Stem clone embryo. Medical search. Frequent questions

Then, in 2013, he created human embryos through cloning, as a way of creating patient-specific stem cells. (technologyreview.com)

Therapeutic cloningin contrast to reproductive cloning, intended to create a babywould produce the stem cells needed to treat diabetes, paralysis and other currently incurable conditions. (scientificamerican.com)
When an embryo like this is implanted into a uterus, as with Dolly, the process is called reproductive cloning. (nih.gov)
Scientists at the University of Yamanashi in Kofu, Japan, have developed a new method that uses freeze-dried somatic cells-cells other than reproductive cells-to clone mice. (genengnews.com)
It may be that "therapeutic cloning" cannot be made to work without conducting the "reproductive cloning" that almost everyone condemns - placing embryos in women's wombs, in this case in order to abort them later for their more developed tissues. (thenewatlantis.com)
6. Scientists, philosophers, politicians and humanists agree on the need for an international ban on reproductive cloning. (lifeissues.net)
2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Some seek to ban all cloning, while others oppose "only" reproductive cloning. (capitalismmagazine.com)
Any attempt to ban human cloning technology should be rejected permanently, because cloning-therapeutic and reproductive-is morally good. (capitalismmagazine.com)
The same virtue applies to reproductive cloning-which, despite the ridiculous, horror-movie scenarios conjured up by its opponents, would simply result in time-separated twins just as human as anyone else. (capitalismmagazine.com)
Once it becomes safe, reproductive cloning will have legitimate uses for infertile couples and for preventing the transmission of genetic diseases. (capitalismmagazine.com)
At stake with reproductive cloning is not only whether you can conceive a child who shares your genetic makeup, but whether you have the right to improve the genetic makeup of your children: to prevent them from getting genetic diseases, to prolong their lifespan or to improve their physical appearance. (capitalismmagazine.com)
Since that time, the discussion has turned towards the possibilities of cloning human beings either for research ("therapeutic") or reproductive purposes, and even as a potential means for organ farming. (cbhd.org)
Ethical issues specific to human cloning include: the safety and efficacy of the procedure, cloning for destructive embryonic stem cell research, the effects of reproductive cloning on the child/parent relationship, and the commodification of human life as a research product. (cbhd.org)
Though both seek a ban on what is being called 'reproductive' cloning--in which a clonal human embryo is implanted in a woman with the intent that a cloned human being will be born--they differ dramatically with respect to what is being termed 'therapeutic' cloning. (cbhd.org)
To achieve this end, we believe that a comprehensive ban prohibiting both 'reproductive' and 'therapeutic' cloning is needed. (cbhd.org)
I. The overwhelming consensus in this country that human reproductive cloning should not be permitted necessitates a ban on both reproductive and 'therapeutic' cloning. (cbhd.org)
An overwhelming majority of scientists, lawyers, health care professionals, ethicists and the general public has spoken out strongly against creating a human baby via what is being termed 'reproductive cloning. (cbhd.org)
4 While most U.S. citizens support a ban on the reproductive cloning of human beings, they may or may not support a ban on 'therapeutic' cloning. (cbhd.org)
Yet, to enact a ban on the former while simultaneously permitting the latter would almost certainly result in instances of both reproductive and 'therapeutic' cloning. (cbhd.org)
First, if a ban only on reproductive cloning were adopted, enforcement would require the legally mandated destruction of human embryos created via cloning. (cbhd.org)
That is, if it were legal to create clonal embryos for 'therapeutic'--but not for reproductive--purposes, the demise of these embryos would be required in order to prevent the illegal practice of reproductive cloning from occurring. (cbhd.org)
The National Academy of Sciences, while supporting (2001) such so-called therapeutic or research cloning, has opposed (2002) the cloning of humans for reproductive purposes, deeming it unsafe, but many ethicists, religious and political leaders, and others have called for banning human cloning for any purpose. (infoplease.com)
Cloning technology, however, is perceived as having the potential for reproductive cloning, which raises serious ethical and moral concerns. (who.int)
This is reproductive cloning, and can in theory be applied to any species of mammals, including humans. (who.int)
Reproductive cloning in humans and therapeutic cloning in primates: is the ethical debate catching up with the recent scientific advances? (bmj.com)

