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  • peptides
  • Check out links to articles that cite our custom service antibodies, peptides, and proteins in major peer-reviewed journals, organized by research category. (abgent.com)
  • Some polypeptide hormones, antimicrobial peptides, and neurotoxins accumulate at the membrane surface prior to locating and interacting with their cell surface receptor targets, which may themselves be peripheral membrane proteins. (wikipedia.org)
  • domains
  • Overexpression of human SCP-2 in murine fibroblasts significantly alters the sterol dynamics of caveolae/lipid rafts, but not nonlipid raft domains, to facilitate retention of cholesterol within the cell. (anticorps-enligne.fr)
  • Ligand binding by the START domain in multidomain proteins can also regulate the activities of the other domains, such as the RhoGAP domain, the homeodomain and the thioesterase domain. (wikipedia.org)
  • Other proteins also exist in the human with domains that are members of the START-based superfamily such as PITP, but are not part of the START domain itself. (wikipedia.org)
  • Membrane binding may also promote rearrangement, dissociation, or conformational changes within many protein structural domains, resulting in an activation of their biological activity. (wikipedia.org)
  • cellular
  • Identifying and characterizing these regulatory elements, as well as how endomembrane trafficking integrates into general cellular physiology, remain a major objective of the membrane trafficking field. (rupress.org)
  • Ubiquinone is a key electron carrier in the electron transport chain of cellular respiration. (wikipedia.org)
  • We use these approaches to identify new functional components of membrane transport and regulatory complexes.The lab also places an emphasis on improving auxin determination and transport assay techniques as well as integration of those techniques with cellular imaging technologies. (purdue.edu)
  • encodes a protein
  • gene in human beings.48 Increased expression of the gene is connected with various types of cancer.49 This gene is an associate from the methionyl aminopeptidase family and encodes a protein that binds to cobalt or manganese ions.48 Literature recommended that MetAP2 takes on a crucial role within the growth of various kinds of tumors via advertising angiogenesis. (recyclers-info.com)
  • This gene encodes a protein that lacks the normal DNA-binding domain contained in other nuclear receptors. (wikipedia.org)
  • vesicles
  • The protein moves within cells on vesicles to the inside face of the cell membrane and once there, it triggers an inward recycling of membrane, which we call 'compensatory endocytosis' - membrane in, membrane out. (sfu.ca)
  • orthologs
  • Currently, our efforts are focused on the structural features of plant ABCB transporters that confer the relative substrate specificity seen in these proteins when compared to mammalian orthologs. (purdue.edu)
  • signalling pathway
  • SIRT1 (zeige SIRT1 ELISA Kits ) gene knock-out may aggravate cartilage degeneration in osteoarthritis by activating the SREBP2 protein-mediated PI3K / AKT (zeige AKT1 ELISA Kits ) signalling pathway, suggesting that SIRT1 (zeige SIRT1 ELISA Kits ) gene may play a protective role against osteoarthritis. (antikoerper-online.de)
  • fatty
  • Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis . (wikipedia.org)
  • The growing fatty acid chain is carried between these active sites while attached covalently to the phosphopantetheine prosthetic group of an acyl carrier protein (ACP), and is released by the action of a thioesterase (TE) upon reaching a carbon chain length of 16 (palmitic acid). (wikipedia.org)
  • metabolism
  • Further highlighting the connections between endomembrane trafficking and lipid metabolism is the recent observation that vesicle trafficking proteins may mediate interorganelle tethering. (rupress.org)
  • biochemistry
  • With state-of-the art molecular biology and protein biochemistry labs, we work with our clients to rapidly evaluate in parallel to identify the optimal expression system for candidate proteins. (abgent.com)
  • zeige
  • This study shows that nonvesicular sterol transport mechanisms and STARD4 in particular account for a large fraction of sterol transport between the plasma membrane and the ERC (zeige ERC1 Antikörper ). (antikoerper-online.de)
  • fluorescent
  • These cells have been genetically modified in the Beh lab to produce an 'artificial staple' protein, as visualized by the green fluorescent spots, assembled from several proteins found in other organisms. (sfu.ca)
  • molecular
  • For example, using molecular genetics my lab has made complex combinations of gene deletions to examine the collective function of large gene families, including those encoding potential protein carriers for moving cholesterol around within cells. (sfu.ca)
  • We discovered that this process is regulated by a protein that acts like a molecular switch. (sfu.ca)
  • gene expression
  • In mature adipocytes, GB reduced the gene expression of resistin, a pro-inflammatory endocrine factor, increased the adiponectin protein levels in a time-dependent manner, and substantially attenuated the TNF-alpha-induced reduction in adiponectin. (mdpi.com)