Stent restenosis with stent. Medical search. Frequent questions

Intracoronary in-stent restenosis (ISR) is more common with bare metal stents. (ijcdw.org)
Nearly 96.0% and 94.0% of participants in normal and elevated Lp-PLA2 groups were placed with drug-eluting stents, and the others were with bare-metal stents. (biomedcentral.com)
Drug-eluting stents (DES) improved the principles of bare metal stents (BMS) by local drug release to inhibit neointimal growth. (scirp.org)
2009) 5-Year Clinical Outcomes after Sirolimus-Eluting Stent Implantation Insights from a Patient-Level Pooled Analysis of 4 Randomized Trials Comparing Sirolimus-Eluting Stents with Bare-Metal Stents. (scirp.org)
While DES reduce restenosis, they cost more than bare metal stents (BMS), and necessitate prolonged dual antiplatelet therapy (DAPT) that increases costs, bleeding risk, and risk of complications if DAPT is prematurely discontinued. (ku.edu)
In 1996, Johnson & Johnson was the undisputed king of bare-metal stents. (technologyreview.com)
Patients who received at least one DES (n = 4754) were compared with those who received only bare metal stents (BMS) (n = 4956) at the index procedure. (lu.se)

However, limited data on the long term outcome of myocardial bridge stenting has shown a higher restenosis rate comparing to stenting of de novo atherosclerotic lesions. (minervamedica.it)
Drug-eluting stenting of de novo atherosclerotic lesions has reduced the rate of restenosis comparing to bare metal stenting, but there is no available data on drug-eluting myocardial bridge stenting. (minervamedica.it)
Discussion: Intravascular lithotripsy is a promising tool for the treatment of extremely calcified lesions including calcific neoatherosclerosis of in-stent restenosis. (upf.edu)
In-stent restenosis lesions were divided into 2 groups according to the use of cutting balloon (n = 76) or conventional balloon angioplasty (n = 407) before γ-brachytherapy. (illinois.edu)
Real-world data from the IN.PACT Global Study demonstrating safe and effective treatment of complex in-stent restenosis lesions was first presented on the scientific podium at VIVA 2015 (Las Vegas, USA). (vascularnews.com)
The mean length of lesions was 17.2±10.5cm, with 34% occluded in-stent restenosis lesions. (vascularnews.com)
The Rotarex™ Atherectomy System is designed to efficiently remove both plaque and thrombus by utilizing three distinct mechanisms of action to treat PAD lesions including in-stent restenosis. (bd.com)
The safety and effectiveness of the Zilver PTX stent for the treatment of femoropopliteal ISR lesions demonstrated that this device provides a favorable treatment option in this difficult-to-treat subgroup. (bvsalud.org)
Background Research has shown that the prognosis of in-stent restenosis (ISR) lesions after drug-coated balloon (DCB) angioplasty can differ in relation to in-stent neointimal characteristics. (elsevierpure.com)
The Resolute Integrity Zotarolimus-Eluting Coronary Stent System is indicated for improving coronary luminal diameters in patients, including those with diabetes mellitus, with symptomatic ischemic heart disease due to de novo lesions of length ≤ 27 mm in native coronary arteries with reference vessel diameters of 2.25 mm to 4.20 mm. (medtronic.com)
In addition, the Onyx Frontier™ zotarolimus-eluting coronary stent system is indicated for treating de novo chronic total occlusions and non-left main bifurcation lesions utilizing the provisional bifurcation stenting technique. (medtronic.com)
Uses of balloon catheters or BMS for the treatment of coronary artery lesions shows good short-term results but long-term follow up revealed restenosis in up to 20%-30% of patients. (scirp.org)
The Promus ELITE Everolimus-Eluting Platinum Chromium Coronary Stent System is indicated for improving luminal diameter in patients, including those with diabetes mellitus, with symptomatic heart disease or documented silent ischemia due to de novo lesions in native coronary arteries ≥2.25 mm to ≤4.00 mm in diameter in lesions ≤34 mm in length. (bostonscientific.com)
A total of 87 de novo lesions were treated by IVL with the following indications: 25 before attempting other balloon-based devices (primary IVL), 51 after the failure of non-compliant balloon dilatation (secondary IVL), and 11 after stent implantation because of stent under expansion (bailout IVL). (frontiersin.org)
In 23 lesions, IVL was used for the treatment of in-stent restenosis (ISR). (frontiersin.org)
The number of lesions treated with DES to prevent one restenosis ranged from 11 to 47 in various subgroups. (lu.se)

