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  • research
  • To fulfill this intent, a diverse group of 13 national and international specialists were enlisted to serve on a Human Stem Cell Research (HSCR) Advisory Committee established to advise the Department in the development of statewide guidelines for human stem cell research and the update of these guidelines. (ca.gov)
  • hematopoietic stem
  • In 2006 a total of 50,417 first hematopoietic stem cell transplants were reported as taking place worldwide, according to a global survey of 1327 centers in 71 countries conducted by the Worldwide Network for Blood and Marrow Transplantation. (wikipedia.org)
  • somatic
  • While hESC are derived from a developing embryo, iPSC are generated with forced expression of key transcription factors to convert adult somatic cells to ESC-like cells, a process termed reprogramming. (springer.com)
  • scientists
  • Recently named the 2018 Science Magazine "Breakthrough of the Year," single cell sequencing allows scientists to retrace the steps that cells took during development, one cell at a time. (isscr.org)
  • Pennington Biomedical Research Center scientists have found a way to convert stem cells in human fat to human bone cells when transplanted into a mouse. (wired.com)
  • Therefore, scientists can use stem cells found in certain places in the body, such as the bone marrow, and code them for whatever type of cell is needed. (shsu.edu)
  • Scientists believe that stem cell research can be used to treat medical conditions including Parkinson's disease, spinal cord injury, stroke, burns, heart disease, diabetes, osteoarthritis and rheumatoid arthritis. (cnn.com)
  • The nonhuman cell-surface sialic acid can compromise the potential uses of the stem cells in humans, say scientists at the University of California, San Diego. (wired.com)
  • therapy
  • For the medical therapy, see Stem cell therapy . (wikipedia.org)
  • Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. (wikipedia.org)
  • this is the only form of stem-cell therapy that is widely practiced. (wikipedia.org)
  • Another stem-cell therapy called Prochymal , was conditionally approved in Canada in 2012 for the management of acute graft-vs-host disease in children who are unresponsive to steroids. (wikipedia.org)
  • Cancer stem cells (CSCs) are thought to play an important role in tumor recurrence and drug resistance, and present a major challenge in cancer therapy. (biomedcentral.com)
  • It is widely believed that targeting the tumour-initiating cancer stem cell (CSC) component of malignancy has great therapeutic potential, particularly in therapy-resistant disease. (biomedcentral.com)
  • The initiation and progression of malignant tumors is driven by distinct subsets of tumor-initiating or cancer stem-like cells (CSCs) which develop therapy/apoptosis resistance and self-renewal capacity. (biomedcentral.com)
  • An article collection in Stem Cell Research & Therapy . (biomedcentral.com)
  • Dr Ralph Holme, director of biomedical research at The Royal National Institute for Deaf People (RNID), said: "Stem cell therapy for hearing loss is still some years away, but this research is incredibly promising and opens up exciting possibilities by bringing us closer to restoring hearing in the future. (www.nhs.uk)
  • Research
  • Stem cell research" redirects here. (wikipedia.org)
  • For the journal, see Stem Cell Research (journal) . (wikipedia.org)
  • Research into stem cells grew out of findings by Ernest A. McCulloch and James E. Till at the University of Toronto in the 1960s. (wikipedia.org)
  • The ISSCR advocates worldwide for ethical stem cell research and its translation to the clinic. (isscr.org)
  • Find the resources and connections you need to further drive your career and skills in the ever-changing and exciting field of stem cell research. (isscr.org)
  • The International Society for Stem Cell Research (ISSCR) is an independent nonprofit organization and the voice of the stem cell research community. (isscr.org)
  • The ISSCR was founded in 2002 to foster the exchange of information on stem cell research and now claims more than 4,100 members worldwide. (isscr.org)
  • Accelerating cures for the major diseases of our time through stem cell research. (nyscf.org)
  • The New York Stem Cell Foundation combines the depth of a highly focused research institute with the breadth of a wide-ranging philanthropic organization. (nyscf.org)
  • Since its establishment in 2005, NYSCF has invested over $200 million in stem ‚Äčcell research and continues to conduct the most advanced stem cell research internationally, both in its own laboratory in New York City, and also in collaboration with major medical research and leading academic institutions around the world. (nyscf.org)
  • Stem cell research in the United States remains at the center of controversy and was a hotly debated topic during the recent election. (tinnitusformula.com)
  • There is much more research to be done toward developing clinically applied techniques for the treatment of hearing loss with stem cells. (tinnitusformula.com)
  • Research is underway to develop various sources for stem cells, as well as to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes and heart disease , among others. (wikipedia.org)
  • Research has been conducted on the effects of stem cells on animal models of brain degeneration , such as in Parkinson's , Amyotrophic lateral sclerosis , and Alzheimer's disease . (wikipedia.org)
  • Signi?cant advances in stem cell research and their potentials for therap- tic applications have attracted the attention of the scienti?c community and captured the imagination of society as a whole. (springer.com)
  • Since 1998, extensive research endeavours have been devoted to the study of both embryonic and adult stem cells. (springer.com)
  • This makes them less suitable for establishing cell lines for research. (slideshare.net)
  • Two basic factors in stem cell research are the difference between embryonic stem cells that proliferate for a year or more in the laboratory without specializing or differentiating into different types of cells and adult stem cells that cannot proliferate without differentiating. (news-medical.net)
  • Stem cell research focuses on embryonic stem cells and adult stem cells. (cnn.com)
  • 1998 - President Bill Clinton requests a National Bioethics Advisory Commission to study the question of stem cell research. (cnn.com)
