Alzheimer'sDementiaImpairmentImpairmentsPrevent cognitive declineMaintaining cognitive functionBehavioralGlobal cognitiveConcept of cognitive reserveDeficitsNeuroscienceAbilitiesMultiple cognitive domainsDysfunctionModifies the associationLevel of cognitiveDecline in older adultsCognitionEmotionalFlexibilityStimulationNegativelyOutcomesInterventionsTheoryBrainInterfere with dailyAgingPredictorAbstractClinicalPathologyAlzheimerSystematicFunctionFunctioningBilingualismFunctionalPerformanceEnhancementFindings2001LongitudinalPlateletPreventionYaakovOlderIndividuals
Alzheimer's20
- Aging is a major risk factor for most common neurodegenerative diseases, including mild cognitive impairment, dementias including Alzheimer's disease, cerebrovascular disease, Parkinson's disease, and Lou Gehrig's disease. (wikipedia.org)
- Family, friends and other unpaid caregivers often bear the responsibility of providing daily assistance and emotional support to older adults with severe cognitive impairments such as Alzheimer's , the most common form of dementia. (americashealthrankings.org)
- Cognitive impairment can be caused by conditions such as Alzheimer's disease, brain injury and stroke, as well as treatable health issues like medication side effects, vitamin B12 deficiency and depression. (americashealthrankings.org)
- While people of all ages can experience cognitive impairment, age is the greatest risk factor for Alzheimer's. (americashealthrankings.org)
- The cost of caring for adults with severe cognitive impairment, including Alzheimer's and other dementias, was estimated at $321 billion in 2022 and is projected to reach nearly $1 trillion by 2050. (americashealthrankings.org)
- Over the next five years, some of these healthy individuals developed Mild Cognitive Impairment or Alzheimer's Disease. (bu.edu)
- If keeping your brain active is a good way to prevent cognitive decline, then why did people such as Ronald Reagan and Norman Rockwell develop Alzheimer's disease? (bu.edu)
- The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study. (jamanetwork.com)
- Her overall goal is to investigate the evolution of language use and cognitive decline throughout the course of dementia to help accurate and timely diagnosis, with a focus on Alzheimer's disease and primary progressive aphasia. (ucsf.edu)
- Alzheimer's disease is the most common cause of dementia, a general term for memory loss and other cognitive abilities that interfere with daily life [1] . (globalwellnessguru.com)
- More years of formal education , such as higher levels of schooling, may help build cognitive reserve and resilience against Alzheimer's. (globalwellnessguru.com)
- 10] Scarmeas N, Levy G, Tang MX, Manly J, Stern Y. (2001) Influence of leisure activity on the incidence of Alzheimer's disease. (iaeme.com)
- 15] Stern, Y. (2012) Cognitive reserve in ageing and Alzheimer's disease. (iaeme.com)
- Though it is predominantly self-reported, it is not an event that should be overlooked, considering its significant association with cognitive disorders like Alzheimer's disease, mild cognitive impairment, and so on. (mdpi.com)
- Objective To summarise evidence on the preventive effects of continuing education on mild cognitive impairment and Alzheimer's-type dementia in adults 45 years or older. (bmj.com)
- So how can you build a better brain, empower cognitive reserve, and even prevent Alzheimer's disease? (totalhealthmagazine.com)
- The current study explored whether education, a proxy of cognitive reserve, modifies the association between episodic memory (EM) performance and βeta-amyloid load (Aβ), a biomarker of Alzheimer's disease, in a cohort of cognitively normal older adults. (123dok.net)
- We identified articles for review primarily by conducting a Medline search using the subject headings dementia, mild cognitive impairment, Alzheimer's disease, vascular dementia, frontotemporal dementia, and Lewy body dementia . (cdc.gov)
- Articles included in this review were primarily identified through a Medline search of the terms dementia, mild cognitive impairment, Alzheimer's disease, vascular dementia, frontotemporal dementia, Lewy body dementia, mental disorders, and stigma . (cdc.gov)
- BACKGROUND: Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are common in Veterans and linked to behavioral disturbances, increased risk of cognitive decline, and Alzheimer's disease. (bvsalud.org)
Dementia24
- Declining cognitive functioning and dementia are major Public Health challenges [ 1 ]. (springer.com)
- [ 1 ] Under the current Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) , dementia is considered a major neurocognitive disorder, in which a deficit in cognitive functioning is acquired rather than developmental. (medscape.com)
- As hearing loss is proposed to be one modifiable risk factor for dementia, the impact of auditory rehabilitation on cognitive decline has been gaining increasing attention. (frontiersin.org)