Prolonged dual antiplatelet therapy and avoidance of a new stent has been shown to reduce late thrombosis in patients treated with vascular brachytherapy. (elsevierpure.com)
The use of this product carries the same risks associated with coronary artery stent implantation procedures, which include subacute and late vessel thrombosis, vascular complications and/or bleeding events. (medtronic.com)
Stent thrombosis is a low-frequency event that is frequently associated with MI or death. (medtronic.com)
The use of a drug-eluting stent (DES) outside of the labeled indications, including use in patients with more tortuous anatomy, may have an increased risk of adverse events, including stent thrombosis, stent embolization, myocardial infarction (MI), or death. (medtronic.com)
The concern of stent thrombosis still an issue and dual antiplatlets therapy (DAPT) is mandatory for variable time ranging from one month to one year. (scirp.org)
Stent thrombosis is a low-frequency event that current drug-eluting stent (DES) clinical trials are not adequately powered to fully characterize. (bostonscientific.com)
Stent thrombosis is frequently associated with myocardial infarction (MI) or death. (bostonscientific.com)
In the clinical trials analyzed to date, differences in the incidence of stent thrombosis have not been associated with an increased risk of cardiac death, MI, or all-cause mortality. (bostonscientific.com)
Additional data from longer-term follow-up of the PLATINUM clinical trials and analyses of stent thrombosis related to DES are expected and should be considered in making treatment decisions as data become available. (bostonscientific.com)
The other is the formation of clots inside the stent, called stent thrombosis. (harvard.edu)
As a result, blood clots could form on the stent (stent thrombosis). (harvard.edu)
Stent thrombosis can happen at any time, but most clots form within the first month of receiving a stent. (harvard.edu)
Skipping or stopping the anti-clotting medications is the biggest risk factor for stent thrombosis. (harvard.edu)
Mortality, major adverse cardiovascular events (MACEs), target vessel failure, and stent thrombosis (ST) occur more frequently as the result of calcium-mediated poor lesion preparation, stent under expansion, and stent malapposition ( 2 ). (frontiersin.org)