In a concurrent article in the January Scientific American, the researchers explained that their results could "represent the dawn of a new age in medicine by demonstrating that the goal of therapeutic cloning is within reach. (scientificamerican.com)
Researchers have been hoping to harness the therapeutic potential of cloning ever since the cloning of Dolly the sheep in 1997. (nih.gov)
In another strategy, called therapeutic cloning, the embryo can instead be used to create stem cells that are genetically identical to a patient. (nih.gov)
Therapeutic cloning has garnered a great deal of attention over the past few years, but until now it had only been achieved in the mouse. (nih.gov)
Their report, published in the same issue of the journal, confirms that therapeutic cloning has now been accomplished in primates for the first time. (nih.gov)
Although this study proves that the therapeutic cloning of primates is possible, there are still many hurdles to be overcome. (nih.gov)
Despite this apparent setback, the field of embryonic stem cell research and therapeutic cloning remains incredibly promising as demonstrated by some of our nation's leading scientists," says Daniel Perry, president of the Coalition for the Advancement of Medical Research. (thenewatlantis.com)
After years of touting so-called "therapeutic cloning" - the idea that stem cells from cloned blastocysts would supply every sick person with his own "biological repair kit" - no one has achieved even the first step toward making this medical dream a reality. (thenewatlantis.com)
Most Americans, and most legislators, probably assume that there are at least established animal models for the use of ESCs from "therapeutic cloning. (thenewatlantis.com)
Some studies published by Advanced Cell Technology and others have been touted as showing benefits from stem cells harvested from cloned animal embryos - but in each case, the study had to achieve its therapeutic goal by implanting the embryo in an animal's uterus and growing it to the fetal stage, then killing the fetus for more developed fetal stem cells. (thenewatlantis.com)
Such "fetus farming" is now apparently seen by some researchers as the new paradigm for human "therapeutic cloning," and some state laws on cloning (e.g. (thenewatlantis.com)
2 The multiple therapeutic achievements that have been demonstrated using adult stem cells, and the promise they hold for other diseases, such as neurodegenerative disorders or diabetes, make efforts to support this fruitful avenue of investigation an urgent matter. (lifeissues.net)
Embryonic stem-cell experiments have not yet produced a single unqualified therapeutic success, not even in animal models. (lifeissues.net)
4. The so-called "therapeutic cloning", which would be better called "research cloning" because we are still far from therapeutic applications, has been proposed in order to avert the potential immune rejection of embryonic stem cells derived from a donor other than the host. (lifeissues.net)
Moreover, a non-human primate model of cloning, which would be necessary in order to conduct experiments to establish safety before attempting therapeutic experiments in human beings, has yet to be developed. (lifeissues.net)
5. The health benefits of therapeutic cloning are hypothetical, in as much as the method itself remains mainly a hypothesis. (lifeissues.net)
Indeed, even putting aside fundamental ethical considerations other than the patient's expectations, the present state of "therapeutic cloning" precludes, now and in the near future, any clinical application. (lifeissues.net)
Consider first therapeutic cloning, which opponents perversely condemn as "anti-life. (capitalismmagazine.com)
Senator Sam Brownback, who has sponsored a Congressional ban on all cloning, says therapeutic cloning is "creating human life to destroy [it]. (capitalismmagazine.com)
In fact, therapeutic cloning is a highly pro -life technology, since cloned embryos can be used to extract medically potent embryonic stem cells. (capitalismmagazine.com)
Opponents of therapeutic cloning know all this, but are unmoved. (capitalismmagazine.com)
This is because their fundamental objection is not that therapeutic cloning is antilife, but that it entails "playing God"-i.e., remaking nature to serve human purposes. (capitalismmagazine.com)
An Australian ban on therapeutic cloning was lifted in December 2006 after a long debate in Federal parliament. (bioedge.org)
Indeed, if clonal human embryos were created in the laboratory for 'therapeutic' purposes, the mandate that they not be implanted or otherwise allowed to progress toward birth would prove very difficult to defend. (cbhd.org)
Therapeutic cloning possesses enormous potential for revolutionizing medical and therapeutic techniques. (who.int)
This is therapeutic cloning. (who.int)

But the mismatch also raises the possibility that the embryonic stem-cell lines were not cloned from the stated patients. (bioedonline.org)
Researchers reported in Nature on November 22, 2007, that they successfully isolated 2 embryonic stem cell lines from cloned embryos made using cells from the skin of an adult rhesus macaque. (nih.gov)
The team that isolated the embryonic stem cell lines was led by Dr. Shoukhrat Mitalipov at Oregon Health and Science University in Portland. (nih.gov)
The stem cells, the researchers showed, could turn into heart or nerve cells in the laboratory, and had other characteristics of established embryonic stem cell lines. (nih.gov)
15. Generation of embryonic stem cell lines from mouse blastocysts developed in vivo and in vitro: relation to Oct-4 expression. (nih.gov)
19. Establishment of human embryonic stem cell lines from frozen-thawed blastocysts using STO cell feeder layers. (nih.gov)
Our data reveal that although some DNA abnormalities are observed in the process, freeze dried somatic cell nuclei can be used to generate blastocysts by nuclear transfer, and embryonic stem cell lines derived from these blastocysts yield donor nuclei that are capable of producing healthy, fertile cloned mice," the authors noted. (genengnews.com)
They adapted the procedure for somatic cell nuclear transfer to generate embryos (blastocysts) and stable embryonic stem cell lines. (genengnews.com)
After nuclear transfer, we produced cloned blastocysts from freeze-dried somatic cells, and established nuclear transfer embryonic stem cell lines," the authors noted. (genengnews.com)
The NIH has published final guidelines on the allowability of Federal funds to be used for research on existing human embryonic stem cell lines. (nih.gov)

