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  • efficacy
  • Thus, means to enhance numbers and/or potency of collected cells and their engrafting capability through ex-vivo and/or in-vivo maneuvers would likely enhance the efficacy and applicability of CB transplantation. (stembook.org)
  • Dr. Wanzhang Yang, who led the study at Nanshan Affiliated Hospital of Guangdong Medical College commented, 'This important study, which is the largest of its kind, demonstrates the safety and efficacy of using cord-blood-derived stem cells to treat a variety of neurological conditions. (news-medical.net)
  • Recent studies have reported the efficacy of stem cell therapy in nephropathy animal models. (lww.com)
  • colitis syndrome
  • This week's issue of the New England Journal of Medicine evaluates cord colitis syndrome in cord-blood stem-cell transplantation. (gastrohep.com)
  • The condition, termed cord colitis syndrome, developed in 11 of 104 patients, according to a retrospective study done by Alex F. Herrera, MD, of Brigham and Women's Hospital in Boston, and colleagues. (medpagetoday.com)
  • The risks of prolonged antibiotic therapy, including promotion of antimicrobial resistance, must be weighed against the benefits of treating the cord colitis syndrome effectively," they stated. (medpagetoday.com)
  • In comparing the histologic findings associated with the cord colitis syndrome with findings in GVHD, the authors noted that in GVHD there is no granuloma formation, epithelial infiltration, or metaplasia of Paneth cells as was seen in the new syndrome. (medpagetoday.com)
  • They also noted that the histopathologic pattern seen in the cord colitis syndrome resembles that of Crohn's disease, and that antibiotics have been found to be helpful in that autoimmune disease. (medpagetoday.com)
  • A greater understanding of the cord colitis syndrome may provide insights into the pathophysiology of Crohn's disease," Herrera and colleagues observed. (medpagetoday.com)
  • biological
  • Caution is clearly required for non HSC/HPC stem/progenitor cell uses of CB, based on insufficient biological and preclinical information for MSC, EPC, and iPSC. (stembook.org)
  • Leukemia
  • Patients with cerebrospinal fluid positive for leukemia receive Ara-C IT every 2-3 days until a repeat LP shows no remaining leukemic cells. (clinicaltrials.gov)
  • Cryopreservation
  • The second flawed assumption is that the stem cells in the UCB unit will exhibit the same quality and potency when they are thawed and prepared for a patient, as they did when the unit was collected and tested prior to cryopreservation. (parentsguidecordblood.org)
  • HemoGenix assays can measure stem cell quality before cryopreservation ( STEMpredict ) and potency after thawing ( HALO-96 PQR ) . (parentsguidecordblood.org)
  • If the unit contains red cells at time of cryopreservation, the cryopreserved dose must be at least 2.0 x 107 TNC/kg. (clinicaltrials.gov)
  • adults
  • Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole. (springer.com)
  • clinical
  • This information could provide the means to modulate these cells for greater clinical advantage. (stembook.org)
  • There is also the potential, as yet far from proven in a clinical sense for use of mature cells generated from HSC/HPC, and for non-HSC/HPC uses of CB. (stembook.org)
  • The editors and authors of this book not only address current clinical science and banking of umbilical-cord blood, but also advance new concepts in medical therapeutics that use umbilical-cord blood. (waterstones.com)
  • treatment
  • Dr. Travis Ye, Beike Biotech's CEO, commented, 'This groundbreaking research is consistent with the safety record we have compiled after providing stem cells for the treatment of more than 8,000 patients. (news-medical.net)
  • A unit of 5/6 HLA-matched cord blood was transplanted after treatment with a preparation regimen comprising busulfan (12.8 mg/kg, i.v.) and cyclophosphamide (120 mg/kg) at 16 months from the first transplantation. (hindawi.com)
  • 2 Allogeneic Stem Cell Transplantation in AML Over the past 3 decades allogeneic transplantation has been established as an effective salvage treatment for relapsed and high risk AML. (docplayer.net)
  • Animals that were found to be nephropathic were divided into two groups: group II (animals were not subjected to treatment) and group III (animals were treated with an intravenous injection of stem cells). (lww.com)
  • http://www.lls.org/ resourcecenter/freeeducationmaterials/treatment/cordblood Accessed April 1, 2014. (lifebankusa.com)