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  • progenitor cells
  • Additionally, it now appears possible to identify and isolate specific ESC-derived cardiac progenitors (ESC-CPs) ( 9 - 11 ), opening the possibility of using progenitor cells for cardiac cell therapy, as has been explored using pancreatic endoderm progenitors for the generation of insulin responsive islet-like cells ( 12 , 13 ). (pnas.org)
  • germ cells
  • In this review, we consider the mRNAs and novel genes with unique expression and imprinting patterns that were discovered using systems biology approaches with primate pluripotent stem and germ cells. (biomedcentral.com)
  • pluripotent cells
  • Importantly, although multiple CMs and CPs can be generated from pluripotent cells, it is not clear which specific cell types will be the most effective in treating cardiac disease, or what additional factor(s) may be important for functional cell integration. (pnas.org)
  • tissue
  • These include identifying the best cells to use for reparative fusion, determining the best route of introducing these cells into the desired tissue, discovering methods to increase the incidence of cell fusion, and ensuring the functionality of the resulting fusion products. (springer.com)
  • It is with this limitation in mind that we, herein, explore the utility of an engineered heart tissue (EHT) as a predictive test-bed for functional cell integration. (pnas.org)
  • Numerous types of stem cells have been isolated from dental tissue, such as dental pulp stem cells (DPSCs), stem cells isolated from human pulp of exfoliated deciduous teeth (SHED), periodontal ligament stem cells (PDLSCs), stem cells from apical papilla (SCAPs), and dental follicle cells (DFCs). (stemsave.com)
  • All these cells can regenerate the tissue of tooth. (stemsave.com)
  • The main objective of cell-based therapies is to repopulate the damaged tissue with functional cells, with the final goal that these cells will integrate with the remaining functional native cells and contribute to the recuperation of the lost function. (stembook.org)
  • Stem cell therapy [ 1 ] and tissue engineering [ 2 ] are two new approaches to improve the male fertility. (biomedcentral.com)
  • spinal
  • Demyelination contributes to loss of function after spinal cord injury, and thus a potential therapeutic strategy involves replacing myelin-forming cells. (jneurosci.org)
  • Here, we undertook a proof of concept experiment to determine the feasibility and efficacy of using human stem cell derivatives to promote remyelination and functional recovery in the injured adult rat spinal cord. (jneurosci.org)
  • High-purity OPCs were then transplanted into spinal cord injury (SCI) sites in rats 7 d or 10 months after injury. (jneurosci.org)
  • The leukemia cells can spread outside the blood to other parts of the body, including the central nervous system (brain and spinal cord), skin, and gums. (healthbase.com)
  • vivo
  • In vivo and in vitro studies point out that decellularized scaffold was non-toxic and performed a good platform for cell division. (biomedcentral.com)
  • peripheral
  • An IA delivery into a cerebral artery such as the carotid or middle cerebral artery has the advantage of selective deposition of cells to the infarcted region without first having to pass through the venous system and peripheral organs. (ajnr.org)
  • Illustrative Case 1 A 32-year-old male with an underlying disease of acute myeloge- nous leukemia underwent a matched peripheral blood stem cell trans- plant from his brother. (elearningcasestudies.ru)
  • Transforming
  • Previously, the researchers discovered that a protein called transforming growth factor-beta (TGF-beta), which accumulates as brains age, reduces the number of neuronal precursor cells in the brains of mice. (actionalz.org)
  • liver
  • The doctors decided to give her a new vein instead of a liver transplant or giving her a vein from her own body, Associated Press reported. (slashdot.org)
  • Tests such as a complete blood count , liver and kidney function panels, and blood chemistries can give important information about the number of normal blood cells in the body and how well the organs are working. (kidshealth.org)
  • Mark Thomas, MD, an assistant professor and transplant surgeon at the University of Cincinnati (UC) is credited with performing the first pediatric laparoscopic liver// surgery. (bio-medicine.org)