To date, three previous reports of editing human embryos were all published by scientists in China. (technologyreview.com)
In altering the DNA code of human embryos, the objective of scientists is to show that they can eradicate or correct genes that cause inherited disease, like the blood condition beta-thalassemia. (technologyreview.com)
But other scientists confirmed the editing of embryos using CRISPR. (technologyreview.com)
Plans to allow British scientists to create human-animal embryos are expected to be approved tomorrow by the government's fertility regulator. (physiciansforlife.org)
The Human Fertilisation and Embryology Authority published its long-awaited public consultation on the controversial research yesterday, revealing that a majority of people were 'at ease' with scientists creating the hybrid embryos. (physiciansforlife.org)
The consultation papers were released ahead of the authority's final decision on the matter, which will mark the end of almost a year of intense lobbying by scientists and a fervent campaign by organisations opposed to research involving embryonic stem cells. (physiciansforlife.org)
In December, the government sparked a revolt by scientists, patient groups and medical researchers when it published a white paper containing proposals to outlaw almost all research into animal-human embryos. (physiciansforlife.org)
The British government is set to make a decision on 5Sept07 about whether scientists can engage in human and animal cloning that fuses the two together. (physiciansforlife.org)
Weizmann Institute researcher Jacob Hanna said the scientists' creation 'is really a textbook image of a human day-14 embryo,' something that 'hasn't been done before. (lifesitenews.com)
The truth surely lies somewhere between these extremes: the scandal implicates far more than a few Korean scientists, but it does not undermine science in general, unless one foolishly equates human cloning with all of science. (thenewatlantis.com)
T he first obvious conclusion, as noted by the Washington Post , is that "the highly touted field of embryonic stem cell research is years behind where scientists thought it was. (thenewatlantis.com)
Ever since speculation over the healing potential of human embryonic stem cells began circulating after scientists isolated them in 1998, I have wondered what I would do if scientists ever extracted a cure for my child's incurable disease from tiny human lives like the one I had cherished. (christianitytoday.com)
I set out to find answers by talking to two stem-cell scientists about the ethics of their work. (christianitytoday.com)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
In a huge breakthrough for medical progress, scientists from South Korea have finally created a cloned human embryo and extracted its stem cells-a feat that makes life-saving embryonic stem-cell treatments that much closer to reality. (capitalismmagazine.com)
Chinese scientists have successfully created chimeric embryos containing a combination of human and pig cells. (bioedge.org)
South Korean scientists announced in 2004 that they had cloned 30 human embryos, but an investigation in 2005 determined that the data had been fabricated. (infoplease.com)
The concept of human cloning has long been in the imagination of many scientists, scholars and fiction writers [1]. (who.int)
To research more, scientists need more human embryonic stem cells, which, of course, means more destrution of embryos to obtain the stem cells. (prolifelouisiana.org)
The use of embryos from In Vitro are dependent on the donation of these embryos by the parents to scientists. (prolifelouisiana.org)
This limits the number of embryos scientists can acquire. (prolifelouisiana.org)
By Wesley J. Smith When George W. Bush put federal funding restrictions on embryonic stem cell research, the media and "the scientists" screamed that he was "anti-science" and that he was destroying the "only hope" for CURES! (nationalrighttolifenews.org)
Cardin adds, "Stem cell research has the potential to help scientists make tremendous breakthroughs in medical innovation. (issues2000.org)

carrying out cryopreservation of mouse embryos and sperm to preserve valuable mouse lines. (nih.gov)

A person familiar with the research says "many tens" of human IVF embryos were created for the experiment using the donated sperm of men carrying inherited disease mutations. (technologyreview.com)

Selective embryo destruction for in vitro fertilization? (medscape.com)
Laboratory experiments in in vitro fertilization of human eggs led in 1993 to the "cloning" of human embryos by dividing such fertilized eggs at a very early stage of development, but this technique actually produces a twin rather than a clone. (infoplease.com)
It is prohibited by Louisiana Law to experiment on human embryos developed through In Vitro Fertilization. (prolifelouisiana.org)
Today, this technique continues to form the foundation for research on mammalian embryos, including technologies such as transgenic engineering, embryonic stem cell therapy, human in vitro fertilization, mammalian cloning, and knockout engineering. (avma.org)

The investigators hoped that the cumulus cells DNA would launch the process of early embryonic development that leads to a hollow sphere called a blastocyst, which would contain stem cells. (scientificamerican.com)
12. Establishment and in vitro differentiation of a new embryonic stem cell line from human blastocyst. (nih.gov)
First, he identified the three-day-old blastocyst (the tiny embryo from which stem cells are extracted) as the point of ethical controversy. (christianitytoday.com)
When an embryo actually starts to develop, when it starts to have some characteristics of a human like brain structures for instance and I admit I'm biased because I'm a neuroscientist that has much more value than a blastocyst," he explains. (christianitytoday.com)
In human embryonic stem cell research (hESCR), the beauty of the human blastocyst is destroyed for the sake of using these hESC to treat other diseases. (prolifelouisiana.org)
The stem cells of the human blastocyst are removed, leaving the blastocyst dead and unable to continue its maturation process. (prolifelouisiana.org)
At the blasotcyst stage, they strip the stem cells from the human, leaving the blastocyst dead. (prolifelouisiana.org)
From there, Dr. Brinster became interested in modifying the development of animals and their germ lines, and he went on to become the first person to show that it was possible to colonize a mouse blastocyst with stem cells from older embryos. (avma.org)
Respondents also disagreed with the definition of human embryonic stem cells in the draft Guidelines, and asked that the NIH define them as originating from the inner cell mass of the blastocyst. (nih.gov)
The NIH modified the definition to say that human embryonic stem cells "are cells that are derived from the inner cell mass of blastocyst stage human embryos, are capable of dividing without differentiating for a prolonged period in culture, and are known to develop into cells and tissues of the three primary germ layers. (nih.gov)

