Stem cells bacterial artificial clone cells. Medical search. Frequent questions

They described two patients with PNH with an acquired rearrangement of chromosome 12 affecting the HMGA2 gene, which encodes a chromatin remodeling protein, in the PIGA mutant cells [ 12 ]. (annexpublishers.co)
To produce the loss of function mouse model for ZFYVE27, we employed a novel Bacterial Artificial Chromosome (BAC) mediated homologous recombination method to generate the knockout construct in C57BL/6 background. (hsp-info.de)
We found that Dusp4 loss alone is insufficient in mediating tumorigenesis, but alternatively converges with loss in Trp53 and MYC amplification to induce tumorigenesis primarily through chromosome 5 amplification, which specifically upregulates Dbf4 , a cell cycle gene that promotes cellular replication by mediating cell cycle checkpoint escape. (biomedcentral.com)
They are not part of the main chromosome of the cell, but they can replicate independently and carry genes that may confer some advantages to the host organism. (stemcelldaily.com)

Bacterial Artificial Chromosomes (BACs) are ultra-low copy vectors that can hold up to 300 kb of genomic fragments, making them ideal vectors for the introduction of entire genes including the regulatory regions into the rat genome. (appliedstemcell.com)
Aneuploidy is an abnormality in the number of chromosomes in a cell due to loss or duplication. (genome.gov)

Somatic, inactivating PIGA mutations in haematopoietic stem cells, followed by an unknown autoimmune selection process in favor of the mutated clone, are thought to be important events in the pathogenesis of paroxysmal nocturnal hemoglobinuria (PNH). (annexpublishers.co)
PNH clones are present in a majority of patients with aplastic anemia, which is consistent with the strong immune component in the pathogenesis of this disease [ 7-9 ]. (annexpublishers.co)

Biochemically, PNH is a consequence of nonmalignant clonal expansion of hematopoietic stem cells with somatic mutation of PIGA [ 2 , 3 ], and mutant, inactive PIGA explains the deficiency of glycosyl phosphatidylinositol-anchored proteins [ 4 ]. (annexpublishers.co)

Stable expression of the bicistronic transcript allows the monitoring of a variety of cellular processes (such as differentiation in primary or stem cells), without the transgene silencing associated with CMV promoters. (biofeng.com)

Paneth cells in farm animals and their antimicrobial peptides (AMPs) are susceptible to multiple factors such as dietary nutrients and intestinal infection. (biomedcentral.com)
FPR −/− mice also had increased bacterial load in spleen and liver 2 d after infection, which is before development of a specific cellular immune response, suggesting a defect in innate immunity. (silverchair.com)
This study specifically examined for C.difficile which is a potentially life threatening bacterial infection that often spreads in hospital settings. (worldhealth.net)
This laboratory pursues several lines of investigation to understand how T cells contribute to autoimmune diseases and protection from infection, and how to modulate T cell immunity for therapeutic purposes in humans. (utsa.edu)

N -formylpeptides derive from bacterial and mitochondrial proteins, and bind to specific receptors on mammalian phagocytes. (silverchair.com)
Mitochondria are also platforms for antiviral signalling2 and, due to their bacterial origin, mtDNA and other mitochondrial components trigger innate immune responses and inflammatory pathology2,3. (regenerativemedicine.net)

Alternatively, you can choose to have us do the BAC modification strategy and cloning , and you can do the pronuclear injections and transgenic rat screening yourself. (appliedstemcell.com)
Transgenic plants expressing an artificial target mimic directed against miR396 (MIM396) with a decrease in the endogenous microRNA GANT61 Stem Cells & Wnt inhibitor activity or plants expressing miR396-resistant copies of several GRFs are less sensitive to this inhibition. (hsp70inhibitor.com)
After confirmation of transgenesis using PCR amplification of the rol A (320bp), rol B (400bp) and rol C (600bp) genes, metabolite profiles indicated a high level of Natural Product Library in vitro variability between the different transgenic clones but these had more compounds compared to non-transgenic control cultures. (hsp70inhibitor.com)

