• In this regard, photoresponsive DDSs that employ light as an external stimulus can offer a precise spatiotemporal control of drug release at desired sites of interest. (biomedcentral.com)
  • Ethoxyquin (EQ), a quinolone-based antioxidant, has demonstrated neuroprotective properties against several neurotoxic drugs in a phenotypic screening and is shown to protect axons in animal models of chemotherapy-induced peripheral neuropathy. (nature.com)
  • Although general therapeutic strategies and existent nanomedicine have been applied in relating cancer treatments, the side effects and potential damage induced by the off-target effect greatly lower the therapeutic efficiency. (frontiersin.org)
  • With the support of various diagnosis technologies including positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT), surgery, radiotherapy, chemotherapy, and hormone therapy are generally applied to treat patients with cancer, including those three deadliest carcinomas. (frontiersin.org)
  • In this review, the development of NIR photoresponsive DDSs in last several years for cancer photo-chemotherapy are summarized. (biomedcentral.com)
  • Herein, we summarize the recent development of NIR photoresponsive DDSs with on-demand drug release profiles for cancer photo-chemotherapy. (biomedcentral.com)
  • It was hypothesized that dopamine release in the striatal system induced by pleasure songs are involved in the cardiac autonomic regulation. (bvsalud.org)
  • The prevention of diabetes-induced mtDNA deletions may be a potential mechanism of the neuroprotective effects of EQ in diabetic neuropathy. (nature.com)
  • We previously identified ethoxyquin (EQ) as a potent neuroprotective compound through a phenotypic screen against three neurotoxic drugs and demonstrated that it prevents development of peripheral neuropathy in paclitaxel and cisplatin models of chemotherapy-induced peripheral neuropathy (CIPN). (nature.com)
  • Despite the complexity of genetic alterations in cancer, some cures have been achieved in certain malignancies with combination chemotherapy, such as childhood leukemia, Hodgkin lymphoma, testicular cancer, and diffuse large B-cell non-Hodgkin lymphoma. (medscape.com)
  • Cisplatin, a platinum compound, is an anticancer drug widely used for the chemotherapy of different malignancies. (springer.com)
  • Present evidence suggests that the endocannabinoids and their receptors constitute a widespread modulatory system that fine tunes bodily responses to a number of stimuli. (erowid.org)
  • Nociceptors- To sense pain, thousands of specialized sensory nerve cells or neurons (nociceptors) throughout the body trigger a series of responses to a noxious (painful) stimulus. (nih.gov)
  • It was hypothesized that dopamine release in the striatal system induced by pleasure songs are involved in the cardiac autonomic regulation. (bvsalud.org)
  • This habit in this young population is increasing the risk for the acquisition of music-induced hearing loss, the author of this study noted that 14% of youth surveyed reported risk behavior for acquiring auditory loss 4 . (bvsalud.org)
  • Clinical outcomes and safety with trabectedin cure in patients with advanced soft tissue sarcomas following fizzle of prior chemotherapy: results of a worldwide expanded access pro- gram study. (daubnet.com)