The earlier Chinese publications, although limited in scope, found CRISPR caused editing errors and that the desired DNA changes were taken up not by all the cells of an embryo, only some. (technologyreview.com)
Embryos at this stage are tiny clumps of cells invisible to the naked eye. (technologyreview.com)
Concerns about ethics, errors (accidental or intentional) and possible fraud have dogged the stem-cell researcher Woo Suk Hwang, from Seoul National University in South Korea, since his landmark 2004 Science paper on stem cells from a cloned human embryo. (bioedonline.org)
First, ACT didnt produce any stem cells. (scientificamerican.com)
Among the eight eggs injected with cumulus cells, two divided until they became four-cell embryos, and one proceeded until it reached six cells. (scientificamerican.com)
Adult Stem Cells Rebuild Alabama Woman's Heart / 'Your Own Stem Cells Work! (physiciansforlife.org)
Researchers want to create hybrid embryos by merging human cells with animal eggs, in the hope they will be able to extract valuable embryonic stem cells from them. (physiciansforlife.org)
Opponents of the research and some religious groups say the work blurs the distinction between humans and animals, and creates embryos that are destined to be destroyed when stem cells are extracted from them. (physiciansforlife.org)
Human embryonic stem cells: research, ethics and policy. (nih.gov)
Researchers have achieved a major milestone in embryonic stem cell research: they isolated embryonic stem cells for the first time from a cloned primate embryo. (nih.gov)
Since embryonic stem cells have the ability to form virtually any cell type in the body, those taken from a cloned embryo could potentially be used to treat many diseases. (nih.gov)
Before this new study was published, Nature asked another group of researchers to confirm that the stem cells were genetically identical to the donor skin cells. (nih.gov)
The mechanisms underlying the low efficiency of reprogramming somatic cells into induced pluripotent stem (iPS) cells are poorly understood," write the authors. (lifesitenews.com)
This latest discovery related to induced pluripotent stem cells could prove a set-back in the efforts to use them in regenerative medicine. (lifesitenews.com)
1. Establishment of a human embryonic germ cell line and comparison with mouse and human embryonic stem cells. (nih.gov)
2. Human embryonic germ cells isolation from early stages of post-implantation embryos. (nih.gov)
3. Fibroblast-like cells derived from the gonadal ridges and dorsal mesenteries of human embryos as feeder cells for the culture of human embryonic germ cells. (nih.gov)
7. Generation and characterization of pluripotent stem cells from cloned bovine embryos. (nih.gov)
17. Characterization and multilineage differentiation of embryonic stem cells derived from a buffalo parthenogenetic embryo. (nih.gov)
20. High density cultures of embryonic stem cells. (nih.gov)
Embryos and germ cells are commonly stored at ultra-low temperatures in liquid nitrogen. (genengnews.com)
Although the researchers could not retrieve healthy and functional sperm cells following the freeze-drying process, they could retrieve sperm DNA which they injected into oocytes to clone mice offspring. (genengnews.com)
Since Wakayama reported cloning whole animals from freeze dried sperms DNA, frog 3 and sheep 4 have been successfully cloned from somatic cells, indicating that the storage of gametes is not essential as a genetic resource. (genengnews.com)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. (genscript.com)
The current collections at the MMRRC Consortium consists of 61,866 unique mutant al eles (submission include live mice, frozen germplasm, or embryonic stem cells). (nih.gov)
The House of Lords approved a law allowing embryos to be created for the harvesting of stem cells. (equip.org)
Because fetal tissue research - especially research on embryonic stem cells - is being trumpeted as a great scientific breakthrough and a biomedical revolution. (equip.org)
Dr. Hwang Woo Suk and his colleagues, the only researchers in the world to convince the scientific community that they had cloned human embryos and derived embryonic stem cells (ESCs) from them, are now seen as having perpetrated a massive deception. (thenewatlantis.com)
As the New York Times has observed, "The technique for cloning human cells, which seemed to have been achieved since March 2004, now turns out not to exist at all, forcing cloning researchers back to square one. (thenewatlantis.com)
This is at least the third time in eight years that we have heard announcements of success in cloning human embryos for their stem cells, only to find that the claim has little basis in fact. (thenewatlantis.com)
Although ACT's researchers only managed to bring one cloned embryo to the six-cell stage - and whether they created an embryo at all remains uncertain - they were certainly not able to obtain any stem cells. (thenewatlantis.com)
and secondly, "embryonic" stem cells, which are obtained by the disaggregation of human embryos. (lifeissues.net)
The Holy See opposes the cloning of human embryos for the purpose of destroying them in order to harvest their stem cells, even for a noble purpose, because it is inconsistent with the ground and motive of human biomedical research, that is, respect for the dignity of human beings. (lifeissues.net)
However, the Holy See applauds and encourages research using adult stem cells, because it is completely compatible with respect for the dignity of human beings. (lifeissues.net)
The unexpected plasticity of adult stem cells has made it possible to use this type of undifferentiated, self-renewing cell successfully for the healing of various human tissues and organs, 1 particularly in hearts damaged after myocardial infarction. (lifeissues.net)
Above all, it is universally agreed that the use of adult stem cells does not entail any ethical problems. (lifeissues.net)
3. By contrast, research using human embryonic stem cells has been hampered by important technical difficulties. (lifeissues.net)
5 Moreover, embryonic stem cells have caused tumors in animal models 6 and might seed cancer if administered to human patients. (lifeissues.net)
8 Technical problems aside, the need to extract these cells from living human embryos raises ethical questions of the highest order. (lifeissues.net)
However, the use of cloned embryonic stem cells entails a high risk of introducing cells from abnormal embryos into patients. (lifeissues.net)
9 Embryonic stem cells harvested from abnormal and unfit embryos will carry their "epigenetic defects" and transmit at least part of them to their daughter cells. (lifeissues.net)
The transfer of such cloned embryonic stem cells into a patient would be therefore extremely hazardous: these cells might provoke genetic disorders, or initiate leukemias or other cancers. (lifeissues.net)
Keirstead catapulted out of obscurity when he and a colleague made paralyzed rats walk by injecting them with cells derived from human embryonic stem cells. (christianitytoday.com)
And I think that if you talk to any scientist for or against stem cells, they're going to tell you that's the case. (christianitytoday.com)
If adopted in their current form, the guidelines would allow federal funds to be used for research on human embryonic stem (ES) cells isolated from "spare" embryos from fertility clinics. (newscientist.com)