Approximate 50% reductions in the rates of target lesion restenosis and target vessel myocardial infarction (MI) accounted for the superior findings with the AGENT DCB over conventional balloon angioplasty. (medscape.com)
There was no stent rethrombosis with the DCB vs 3.9% with the conventional balloon angioplasty. (medscape.com)
In-stent restenosis (ISR) is one of the main complications in patients undergoing percutaneous coronary angioplasty, and microRNAs participate in the contractile-to-synthetic phenotypic switch of vascular smooth muscle cells, a hallmark of restenosis development. (hindawi.com)
Restenosis results from a reduced diameter of the lumen of a blood vessel following percutaneous coronary angioplasty (PCA). (hindawi.com)
The decrease in restenosis rates compared with conventional angioplasty, stable angiographic results with a subsequent decreased need for urgent or emergency coronary bypass graft surgery, and reliable treatment of acute or threatened closure resulting from conventional angioplasty have all made stents the treatment of choice for many patients undergoing percutaneous intervention. (elsevierpure.com)
Neointimal hyperplasia with vascular smooth muscle cells is even more exaggerated with stent placement than with conventional angioplasty. (elsevierpure.com)
Cutting balloon angioplasty, compared with conventional balloon angioplasty, in patients undergoing γ-brachytherapy for in-stent restenosis is associated with less requirement for new stents (11% vs 22%, p = 0.02) but similar target vessel revascularization (35.1% vs 29.8%, p = 0.4) at follow-up. (illinois.edu)
According to a company release, the FDA approval was based on in-stent restenosis data from the IN.PACT Global Study, comparing use of the device to standard percutaneous balloon angioplasty control. (vascularnews.com)
Additional in-stent restenosis data from the IN.PACT Global Study and a percutaneous balloon angioplasty control were used to gain FDA approval of the in-stent restenosis indication. (vascularnews.com)
Restenosis after balloon angioplasty and stenting is exacerbated by low flow. (edu.au)
Flow-dependent restenosis after angioplasty but not stenting is prevented by the antioxidant pyrrolidine dithiocarbamate (PDTC). (edu.au)
0.05) in balloon-injured but not in stented segments, and abrogated the effect of low flow on restenosis after angioplasty, similar to the morphological effects of PDTC. (edu.au)
We have decided to make no changes in coverage of patient groups for percutaneous transluminal angioplasty (PTA) of the carotid artery concurrent with stenting (Medicare NCD Manual 20.7B3 and B). We have decided to retain our existing coverage policy with a slight revision to the language regarding embolic protection devices. (cms.gov)
A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. (hopkinsmedicine.org)
1987) Intravascular Stents to Prevent Occlusion and Restenosis after Transluminal Angioplasty. (scirp.org)
1994) A Comparison of Balloon-Expandable-Stent Implantation with Balloon Angioplasty in Patients with Coronary Artery Disease. (scirp.org)
Stents are the mesh tubes that prevent arterial collapse after balloon angioplasty, the principal treatment for atherosclerosis: A balloon is inserted into an artery to clear away plaque and is removed. (technologyreview.com)
Stents revolutionized the treatment of atherosclerosis in coronary and peripheral arteries, but they did little to address one of the chief problems with balloon angioplasty. (technologyreview.com)
Possibility of doing angioplasty or stenting on a 100% total occlusion? (ptca.org)
What is the cost of an angioplasty with stents? (ptca.org)
What are the chances of occlusion reoccurring after angioplasty with stent? (ptca.org)

Medtronic ($MDT) won FDA approval for its drug-coated balloon (DCB) to treat in-stent restenosis (ISR) in patients with peripheral artery disease (PAD). (fiercebiotech.com)
This is the first drug-coated balloon to gain approval to treat in-stent restenosis in the USA. (vascularnews.com)

The primary endpoint was target lesion failure at 1 year, a composite of target lesion restenosis, target vessel-related MI, or cardiac death. (medscape.com)
Subgroup analyses of the primary outcome in terms of sex, age, diabetes, vessel size, or single or multiple stent layers all trended in favor of AGENT DCB but were not statistically significant for interaction. (medscape.com)
This multiscale model includes single-scale models for stent deployment, blood flow and tissue growth in the stented vessel, including smooth muscle cell (SMC) proliferation and extracellular matrix (ECM) production. (springer.com)
The validation procedure uses data from porcine in vivo experiments, by simulating stent deployment using stent geometry obtained from micro computed tomography (micro-CT) of the stented vessel and directly comparing the simulation results of neointimal growth to histological sections taken at the same locations. (springer.com)
For 14 days post-stenting the relative neointimal area, averaged over all vessel sections considered, was 20 ± 3% in vivo and 22 ± 4% in silico . (springer.com)
During the stenting procedure, the narrowed artery is damaged by the stent struts being pressed into the vessel wall, as well as by the expanding balloon which is used to distend the artery and deploy the stent. (springer.com)
This in turn causes a healing response in the vessel wall, which, if it becomes excessive, can cause a new narrowing of the vessel, or in-stent restenosis (ISR). (springer.com)
ISR is associated with excessive damage to the vessel wall and with disturbed flow patterns in the stented vessel, in particular with low values of wall shear stress (WSS). (springer.com)
The main objective o f this study is to use the finite element method to simulate these stenting procedures, and to examine the stresses induced within the stented arterial vessel walls by the stents, thus enabling the mechanical stimuli for in-stent restenosis to be identified. (dcu.ie)
Finite element models o f thin and thick strut stents were developed and the stents were deployed in various stenosed vessel geometries such that the stresses induced within the stented vessels by the two stents could be compared. (dcu.ie)
Brachytherapy with both gamma and beta sources has been found to result in improved outcome with less angiographic restenosis and decreased target vessel revascularization. (elsevierpure.com)
Background: Benefits of drug-eluting stents (DES) in percutaneous coronary intervention (PCI) are greatest in those at the highest risk of target vessel revascularization (TVR). (ku.edu)
Doctors deliver coronary stents by threading a slender tube (catheter) through a vessel in the wrist or upper thigh all the way up to the heart. (harvard.edu)

