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  • embryonic
  • Since little is known about signally mechanisms regulating self-renewal and differentiation of UCBSCs, we sought insight from embryonic stem cell (ESC) literature to guide our studies. (tdl.org)
  • neural
  • Thus, after exposure to different agents, these cells are able to express antigens of diverse cellular lineages, including the neural type [ 26 - 31 ]. (hindawi.com)
  • We have discussed the possible attempts to make use of UCB therapies to generate neural cells and tissues with developmental and functional similarities to neuronal cells. (omicsonline.org)
  • In addition, more of BrdU-positive cells expressed neural stem/progenitor cell nestin and oligo-lineage cell such as NG2, CNPase, MBP and glial fibrillary acidic protein typical of astrocytes in the MSC-transplanted rats. (hindawi.com)
  • A new study of mitochondrial deficits in iPSC-derived neural cells, funded by the National Institutes of Health and published in Science Translational Medicine, shows that patient-derived stem cells yield differing responses for cells derived from patients with different etiologies of Parkinson's disease. (stemcellumbilicalcordblood.com)
  • HSCT
  • A second HSCT was planned with cord blood as the graft source, because disease progression implied a need for an urgent care. (hindawi.com)
  • A third HSCT using cord blood as the graft source was planned in non-CR status after treatment with a hypomethylating agent, azacitidine, [ 1 , 2 ] at the age of 53 again, because the patient had no significant comorbidities. (hindawi.com)
  • differentiate
  • These cells are defined by their ability to self-renew as well as to differentiate into committed progenitors of the different myeloid and lymphoid compartments generating all of the blood cell lineages (1). (scielo.br)
  • Induced pluripotent stem cells are the third category, where somatic cells are induced to convert into pluripotent stem cells under certain condition and differentiate into a specific cell types [ 2 , 3 ]. (omicsonline.org)
  • clinical
  • For the clinical trial, 34 patients were randomly assigned to receive a low dose or high dose of the cells subcutaneously. (medicalnewstoday.com)
  • Replication of this enormous cell amplification with hematopoietic growth factors in vitro would allow the generation of large numbers of cells that could be used for a variety of clinical applications (7). (scielo.br)