But some researchers are disappointed that the NIH has not gone further and opened the door to the future funding of projects involving cells taken from embryos created specifically for research - including those made by cloning. (newscientist.com)
As well as restricting funding to research on cells derived from spare fertility-clinic embryos, the draft NIH guidelines include standards to ensure that embryo donors consented to the cells' use in research and that they received no payments or other inducements. (newscientist.com)
The guidelines would also prohibit federal funding for research in which human ES cells - or reprogrammed human "induced pluripotent" stem cells, which have similar properties - are introduced into pre-implantation primate embryos, or any breeding experiment in which an animal might produce sperm or eggs derived from these human cells. (newscientist.com)
NIH is looking forward to expanding research involving human embryonic stem cells," acting NIH director Raynard Kington said in a 17 April teleconference, although he could not put an approximate figure on the number of eligible lines when pressed by New Scientist . (newscientist.com)
Still, several teams are now trying to isolate stem cells from human embryos created by cloning - a feat once fraudulently claimed to have been achieved by South Korea's Woo Suk Hwang. (newscientist.com)
If these groups succeed, there will be a strong demand from stem cell biologists to study these cells using federal funding - which would not be allowed under the draft guidelines. (newscientist.com)
The embryonic stem cells extracted from a cloned embryo can become any other type of human cell. (capitalismmagazine.com)
The Australian government has issued its first license for cloning human embryos to obtain embryonic stem cells. (bioedge.org)
2 Such embryonic destruction is usually carried out as a means of obtaining the embryo's 'stem cells'--cells which some believe have the potential to revolutionize medicine by restoring the health of persons suffering from a variety of debilitating conditions. (cbhd.org)
In 2001 researchers in Massachusetts announced that they were trying to clone humans in an attempt to extract stem cells . (infoplease.com)
The cloning of two monkeys that was reported in 2017 by researchers at the Chinese Academy of Science, Shanghai, did not use DNA from adult cells but from an aborted macaque fetus. (infoplease.com)
In its simplest form, cloning is defined as the exact replication of cells. (who.int)
We also know that within humans (and other animal species) there are cells called stem cells. (who.int)
The stem cells possess pluripotential characteristics, and can differentiate into various cells and tissues when nurtured and grown in different culture media. (who.int)
Embryonic stem cells, on their face value, are truly beautiful and amazing part of human development since they are the foundational cells for every cell in the human body! (prolifelouisiana.org)
And because of the pluripotency of embryonic stem cells and the corresponding supposed hope for medicinal use, researchs have sought to isolate these hESC. (prolifelouisiana.org)
However, because theses stem cells are a necessary part of the embryos development, isolating the hESC necesitates the destruction of the embryo, which turns what was beautiful into a disgrace. (prolifelouisiana.org)
These cells are then placed in a pietri dish and are encouraged to multiply undifferentiated until a "stem cell line" is created. (prolifelouisiana.org)
Because in the embryo these cells differentiate into all different types of cells at amazing speed, it is very difficult to control the type and rate of differentiation. (prolifelouisiana.org)
Again, the hESC gathered from the In Vitro embryo are not going to be used to heal that embryo, meaning wherever these hESC are used, there will be the concern that the immune sysem of the patient will reject the stem cells. (prolifelouisiana.org)
Valuable as these investigations have been, they have not been able to place differentiation into the larger context of development, specifically into the context of the earlier developmental process of cell determination, when embryonic stem cell lineages are formed and the genetic regulatory programs for cell type-specific gene activation and expression are acquired by stem cells. (nih.gov)
These determined proliferative stem cells are stable in culture and retain their ability to differentiate in mitogen-depleted medium. (nih.gov)
Human pluripotent stem cells (hPSCs) are inherently sensitive cells. (nih.gov)
This inefficiency of cell cloning represents a major obstacle for the standardization and streamlining of gene editing in induced pluripotent stem cells for basic and translational research. (nih.gov)
These are the stem cells that we re talking about. (issues2000.org)
ZEESE: I agree with the need for adult stem-cell research because I think science may find that mature cells are better than embryonic. (issues2000.org)
Q: What about expanding federal funding for research using embryonic stem cells? (issues2000.org)
Lanza also worked on cloning human embryos to harvest stem cells, which could be used to treat dieases. (asu.edu)
Act (42 U.S.C. 289g(b)). (b) For purposes of this section, the term `human embryo or embryos' includes any organism not protected as a human subject unde r 45 CFR Part 46 as of the date of the enactment of this Act, that is derived by fertilization, parthenogenesis, cloning, or any other means from one or more human gametes or human diploid cells. (nih.gov)
The term "human embryo or embryos" includes any organism not protected as a human subject under 45 CFR 46, as of the date of enactment of the governing appropriations act, that is derived by fertilization, parthenogenesis, cloning, or any other means from one or more human gametes or human diploid cells. (nih.gov)
Research creating or using human stem cells that may have the ability to develop into all embryonic and extra-embryonic cell types. (nih.gov)
Removing Barriers to Responsible Scientific Research Involving Human Stem Cells. (nih.gov)
The NIH notes that although the Guidelines pertain primarily to the donation of embryos for the derivation of hESCs, one Section also applies to certain uses of both hESCs and human induced pluripotent stem cells. (nih.gov)
Also, the Guidelines discuss applicable regulatory standards when research involving human adult stem cells or induced pluripotent stem cells constitutes human subject research. (nih.gov)
Respondents expressed concern that derivers of stem cells might profit from the development of hESCs. (nih.gov)
Others noted that because the stem cells eligible for use in research using NIH funding under the draft Guidelines are those cells that are subject to existing patents, there will be insufficient competition in the licensing of such rights. (nih.gov)
http://www.ott.nih.gov/policy/policies_and_guidelines.aspx Even where such policies are not directly applicable, the NIH encourages others to refrain from imposing on the transfer of research tools, such as stem cells, any conditions that hinder further biomedical research. (nih.gov)
The study was performed in several Good Manufacturing Practice laboratories manufacturing diverse cell therapy products (human mesenchymal stromal cells, hematopoietic progenitor cells, leukapheresis products, fibroblasts and induced pluripotent stem cells). (bvsalud.org)