- Hearing loss is also associated with an increased risk of dementia, but using hearing aids can help protect against severe cognitive impairment. (americashealthrankings.org)
- Audiologists and speech-language pathologists (SLP) are important members of interprofessional teams that treat individuals with dementia and can provide vital information about cognitive-communication, language, and feeding/eating/swallowing skills that can contribute to appropriate diagnosis. (asha.org)
- Cognitive changes caused by dementia may impact communication and may cause challenging behaviors (e.g., paranoia, hallucinations, and repetitiousness) and other responsive behaviors (atypical behaviors in response to stimuli that are perceived as stressors in the environment), such as wandering, restlessness, or calling out. (asha.org)
- The implication of the findings is that early life performance on cognitive tests could be used to identify potential at-risk populations who might especially benefit from interventions aimed at modifying their dementia risk, such as those promoting social/mental stimulation," wrote Serhiy Dekhtyar, Karolinska Institutet, Stockholm, to Alzforum. (alzforum.org)
- Her research focuses on the timing and mechanisms of cognitive decline in relation to aging and dementia using linguistic, neuroimaging, and epidemiological methods. (ucsf.edu)
- Previous work has focused on detecting subtle semantic memory impairment in preclinical dementia, developing novel cognitive markers related to biomarkers and future clinical outcomes, and investigating the effects of biological and sociodemographic variables on cognitive and language decline. (ucsf.edu)
- Semantic item-level metrics relate to future memory decline beyond existing cognitive tests in older adults without dementia. (ucsf.edu)
- Association of Subjective Cognitive Decline With Progression to Dementia in a Cognitively Unimpaired Multiracial Community Sample. (ucsf.edu)
- No single risk or protective factor has been identified that fully explains the observed trends, but major societal changes and improvements in living conditions, education and healthcare might have favourably influenced physical, mental and cognitive health throughout the lifecourse, and could be responsible for a reduced risk of dementia in later life. (ukdiss.com)
- This paper investigates the role of brain-based learning tools, like the Muslim spiritual songs 'Nasheed' in maintaining the cognitive reserve (CR) of dementia patients and its role in mitigating the speed of progression of the spillovers of the disease impairment symptoms. (iaeme.com)
- The implication here is to focus on the role of the 'nasheed' like tools, as brain-based learning tools, in maintaining the cognitive reserve of dementia patients and those suffering memory loss due to aging. (iaeme.com)
- 17] Valenzuela MJ, Sachdev P. (2005) Brain reserve and dementia: a systematic review. (iaeme.com)
- Vascular brain injury (VBI) is widely recognized as a common cause of cognitive impairment (vascular cognitive impairment) culminating in vascular dementia. (medscape.com)
- At the most extreme end of the age spectrum, 30% of individuals over 85 years have dementia and another 30% have impaired cognitive function. (medicaleconomics.com)
- Systematic reviews consistently reported a positive association between participation in cognitively stimulating leisure activities and reduced incidence of dementia and improved cognitive test performance. (bmj.com)
- Conclusion Available results demonstrate that cognitive reserve increases through continuing education and show a positive association of cognitive leisure activities with both improved cognitive function and lower dementia incidence. (bmj.com)
- A clinical diagnosis of mild cognitive impairment (MCI) due to AD or mild AD dementia, both with confirmed presence of amyloid beta pathology consistent with AD. (cms.gov)
- Dementia refers not to a single disorder but to a number of syndromes characterized by diverse behavioral, cognitive, and emotional impairments. (cdc.gov)
- Dementia represents a diverse category of syndromes characterized by deficits in memory, cognitive function, and behavior. (cdc.gov)
- To promote cognitive functioning and independence among older adults, public health interventions need to facilitate both early detection and treatment of dementia. (cdc.gov)
- Recent advances in the treatment of dementia may slow the course of cognitive decline, thereby enhancing the quality of life of older individuals as well as decreasing costs associated with institutional care. (cdc.gov)
Impairment7
- Older adults with cognitive impairment spend twice as many days hospitalized as older adults without it. (americashealthrankings.org)
- Mild cognitive impairment (MCI) , also known as mild neurocognitive disorder (mild NCD), is a clinical syndrome that is characterized by a modest decline in one or more cognitive domains. (asha.org)