Only physicians who have received adequate training should perform implantation of the stent. (medtronic.com)
The risks and benefits of the stent implantation should be assessed for patients with a history of severe reaction to contrast agents. (medtronic.com)
Percutaneous coronary intervention (PCI) was then undertaken, which, due to the complex nature of the stenosis, required implantation of two drug-eluting stents (DESs) (Xience V, Abbot, Temecula, Calif, USA) on both bifurcations. (hindawi.com)
Dual Antiplatelet Therapy Guided by CYP2C19 Polymorphisms after Implantation of Second-Generation Drug-Eluting Stents for Management of Acute Coronary Syndrome. (cdc.gov)

The higher restenosis rate of the thicker strut stent, reported in the ISAR-STEREO clinical study, was found to be the result of the higher luminal gain achieved by the thicker strut stent, due to the lower recoil of the stent structure when both stents were expanded to the same initial lumen diameter. (dcu.ie)

BACKGROUND: Previous studies have shown conflicting results about the relationship between baseline C-reactive protein (CRP) and restenosis after stenting with bare metal stent (BMS). (unicatt.it)
Originally, stents were made of bare metal. (harvard.edu)

We aimed to investigate whether peri-procedural administration of corticosteroids or the use of thinner strut cobalt alloy stents would reduce rates of binary angiographic restenosis (BAR) after PCI. (ox.ac.uk)
METHODS: We assessed the association between serum CRP and angiographic restenosis after BMS by meta-analysis. (unicatt.it)
An inverse random weighted meta-analysis was performed by entering the logarithm of the odds ratio (OR) of angiographic restenosis with its standard error for each study. (unicatt.it)
Higher preprocedural CRP levels were a significant predictor of angiographic restenosis: OR 1.59, 95% confidence interval 1.21-2.07, P=.001. (unicatt.it)
CONCLUSIONS: Among patients with coronary artery disease, undergoing percutaneous coronary intervention with BMS, higher baseline CRP levels are associated with higher risk of angiographic restenosis. (unicatt.it)

Subsequent stent restenosis or occlusion may require repeat catheter-based treatments (including balloon dilatation) of the arterial segment containing the stent. (medtronic.com)

The long-term outcome following repeat catheter-based treatments of previously implanted endothelialized stents is not well characterized. (medtronic.com)

Angiographically, restenosis is defined dichotomously as a luminal narrowing of more than 50% in the follow-up angiography, which occurs as a consequence of arterial damage with subsequent neointimal tissue proliferation [ 1 ]. (hindawi.com)
Several pathogenic mechanisms have been associated with restenosis development, among which we can find elastic recoil of the vessels, arterial remodeling, and neointimal hyperplasia. (hindawi.com)
Several reports in the literature have focussed on the formulation of the modelling approach applied to highly idealized arterial and stent geometries. (springer.com)
The finite element studies successfully identified differences between the mechanical loading of the arterial tissue in the vessels stented with the two different stents. (dcu.ie)
Stents work on a simple principle: a balloon expands the stent to support the arterial wall and is then deflated and removed. (technologyreview.com)
Subsequent stent blockage may require repeat dilatation of the arterial segment containing the stent. (bostonscientific.com)

Additionally, the safety and effectiveness of using atherectomy devices with the stent have not been established. (medtronic.com)