Clovibactin, isolated from soil bacteria, targets the cell wall precursor molecules lipid II, lipid III and undecaprenyl phosphate (C55PP), all of which have a pyrophosphate group in common. (bioworld.com)
Examples of these functions might include interaction with host cells at particular times of day, such as timed release of neurotransmitters produced by the bacteria, or interactions with other bacteria such as antifungal production triggered by a meal rich in sugar. (sciencedaily.com)
For example, plasmids can be used to produce recombinant proteins, such as insulin or human growth hormone, in bacteria or yeast cells. (stemcelldaily.com)

Here we examine the success rate of methods and data for differentiation by testing the ability of nine computational methods (CellNet, GarNet, EBseq, AME, DREME, HOMER, KMAC, diffTF and DeepAccess) to discover and rank candidate factors for eight target cell types with known reprogramming solutions. (nature.com)
MDS affects hematopoiesis at the stem cell level, as indicated by cytogenetic abnormalities, molecular mutations, and morphologic and physiologic abnormalities in maturation and differentiation of one or more of the hematopoietic cell lines. (medscape.com)

The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. (vet-ebooks.com)
UC San Diego researchers led by Jeff Hasty, a professor of bioengineering and biology and member of the UC San Diego Center for Microbiome Innovation, describe a new method, which involves cutting circular pieces of bacterial DNA called plasmids, effectively destroying the DNA and turning off regulation. (sciencedaily.com)
Such was the wording of many newspaper headlines introducing the story that The J. Craig Venter Institute had succeeded in constructing the first self-replicating bacterial cell as part of their research program in 'Synthetic Biology' in May 2010. (digitalmethods.net)
Since Haberlandt's original assertions, methods for tissue and cell culture have been realized, leading to significant discoveries in biology and medicine. (wikipedia.org)
The Hsieh laboratory is a neural stem cell biology laboratory that focuses on 4 major areas: (1) epilepsy-in-a-dish, (2) 3D cerebral organoids, (3) patient recruitment, and (4) mechanisms of adult neurogenesis. (utsa.edu)
Her work lies at the boundaries of biotechnology, DIY biology, genetic manipulation, bacterial colonies and biomaterials to raise awareness of the ethical and social impact of genetic manipulation and biotechnologies. (clotmag.com)

A new method for controlling gene expression across bacterial colonies has been invented by researchers. (sciencedaily.com)
Researchers at the University of California San Diego have invented a new method for controlling gene expression across bacterial colonies. (sciencedaily.com)

Since these early inventions, Hasty and his team have shown how engineered cellular oscillations can be synchronized within a bacterial colony using plasmids, synthetically designed by the researchers themselves. (sciencedaily.com)
Plasmids have been widely used in biotechnology and genetic engineering, as they can be manipulated to introduce, modify, or delete specific genes in the host cell. (stemcelldaily.com)
Plasmids often carry genes that confer some advantage to the host cell, such as antibiotic resistance, virulence factors, or metabolic capabilities. (stemcelldaily.com)
Compatibility of plasmids - this refers to the ability of two different plasmids to coexist in the same bacterial cell. (stemcelldaily.com)
Plasmids are small, circular, double-stranded DNA molecules that are distinct from the chromosomal DNA of the host cell. (stemcelldaily.com)
Plasmids can vary in size from 1 kb to 200 kb, and they can exist in different species and get transferred from one cell to another. (stemcelldaily.com)
Plasmids have certain essential elements that enable them to replicate and maintain themselves in the host cell. (stemcelldaily.com)

have recently sequenced the exome of affected cells in 12 PNH patients, and found a complex pattern of clonal evolution denoted by shared and distinct mutations in subclones, but not a single recurrent mutation besides PIGA [ 19 ]. (annexpublishers.co)
Proteome analysis with artificial intelligence has made it possible to create a catalog of all possible missense mutations in the human genome to predict diseases. (bioworld.com)
Several laboratories are investigating strategies to address other mutations and uses beyond non-small cell lung cancer (NSCLC) and colorectal cancer. (bioworld.com)
DUSP4 alterations lead to hyperactivation of MAPK signaling in many cancers, including breast cancer, which often harbor mutations in cell cycle checkpoint genes, particularly in TP53. (biomedcentral.com)
This study identifies a novel mechanism for breast tumorigenesis implicating Dusp4 loss and p53 mutations in cellular acquisition of Dbf4 upregulation as a driver of cellular replication and cell cycle checkpoint escape. (biomedcentral.com)
We find that together with loss-of-function mutations in p53 and, to some degree, potentiated by cMyc overexpression, Dusp4 deletion aids in cell cycle checkpoint escape while simultaneously potentiating hallmarks of replicative stress, including multinucleation and Chk1 phosphorylation. (biomedcentral.com)
The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. (biorxiv.org)