- The HELIAD is a population-based, multidisciplinary, collaborative study designed to estimate the prevalence and incidence of AD, other dementias, mild cognitive impairment, and other neuropsychiatric conditions of aging in the Greek population and to investigate associations between nutrition and cognitive dysfunction/age-related neuropsychiatric diseases in this Mediterranean population. (karger.com)
- Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. (jamanetwork.com)
- This makes it imperative to find ways to manage the event to enhance the cognitive performance of older adults and/or suppress the rate at which cognitive decline results in impairment. (mdpi.com)
- On these grounds, we evaluated the effects of CS on platelet tPLA 2 activity in a cohort of subjects with mild cognitive impairment (MCI). (pharmaceuticalintelligence.com)
- The finding that the increase of tPLA 2 activity and the severity of the global cognitive status impairment are significantly linked suggests a possible role of tPLA 2 in MCI progression. (pharmaceuticalintelligence.com)
Impairments4
- Delirium-an acute state of confusion associated with temporary, but reversible, cognitive impairments (Mahendra & Hopper, 2013). (asha.org)
- Ischemic strokes and cognitive impairments are the most frequent manifestations, but seizures affect up to 10% of the patients. (uni-bielefeld.de)
- Although no definite conclusions can be drawn from a single case study, our findings point to the presence of additional cognitive changes in CADASIL in middle adulthood, in particular to impairments in the episodic-autobiographical memory domain and social information processing (e.g., social cognition). (uni-bielefeld.de)
- Whether these identified impairments are related to the patient's specific phenotype or to an ascertainment bias (e.g., a paucity of studies investigating these cognitive functions) requires elucidation by larger scale research. (uni-bielefeld.de)
Prevent cognitive decline2
- Can cochlear implantation prevent cognitive decline in the long-term follow-up? (frontiersin.org)
- Large multicenter studies using standardized protocols have to be undertaken in the future to find out whether hearing restoration might help to prevent cognitive decline. (frontiersin.org)
Maintaining cognitive function1
- In addition to preserving a good physical constitution, maintaining cognitive function is quite important ( 2 ). (frontiersin.org)
Behavioral6
- Recent behavioral data have shown that lifelong bilingualism can maintain youthful cognitive control abilities in aging. (jneurosci.org)
- OBJECTIVE: We studied the synergistic effects of PTSD and TBI on behavioral, cognitive, and neuroimaging measures in Vietnam war Veterans. (bvsalud.org)
- ANCOVAs were used to compare Veterans' baseline behavioral and cognitive functioning (Nâ =â 285), white matter microstructure, amyloid-ß (Nâ =â 230), and tau PET (Nâ =â 120). (bvsalud.org)
- RESULTS: Veterans with PTSD and PTSD+TBI, but not Veterans with TBI only, exhibited poorer behavioral and cognitive functioning at baseline than controls. (bvsalud.org)
- The groups did not differ in baseline white matter, amyloid-ß, or tau, nor in behavioral and cognitive functioning, and tau accumulation change. (bvsalud.org)
- CONCLUSIONS: PTSD and PTSD+TBI negatively affect behavioral and cognitive functioning, while TBI does not contribute independently. (bvsalud.org)
Global cognitive4
- Predicted association between Alzheimer disease (AD) pathologic changes and global cognitive function. (jamanetwork.com)
- Predicted association between neurofibrillary tangles and global cognitive function. (jamanetwork.com)
- Results showed that scores before and during the pandemic were the same in memory and attention, whereas global cognitive, executive, and language functions improved. (nature.com)
- Higher apathy was predicted by poorer global cognitive performance, increased anxiety, and emotional dysregulation as measured by a higher ratio of low-to-high frequency heart rate variability. (nature.com)
Concept of cognitive reserve2
- The concept of cognitive reserve (CR) attempts to explain interindividual variability in susceptibility to changes in brain function in pathological, but also normal aging of the brain [ 1 , 2 ]. (scienceopen.com)
- The concept of cognitive reserve (CR) has thereby been proposed to account for the discrepancy between the level of brain pathologies, such as Aβ load, and expected clinical manifestations generally associated with it (10). (123dok.net)
Deficits4
- Cognitive deficits interfere with independence in everyday activities. (asha.org)
- Cognitive deficits do not occur exclusively in the context of delirium. (asha.org)
- Cognitive deficits are not better explained by other mental disorders, such as major depressive disorder or schizophrenia (APA, 2013). (asha.org)
