Stem cell by cloning somatic cell clone cells. Medical search. Frequent questions

Depending on the source, stem cells can be classified into two broad categories i.e. embryonic stem cells that are derived from embryos and non-embryonic stem cells that are derived from adult and fetal tissues. (benthamscience.com)
Under such circumstances, the idea of "therapeutic cloning" was proposed, indicating the generation of ESCs from SCNT embryos for therapeutic purpose. (benthamscience.com)
However, the derivation of human NT-ESCs goes with the destruction of clone embryos, leading to fierce ethical disputes. (benthamscience.com)
In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
In January 2006, Hwang's home research institution, Seoul National University, delivered a damning report about Hwang's work on cloned human embryos, concluding it was all based on fraudulent data. (nature.com)
Scientists have applied somatic cell nuclear transfer to clone human and mammalian embryos as a means to produce stem cells for laboratory and medical use. (asu.edu)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
These scientists destroyed the embryos and derived stem cell lines. (nationalrighttolifenews.org)
Most embryos…formed one or two pronuclei at the time of removal from TSA, whereas a slightly higher portion of embryos cleaved…suggesting that some SCNT embryos did not exhibit visible pronuclei at the time of examination… Most cleaved embryos developed to the eight-cell stage…but few progressed to compact morula…and blastocyst. (nationalrighttolifenews.org)
Activation of embryonic genes and transcription from the transplanted somatic cell nucleus are required for development of SCNT embryos beyond the eight-cell stage…Therefore, these results are consistent with the premise that our modified SCNT protocol supports reprogramming of human somatic cells to the embryonic state. (nationalrighttolifenews.org)
A story in News.Com.Au-which runs stories from several Australian newspapers celebrates the cloning breakthrough because it means no embryos are used in the process! (nationalrighttolifenews.org)
But it is an important step in research because it doesn't require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. (nationalrighttolifenews.org)
The Los Angeles Times has waded in to the junk biology game, assuring us that no embryos are threatened in human cloning-WHEN THE WHOLE POINT OF HUMAN CLONING IS TO CREATE AN EMBRYO! (nationalrighttolifenews.org)
And now Washington joins the infamous list with Senate Bill 5594, a thoroughly disingenuous piece of legislation that purports to outlaw the cloning of human beings, but by manipulating language and redefining terms, actually permits human cloning and gestation of the resulting cloned embryos through the ninth month. (cbc-network.org)
In the ongoing debate about cloning human embryos for research, and about destroying them in order to harvest their stem cells, it is important to keep some basic facts in mind. (actionlife.org)

One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
Somatic cell nuclear transfer (SCNT) is a technology applied in cloning, stem cell research and regenerative medicine. (asu.edu)
체세포 핵 치환 (Somatic-cell nuclear transfer, SCNT)은 난자 의 핵 을 제거한 후에, 체세포 의 핵을 이식하여 복제 를 하는 기술을 말한다. (wikipedia.org)
The American Medical Association (AMA) defines human cloning as genetically identical organism's production through a process of somatic cell's nuclear transfer (SCNT). (premiumessays.net)
SCNT refers to a process that entails transferring somatic cells of an existing organism into the oocyte where the nucleus came from (National Human Genome Research Institute Para 1). (premiumessays.net)
Once the SCNT is done, the cloning is over. (nationalrighttolifenews.org)
The cloning is completed when the SCNT is accomplished. (nationalrighttolifenews.org)
The primary cloning technique is called "somatic cell nuclear transfer" (SCNT). (cbc-network.org)
If the authors of this bill really meant what they appear to have written, their legislation would ban all human cloning, since as we have seen, biologically, a new human organism, that is, a new human being, comes into existence with the completion of SCNT. (cbc-network.org)
This is junk biology since implanting isn't the act of asexual reproduction: SCNT cloning is. (cbc-network.org)