8. Hailong Wang, Zhen Li, Ruonan Jia, Yu Hou, Jia Yin, Xiaoying Bian, Aiying Li, Rolf Müller, A Francis Stewart, Jun Fu & Youming Zhang (2016) "A concerted pipeline for direct cloning of biosynthetic gene clusters and engineering for heterologous expression" Nature Protocols 11(7): 1175-90. (sdu.edu.cn)

The discovery of this new class of SSCs is based on the conjunction of evidence from unbiased single-cell molecular profiling and functional dissection of the BMSC lineage hierarchy using in vivo cell lineage analysis. (nature.com)
Experts theorized that this molecular brake prevents uncontrolled nerve cell growth once the CNS is mature, as a way of stabilizing the complex network. (scientificamerican.com)

We explain methods to sub-clone large genomic inserts into gene expression vectors. (ox.ac.uk)
The circuit works by using a small molecule, known as AHL, to coordinate gene expression across a colony of bacterial cells. (sciencedaily.com)

Transcription factor over-expression is a proven method for reprogramming cells to a desired cell type for regenerative medicine and therapeutic discovery. (nature.com)
And even then, it seems unlikely that countries such as Britain, which fund and support therapeutic cloning, would alter their research programmes. (bioedonline.org)

Advanced Cell Technology (ACT), a stem cell biotechnology company in Worcester, Massachusetts, showed the potential for cloning to contribute to conservation efforts. (asu.edu)

Cells expressing AcGFP1can be detected by flow cytometry or fluorescence microscopy 24 hours after transfection. (biofeng.com)

Firstly, we identified two BAC genomic clones (RPCIB731C16470Q2 and RPCIB731A01447Q2) from the mouse genomic DNA library RPCI-23, which is derived from the C57BL/6 mouse strain containing full genomic sequence of Zfyve27 and 50 kb flanking sequence from either end of the gene. (hsp-info.de)

Consequently, at intensities that can induce DNA damage in Arabidopsis plants, UV-B radiation limits leaf growth by inhibiting cell division in proliferating tissues, a process mediated by miR396 and GRFs. (hsp70inhibitor.com)
Tissue culture commonly refers to the culture of animal cells and tissues, with the more specific term plant tissue culture being used for plants. (wikipedia.org)
[12] He suggested that the potentialities of individual cells via tissue culture as well as that the reciprocal influences of tissues on one another could be determined by this method. (wikipedia.org)
It enables the handling of blood, respiratory samples, tissues, and cultured cells with input volumes up to 1 mL. (genengnews.com)
Therefore, we propose that damage to and subsequent release of mtDNA elicits a protective signalling response that enhances nDNA repair in cells and tissues, suggesting that mtDNA is a genotoxic stress sentinel. (regenerativemedicine.net)

It is well-described that leptin receptor (LepR) + perivascular stromal cells provide a major source of bone-forming osteoblasts in adult and aged bone marrow. (nature.com)
These Fgfr3-creER -marked endosteal stromal cells contribute to a stem cell fraction in young stages, which is later replaced by Lepr-cre -marked stromal cells in adult stages. (nature.com)
3. Gulce Itir Percin, Jiri Eitler, Andrea Kranz, Jun Fu, Jeffrey W. Pollard, Ronald Naumann & Claudia Waskow (2018) "CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages" Nature Communications . (sdu.edu.cn)
Dolly was the first mammal cloned from an adult cell taken from the mammary gland of a 6-year-old Finn Dorset sheep and an egg cell from a Scottish Blackface sheep. (bioworld.com)
SSCs are adult-tissue stem cells in the mammalian testis that balance self renewing and differentiating fate decisions to give rise to and sustain the entire spermatogenic lineage. (utsa.edu)