- Cognitive deficits do not interfere with the ability to independently perform everyday activities (although some may require greater effort or use of compensatory strategies). (asha.org)
Neuroscience2
- Handbook of developmental cognitive neuroscience (pp. 281-307). (jbe-platform.com)
- "Cognitive Reserve: From Theory to Intervention," Yaakov Stern, division leader of Cognitive Neuroscience Division, Sergievsky Center, and professor of clinical neuropsychology, Columbia University College of Physicians and Surgeons, 4 p.m. Oct. 24, A115 Crabtree Hall, Pitt Graduate School of Public Health's annual Jay L. Foster Memorial Scientific Lecture, www.upmc.com . (pitt.edu)
Abilities2
- Cognitive functioning includes cognitive abilities, such as episodic memory (EM) and executive functions (EFs). (springer.com)
- Health trajectories may represent a decline, as can be expected with ageing, involving the progressive loss of functional and cognitive abilities, or they may indicate an improvement, in the case of recovery from illness and associated disability [ 7 ]. (biomedcentral.com)
Multiple cognitive domains2
- However, no study had examined how performance in multiple cognitive domains related to disease. (alzforum.org)
- The patient demonstrated on one hand severe and accelerated deteriorations in multiple cognitive domains such as concentration, long-term memory (including the episodic-autobiographical memory domain), problem solving, cognitive flexibility and planning, affect recognition, discrimination and matching, and social cognition (theory of mind). (uni-bielefeld.de)
Dysfunction1
- 16] Sumowski JF, Chiaravalloti N, Deluca J. (2009) Cognitive reserve protects against cognitive dysfunction in multiple sclerosis. (iaeme.com)
Modifies the association1
- Education modifies the association of amyloid but not tangles with cognitive function. (jamanetwork.com)
Level of cognitive2
- Education modifies the relation of AD pathology to level of cognitive function in older persons. (jamanetwork.com)
- Indeed, this capacity to withstand brain damage is largely studied in cases of patients with AD to account for the fact that at equal level of cognitive performance, higher-educated patients present more aggregation of Aβ than less-higher-educated patients (13). (123dok.net)
Decline in older adults1
- Cognitive function and hearing are known to both decline in older adults. (frontiersin.org)
Cognition2
- There is a significant decline from previous levels of performance in one or more cognitive domains, including complex attention, executive function, learning and memory, language, perceptual motor, or social cognition (preferably documented by standardized testing or clinical assessment). (asha.org)
- Cognition, reserve, and amyloid deposition in normal aging. (jamanetwork.com)
Emotional2
- This provides a profile of the optimality of the cognitive and emotional functioning of an individual's brain. (brainid.fi)
- em- behavioural, cognitive and emotional im- phasized that, although there have been pairments. (who.int)
Flexibility1
- We found a significant but variable gain and identified verbal memory, cognitive flexibility, and problem-solving as significant factors. (scienceopen.com)
Stimulation2
- A healthy diet, regular exercise, social activity, and mental stimulation can also help maintain cognitive function. (globalwellnessguru.com)
- in this context, cognitive stimulation (CS) is particularly promising, not only because in animal models it has effective regulating properties [ 7 ], but also because it is non-invasive, has no side effects, and presents no contraindications. (pharmaceuticalintelligence.com)
Negatively1
- High blood pressure, heart disease, stroke, diabetes, and high cholesterol in midlife can all negatively impact cognitive function later in life. (globalwellnessguru.com)
Outcomes3
- We aimed to (i) use the conceptual framework developed to identify indicators of deteriorating health reserves, (ii) construct an overall health measure from these indicators, (iii) evaluate the association between the overall health measure and subsequent health outcomes and (iv) assess the robustness of our method. (biomedcentral.com)
- As far as the therapeutic potentialities of CS are concerned, the protocol not only exerted positive effects on several cognitive outcomes, but also counteracted the peripheral enzymatic deregulation. (pharmaceuticalintelligence.com)
- Older adults have been reported to have increased susceptibility to the adverse effects of SARS-CoV-2 infection, such as fatal outcomes, cognitive decline, and changes in physical and/or mental health. (nature.com)
Interventions2
Theory2
- Both papers lend support to the theory of cognitive reserve. (alzforum.org)
- Theory and research application of the reserve concept. (iaeme.com)
Brain9
- Changes in the brain often occur before symptoms of cognitive difficulty appear, suggesting that it may be possible to delay the onset of symptoms. (americashealthrankings.org)