  • This patient's symptoms had been dismissed as such for several months before physicians confirmed he had hepatoblastoma of the liver, a type of cancer that starts in the organ's cells (hepatocytes) and develops into one or multiple tumors. (bio-medicine.org)
  • therapy
  • Our results support the use of EHT as a model system to accelerate development of cardiac cell therapy strategies. (pnas.org)
  • We hypothesized that analysis of the changes in the molecular and electrophysiological properties of EHT upon test cell injection could provide insight into the potential (or limitations) of different test cell populations and conditions for cardiac cell therapy. (pnas.org)
  • These studies suggest that DFSC-based cell therapy may provide pro-tolerogenic immunomodulation relevant to allergic diseases such as asthma. (stemsave.com)
  • This type of therapy uses high-energy X-rays to kill cancer cells. (ahealthyme.com)
  • The purpose of postremission therapy is to kill any remaining leukemia cells that may not be active but could begin to regrow and cause a relapse. (healthbase.com)
  • ESCs
  • Therefore, the ESCs are closely related to the inner cell mass, from which, via post-implantation development, the embryo and fetus form. (biomedcentral.com)
  • catheters
  • however, a key translational question is whether cells are harmed by catheters and the associated chemicals, such as heparin, and contrast agents used in IA procedures. (ajnr.org)
  • Numerous
  • The mesenchymal cells from the group with complement deposition were less numerous, dysfunctional, had a reduced capacity to proliferate, and showed increased apoptosis as well as abnormal secretion of interleukin-1β and C-X-C motif chemokine ligand 12. (haematologica.org)
  • adult
  • Adding to what you have said OYWK: the stem cells came from an adult whose genome had already expressed the mutation that made this possible to begin with. (theknightshift.com)
  • confers
  • This following a stem cell transplant from a person carrying a unique mutation that confers natural resistance to the virus that causes AIDS. (theknightshift.com)
  • Transfer of the bacterial gene for cytosine deaminase to mammalian cell confers lethal sensitivity to 5-fluorocytosine: A negative selection system," Proc. (patentgenius.com)
  • methodologies
  • At the same time, many methodologies to generate iPS cells have been reported, and are comprised mainly of viral methods and non-viral methods. (jove.com)
  • grown
  • Now that question has been answered, as Weizmann's Dr. Karina Yaniv has revealed how the system develops in the embryo, and - in a world's first - grown lymphatic cells in the lab. (weizmann-usa.org)
  • Remission
  • The goal is to kill the cancer cells and put the cancer into remission. (ahealthyme.com)
  • I believe it is by the grace of God that the doctors I have working with me are actually well aware of this issue and are confident they know the best way to attack it in order to lengthen the remission I gain from my stem cell trans-plant. (blogspot.com)
  • abnormal
  • These are medicines that target abnormal proteins, such as those caused by gene changes in the AML cells. (ahealthyme.com)
  • These abnormal white cells are not fully developed and do not work properly. (sa.gov.au)
  • In this procedure, the doctor inserts a needle into a large bone, usually the hip, and removes a small amount of bone marrow to examine it for abnormal cells. (kidshealth.org)
  • cancer
  • It has been explained that trans fatty acid or trans fat are a major ingredient in diet that increases the risk of obesity and heart disease, and has also been linked to certain forms of cancer. (bio-medicine.org)
  • The treatment uses medicines to kill cancer cells. (ahealthyme.com)
  • cancer cells. (bioportfolio.com)
  • cancer cells from dividing so they stop growing or die. (bioportfolio.com)
  • I. Preparation of antihuman chorionic gonadotropin-carboxypeptidase G.sub.2 and cytotoxicity of the conjugate against JAR choriocarcinoma cells invitro," British Journal of Cancer 53: 377-384, 1986. (patentgenius.com)
  • contrast
  • IA-based delivery of cells to the brain is under investigation for stroke, but it is unknown whether cells are injured as a result of being injected through a catheter or exposed to iodinated contrast medium or solutions containing heparin. (ajnr.org)
  • In contrast, when OPCs were transplanted 10 months after injury, there was no enhanced remyelination or locomotor recovery. (jneurosci.org)