA CT commonly used for this purpose in myocardial perfusion SPECT is generally considered "nondiagnostic" in quality. (snmjournals.org)
  • Two hundred consecutive patients who underwent clinical low-amperage-CT attenuation-corrected myocardial perfusion studies acquired on a SPECT/CT system were included in the study. (snmjournals.org)
  • Myocardial perfusion SPECT is a well-established clinical tool that provides diagnostic and prognostic information about coronary artery disease. (snmjournals.org)
  • Attenuation correction is now recommended to improve the diagnostic accuracy of myocardial perfusion SPECT ( 1 ). (snmjournals.org)
  • At present, the low-amperage-CT component of myocardial perfusion SPECT/CT is used almost exclusively for attenuation correction, and only recently have recommendations to review the attenuation maps for quality control purposes been published ( 1 ). (snmjournals.org)
  • SPECT at rest and stress was performed according to standard clinical protocols for myocardial perfusion imaging. (snmjournals.org)
  • A myocardial perfusion SPECT (single photon emission computed tomography) test is a procedure that demonstrates the function of the myocardium. (medscape.com)
  • Objectives: To determine the incidence and characteristics of myocardial perfusion abnormalities in patients with ST depression in recovery only, using Tc-99m gated-SPECT. (uanl.mx)
  • Investigators reported results of CORE320 at ESC 2012 and found that combined CTA and CTP was capable of detecting hemodynamically significant stenoses (50% or 70%), as defined by invasive angiography with an associated SPECT perfusion defect. (acc.org)
  • The combination of CTA and CTP had similar diagnostic power to the combination of ICA and SPECT myocardial perfusion imaging (MPI) in identifying revascularized patients at 30 days (p = 0.13). (acc.org)
  • Images for CTA, computed tomography perfusion (CTP), and single-photon emission computed tomography (SPECT) were each read by 2 independent blinded readers. (wustl.edu)
  • CONCLUSIONS: Adenosine stress CT can identify stress-induced myocardial perfusion defects with diagnostic accuracy comparable to SPECT, with similar radiation dose and with the advantage of providing information on coronary stenosis. (wustl.edu)
  • Prognostic significance of ischemia location on stress myocardial perfusion SPECT: Tracing the fingerprints of the widow maker. (nih.gov)
  • The aim of this study was to determine if patients with suspected MVA have lower global myocardial perfusion (global MP) during adenosine stress compared with healthy controls and coronary artery disease (CAD) patients and to determine if there are sex differences in global MP. (lu.se)
  • Methods: Twenty-three patients with suspected MVA (66 ± 11 years), 19 CAD patients (69 ± 5 years) with stress-induced ischaemia and 24 healthy controls (61 ± 10 years) underwent cardiac magnetic resonance (CMR) including coronary sinus flow measurements and first-pass perfusion at rest and during adenosine stress. (lu.se)
  • Methods: We studied 1,386 patients with known or suspected coronary artery disease by means of stress 99mTc-tetrofosmin myocardial perfusion tomography. (eur.nl)
  • What determines coronary perfusion? (onteenstoday.com)
  • When anaesthetising patients with coronary artery disease, maintain coronary perfusion pressure and avoid tachycardia. (onteenstoday.com)
  • How do you get coronary perfusion pressure? (onteenstoday.com)
  • 5. In the absence of coronary stenosis and myocardial hypertrophy, coronary blood flow increases proportionally as diastolic perfusion time decreases during stress tests. (onteenstoday.com)
  • How does heart rate influence coronary artery perfusion? (onteenstoday.com)
  • Myocardial perfusion scans help us diagnose: Coronary artery disease. (onteenstoday.com)
  • How would heart rate influence coronary artery perfusion and myocardial oxygen delivery? (onteenstoday.com)
  • What is normal coronary perfusion pressure? (onteenstoday.com)
  • Studies in adult patients report a normal coronary perfusion pressure of 60-80 mmHg. (onteenstoday.com)
  • A recent retrospective study in adults reported a coronary perfusion pressure of 45 mmHg in survivors of cardiogenic shock. (onteenstoday.com)