The researchers reasoned that the method could be used to regulate an entire suite of genes and promoters, and tested their idea using a previously constructed circuit to produce sustained cycling of DNA plasmid concentration across a colony of E. coli cells. (sciencedaily.com)
Because AHL is small enough to diffuse between cells and turn on the promoter in neighboring cells, the genes activated by it would also be produced in high amounts, leading to a phenomenon known as quorum sensing. (sciencedaily.com)
Interestingly, replication stress in Brca2-null cells activates p53 and the expression of its target genes, including senescence-inducing Ink4/Arf. (biomedcentral.com)

Expression of the bicistronic transcript is driven by the human elongation factor 1 alpha (EF1α) promoter, which continues to be constitutively active even after stable integration of the vector into the host cell genome. (biofeng.com)
Stable, constitutive expression of the bicistronic transcript is driven by the EF1α promoter (PEF1α), which continues to be constitutively active even after vector integration into the host cell genome (3).The vector backbone also contains an SV40 origin for replication in mammalian cells expressing the SV40 large T antigen, a pUC origin of replication for propagation in E. coli, and an f1 origin for single-stranded DNA production. (biofeng.com)

The intestinal epithelium consisting of a single layer of epithelial cells plays an important role in absorbing the digested dietary nutrients and separating the large amounts of microorganisms in the intestinal lumens from the lamina propria of intestine [ 7 ]. (biomedcentral.com)
As a type of long-lived epithelial cells, Paneth cells possess approximately one-month lifespan in small intestine [ 11 ]. (biomedcentral.com)
Using a genetically engineered mouse model, we generated mammary-specific Dusp4 -deleted primary epithelial cells to investigate the necessary conditions in which DUSP4 loss may drive breast cancer oncogenesis. (biomedcentral.com)

They are extra chromosomal DNA fragments present in the cell. (stemcelldaily.com)

The bone marrow contains various populations of skeletal stem cells (SSCs) in the stromal compartment, which are important regulators of bone formation. (nature.com)
These Fgfr3 + stem/stromal cells with OCT identities are abundant in the young bone marrow and depleted in the old bone marrow, denoting their transitional nature. (nature.com)
The term "transitional" emphasizes the unique feature of these cells that are particularly abundant in the young bone marrow. (nature.com)
Bone marrow cells display aberrant morphology and maturation (dysmyelopoiesis), resulting in ineffective blood cell production. (medscape.com)
MDS develops when a clonal mutation predominates in the bone marrow, suppressing healthy stem cells. (medscape.com)

Recently, a second clonal event involving the HMGA2 gene was reported in some PNH cases, and over expression of this gene was postulated to promote proliferation of the mutated clone. (annexpublishers.co)
Unlike dysplastic clones in myelodysplastic syndrome (MDS), which harbour intrinsic defects that predispose the cells to clonal evolution, external factors, such as pressure exerted by the immune system, have for a long time been speculated to be the main causes for clonal escape in PNH [ 5 ]. (annexpublishers.co)
In addition, the vector allows efficient flow cytometric detection of stably or transiently transfected mammalian cells expressing AcGFP1 and a protein of interest, without time-consuming drug and clonal selection. (biofeng.com)

results in inhibition of cell proliferation, and this outcome is independent of the UV-B photoreceptor UV resistance locus 8, as well as ATM AND RAD3-RELATED and the mitogen-activated protein kinase MPK6, but is dependent on MPK3. (hsp70inhibitor.com)
As the disease progresses and converts into leukemia, further gene mutation occurs, and a proliferation of leukemic cells overwhelms the healthy marrow. (medscape.com)

pEF1α-IRES-AcGFP1 is designed to simultaneously and constitutively express a protein of interest and AcGFP1 in mammalian cells. (biofeng.com)
pEF1α-IRES2-AcGFP1 can be introduced into mammalian cells using any standard transfection method. (biofeng.com)

That's important because greater bacterial diversity is generally associated with better health, Wang notes. (worldhealth.net)

These countries argue that cloning for research should be allowed because stem cells grown from cloned embryos might lead to cures for countless diseases. (bioedonline.org)
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. (wikipedia.org)
Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown free floating in a medium as a suspension culture . (wikipedia.org)

To generate loss of function knockout mouse we will use gene-targeting technology to disturb the endogenous Zfyve27 gene of the mouse through homologous recombination in embryonic stem (ES) cells. (hsp-info.de)

Without doubt, 20th-century technologies will continue to develop, and disciplines like robotics, artificial intelligence, nanotechnology and quantum computers will undoubtedly continue to confront us with all kinds of welcome and less welcome surprises. (demul.nl)