Harry Griffin, assistant director at the Roslin Institute, which cloned Dolly the sheep, also questioned whether the work should have been published. (scientificamerican.com)
Professor Ian Wilmut, whose team cloned Dolly the sheep, is waiting for the HFEA's decision before applying to create hybrid embryos to study motor neurone disease with Professor Chris Shaw at the Institute of Psychiatry in London. (physiciansforlife.org)
The last edition of Bio-Tech had to be hastily rewritten to include information about Dolly the sheep, who was cloned from another sheep as the manuscript was being finalized. (sjgames.com)
In 1997 Dolly the Sheep was the first mammal ever to be cloned. (cbhd.org)
That is how the first cloned sheep, named "Dolly", was created [3]. (who.int)

Why the apparent haste to clone humans? (bmj.com)
Although none of the embryos were allowed to develop for more than a few days-and there was never any intention of implanting them into a womb-the experiments are a milestone on what may prove to be an inevitable journey toward the birth of the first genetically modified humans. (technologyreview.com)
In May, the government withdrew its opposition in a draft fertility bill and now seeks to outlaw only embryos created by mixing sperm and eggs from humans and animals. (physiciansforlife.org)
Similar contractions in the early human embryo may contribute to the frequent mosaicism for different repeat lengths that are seen in humans with FXS. (nih.gov)

WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
See G. Kolata, Clone (1997). (infoplease.com)
By Presidential memorandum of March 4, 1997, NIH is prohibited from using Federal funds for cloning of human beings. (nih.gov)

Our proof-of-concept experiments show that replacement of the entire cytoplasm of oocytes from a sensitive mouse strain overcomes massive embryo developmental arrest characteristic of non-manipulated oocytes. (elifesciences.org)
The cleavage (12.0 to 19.5%), 4-cell (8.0 to 12.0%) and 8-cell (4.0 to 8.0%) formation rates in sei whales did not vary significantly between embryos derived from either grade A or B oocytes and between embryos cultured in either fetal whale serum (FWS)- or bovine serum albumin (BSA)-supplemented medium. (cambridge.org)
The cleavage (4.0 to 14.8%), 4-cell (0.0 to 7.5%) and 8-cell (0.0 to 2.6%) formation rates in Bryde's whales did not vary significantly between embryos derived from either grade A or B oocytes and between embryos cultured in either FWS- or BSA-supplemented medium. (cambridge.org)

The technique used to test for genetic disorders is embryo screening. (educationquizzes.com)
As species continue to face massive extinction, preserving genetic material through judicious biobanking to enable cloning is key to promoting the survival of species and maintaining biodiversity. (genengnews.com)
Therefore, it is crucial to develop methods where genetic material can be preserved long-term with minimal resources that enable the cloning of viable and fertile offspring upon prolonged storage. (genengnews.com)
In addition, each Center provides services on a fee-for-service basis to investigators which includes specialties such as colony management and breeding services, assisted reproduction services, embryonic stem cell and microinjection services, genetic analysis, phenotyping, pathology and diagnostics. (nih.gov)
A clone is an organism that is a genetic copy of an existing one. (who.int)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
Human cloning is the creation of a human being whose genetic make-up is nearly identical 1 to that of a currently or previously existing individual. (cbhd.org)
The clonal mouse embryo cell line, C3H/10T1/2, clone 8 (10T1/2) provides a unique opportunity to examine the molecular genetic regulation of both the developmental determination of vertebrate stem cell lineages and their subsequent differentiation. (nih.gov)

These structures are preventing acquisition to and dissemination of the accurate scientific information regarding the full humanity and personhood of the early human embryo. (lifeissues.net)

In a true mammalian clone (as in Gurdon's frog clone) the nucleus from a body cell of an animal is inserted into an egg, which then develops into an individual that is genetically identical to the original animal. (infoplease.com)
For his doctoral thesis, Dr. Brinster developed the first reliable in vitro culture system for early mammalian embryos. (avma.org)

One of the most urgent yet least discussed medical dilemmas today is access to the correct basic scientific information regarding the human embryo - scientific information which demonstrates empirically that normally every human being begins to exist at fertilization in the woman's fallopian tube as a single-cell embryo, the zygote. (lifeissues.net)
2 Indeed, fertilization is the beginning of the existence of the human being, the human embryo, the human organism, the human individual, and the "embryonic period. (lifeissues.net)

The director of the lobby group Australians for Ethical Stem Cell Research, David van Gend, criticised the issuing of the licence. (bioedge.org)
However, that is not the same for ethical stem cell research. (prolifelouisiana.org)

Now Mitalipov is believed to have broken new ground both in the number of embryos experimented upon and by demonstrating that it is possible to safely and efficiently correct defective genes that cause inherited diseases. (technologyreview.com)

cloning succeeds 4% or less of the time in the species that have been successfully cloned. (infoplease.com)
Some children have been successfully treated with blood stem cell, or bone marrow, transplants. (nih.gov)
NIH researchers successfully treated adults with severe sickle cell disease using a modified stem cell transplant approach that doesn't require extensive immune-suppressing drugs. (nih.gov)

The answer is that stem cell research requires the destruction of living human beings. (equip.org)
Furthermore, government-sanctioned destruction of human embryos isn't just unethical, it violates existing law. (equip.org)
Surprised by this declaration, I asked if he anticipated the destruction of any other embryos in his work. (christianitytoday.com)
Then he added, "This idea of the destruction of multiple embryos being a problem is complete nonsense. (christianitytoday.com)
This latter type of cloning involves the creation and subsequent destruction of a clonal human embryo for the purposes of scientific or medical research. (cbhd.org)
.'5 Although abortion is currently legal in this country, the majority of U.S. citizens would surely react strongly against and refuse to adhere to a governmental policy that mandated the destruction of human life (or the punishment/ incarceration of women known to have defied the law by giving birth to human clones). (cbhd.org)

Except for changes in the hereditary material that come about by mutation , all members of a clone are genetically identical. (infoplease.com)

The effects of COCs grades and protein supplementation in embryo culture medium on development of in vitro fertilized (IVF) embryos were evaluated in sei and Bryde's whales in Experiment 2. (cambridge.org)