  • We assessed the incremental prognostic value of heart rate reserve (HRR) over stress myocardial perfusion single-photon emission computed tomography (MPS) findings in patients with suspected coronary artery disease (CAD). (unina.it)
  • A heart perfusion imaging scan can also evaluate the effectiveness of certain cardiac treatments, such as coronary artery stenting or bypass surgery . (medicalnewstoday.com)
  • This study aims to investigate the use of myocardial perfusion scintigraphy (MPS) for advanced assessment of patients with known or suspected coronary artery disease, cardiovascular disease, and in the intermediate risk group for SD. (comu.edu.tr)
  • Another method of indirectly detecting coronary artery disease is to perform echocardiography while the heart is undergoing exercise or pharmacologically induced stress. (medscape.com)
  • CORE320 is the acronym for a study designed by investigators at Johns Hopkins University, Baltimore, Maryland: the combined coronary atherosclerosis and myocardial perfusion evaluation using 320-row detector CT. (acc.org)
  • Overall, he said, "We found the addition of CT myocardial perfusion to CT angiography allows clinicians to distinguish between anatomic and flow limiting stenoses in patients with suspected coronary disease. (acc.org)
  • While coronary autoregulation maintains resting myocardial blood flow (MBF) constant over a wide range of pathological conditions, MBF reserve during hyperaemic stress is impaired in several common disease processes. (biomedcentral.com)
  • OBJECTIVES: This study sought to determine the feasibility of performing a comprehensive cardiac computed tomographic (CT) examination incorporating stress and rest myocardial perfusion imaging together with coronary computed tomography angiography (CTA). (wustl.edu)
  • BACKGROUND: Although cardiac CT can identify coronary stenosis, very little data exist on the ability to detect stress-induced myocardial perfusion defects in humans. (wustl.edu)
  • In theory, use of these stress agents in the CMR environment might be more risky due to the reduced robustness of ECG monitoring and the need for remote resuscitation in case of emergency, especially for patients with high likelihood of significant coronary artery disease (CAD). (biomedcentral.com)
  • A: A cardiac CT stress perfusion study should be reported using CPT code 75574 (Computed tomographic angiography, heart, coronary arteries and bypass grafts (when present), with contrast material, including 3D image post-processing (including evaluation of cardiac structure and morphology, assessment of cardiac function, and evaluation of venous structures, if performed) and one of the appropriate cardiac stress test codes (93015-93018). (acr.org)
  • A population of 135 patients who had undergone both myocardial technetium-99m-sestamibi rest-stress scintigraphy and coronary angiography within 3 months was studied. (lu.se)
  • Because coronary artery plaques that are not significantly stenotic (ie, do not result in ischemia during stress testing) may nonetheless rupture and cause an acute coronary syndrome, a normal stress test result does not guarantee future freedom from myocardial infarction. (msdmanuals.com)
  • Development and evaluation of a radiomics model of resting N-ammonia positron emission tomography myocardial perfusion imaging to predict coronary artery stenosis in patients with suspected coronary heart disease. (cdc.gov)
  • The ImPRESS project main objective is to develop a novel imaging paradigm coined Restricted Perfusion Imaging (RPI) to reveal - for the first time in humans - vascular restrictions in solid cancers caused by mechanical solid stress, and use RPI to demonstrate that alleviating this force will repair the cancerous microenvironment and improve therapeutic response. (europa.eu)
  • and (III) there are no available imaging technologies for medical diagnostics of solid stress in human cancers. (europa.eu)
  • Purpose: The aim of this study was to ascertain whether stress myocardial perfusion imaging can independently predict long-term mortality. (eur.nl)
  • QUALITATIVE: There is a medium size severe reversible perfusion defect mid inferior wall to apex which persisted on prone stress imaging. (medhelp.org)
  • Nuclear stress myocardial perfusion imaging (MPI) is a nuclear cardiology test that shows how well blood flows to the muscle of the heart (myocardium). (ottawaheart.ca)