We report on an approach for validation of an in silico 3D model of in-stent restenosis in porcine coronary arteries and illustrate this approach by comparing the modelling results to in vivo data for 14 and 28 days post-stenting. (springer.com)
Today, restenosis in coronary arteries afflicts less than 10 percent of patients thanks to the development of the drug-eluting stent (DES), which slowly releases a drug that inhibits the growth of scar tissue. (technologyreview.com)
When I had a heart attack late last year, I got a stent in one of my coronary arteries. (harvard.edu)

Conclusions: DES use in the U.S. varies widely among physicians, with only modest correlation to patients' risk of restenosis. (ku.edu)
Less DES use among patients with low risk of restenosis has the potential for significant cost savings for the US healthcare system, while minimally increasing restenosis events. (ku.edu)
Genetic risk of restenosis after percutaneous coronary interventions in the era of drug-eluting stents. (cdc.gov)

Coronary artery restenosis is an important side effect of percutaneous coronary intervention. (springer.com)
This narrowing is often corrected by deploying a stent in the affected artery to keep it open and maintain blood flow. (springer.com)
In-stent restenosis is the renarrowing o f the artery lumen within a stent predominantly due to excessive growth of neointimal hyperplasia. (dcu.ie)
The stress analyses were used to determine the level of vascular injury caused to the artery by different strut thickness stents. (dcu.ie)
The US Food and Drug Administration (FDA) has approved Medtronic's IN.PACT Admiral drug-coated balloon as a treatment for in-stent restenosis in patients with peripheral artery disease. (vascularnews.com)
3, 4, 5] This anatomic region is characterized by a high biomechanical stress, which consequently negatively affects patency rates associated with the popliteal artery bypass procedures and imposes technical limitations on endovascular stenting, in that biomechanical stress may lead to stent fractures. (medscape.com)
Medicare covers PTA of the carotid artery concurrent with the placement of an FDA-approved carotid stent and an FDA-approved or cleared embolic protection device for an FDA-approved indication when furnished in accordance with FDA-approved protocols governing post-approval studies. (cms.gov)
Coverage is limited to procedures performed using FDA-approved carotid artery stenting systems and FDA-approved or cleared embolic protection devices. (cms.gov)
To study the frequency of In-Stent Restenosis and its treatment in patients undergoing Percutaneous Coronary Intervention for coronary artery disease. (pafmj.org)
Left Anterior Descending was the commonest coronary artery that developed In-Stent Restenosis, followed by Right Coronary Artery and Left Circumflex respectively. (pafmj.org)
Stent placement should only be performed at hospitals where emergency coronary artery bypass graft surgery can be readily performed. (medtronic.com)
Then a stent containing another balloon is inserted into the artery. (technologyreview.com)
In about 30 percent of cases, scar tissue formed around the site of the injury, causing the artery to close again, a setback called restenosis. (technologyreview.com)
Once the catheter reaches the area in the artery narrowed by fatty plaque, the balloon inflates and deploys the stent. (harvard.edu)
The stent holds the artery open, restoring blood flow. (harvard.edu)
Known as restenosis, the process can re-block blood flow through the artery, causing chest pain (angina) and, in some cases, a heart attack. (harvard.edu)
The artery can be reopened with a procedure similar to the original stent placement, although doctors sometimes need to use a tiny drill or laser to cut through the obstruction. (harvard.edu)
Patients with diabetes mellitus have more extensive coronary artery disease, more disease progression, and restenosis. (lu.se)