- Every time you activate your Prefrontal Cortex for reasoning of any kind, even a silly joke, and point-and-click your Hippocampus for long-term memory, you you trigger a neural network in your brain for Cognitive Reserve. (selfgrowth.com)
- Yaacov Stern, Columbia University Medical Center coined the term Cognitive Reserve for lifelong learners who have amyloid plaques and neurofibrillary tangles in their brain, but function as if they are healthy and youthful. (selfgrowth.com)
- Such an approach would also fit into a model of task-related brain activity depending on the level of task demands, which helps to explain interindividual differences in the context of brain reserve and thus of the neural basis of CR [ 13 ]. (scienceopen.com)
- Based on this framework, one would predict that subjects with higher functional brain reserve would also show higher performance in such a task because they can activate more cognitive resources in this condition. (scienceopen.com)
- Yes-ter-day I had the chance to chat with Yaakov Stern, lead-ing Cog-ni-tive Reserve researcher at Colum-bia Uni-ver-si-ty, and then with a group of 25 life-long learn-ers in Ari-zona who attend-ed a brain fit-ness class (hel-lo, Robert and friends! (sharpbrains.com)
- Based on research com-piled from lead-ing sci-en-tists in fields of Neu-ro-science, Geron-tol-ogy, and Cog-ni-tive Sci-ence, and pre-sent-ed in his book "The Sharp-Brains Guide to Brain Fit-ness", Alvaro Fer-nan-dez will pro-vide ways to main-tain and improve your cog-ni-tive health. (sharpbrains.com)
- Now, most excitedly, we know that you can even grow new brain cells, a process called neurogenesis, build new connections between brain cells, a process called neuroplasticity, and enhance your cognitive reserve or the strength of your brain to resist damage. (totalhealthmagazine.com)
- This will require sig-nif-i-cant pro-fes-sion-al devel-op-ment efforts, giv-en that most doc-tors today were trained under a very dif-fer-ent under-stand-ing of the brain than the one we have today. (sharpbrains.com)
Interfere with daily1
- It is characterized by a progressive decline in memory and other cognitive domains that are severe enough to interfere with daily living and independent functioning. (asha.org)
Aging6
- Here, we provide the first direct evidence of a neural basis for the bilingual cognitive control boost in aging. (jneurosci.org)
- However, the functional neuroanatomic bases of bilingual cognitive control advantages in aging remain unknown. (jneurosci.org)
- Limited research is available on the relationship between social stress and risk of declining cognitive functioning in aging individuals. (springer.com)
- The observed trajectories of two exemplary cognitive subdomains (delayed recall and working memory) were then fitted over time using multilevel growth models to adjust for sociodemographic covariates and compared with 5-year longitudinal data from a sample of older adults from the representative Survey of Health, Aging and Retirement in Europe (SHARE) study. (frontiersin.org)
- 3 ] proposed four factors (general intelligence ("g"), complex mental activity, processing resources, and executive function) as "potential reserve proxies" for CR in normal aging. (scienceopen.com)
- Studies that have early-life cognitive ability measures are rare, and the current study offers interesting prospects for future research that may further the understanding of successful aging. (neurology.org)
Predictor2
- Although amyloid angiopathy has been associated with lobar hemorrhages, it is not a strong predictor of cognitive status. (medscape.com)
- EM decline is recognized as one of the first clinical signs of AD and thus the best cognitive predictor of future conversion to the disease (5, 6). (123dok.net)
Abstract1
- As part of Project Talent, 377,016 students from 1,225 secondary schools in the U.S. underwent detailed tests that probed general cognitive ability, language skills, perception, visualization, and mathematics, as well as complex intellectual aptitudes such as creativity and abstract reasoning. (alzforum.org)
Clinical2
- An overall health measure was constructed via the sum of three selected indicators of deteriorating health reserves in mid-life: chronic widespread pain (CWP), Clinical Interview Schedule - revised (CIS-r), and allostatic load (AL). (biomedcentral.com)
- Aβ begins to accumulate before the first clinical signs of AD and is associated with an increased risk for future cognitive decline (7, 8). (123dok.net)
Pathology2
- Although some older individuals have a significant amount of Aβ pathology, their cognitive performances are still within normal limits (9). (123dok.net)
- Education is one of the most studied proxies of CR and has been widely recognized as a moderator of cognitive changes associated with an underlying pathology, such as AD (11, 12). (123dok.net)
Alzheimer1
- Alzheimer disease and cognitive reserve: variation of education effect with carbon 11-labeled Pittsburgh Compound B uptake. (jamanetwork.com)