  • 1999 - The National Bioethics Advisory Commission recommends that the government allow federal funds to be used to support research on human embryonic stem cells. (cnn.com)
  • The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. (springer.com)
  • WASHINGTON - The human embryonic stem cells available for research are contaminated with nonhuman molecules from the culture medium used to grow the cells, researchers report. (wired.com)
  • We eat animal products and drink milk all the time and get this acid into our cells, and yet we are not always suffering from raging autoimmune disease,' said Battey, who was not part of the research team. (wired.com)
  • Even though the priest at the parish JD and I have been attending reminded us to vote against Stem Cell Research, I'm all for it. (glamour.com)
  • That said, where do you stand on Stem Cell Research? (glamour.com)
  • Yesterday, the Garden State rejected a proposal by Gov. Jon Corzine to borrow up to $450 million to fund stem cell research initiatives over the next 10 years. (glamour.com)
  • Follow this link for frequently asked questions about stem cell research. (glamour.com)
  • A lab technician conducts research for stem cell-based treatments for heart attack victims in 2005. (orlandosentinel.com)
  • This research has shown that stem cells can be isolated from tissue from part of the human foetal inner ear (the cochlear), and can then be grown in the laboratory so that they develop into cells with hair cell and nerve cell-like characteristics. (www.nhs.uk)
  • Before carrying out this latest research, the researchers had already found that stem cells are present in the foetal human inner ear, but had not yet developed a technique for extracting these. (www.nhs.uk)
  • chemotherapy
  • After the child receives chemotherapy and/or radiation, the stem cells are thawed and put back into the child's body. (kidshealth.org)
  • Induction chemotherapy to reduce cancer cells in the body as much as possible. (angelfire.com)
  • The induction chemo also referred to as salvage chemotherapy is done to establish whether the patient's cancer is responsive to treatment or not and because the cancer must be put into remission (usually by chemotherapy) before the stem cell harvesting can be done. (angelfire.com)
  • High dose chemotherapy (HDC) is a lethal dose of chemotherapy, enough chemo to kill off virtually all existing blood cells and the blood cell producing cells in the marrow. (angelfire.com)
  • The patient is then treated with high-dose chemotherapy with or without radiotherapy with the intention of eradicating the patient's malignant cell population at the cost of partial or complete bone marrow ablation (destruction of patient's bone marrow's ability to grow new blood cells). (wikipedia.org)
  • endothelial cells
  • ESCs will eventually produce endothelial cells (ECs), which create the thin-walled endothelium that lines the inner surface of blood vessels and lymphatic vessels. (wikipedia.org)
  • Vitro
  • This breakthrough and the subsequent generation of specialized human cells in vitro led to a paradigm shift within the sci- ti?c community, which transformed this specialized endeavour from a topic of scienti?c interest to a line of investigation with the potential to generate cells - pable of treating serious ailments, including diabetes, cardiovascular diseases and neurodegenerative disorders. (springer.com)
  • cancer cells
  • Sometimes, an upside of graft-versus-host disease is that the newly transplanted cells recognize the body's cancer cells as different or foreign, and actually work to fight them. (kidshealth.org)
  • isolate
  • They have developed a technique to routinely isolate and propagate these stem cells in an artificial environment. (tinnitusformula.com)
  • In this study, the researchers wanted to isolate these cells and look at whether they could be grown in the laboratory and had the potential to develop into functioning hair cells and nerve cells. (www.nhs.uk)
  • sensory hair cells
  • More than 80% of all cases of hearing loss can be attributed to the degeneration and death of sensory hair cells. (tinnitusformula.com)
  • Once the researchers confirmed that they had isolated stem cells, they investigated how long they could keep these cells alive in the laboratory, and whether the cells had the ability to develop into the sensory hair cells and nerve cells found in the ear. (www.nhs.uk)
  • The cells that developed were examined to see whether they looked like sensory hair cells or nerve cells, and whether they expressed genes and proteins that were typical of these types of cells. (www.nhs.uk)
  • treatments
  • After the harvesting of the stem cells, the patient must then undergo very high dose treatments to kill any disease that might be left in the body. (angelfire.com)
  • This laboratory study tried to identify human stem cells that could potentially be used in treatments for deafness. (www.nhs.uk)
  • undergo
  • For instance, a child who is about to undergo cancer treatment will have his or her own stem cells removed (harvested) and frozen for later use. (kidshealth.org)
  • In the second Aim, the temporal presentation of the peptides will be investigated by introducing linkers that undergo cell-mediated proteolysis of the peptides from the HA hydrogels. (upenn.edu)
  • Regulation
  • Quantifying the size, mechanical inhomogeneity, and biological response among tissue micro-domains is important because this is the length scale that governs cell mechanotransduction, and therefore regulation of tissue homeostasis and disease progression. (upenn.edu)
  • humans
  • A blastocyst is an early stage embryo-approximately four to five days old in humans and consisting of 50-150 cells. (slideshare.net)
  • Last summer, more than half the members of the Senate urged easing limits on new cell lines, noting that potential contamination could make available lines use for humans uncertain. (wired.com)
  • haematopoietic
  • Not so long ago, the study of most stem cells, other than those that regenerated the haematopoietic system, was rather obscure and limited to a relatively small number of researchers and laboratories. (springer.com)
  • Autologous HSCT requires the extraction ( apheresis ) of haematopoietic stem cells (HSC) from the patient and storage of the harvested cells in a freezer. (wikipedia.org)