  • Objectives: The aim of this study was to investigate the prognostic value of stress cardiac magnetic resonance imaging (CMR) in patients with reduced left ventricular (LV) systolic function. (uky.edu)
  • Vasodilator stress agents for myocardial perfusion imaging. (qxmd.com)
  • A heart perfusion imaging scan, or myocardial perfusion scan, is a test that tells doctors how well a person's heart pumps blood. (medicalnewstoday.com)
  • A heart perfusion imaging scan is a noninvasive diagnostic procedure to assess blood flow to the heart muscle. (medicalnewstoday.com)
  • If a person experiences chest pain , especially during physical activity or times of stress, doctors may recommend a heart perfusion imaging scan to understand the reason for the pain. (medicalnewstoday.com)
  • A heart perfusion imaging scan can help doctors understand whether chest pain is due to CAD or another cause. (medicalnewstoday.com)
  • Doctors may use a heart perfusion imaging scan to determine whether ischemia is causing this reduced heart strength. (medicalnewstoday.com)
  • Most people will not experience problems or complications following a heart perfusion imaging scan. (medicalnewstoday.com)
  • Some people may require a stress scan, in which doctors use the imaging test to evaluate blood flow to the heart during exercise, such as when walking on a treadmill. (medicalnewstoday.com)
  • People should follow the specific instructions given by their doctor before a heart perfusion imaging scan. (medicalnewstoday.com)
  • The HBP change of the mice was detected by laser speckle perfusion imaging (LSPI) before and after being given interventions, and the NO in liver tissue was detected by nitric acid reductase in each group. (hindawi.com)
  • The term perfusion scanning encompasses a wide range of medical imaging modalities. (wikipedia.org)
  • Microspheres CT MRI Nuclear medicine or NM Using radioactive microspheres is an older method of measuring perfusion than the more recent imaging techniques. (wikipedia.org)
  • The method by which perfusion to an organ measured by CT is still a relatively new concept, although the first dynamic imaging studies of cerebral perfusion were reported on in 1979 by E. Ralph Heinz et al. (wikipedia.org)
  • There are different techniques of Perfusion MRI, the most common being dynamic contrast-enhanced (DCE), dynamic susceptibility contrast imaging (DSC), and arterial spin labelling (ASL). (wikipedia.org)
  • Arterial spin labelling (ASL) has the advantage of not relying on an injected contrast agent, instead inferring perfusion from a drop in signal observed in the imaging slice arising from inflowing spins (outside the imaging slice) having been selectively saturated. (wikipedia.org)
  • Invasive angiography and CT angiography are limited in delineating flow-limiting lesions that can be detected, however, by perfusion imaging or invasive FFR. (acc.org)
  • There has been limited evidence regarding CT perfusion imaging (CTP) and most of what exists was performed using 64-row multidetector computed tomography (MDCT) systems. (acc.org)
  • Adenosine-induced stress myocardial perfusion imaging using dual-source cardiac computed tomography. (wustl.edu)
  • Cardiac magnetic resonance (CMR) stress perfusion imaging with either adenosine or dipyridamole is increasingly used both in clinical and research practice. (biomedcentral.com)
  • In a large series, the use of intravenous adenosine in CMR perfusion imaging is safe and well tolerated in patients with even severe CAD. (biomedcentral.com)
  • The total volume of contrast given for stress and rest imaging (if performed) and the stress test agent should be reported as well. (acr.org)
  • If rest perfusion imaging is performed in addition to stress perfusion imaging, it is not appropriate to report a second cardiac CT study code. (acr.org)
  • Clinicians should avoid using the imaging agents regadenoson ( Lexiscan , Astellas Pharma US) and adenosine ( Adenoscan , Astellas Pharma US) for cardiac nuclear stress tests of patients with signs or symptoms of unstable angina or cardiovascular instability because the drugs may increase their risk for a fatal heart attack, the US Food and Drug Administration (FDA) announced today. (medscape.com)
