• Cefamandole (also known as cephamandole) is a broad-spectrum cephalosporin antibiotic. (ncats.io)
  • Thus, these drugs are active against Escherichia coli and Klebsiella and Proteus species (though several strains of these organisms have developed resistance). (britannica.com)
  • Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. (ajlmonline.org)
  • cefuroxime and cefamandole) and third-generation ones (such as ceftazidime) tend to be more effective against gram-negative bacterial species that are resistant to the first-generation cephalosporins. (britannica.com)
  • Escherichia coli transferable plasmids, and the gene was transferred to E. strains producing CTX-M-2 -lactamase, one of the CTX- coli CSH2 with a very high frequency (2 x 10-4 to 6 x 10-1 per donor cells) by conjugation. (cdc.gov)
  • When the strain produces class A -lacta- cephamycinases, which confer resistance to expanded- mases, including TEM- or SHV-derived ESBLs, or CTX- spectrum cephalosporins (22,23), and no CTX-M-type - M-type enzymes, the color of a disk containing ben- lactamase producer has been isolated from animals. (cdc.gov)
  • Several questions regarding the of strains producing broad-spectrum class A -lactamases origin and mode of proliferation of the CTX-M-type -lac- in Japan. (cdc.gov)
  • However, with the introduction and widespread use of both oxacillin and methicillin, antibiotic-resistant strains called methicillin-resistant and oxacillin-resistant Staphylococcus aureus (MRSA/ORSA) have become increasingly prevalent worldwide. (mdwiki.org)
  • ESBL producers would be rarely isolated and that metallo- strains producing extended-spectrum -lactamases -lactamases would be isolated often in Japan. (cdc.gov)
  • RESEARCH about strains in animals producing ESBLs or CMY-type respectively. (cdc.gov)
  • Cefamandole under brand name mandol is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms such as: lower respiratory infections, including pneumonia, caused by S. pneumoniae. (ncats.io)
  • Double-blind trials have reported faster recovery from athletic injuries, including sprains and strains, and earlier return to activity using eight tablets daily of trypsin/chymotrypsin, four to eight tablets daily of papain, eight tablets of bromelain (single-blind only), or a combination of these enzymes. (mottchildren.org)
  • When the strain produces class A -lacta- cephamycinases, which confer resistance to expanded- mases, including TEM- or SHV-derived ESBLs, or CTX- spectrum cephalosporins (22,23), and no CTX-M-type - M-type enzymes, the color of a disk containing ben- lactamase producer has been isolated from animals. (cdc.gov)
  • On the basis of the MIC50 and MIC90 values of ampicillin and five cephalosporins for penicillin-resistant strains, it was established that ampicillin and cephalexin were not superior to penicillin. (nih.gov)
  • The therapeutic alternative to penicillin in the treatment of respiratory tract infection may be second-generation cephalosporins such as cefuroxime or cefamandole. (nih.gov)
  • In vitro susceptibility of Streptococcus pneumoniae strains to nine beta-lactam antibiotics and the killing kinetics of cephalosporins alone and in combination with vancomycin or gentamicin. (nih.gov)
  • The in vitro activity of cefuroxime, a cephalosporin antibiotic, was investigated against 604 isolates and compared with the activity of other beta-lactam compounds. (nih.gov)
  • it inhibited isolates of E. coli and Klebsiella resistant to cefamandole and inhibited Enterobacter and Citrobacter resistant to cefoxitin. (nih.gov)
  • Many isolates of Serratia, some indole-positive strains of Proteus, and Bacteroides fragilis were resistant to cefuroxime. (nih.gov)
  • An epidemiological survey of penicillin resistance as determined by minimum inhibitory concentrations (MICs) in Streptococcus pneumoniae strains collected from several Hungarian laboratories in 1988-1989 indicated a prevalence of 58% among a total of 135 isolates. (nih.gov)
  • The results for the strains tested with the original nine drugs in 1983 were compared with those for 1,292 isolates tested in 1981 and 1982. (duke.edu)
  • Penicillin-resistant strains were more frequently resistant to non-beta-lactam antibiotics (tetracycline, erythromycin, co-trimoxazole, and chloramphenicol) than were penicillin-sensitive strains. (nih.gov)
  • Several questions regarding the of strains producing broad-spectrum class A -lactamases origin and mode of proliferation of the CTX-M-type -lac- in Japan. (cdc.gov)
  • Escherichia coli transferable plasmids, and the gene was transferred to E. strains producing CTX-M-2 -lactamase, one of the CTX- coli CSH2 with a very high frequency (2 x 10-4 to 6 x 10-1 per donor cells) by conjugation. (cdc.gov)
  • [14] Thus distortion causing the substrate molecule to adopt a strained conformation similar to that of the transition state will lower the energy barrier of the reaction. (cloudfront.net)