Cloning entails taking the nucleus - the compartment that contains the DNA - from an adult cell and putting it into an egg from which the original nucleus has been removed. (nih.gov)

They did not present in their paper any evidence that the nuclei that they transferred into the eggs were biologically active," notes Brigid Hogan, a developmental biologist at Vanderbilt University and a member of a National Academy of Sciences panel examining the scientific and medical aspects of human cloning. (scientificamerican.com)
There is, in our view, no way that individual embryos can be created to provide individual treatment for this number of peopleit would be incredibly costly, and there are simply not enough human eggs available. (scientificamerican.com)
Collecting functional sperms, particularly from infertile males, as well as collecting female eggs from ovaries or fertilized embryos pose significant challenges for biobanking. (genengnews.com)
Using this method of embryo manipulation, he next worked out many aspects of the metabolism and development of eggs and early embryos. (avma.org)

Is a consensus possible on stem cell research? (bmj.com)
Stem cell research involving cloned embryos? (medscape.com)
and (3) on the incorrect science propagated historically and currently in international bioethics debates on human cloning, human embryonic, and human fetal stem cell research. (lifeissues.net)
A chronology of Woo Suk Hwang's stem-cell research. (bioedonline.org)
Not only babies who would grow into adult clones, but also cloning of embryos for stem cell research. (sjgames.com)
We support stem cell research that does not destroy or clone human embryos. (cacatholic.org)
Embryonic Stem Cell Research: Humane for Whom? (equip.org)
First, do no harm" has been the solemn oath of generations of physicians, but advocates of stem cell research would have us believe it's not a problem. (equip.org)
It's the possibility that the therapies derived from stem cell research could potentially alleviate the suffering of millions. (equip.org)
Urge them to stay the course and make sure federally funded stem cell research remains illegal - regardless of what Hollywood superstars may say. (equip.org)
General information about, and a Christian perspective on, stem cell research, may be accessed at www.stemcellresearch.org. (equip.org)
PUSHING THE ENVELOPE: (Clockwise from top left) A 2005 South Korean stem-cell research stamp commemorated what was hailed as a remarkable scientific achievement and what is now remembered as an infamous case of scientific fraud. (the-scientist.com)
Recent developments in animal cloning coupled with advances in human embryonic stem cell research have heightened the need for legislation on this issue. (cbhd.org)
The triumphalistic rhetoric with which President Obama recently announced his administration's commitment to embryonic stem-cell research"and the hosannas with which it was greeted by the likes of the New York Times "heralded something more than just an adjustment in policy by a newly empowered political party. (firstthings.com)
By David Prentice U.S. District Judge Royce Lamberth has dismissed a federal lawsuit challenging current NIH guidelines that allow taxpayer funding of human embryonic stem cell research. (nationalrighttolifenews.org)
I support the expansion of embryonic stem cell research, I voted to override the president s veto, a bill that was bipartisan, worked out so that we could advance embryonic stem cell research. (issues2000.org)
So there s a major difference between the two of us on embryonic stem cell research. (issues2000.org)
Q: Should we pursue embryonic stem-cell research? (issues2000.org)
STEELE: I am four-square for stem-cell research, and accelerating the funding, with respect to cord blood and adult stem cell research. (issues2000.org)
I cosponsored legislation to promote stem cell research, and I applauded President Obama's March 2009 Executive Order overturning the Bush Administration's longstanding policy and allowing the responsible use of federal funds for embryonic stem cell research. (issues2000.org)
But the plurality of the title refers to the wider subject of modern genetics and the great leaps that have recently been made in science that have thrown up amazing possibilities, some of which are explored in the play (IVF allowing gay couples to have their own children, stem cell research on embryos, cloning). (britishtheatreguide.info)
The real conflict comes between Jerry (previously a scientist, now a science journalist) and Jude, over the thorny issue of stem-cell research. (britishtheatreguide.info)
The intricacies of stem cell research are certainly challenging for a playwright but Badham's parallel stories are a good way of expanding the issues without the audience feeling an agenda is being shoved down its collective throat. (britishtheatreguide.info)
The National Institutes of Health (NIH) is hereby publishing final "National Institutes of Health Guidelines for Human Stem Cell Research" (Guidelines). (nih.gov)
The Executive Order states that the Secretary of Health and Human Services, through the Director of NIH, may support and conduct responsible, scientifically worthy human stem cell research, including human embryonic stem cell (hESC) research, to the extent permitted by law. (nih.gov)
These Guidelines implement Executive Order 13505, as it pertains to extramural NIH-funded stem cell research, establish policy and procedures under which the NIH will fund such research, and helps ensure that NIH-funded research in this area is ethically responsible, scientifically worthy, and conducted in accordance with applicable law. (nih.gov)
Internal NIH policies and procedures, consistent with Executive Order 13505 and these Guidelines, will govern the conduct of intramural NIH stem cell research. (nih.gov)
Respondents felt the title of the NIH draft guidelines was misleading, in that it is entitled "National Institutes of Health Guidelines for Human Stem Cell Research," yet addresses only one type of human stem cell. (nih.gov)
The Guidelines do not address the distribution of stem cell research material. (nih.gov)
It is, however, the NIH's expectation that stem cell research materials developed with NIH funds, as well as associated intellectual property and data, will be distributed in accordance with the NIH's existing policies and guidance, including "Sharing Biomedical Research Resources, Principles and Guidelines for Recipients of NIH Grants and Contracts" and "Best Practices for the Licensing of Genomic Inventions. (nih.gov)

Cloning is also known as "somatic cell nuclear transfer" (SCNT), the technical process by which cloning is performed. (cbhd.org)