  • The agency approved adenosine in 1995 and regadenoson in 2008 for radionuclide myocardial perfusion imaging in patients who cannot undergo exercise stress testing. (medscape.com)
  • Myocardial Perfusion Imaging Radionuclide imaging uses a special detector (gamma camera) to create an image following injection of radioactive material. (msdmanuals.com)
  • Deep learning applications in myocardial perfusion imaging, a systematic review and meta-analysis. (cdc.gov)
  • Q: What Is (Are) the Appropriate CPT Code(s) to Report a Cardiac CT Stress Perfusion Study? (acr.org)
  • [11-20-2013] The U.S. Food and Drug Administration (FDA) is warning health care professionals of the rare but serious risk of heart attack and death with use of the cardiac nuclear stress test agents Lexiscan (regadenoson) and Adenoscan (adenosine). (fda.gov)
  • Lexiscan and Adenoscan are FDA approved for use during cardiac nuclear stress tests in patients who cannot exercise adequately. (fda.gov)
  • Lexiscan or Adenoscan are administered by intravenous injection during a cardiac nuclear stress test to patients who cannot adequately exercise. (fda.gov)
  • Heart attack and death have occurred in patients who received Lexiscan (regadenoson) or Adenoscan (adenosine) for a cardiac nuclear stress test. (fda.gov)
  • Tell your health care professional about any heart problems before you have a cardiac nuclear stress test. (fda.gov)
  • Talk to your health care professional if you have any questions or concerns about having a cardiac nuclear stress test, or about any cardiac nuclear stress test agent, including Lexiscan or Adenoscan. (fda.gov)
  • A clinician may ask you to take a stress test to determine if you have cardiac disease and assess your heart attack risk. (healthline.com)
  • The following are some frequently asked questions about cardiac stress testing. (healthline.com)
  • however, this produces increased afterload that causes further cardiac stress and damages myocardium. (medscape.com)
  • CAD), a blood supply that is adequate at rest may be inadequate when cardiac demands are increased by exercise or other forms of stress. (msdmanuals.com)
  • Evidence exists that subendocardial perfusion occurs during the diastolic period. (onteenstoday.com)
  • An index of subendocardial perfusion was also significantly depressed for up to 110 minutes after firefighters. (cdc.gov)
  • Perfusion abnormalities were fixed in 416 (30%) patients and reversible in 445 (32%) patients. (eur.nl)
  • Conclusion: Myocardial perfusion abnormalities on stress 99mTc-tetrofosmin tomography are independently associated with long-term risk of death. (eur.nl)
  • The extent of perfusion abnormalities is a major determinant of mortality. (eur.nl)
  • Perfusion abnormalities, reverse redistribution, heart/lung ratio, changes in LV cavity size and global function were assessed. (uanl.mx)
  • Sixty % of the patients had evidence of CAD in form of either fixed or reversible perfusion abnormalities. (uanl.mx)
  • Mean extent of the perfusion abnormalities were 3.7 segments (out of 20) ± 2. (uanl.mx)
  • In hypertension, capillary rarefaction induces an increase in blood pressure, a relative decrease in tissue perfusion and an increased cardiovascular risk. (onteenstoday.com)
  • Pharmacologic stress testing, established after exercise testing, is a diagnostic procedure in which cardiovascular stress is induced by pharmacologic agents in patients with decreased functional capacity or in patients who cannot exercise. (medscape.com)
  • Screen all candidates for nuclear stress tests to determine their cardiovascular fitness for the 2 drugs. (medscape.com)
  • 18 Quantitative CMR myocardial perfusion mapping to assess hyperaemic response to adenosine stress: a new reference standard? (bmj.com)
  • In nuclear Cardiology, the safety of adenosine stress has been confirmed in large-scale studies, although the data is more limited in the CMR setting. (biomedcentral.com)
  • In this study, we sought to determine the safety and tolerability of adenosine stress CMR in patients with CAD. (biomedcentral.com)
  • What is medium size severe reversible perfusion defect mid inferior wall to apex? (medhelp.org)
