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  • HSCT
  • Therefore, HLA-matched unrelated HSCT, HLAmismatched related HSCT, and unrelated cord blood transplantation have been investigated. (go.jp)
  • Two- or three-antigen mismatched related HSCT without ex vivo T-cell depletion has been investigated in Japan using a variety of strategies including in vivo T-cell depletion using anti-thymocyte globulin or alemtuzumab, and its safety has become close to that of HLA-matched HSCT. (go.jp)
  • However, the appropriate choice of these strategies as well as the difference in HSCT outcome with cord blood transplantation has not been clarified. (go.jp)
  • We also examined the potential use of CMV-specific CD8 + T cell numbers and functional and cytolytic responses in two autologous HSCT recipients treated for multiple myeloma. (hindawi.com)
  • Clinical cytomegalovirus (CMV) is a significant cause of morbidity and mortality in patients who have undergone allogeneic hematopoietic stem cell transplantation (HSCT) or solid organ transplantation (SOT), despite the availability of antiviral treatments [ 1 - 3 ]. (hindawi.com)
  • Previous studies have shown that CMV disease develops in more than half of HSCT patients lacking detectable anti-CMV T-cell responses [ 12 ]. (hindawi.com)
  • Overall survival in the RCT was reported not statistically significantly different between autologous HSCT following HDCT versus SDCT. (bmj.com)
  • Conclusions Overall survival in patients with locally advanced or metastatic NRSTS was not statistically different after autologous HSCT following HDCT compared with SDCT in a single RCT with a total of 83 patients. (bmj.com)
  • stimulation
  • In addition, in vitro peptide stimulation followed by intracellular staining for IFN- γ and CD107a/b is a well-established method to measure the functional and cytotolytic characteristics of these cells correspondingly [ 9 , 15 ]. (hindawi.com)
  • perfusion
  • Preclinical studies have indicated that human CD34 + stem cells induce neovascularization in ischemic myocardium, which enhances perfusion and function. (ahajournals.org)