Systematic2
- The use of the Digit Symbol Substitution Test (DSST), a multi-tasking cognitive measure [ 15 ], in a testing-the-limits paradigm with systematic repetition offers a way to assess CR in a dynamic way. (scienceopen.com)
- Fjorback LO, Arendt M, Ørnbøl E, Fink P, Walach H. Mindfulness-Based Stress Reduction and Mindfulness-Based Cognitive Therapy - a systematic review of randomized controlled trials. (bsl.nl)
Function2
- Studies that track a person's cognitive function from youth to old age are rare. (alzforum.org)
- For example, self-reported data from an online survey were used to examine the impact of the COVID-19 period on well-being, activity levels, sleep quality, and cognitive function 7 . (nature.com)
Functioning2
- Cognitive reserve (CR) helps explain the mismatch between expected cognitive decline and observed maintenance of cognitive functioning in older age. (scienceopen.com)
- Finally, the lack of longitudinal studies with neuropsychological data collected before the pandemic made it impossible to detect potential changes in cognitive functioning and/or mood, limiting the resulting findings to short-term effects and neglecting the crucial role of "baseline" performance. (nature.com)
Bilingualism1
- These results suggest that lifelong bilingualism offsets age-related declines in the neural efficiency for cognitive control processes. (jneurosci.org)
Functional1
- Evidence in support of this idea from animal work has also suggested that this cognitive deficit is due to functional and biochemical factors such as changes in enzymatic activity, chemical messengers, or gene expression in cortical circuits. (wikipedia.org)
Performance6
- Almost all other cognitive domains trended in the same direction, meaning poor performance tended to increase risk. (alzforum.org)
- In this study, we applied a testing-the-limits paradigm to a group of 136 healthy elderly subjects (60-75 years) and additionally examined the possible contribution of complex mental activities and quality of sleep to cognitive performance gain. (scienceopen.com)
- It is also plausible that other variables, such as mood [ 9 ] and quality of sleep [ 10 ] may also determine cognitive performance in older age. (scienceopen.com)
- To examine associations between complexity of main lifetime occupation and cognitive performance in later life. (neurology.org)
- General linear model analyses indicated that complexity of work with people and data were associated with better cognitive performance at age 70, after including age 11 IQ, years of education, and social deprivation. (neurology.org)
- 12] Steffener J, Reuben A, Rakitin BC, Stern Y. (2011) Supporting performance in the face of age-related neural changes: testing mechanistic roles of cognitive reserve. (iaeme.com)
Enhancement1
- Angelakis E., Stathopoulou S., Frymiare J.L., Green D.L., Lubar J.F., Kounios J. EEG neurofeedback: a brief overview and an example of peak alpha frequency training for cognitive enhancement in the elderly. (brainid.fi)
Findings2
- Additional longitudinal analysis confirmed these findings in a rigorous multilevel approach in two exemplary cognitive subdomains. (frontiersin.org)
- The current findings are supportive of the differential preservation hypotheses that more stimulating environments preserve cognitive ability in later life, although the continued effects into old age are still debated. (neurology.org)
20011
- Cognitive control refers to the ability to flexibly shape thoughts and behavior to meet internal goals in the face of constantly changing environmental demands ( Miller and Cohen, 2001 ). (jneurosci.org)
Longitudinal1
- The conclusion of this 76 page paper is that older adults experience longitudinal analytic cognitive decline. (medicaleconomics.com)
Platelet1
- The present study showed that in subjects with MCI, platelet tPLA 2 activity correlates with patients' cognitive conditions, and that CS acts selectively on the enzyme, i.e., it modulates the parameter only in individuals with deregulated values in comparison to the healthy elderly. (pharmaceuticalintelligence.com)
Prevention2
- As no causal treatment exists to reverse cognitive decline, efforts must focus on prevention ( 4 ). (frontiersin.org)
- Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. (bsl.nl)
Yaakov1
- Yaakov Stern, Columbia University, New York, praised the authors for focusing on data collected during adolescence. (alzforum.org)
Older2
- Subjective cognitive decline (SCD) is one of those significant concerns faced by older individuals. (mdpi.com)
- She is currently directing a multi-year grant that provides cognitive fitness programs for older adults at Laurel Lake Retirement Community in Hudson, Ohio. (nursingworld.org)
Individuals1
- In reality, any consistent or worsening cognitive problems should be evaluated by a doctor, even in younger individuals. (globalwellnessguru.com)