After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
Last year, Hwang's team said it successfully cloned a human embryo from embryonic stem cells. (blogspot.com)
According to MBC, the scientist "maintains that Hwang's team fabricated data because in reality it failed to clone a somatic cell and instead used a frozen embryo from the hospital to make stem cells. (blogspot.com)
Park Se-pill, head of Seoul-based fertility clinic Maria Biotech, said the tests can silence Hwang's critics who have suggested the dog might be a twin created from a split embryo rather than a clone. (blogspot.com)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
Cloning also entails organs and tissues production through cell implantation in cultures with the real embryo that will be born. (premiumessays.net)
The embryo that is used to produce stem cells has an arguable moral status. (premiumessays.net)
As such, when a person opts to clone their embryo in order to produce stem cells that can be used for therapeutic purposes that will prolong life, they violate one of these moral principles which entail protecting human life as a duty. (premiumessays.net)
However, one may also wonder whether more weight should be accorded the second principle that prohibits embryo's use in generating stem cells because it violates value and respect for the embryo which is the start of a human being. (premiumessays.net)
creates a cloned embryo. (nationalrighttolifenews.org)
A cloned embryo-like a natural embryo-is an individual organism, a member of its (in this case, human) species. (nationalrighttolifenews.org)
After that, the question becomes not whether to clone, but what to do with the embryo that was created through the cloning process. (nationalrighttolifenews.org)
A little shot of electricity comes next, and if all goes well, a new human cloned embryo comes into being and begins to develop in the same way as a sexually created embryo. (cbc-network.org)
Cloning of a human being" means asexual reproduction by implanting or attempting to implant the product of nuclear transplantation [e.g., an embryo] into a uterus or substitute for a uterus with the purpose of producing a human being. (cbc-network.org)
increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
Normally, the embryo comes into being through sexual conception, in which the female egg cell is fertilized by a male sperm cell. (actionlife.org)
… "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
… "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)

Mouse nuclear transfer embryonic stem cells (NT-ESCs) were first established in 2000, and then proved to be able to differentiate either in vivo or in vitro, and give rise to individual tissues through germ line transmission or tetraploid complementation. (benthamscience.com)
For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
Hwang's stem cells should have been found to be nuclear transferred embryonic stem cells from patients' skin cells. (blogspot.com)
More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)
Use of somatic cel nuclear transfer to study meiosis in female cattle carrying a sex-dependent fertility-impairing X-chromosome abnormality. (uoguelph.ca)
It is the policy of Washington state that research involving the derivation and use of human embryonic stem cells, human embryonic germ cells, and human adult stem cells from any source, including somatic cell nuclear transplantation , is permitted upon full consideration of the ethical and medical implications of this research. (cbc-network.org)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)

To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)

These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
At that point - and this is important to understand - there is no more cloning to be done since a new human organism now exists. (cbc-network.org)
If the cloned human organism is to be experimented upon and destroyed, the process is often called "therapeutic cloning. (cbc-network.org)
Or to put it the other way around, cloning, not implantation, is what produces a new and distinct human organism. (cbc-network.org)
This is cloning, a process in which the body cell that donated the replacement nucleus supplies the chromosomes of the new human organism. (actionlife.org)
Whether the new organism is produced by fertilization or by cloning, each new human organism is a distinct entity. (actionlife.org)
XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
A clone is an organism that is a genetic copy of an existing one. (who.int)
Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)

By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) provide an accessible, genetically tractable, and homogenous starting cell population to efficiently study human blood cell development. (benitonovas.com)
But they showed, for the first time, that it is possible to create cloned embryonic stem cells that are genetically identical to the person from whom they are derived. (nationalrighttolifenews.org)

In 2001 researchers at Advanced Cell Technology in Worcester, Massachusetts, United States, reported that 24 successfully cloned Holsteins had been monitored from birth to the age of four. (wikipedia.org)
In 1958, John Gurdon, then at Oxford University, explained that he had successfully cloned a frog. (wikipedia.org)
A Korean institute Wednesday, Dec. 27, said that its DNA tests proved Prof. Hwang Woo-suk at Seoul National University (SNU) had successfully cloned a dog. (blogspot.com)

Stem cells are emerging as an important source of material for diseases in regenerative medicine. (benthamscience.com)
The study of biology of stem cells is the hallmark of the recent emerging field of regenerative medicine and medical biotechnology. (benthamscience.com)
Pluripotent stem cells hold promise in the field of regenerative medicine. (benitonovas.com)
The ability to induce pluripotent stem cells from committed, human somatic cells provides tremendous potential for regenerative medicine. (benitonovas.com)
The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)