Cellular immunology, T cell immunity, autoimmune diseases: The immune system plays a fundamental role in the defense against microbial pathogens. (utsa.edu)

Ganglia are clusters of nerve cells, from which nerve fibers emerge. (asu.edu)
In 1907 the zoologist Ross Granville Harrison demonstrated the growth of frog embryonic cells that would give rise to nerve cells in a medium of clotted lymph . (wikipedia.org)
Finally, however, science offers glimmers of hope that nerve cells in the spinal cord and brain could someday regenerate. (scientificamerican.com)
In recent years, however, improved medical technology has shown that after a spinal cord is cut, nerve cells do begin to extend new fingers, called axons, which could carry signals across the gap. (scientificamerican.com)

Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. (vet-ebooks.com)
Given the previously reported role of DUSP4 as a p53 target, a potential cell cycle checkpoint, and in mediating senescence downstream of replication stress, we hypothesized that DUSP4 may be a critical oncogenic driver in breast cancer. (biomedcentral.com)
This means that they do not depend on the replication machinery of the host cell and can make copies of themselves using their own origin of replication (OR) and enzymes. (stemcelldaily.com)

In addition to immune cells such as macrophages and dendritic cells, Paneth cells are considered as an essential part of intestinal innate immunity due to their multiple functions such as antimicrobial peptide (AMP) secretion and ISC support [ 11 ]. (biomedcentral.com)

He proposed that this transfer was due to a circular DNA molecule that could move from one cell to another. (stemcelldaily.com)
Thousands of copies of the circular mtDNA are present in most cell types that are packaged by TFAM into higher-order structures called nucleoids1. (regenerativemedicine.net)

A bacterial promoter upstream of the cassette drives expression of the kanamycin resistance gene in E. coli. (biofeng.com)

Further, Fgfr3 + endosteal stromal cells give rise to aggressive osteosarcoma-like lesions upon loss of p53 tumor suppressor through unregulated self-renewal and aberrant osteogenic fates. (nature.com)

In addition, mtDNA stress in TFAM-deficient mouse melanoma cells produces tumours that are more resistant to doxorubicin in vivo. (regenerativemedicine.net)

MDS may involve one, two, or all three myeloid hematopoiesis cell lineages-erythrocytic, granulocytic, megakaryocytic-depending on the subtype and stage of the disease. (medscape.com)

Both extrinsic and intrinsic mechanisms determine distinct daughter cell fates after ACD. (elifesciences.org)

The reference to horror-flicks and divine intervention in these headlines indicates that it is not just new types of artificial organisms that will be brought to life in the next decade. (digitalmethods.net)

In practice, the term "cell culture" now refers to the culturing of cells derived from multicellular eukaryotes , especially animal cells, in contrast with other types of culture that also grow cells, such as plant tissue culture , fungal culture, and microbiological culture (of microbes ). (wikipedia.org)
Copy number - the copy number refers to the number of copies of plasmid present in the bacterial cell. (stemcelldaily.com)
Resistance refers to bacterial defense mechanisms used to evade the effects of an antibiotic. (cdc.gov)

Cell culture techniques were advanced significantly in the 1940s and 1950s to support research in virology . (wikipedia.org)

Of note, we define OCT identities as a state with some characteristics of both osteoblasts and chondrocytes, instead of cell-type plasticity between osteoblasts and chondrocytes. (nature.com)
Overall, our findings indicate that Fgfr3 + endosteal stem/stromal cells with OCT identities dictate active and aggressive osteogenesis, identifying these cells as an important regulator of long-term bone homeostasis. (nature.com)

Cellix' VenaFlux™ platform, reported to be the first semiautomated, high-throughput microfluidic cell-based assay system, measures cells' adhesion to antibody-coated or endothelial cell cultured microchannels, mimicking physiological flow. (genengnews.com)

Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer. (lu.se)

The field was firmly established in 2000, with the description of synthetic biological circuits in which parts of a cell are designed to perform functions, similar to the way an electronic circuit works. (sciencedaily.com)
However, Paneth cells in the small intestine of livestock, especially their biological functions, are poorly understood. (biomedcentral.com)

Caenorhabditis elegans represents a valuable model for investigating ACD, given its invariant cell lineage and conserved mechanisms of ACD. (elifesciences.org)

