Myeloproliferative DisordersReceptor, Fibroblast Growth Factor, Type 1Chromosomes, Human, Pair 8Janus Kinase 2Primary MyelofibrosisPolycythemia VeraThrombocythemia, EssentialMyelodysplastic-Myeloproliferative DiseasesStem CellsBone Marrow NeoplasmsReceptors, ThrombopoietinThrombocytosisHematopoietic Stem CellsLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeLeukemia, Myelomonocytic, JuvenileMutationAnemia, RefractoryStem Cell TransplantationMyelodysplastic SyndromesEmbryonic Stem CellsProto-Oncogene Proteins c-cblSplenomegalyAdult Stem CellsPhiladelphia ChromosomeHematologic NeoplasmsJanus KinasesPluripotent Stem CellsHematopoietic Stem Cell TransplantationLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMegakaryocyte Progenitor CellsSTAT5 Transcription FactorLeukemia, Myeloid, AcuteBone MarrowHematologyCell ProliferationStem Cell NicheClonal EvolutionCell DifferentiationNeural Stem CellsInduced Pluripotent Stem CellsFusion Proteins, bcr-ablMyeloid Progenitor CellsBlast CrisisGene Knock-In TechniquesProtein Kinase InhibitorsMyelopoiesisMutation, MissenseAmino Acid SubstitutionMultipotent Stem CellsMesenchymal Stem Cell TransplantationMegakaryocyte-Erythroid Progenitor CellsMegakaryocytesDNA Mutational AnalysisAnemia, SideroblasticLeukemia, MyeloidCell Transformation, NeoplasticSignal TransductionStem Cell FactorMesenchymal Stromal CellsNeoplasmsCell LineageBone Marrow DiseasesHematopoiesis, ExtramedullaryProto-Oncogene ProteinsLeukemiaMice, Inbred C57BLBone Marrow CellsPoint MutationPhenotypeHematopoiesisDisease ProgressionCells, CulturedExonsPyrazolesStem Cell ResearchNeoplastic Stem CellsMice, TransgenicPlant StemsDNA-Binding Proteins