  • The degree of reversibility of a perfusion defect is identified on post-stress images as an area of decreased radiopharmaceutical activity that improves or disappears on rest or redistribution images. (onteenstoday.com)
  • METHODS: Thirty-four patients who had a nuclear stress test and invasive angiography were included in the study. (wustl.edu)
  • Summary: We report the feasibility of first pass vasodilator-stress myocardial perfusion CMR in mice on a whole-body 3Tesla scanner and demonstrate a 2.6 fold increase of stress over rest myocardial blood flow in good agreement with microspheres. (biomedcentral.com)
  • Vasodilator stress was induced using a slow injection of dipyrimadole via a tail vein catheter. (biomedcentral.com)
  • Hyperaemic myocardial stress perfusion CMR in mice has however not been reported. (biomedcentral.com)
  • I had a Nuclear Stress Test in April 2022. (medhelp.org)
  • Why would a doctor order a nuclear stress test? (onteenstoday.com)
  • Why it's done You may need a nuclear stress test if you have signs or symptoms of heart disease such as chest pain or shortness of breath. (onteenstoday.com)
  • A nuclear stress test may also be used to guide your treatment if you've been diagnosed with a heart condition. (onteenstoday.com)
  • The nuclear stress test takes about four hours to complete. (ottawaheart.ca)
  • If you have any questions prior to your nuclear stress test, please call 613-696-7066, Monday to Friday, 7:30 a.m. to 4 p.m. (ottawaheart.ca)
  • Nuclear medicine has been leading perfusion scanning for some time, although the modality has certain pitfalls. (wikipedia.org)
  • Consider 2 other nuclear stress test agents - intravenous dipyridamole , which is FDA-approved for this use, and dobutamine , which is not FDA-approved. (medscape.com)
  • Screen all nuclear stress test candidates for their suitability to receive Lexiscan or Adenoscan. (fda.gov)
  • Conclusions: Patients with suspected MVA have lower global MP at stress than healthy volunteers but higher than patients with CAD. (lu.se)
  • Conclusions: Stress CMR was effective in risk-stratifying patients with reduced LV ejection fractions. (uky.edu)
  • Two sets of images are taken, one after an injection at rest and another after an injection during a stress test - either exercise stress on a treadmill or drug-induced stress with persantine (dipyridamole) medication, which simulates exercise. (ottawaheart.ca)
  • The most widely available pharmacologic agents for stress testing are dipyridamole (Persantine), adenosine , regadenoson (Lexiscan), and dobutamine . (medscape.com)
  • However, related studies are absent on which link in the acupuncture will motivate the regulation of the synthesis and release of NO. In this study, we try to observe the influence of electroacupuncture (EA) on the NO concentration and BP in the liver tissue of the mice through inhibiting the activity of eNOS and discuss the relationships between NO levels and hepatic blood perfusion (HBP) regulation by EA. (hindawi.com)
  • Perfusion is the passage of fluid through the lymphatic system or blood vessels to an organ or a tissue. (wikipedia.org)
  • The goal of management is early recognition in order to restore tissue perfusion and thereby prevent progression to multisystem organ failure and death. (medscape.com)
  • The microscale model based on a micro-computed tomography (pCT) reconstruction of a poly(ethylene glycol terephthalate)/poly(butylene terephthalate) (PEGT/PBT) foam scaffold, was developed to assess the influence of the scaffold micro-architecture on local shear stress and oxygen levels within the scaffold pores, Experiments were performed to derive specific oxygen consumption rates for constructs perfused under flow rates of 0.3 and 0.03 ml min(-1). (unibas.ch)
  • Ved koronar angioplastik hos mennesker er det vist, at akut myokardieiskæmi (under balloninflation) på mindre end et minut inducerer en række iskæmiske manifestationer, som begynder med diastolisk dysfunktion efterfulgt af påvirket systolefunktion, iskæmiske ekg-forandringer og endelig angina pectoris, den såkaldte iskæmikaskade (1). (ugeskriftet.dk)
  • so I got my husbands stress test results back and I have called his cardiologist several times and have not gotten a call back. (medhelp.org)
  • Can you pass a stress test and still have blockage? (onteenstoday.com)