That is what New Jersey legislators did when they passed and then Governor James McGreevey signed S-1909 last year, a law that was sold to the public as outlawing human cloning but which actually permits the creation of cloned human life, and its implantation and gestation up to and including the very moment prior to the emergence of the cloned baby from the birth canal. (cbc-network.org)

Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)

In 2000, Texas A&M University cloned a Black Angus bull named 86 Squared, after cells from his donor, Bull 86, had been frozen for 15 years. (wikipedia.org)
Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
The resulting cells were pluripotent and could be differentiated into insulin-producing beta cells to restore the function of the pancreas in the donor. (news-medical.net)
HumanPass Wednesday confirmed fingerprinting traces of Snuppy, Hwang's canine clone, matched those of its somatic cell donor, an Afghan hound named Tai, while they demonstrated disparate mitochondrial genotypes. (blogspot.com)
The nucleus of a body cell from the DNA donor is removed, and put into the place formerly occupied by the egg's nucleus. (cbc-network.org)
Allogeneic hematopoietic stem cell transplantation is curative but it requires a histocompatible donor and is associated with significant morbidity and mortality, so it is reserved for severe cases of PNH with aplastic anemia or transformation to leukemia. (medscape.com)

Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. (benitonovas.com)
Using genome-wide assays, we identify cancer-related epigenetic abnormalities that arise early during reprogramming and persist in induced pluripotent stem cell (iPS) clones. (benitonovas.com)
Pluripotent stem cells could provide an estimable source of T lymphocytes, but the therapeutic potential of human pluripotent stem cell-derived lymphoid cells generated to date remains uncertain. (benitonovas.com)
Moreover, even when high-purity single-cell sorting can be achieved, viability after sorting is often low to moderate, especially for cell types that are particularly sensitive to hydrodynamic stress or low-density culture conditions (e.g., primary cells or pluripotent stem cell lines). (nature.com)

The most famous clone was a Scottish sheep named Dolly. (medlineplus.gov)

The second way to reproduce is a strictly human invention - known as "asexual" reproduction - or more commonly, cloning. (cbc-network.org)

In 2001, scientists at Texas A&M University created the first cloned cat, CC (CopyCat). (wikipedia.org)
In May 2010, Got became the first cloned Spanish Fighting Bull, cloned by Spanish scientists. (wikipedia.org)
In July 2016 scientists at the National University Toribio Rodríguez de Mendoza in Chachapoyas, Peru cloned a Jersey cattle by handmade cloning method using cells of an ear of a cow. (wikipedia.org)
In the second half of the twentieth century, scientists learned how to clone organisms in some species of mammals. (asu.edu)
Scientists have used cloning technology to transform human skin cells into embryonic stem cells, an experiment that may revive the controversy over human cloning. (nationalrighttolifenews.org)
The method described on Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. (nationalrighttolifenews.org)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)

Gene, the first cloned calf in the world was born in 1997 at the American Breeders Service facilities in Deforest, Wisconsin, United States. (wikipedia.org)
These include hundreds of abnormal gene silencing events, patterns of aberrant responses to epigenetic-modifying drugs resembling those for cancer cells, and presence in iPS and partially reprogrammed cells of cancer-specific gene promoter DNA methylation alterations. (benitonovas.com)
Cell engineering through gene editing is fundamentally a two-step bioprocess. (nature.com)

The FT500 NK cells do not undergo any further alterations and after their derivation from the induced pluripotent stem cells (iPSCs), offering the possibility of a quicker, ready-made treatment. (benitonovas.com)

Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell (HSC) disease. (medscape.com)
Paroxysmal nocturnal hemoglobinuria (PNH) was previously classified as purely an acquired hemolytic anemia due to a hematopoietic stem cell mutation defect. (medscape.com)

A chronology of Woo Suk Hwang's stem-cell research. (nature.com)
Do our only cloned primates come from the lab of Woo Suk Hwang's colleague? (nature.com)
However, Korean television station MBC has conducted interviews with an unnamed member of Hwang's research team who says the cells were never cloned successfully. (blogspot.com)
After an investigative panel at SNU found last week that Hwang's team fabricated data for his purported exploit of making 11 tailor-made stem cells, his other works such as Snuppy were all cast under suspicion. (blogspot.com)
Only two of Hwang's 11 claimed stem-cell lines existed when he submitted his 2005 paper to the journal, Science, the university said on Dec. 23. (blogspot.com)
The stem cells in storage at Hwang's laboratories at the university were all derived from the fertility clinic MizMedi's blastocysts, which were generated by in vitro fertilization . (blogspot.com)