RNA-seq following PCR-based sorting reveals rare cell transcriptional signatures. (nature.com)
Until now, methods for controlling or programming bacterial cells involved transcriptional and post-transcriptional regulation. (sciencedaily.com)

Thermo Fisher Scientific introduced the KingFisher Flex magnetic particle processor for DNA/RNA, protein, and cell purification from virtually any source. (genengnews.com)
The AutoReact™ mini-bioreactor system from Hudson Control Group is ideal for clone screening and selection, protein production for research applications, as well as media development and improvement for both research and manufacturing applications, according to Phil Farrelly, president. (genengnews.com)
In a cell, antisense DNA serves as the template for producing messenger RNA (mRNA), which directs the synthesis of a protein. (genome.gov)

In small intestine, Paneth cells are well known for their regulation of intestinal microbiota and intestinal stem cells (ISCs). (biomedcentral.com)

A newly discovered antibiotic has been shown to block the synthesis of bacterial cell walls via immutable targets, raising the prospect of a class of drugs that will not lose effect through the development of antimicrobial resistance. (bioworld.com)
They are extrachromosomal and not essential for the survival of the cell, but they may confer some advantages such as antibiotic resistance or virulence. (stemcelldaily.com)
This is a gene that confers resistance to a certain antibiotic or toxin, which helps in identifying and selecting the cells that contain the plasmid. (stemcelldaily.com)

This means that they are not part of the main genetic material of the cell and can exist independently of it. (stemcelldaily.com)

As one of the most important immune organs, intestine possesses more than 70% of bodily immune cells and immunoglobulin A (IgA) secreted in the intestine [ 3 ]. (biomedcentral.com)

Fig. 3: Use of histone mark and EP300 annotation does not significantly affect transcription factor recovery in liver cells. (nature.com)
Normalized area under rank recall curve values for all methods are available in Supplementary Tables 2 - 6 and for epigenomic marks of liver cells in Extended Source Data Fig. 3 . (nature.com)

Asymmetric cell divisions (ACDs) generate two daughter cells with identical genetic information but distinct cell fates through epigenetic mechanisms. (elifesciences.org)
We suggest that asymmetric segregation of V-ATPase may cause distinct acidification levels in the two daughter cells, enabling asymmetric epigenetic inheritance that specifies their respective life-versus-death fates. (elifesciences.org)

In the build-up to the debate, a group of patient and medical research advocates yesterday pleaded with UN delegates not to forbid the cloning of human embryos for medical research. (bioedonline.org)
This includes both reproductive cloning to make babies, and the creation of human embryos for use in medical research. (bioedonline.org)
This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. (vet-ebooks.com)
To promote a comprehensive understanding of Paneth cells in farm animals, this review summarizes the current knowledge of Paneth cells in farm animals such as pig, cattle and sheep, and proposes the future directions for research on Paneth cells in the reviewed animals. (biomedcentral.com)
This vaccine was made possible by the cell culture research of John Franklin Enders , Thomas Huckle Weller , and Frederick Chapman Robbins , who were awarded a Nobel Prize for their discovery of a method of growing the virus in monkey kidney cell cultures. (wikipedia.org)

In 2000 ACT researchers in the United States cloned a gaur (Bos gaurus), an Asian ox with a then declining wild population. (asu.edu)
The researchers used cryopreserved gaur skin cells combined with an embryo of a domestic cow (Bos taurus). (asu.edu)
Now, the team is adding a new tool to the Synthetic Biologist's toolbox -- a "master clock" of sorts that will allow researchers to coordinate subprocesses in bacterial cells. (sciencedaily.com)
We offer single-platform, continuous-flow, cell-based assays on a microchip that act like a human capillary, providing real-life physiological conditions and enabling researchers to look at the side effects of drugs before getting to clinical trials," explained Julia Umlauf, sales representative. (genengnews.com)

These names reflect their ability to transfer from one cell to another through a process called conjugation, which involves the formation of a pilus (a thin tube-like structure) between two cells and the transfer of a copy of the plasmid. (stemcelldaily.com)

Pleuropulmonary manifestations were investigated and pleural and bronchoalveolar cells were characterized by RNA analysis, imaging and/or flow cytometry focusing on macrophages. (bvsalud.org)

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