In-stent restenosis is clinically challenging and accounts for about 10% of all percutaneous coronary interventions. (medscape.com)
The SSTARS (STeroids and Stents Against Re-Stenosis) Trial: Different stent alloys and the use of peri-procedural oral corticosteroids to prevent in-segment restenosis after percutaneous coronary intervention. (ox.ac.uk)
BACKGROUND: Stent design and technological modifications to allow for anti-proliferative drug elution influence restenosis rates following percutaneous coronary intervention (PCI). (ox.ac.uk)
Objective:We examined the effects of peri-procedural intensive glycemic control (IGC) during early percutaneous coronary intervention (PCI) on restenosis rate in hyperglycemic patients with ST-segment elevation myocardial infarction (STEMI).Research Design and Methods:A total of 165 hyperglycemic patients (glucose ≥140 mg/dl) with first STEMI undergoing PCI were studied. (unisa.it)
BACKGROUND: In-stent restenosis (ISR) remains one of the main limitations for percutaneous coronary intervention of unprotected distal left main (UDLM). (unisr.it)
Thus new improvements to balloons and stents are always necessary to achieve the best results from percutaneous coronary intervention (PCI). (scirp.org)

In addition, failure to deploy the stent optimally at the time of the initial placement may result in increased restenosis. (elsevierpure.com)
Whether increased Lp-PLA2 level is associated with re-stenosis after stent-placement is unclear. (biomedcentral.com)
Totally 326 participants eligible for stent-placement were enrolled and divided into two groups according to baseline Lp-PLA2 levels (named normal and elevated groups). (biomedcentral.com)
Owing to the significant and unequivocal implications of Lp-PLA2 on the initiation and progression of atherosclerosis and CAD, we speculated that increased plasma level of Lp-PLA2 at baseline might contribute to re-stenosis in patients with stent placement. (biomedcentral.com)
After angiographic evaluation, patients diagnosed as significant CHD and eligible for stent-placement were enrolled after written informed consent was obtained. (biomedcentral.com)

The safety and effectiveness of the stent have not been established in the cerebral, carotid, or peripheral vasculature. (medtronic.com)

Today, the IN.PACT Admiral drug-coated balloon has demonstrated consistent outcomes across all patient morphologies, and it is the only drug-coated balloon approved to treat patients with in-stent restenosis in the USA. (vascularnews.com)

Association of CYP2C19*2 polymorphism with clopidogrel response and 1-year major adverse cardiovascular events in a multiethnic population with drug-eluting stents. (cdc.gov)

In-stent restenosis and atherosclerosis in a human saphenous vein graft. (ox.ac.uk)

Stenting of symptomatic myocardial bridges is a therapeutic option with documented good short-term outcome. (minervamedica.it)
The ISAR-STEREO Trial specifically assessed the effect o f strut thickness on restenosis outcome and found that for the same stent design, a thinner strut stent was associated with a significant reduction o f angiographic and clinical restenosis compared to the same stent with a thicker strut. (dcu.ie)
In-stent restenosis was positively associated with mean plasma glucose levels as well as oxidative stress and inflammatory markers during the insulin infusion period.Conclusions:In hyperglycemic patients with STEMI, optimal peri-procedural glycemic control by reducing oxidative stress and inflammation may improve the outcome after PCI. (unisa.it)
Impact of CYP2C19 polymorphism on clinical outcome following coronary stenting is more important in non-diabetic than diabetic patients. (cdc.gov)
CYP2C19 loss-of-function alleles are not associated with clinical outcome of clopidogrel therapy in patients treated with newer-generation drug-eluting stents. (cdc.gov)

Moreover, the uptake of percutaneous intervention in larger numbers of patients with increasingly complex lesion characteristics and disease comorbidities means that the number of patients presenting with restenosis remains considerable in absolute terms [ 3 ]. (hindawi.com)
Target lesion failure may be more frequent when IVL is performed for the treatment of ISR due to calcium-mediated stent under expansion. (frontiersin.org)

Myocardial infarction was significantly less common with DES in patients who received only one stent RR, 0.80 (95% CI, 0.66-0.96). (lu.se)

Stent Restenosis Study Investigators. (hopkinsmedicine.org)

Therefore, it is proposed that the use of preclinical testing tools, such as finite element modelling, could be used to predetermine the deployment protocol and optimum luminal gain of a particular stent design in order to minimise the mechanical stimuli for in-stent restenosis. (dcu.ie)
ISR was assessed by finding ≥50% narrowing of the stent or peri-stent segments luminal diameter at follow-up coronary angiography. (ijisrt.com)

