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  • treatment
  • The main focuses of research, diagnosis and treatment are on leukemia and lymphomas, malignancies of the gastrointestinal tract, tumors of germ cells (e.g. testicles) and malignancies of bone and connective tissues. (bookinghealth.com)
  • lymphoma
  • In diseases like leukemia and lymphoma, a cell in the bone marrow becomes cancerous. (christian-history.org)
  • Patients suffering from a variety of diseases, such as leukemia, lymphoma, myeloma, myelodysplastic syndromes, aplastic anemia and some immune disorders are the conditions for which a transplant is most frequently used. (cornellbmt.org)
  • Resimmune or A-dmDT390-bisFv(UCHT1) is an experimental drug - an anti-T cell immunotoxin - that is being investigated for treatment of T cell blood cancers such as cutaneous T cell lymphoma (CTCL). (wikipedia.org)
  • Since 2009, Resimmune is being tested against cutaneous T cell lymphoma, and is in a Phase II trial: A-dmDT390-bisFv(UCHT1) Immunotoxin Therapy for Patients With T-cell Diseases. (wikipedia.org)
  • Immunodeficiency-associated Burkitt lymphoma is usually associated with HIV infection or occurs in the setting of post-transplant patients who are taking immunosuppressive drugs. (wikipedia.org)
  • Since Burkitt lymphoma and other B-cell lymphomas are a clonal proliferative process, all tumor cells from one patient are supposed to possess identical IgH genes. (wikipedia.org)
  • The tumor cells in Burkitt lymphoma generally strongly express markers of B cell differentiation (CD20, CD22, CD19), as well as CD10 and BCL6. (wikipedia.org)
  • The high mitotic activity of Burkitt lymphoma is confirmed by nearly 100% of the cells staining positive for Ki67. (wikipedia.org)
  • multiple myeloma
  • Studies show that multiple myeloma patients who undergo both chemo and a stem cell transplant survive longer and without symptoms. (ivanhoe.com)
  • If someone has a single plasma cell tumor then the disease is called a solitary plasmacytoma but if they have more than one plasma cell tumor then it's called multiple myeloma. (ivanhoe.com)
  • There are different things that characterize multiple myeloma which include: low blood counts, bone and calcium problems, kidney problems, infections, and monoclonal gammopathy, which is when a person has many copies of the same antibody. (ivanhoe.com)
  • Donation
  • Only about 1 in 500 people who sign up for marrow donation have to give, but every person added increases the chance of finding a donor. (christian-history.org)
  • During this visit you will discuss the donation process with a physician and a transplant coordinator. (cornellbmt.org)
  • The most common way to collect stem cells from adults is by a peripheral blood stem cell donation. (cornellbmt.org)
  • Click here for translated materials on marrow donation. (cinj.org)
  • Follow this true story of a former NCI employee, Serena Marshall, as she takes you through her blood stem cell donation experience at the National Institutes of Health Clinical Center in Bethesda, MD. (cinj.org)
  • Blood, which requires extraction through apheresis, wherein blood is drawn from the donor (similar to a blood donation), and passed through a machine that extracts the stem cells and returns other portions of the blood to the donor. (wikipedia.org)
  • proliferation
  • After the four-day treatment, normal T cells are repopulated by homeostatic proliferation. (wikipedia.org)
  • MicroRNA-155 regulates the proliferation and growth of WM cells in vitro and in vivo, by inhibiting MAPK/ERK, PI3/AKT, and NF-κB pathways. (wikipedia.org)
  • progenitor
  • Stem and progenitor cells can be taken from the pelvis, at the iliac crest, using a needle and syringe. (wikipedia.org)
  • In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. (wikipedia.org)
  • In the strictest sense, this requires stem cells to be either totipotent or pluripotent-to be able to give rise to any mature cell type, although multipotent or unipotent progenitor cells are sometimes referred to as stem cells. (wikipedia.org)
  • Unipotent cells can produce only one cell type, their own, but have the property of self-renewal, which distinguishes them from non-stem cells (e.g. progenitor cells, which cannot self-renew). (wikipedia.org)
  • Healthy adult brains contain neural stem cells which divide to maintain general stem-cell numbers, or become progenitor cells. (wikipedia.org)
  • In healthy adult laboratory animals, progenitor cells migrate within the brain and function primarily to maintain neuron populations for olfaction (the sense of smell). (wikipedia.org)