  • But normal results from a stress test do not rule out the possibility of a future heart attack. (onteenstoday.com)
  • A stress technologist will explain the stress portion of the test to you and answer any questions you may have. (ottawaheart.ca)
  • You will then undergo the stress test. (ottawaheart.ca)
  • When the stress test is completed, you will have 30 to 45 minutes to eat a light meal. (ottawaheart.ca)
  • Preparing for a Stress Test? (healthline.com)
  • They may either recommend a treadmill (exercise) stress test or a pharmacologic (chemical) stress test, when they give you medications to increase your heart rate. (healthline.com)
  • The following guidelines may help you understand what to expect if you are about to take a stress test . (healthline.com)
  • You may wish to bring a light snack with you so you can eat something after you complete your stress test. (healthline.com)
  • Can I drink water before a stress test? (healthline.com)
  • You can usually drink water and other clear liquids before your stress test. (healthline.com)
  • It's important to avoid caffeine before a stress test. (healthline.com)
  • If taking a chemical stress test , avoid caffeine for at least 12 to, ideally, 24 hours before your test. (healthline.com)
  • Caffeine blocks the effectiveness of adenosine, a medication that doctors commonly give during a chemical stress test. (healthline.com)
  • Avoid caffeinated drinks to help ensure your stress test is as accurate as possible. (healthline.com)
  • Avoid smoking or using any tobacco products before a stress test. (healthline.com)
  • Unless otherwise directed, you can take a shower before your stress test. (healthline.com)
  • Can I drive myself to and from a stress test? (healthline.com)
  • While some healthcare professionals may allow you to drive yourself to and from a stress test, others may ask that you have someone to drive you home after. (healthline.com)
  • Because you receive medications or perform exercise in a way that stresses your heart, it's hard to predict how you will feel after the test. (healthline.com)
  • What can cause you to fail a stress test? (healthline.com)
  • A stress test aims to raise your heart rate to an expected value for your age . (healthline.com)
  • Chronotropic incompetence has independent and incremental prognostic value in predicting all-cause mortality in patients with suspected CAD undergoing exercise stress-MPS. (unina.it)
  • 17-87 y) who consecutively underwent CT-attenuation-corrected myocardial perfusion studies during 2 periods of approximately 1 mo each (6/10/04 to 7/13/04 and 4/1/05 to 4/26/05). (snmjournals.org)
  • Invasive testing is often used as the first-line investigation, and there is limited evidence as to whether stress testing can effectively provide risk stratification. (uky.edu)
  • Risk stratification using gated stress m. (comu.edu.tr)
  • First pass contrast-enhanced myocardial perfusion is the standard CMR method for the estimation of MBF and MBF reserve in man, but is challenging in rodents because of the constraints related to the high temporal and spatial resolution requirements. (biomedcentral.com)
  • Makowski M, Jansen C, Webb I, Chiribiri A, Nagel E, Botnar R, Kozerke S, Plein S: First-pass contrast-enhanced myocardial perfusion MRI in mice on a 3-T clinical MR scanner. (biomedcentral.com)
  • Perfusion measurements are taken by comparing the radioactivity of selected regions within the body to radioactivity of blood samples withdrawn at the time of microsphere injection. (wikipedia.org)
  • Interestingly, targeted mutation of the GluA1 phosphorylation site Ser831 significantly inhibited stress-induced prolongation of incisional pain. (jneurosci.org)
  • Results: Global perfusion was lower during stress in patients with suspected MVA (2.9 ± 1.0 ml/min/g) compared with healthy volunteers (3.7 ± 1.1 ml/min/g, p = 0.018), but higher compared with CAD patients (2.0 ± 0.9 ml/min/g, p = 0.019). (lu.se)
  • Furthermore, there seems to be a sex difference in global MP at stress both in healthy volunteers and in patients with suspected MVA, with higher global MP in females, which implies a need for sex-specific normal limits when assessing quantitative MP. (lu.se)
  • We studied 866 patients with suspected CAD undergoing exercise stress-MPS as part of their diagnostic program. (unina.it)