With the introduction of drug-eluting stents (DESs), the incidence of ISR has markedly decreased. (ijcdw.org)
DES reduced the incidence of in-stent restenosis. (scirp.org)

Carotid arteries of cholesterol fed rabbits underwent stenting or balloon injury in the presence of low or normal flow. (edu.au)

Further stenting analyses, however, found that the thicker strut stent resulted in a lower percentage of volume stressed at high levels compared with the thinner strut stent when it was expanded to the same final lumen diameter. (dcu.ie)

There was statistically significant association (p-value=0.02) between stent length and frequency of In-Stent Restenosis and it was commonest in stents longer than 30 mm. (pafmj.org)

History of diabetes mellitus and greater stent length were major risk factors in developing In-Stent Restenosis in our study. (pafmj.org)

The patient had been stented on both ICA , left side with dual layer micro mesh stent and right side with an open cell design, Protege, Medtronic. (vascupedia.com)

Clinical studies have found that stent design is a key determinant in the propensity o f stents to cause restenosis, indicating a vital link between the biomechanics o f stents and the development of the disease. (dcu.ie)
When drug-eluting stents (DES) are used outside the specified Indications for Use , patient outcomes may differ from the results observed in the RESOLUTE pivotal clinical trials. (medtronic.com)
pharmacological stents were implanted in almost all cases, and angiographic and clinical success rates were high. (bvsalud.org)

When a patient needs to have a stent placed in one of the vessels around their heart, it is important that that stent stay open to keep blood flowing to the heart. (wikipedia.org)
balloon) and markedly attenuated by PDTC, and that c-jun is an important mediator of flow-dependent restenosis in balloon-injured but not stented vessels. (edu.au)

Dual antiplatelet therapy with aspirin plus thienopyridines has become the standard treatment of patients undergoing coronary stenting. (hindawi.com)

Until now physicians have had limited treatment options to address patients with in-stent restenosis. (vascularnews.com)
Coronary In-Stent Restenosis: Predictors and Treatment. (nih.gov)
The place of rotablator for treatment of in-stent restenosis. (nih.gov)
We report a case of clopidogrel-induced bone marrow toxicity manifesting with severe neutropenia in a patient treated with multiple coronary stents and provide suggestions for an alternative treatment. (hindawi.com)

Tizón-Marcos H, Rodríguez-Costoya I, Tevar C, Vaquerizo B. Intracoronary lithotripsy for calcific neoatherosclerotic in-stent restenosis: a case report. (upf.edu)
In-stent restenosis due to calcific neoatherosclerosis was observed by intracoronary imaging during the intervention. (upf.edu)

The stresses were examined at the end o f stent deployment, to determine the mechanical stimuli for acute damage, and again at stent unloading, to determine the long term stimuli for in-stent restenosis. (dcu.ie)
CHA2DS2-VASc Score, In-Stent Restenosis, Acute Coronary Syndrome. (ijisrt.com)

Stent fracture was observed in 5 stents through 5 years. (bvsalud.org)

This study aims to demonstrate the impact of main-branch ISR (MB-ISR) on mortality and to clarify the optimal strategy.METHODS: Between 2002 and 2008, 482 consecutive UDLM patients treated with drug eluting stent (sirolimus and paclitaxel) were evaluated.RESULTS: During follow-up period (median 52.6 months), MB-ISR occurred in 29, SB-ISR in 65, and MB/SB-ISR in 24. (unisr.it)

Although a reduction in the percentage of subjects developing restenosis has been observed at the same time PCA has evolved, in-stent restenosis (ISR) continues to be one of the main complications in patients undergoing this procedure [ 2 ]. (hindawi.com)
Therefore, patients with stents must take medications after the procedure to help maintain that blood flow. (wikipedia.org)

Different components of DES which include the polymers, drugs and the stents underwent progressive evolution, and these led to development of new generations of DES with variable types of drugs and polymers to fully absorbable stents. (scirp.org)

Anatomy22

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Treat in-stent restenosis2

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