Researchers have demonstrated they can efficiently improve the DNA of human embryos. (technologyreview.com)
The first known attempt at creating genetically modified human embryos in the United States has been carried out by a team of researchers in Portland, Oregon, MIT Technology Review has learned. (technologyreview.com)
Some cloning advocates claim that this event has no implications beyond the malfeasance of a few Korean researchers. (thenewatlantis.com)
What does it mean when even embryonic stem-cell researchers have some qualms about their work? (christianitytoday.com)

This means that when hESC are removed from the embryo, the source that directs and provides a blueprint for differentiation, hESC are unstable and unreliable. (prolifelouisiana.org)
The stability of the repeat was examined in patient-derived iPSCs and in neural progenitors and neurons derived from these iPSCs and in individual clones isolated from a FXS hESC line. (nih.gov)

On November 25, 2001, a Massachusetts biotechnology company, Advanced Cell Technology (ACT), reported in an online journal e-biomed: The Journal of Regenerative Medicine that it had cloned the first human embryos. (scientificamerican.com)
By Dave Andrusko For years, bioethicist Wesley J. Smith has kept close tabs on the California Institute of Regenerative Medicine, established after voters in 2004 approved a state ballot initiative, Proposition 71, which funded embryonic stem cell/human cloning research using $3 billion in bonds. (nationalrighttolifenews.org)

Although we are here this week to discuss and examine the more obvious causes of the pressures and discriminations against ObGyn's to practice medicine according to their consciences, my purpose is rather with identifying the "larger picture", i.e., the more subtle but pervasive pressures and discriminations that stem from the structures and politics informed by international bioethics. (lifeissues.net)
Human cloning] would be taking a major step into making man himself simply another one of the man-made things," says Leon Kass, chairman of the President's Council on Bioethics. (capitalismmagazine.com)

The developmental potential of early embryos is mainly dictated by the quality of the oocyte. (elifesciences.org)
13. Cluster characterization of mouse embryonic stem cell-derived pluripotent embryoid bodies in four distinct developmental stages. (nih.gov)
General policy information may be found on the NIH Office of Science Policy (OSP) - Stem Cell and Developmental Biology Policy page . (nih.gov)

Columnist Armstrong Williams condemns all cloning as "human egotism, or the desire to exert our will over every aspect of our surroundings," and cautions: "We're not God. (capitalismmagazine.com)

I was asked this question by Hans S. Keirstead, an embryonic stem-cell researcher at the Reeve-Irvine Research Center in Southern California. (christianitytoday.com)

Asked what the difference is between an iPS cell that has been reverted back to its pluripotent state and an embryo in its earliest, single-cell stage, Gurdon replied, "Probably none. (lifesitenews.com)

Later experiments in cloning resulted in the development of a sheep from a cell of an adult ewe (in Scotland, in 1996), and since then rodents, cattle, swine, and other animals have also been cloned from adult animals. (infoplease.com)

Supporters of ESCR think it isn't wrong to destroy embryos for use in research. (nationalrighttolifenews.org)

By Wesley J. Smith The embryonic stem cell and human cloning research debates are not "science" arguments, but rather, disputes over proper ethics in the pursuit of science. (nationalrighttolifenews.org)

16. Cell surface 5T4 antigen is transiently upregulated during early human embryonic stem cell differentiation: effect of 5T4 phenotype on neural lineage formation. (nih.gov)
Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo. (genscript.com)

In the current study, Wakayama's team generate healthy cloned mice offspring from freeze dried somatic cell nuclei through an adapted nuclear transfer procedure. (genengnews.com)
It has been well established that most of the non-human embryos produced through nuclear transfer cloning are abnormal, with a deficiency in several of the genes (imprinted and non imprinted) necessary to the development of the early embryo. (lifeissues.net)
Cloning in higher species involves somatic cell nuclear transfer, a process in which the nucleus of a somatic (non-germ) cell is taken out and inserted into an enucleated fertilized female germ cell (egg, ovum). (who.int)

According to some biologists, a cloned embryo would attain its true status as an embryo only when the DNA from the cumulus cell transferred into the egg began transcription (in which its genes begin to issue instructions to make proteins for embryonic development). (scientificamerican.com)
The egg then "reprograms" the adult nucleus so that the cell behaves like an embryo but has the genes of the adult cell. (nih.gov)

From a biological standpoint, bringing cloned human embryos to birth would be dangerous for the human species. (lifeissues.net)
Lanza's team cloned the endangered species of gaur Bos gaurus. (asu.edu)

In addition, the investigators selected nine female and three male cloned mice and allowed them to mate. (genengnews.com)
To accomplish these goals, the MMRRC Consortium is responsible for obtaining mice from donating investigators and establishing banks of cryopreserved sperm, embryos, and related materials for distribution to research investigators. (nih.gov)

T he details of the cloning scandal in South Korea are by now familiar. (thenewatlantis.com)

In 2007, he unveiled the world's first cloned monkeys. (technologyreview.com)

Anatomy57

Organisms24

Diseases4

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment56

Phenomena and Processes69

Disciplines and Occupations6

Technology, Industry, Agriculture1

Information Science5

Health Care1

Created human embryos1

Reproductive29

Therapeutic26

Embryonic stem-cell10

Scientists23

Cryopreservation of mouse embryos1

Donated sperm1

Vitro fertilization4

Blastocyst10

Cells83

Dolly5

Humans4

19973

Oocytes3

Genetic8

Early human embryo1

Mammalian2

Fertilization2

Ethical2

Inherited diseases1

Successfully3

Destruction6

Genetically identical1

Experiment1

Entails1

Eggs4

Cell research30

SCNT1

Researchers4

HESC2

Regenerative Medicine2

Bioethics2

Developmental3

Condemns1

Researcher1

Pluripotent1

Sheep1

Destroy1

Ethics1

Differentiation2

Nuclear3

Genes2

Species2

Mice2

South Korea1

Monkeys1