Somatic cells are cells that have gone through the differentiation process and are not germ cells. (asu.edu)

The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
Such "guidelines" will ensure that stem cell researchers are not treated poorly as was Hwang when he was eventually found guilty of falsifying his data. (lifeissues.net)
hero" is the right word for how Hwang Woo-suk is revered by the media -- and by a large section of the Korean public who have bought into the false promises of embryonic stem cell and cloning researchers. (blogspot.com)
A Korean television station whose investigative report was the nail in the coffin that prompted human cloning scientist Hwang Woo-suk to admit he lied about egg donations his researchers made says he may have lied about the results of his research as well. (blogspot.com)
Researchers are hopeful that the clinical trial can help determine which cancer patients could benefit the most from NK cell treatment. (benitonovas.com)
The researchers stopped well short of creating a human clone. (nationalrighttolifenews.org)
US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embryonic stem cells for the first time. (nationalrighttolifenews.org)
Researchers hope to use these cells to grow healthy tissue to replace injured or diseased tissues in the human body. (medlineplus.gov)

General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)

WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)

The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)

This paper gives an Islamic perspective on some of these advances, including abortion, in vitro fertilization, genetic engineering, cloning and stem cell research. (who.int)

A purebred Hereford calf clone named Chloe was born in 2001 at Kansas State University's purebred research unit. (wikipedia.org)
An Anatolian Grey bull (Efe) was cloned in Turkey in 2009 and four female calves from the same breed (Ece, Ecem, Nilüfer, Kiraz) in 2010 by the Scientific and Technological Research Council of Turkey (TÜBİTAK). (wikipedia.org)
A Boran cattle bull was cloned at the International Livestock Research Institute in Nairobi. (wikipedia.org)
Kuldip S. Sidhu , " Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside ", Bentham Science Publishers (2012). (benthamscience.com)
What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
This form of cloning is unrelated to stem cell research. (eurostemcell.org)
Such is the fate of two entire fields of academia intertwined in the current issue of human embryonic stem cell research. (lifeissues.net)
See Irving, "Human Embryonic Stem Cell Research: Are official positions based on scientific fraud? (lifeissues.net)
And the MSM (mainstream media), who remain desperately committed to push embryonic stem cell research despite its failures, dangers, and immoral foundations, may soon be reeling at the fall of one of their heroes. (blogspot.com)
embryonic stem cell research has not had a good year. (blogspot.com)
Snuppy was cast under suspicion following revelations that the Korean scientist had fabricated his stem cell research. (blogspot.com)
It brightens the prospects that his team retains the source technologies for stem cell research," Park said. (blogspot.com)
``The patient-matching stem cells no longer exist,'' Roe Jung Hye, dean of research of affairs at the university, said in an e-mailed statement. (blogspot.com)
The university has been conducting a probe on Hwang and his research since Dec. 16, including genetic tests on stem cells being stored at the laboratories. (blogspot.com)
Some cells differentiate to become stem cells which produce tissues and tissues develop to become organs (National Human Genome Research Institute Para 2). (premiumessays.net)
The bill purports to promote stem-cell research, while outlawing the cloning of a human being. (cbc-network.org)
While stem-cell research holds enormous potential for treating or even curing some diseases, the cloning of a human being is morally and ethically unacceptable…Any attempt to clone a human being is in direct conflict with the public policies of this state. (cbc-network.org)
In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)

The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)

PNH is caused by somatic mutations in PIGA (which encodes phosphatidylinositol N-acetylglucosaminyltransferase subunit A) in one or more HSC clones. (medscape.com)
Clinical manifestations of PNH occur when a HSC clone carrying somatic PIGA mutations acquires a growth advantage and differentiates, generating mature blood cells that are deficient of GPI-anchored proteins. (medscape.com)

He did this by using intact nuclei from somatic cells from a Xenopus tadpole. (wikipedia.org)
This was an important extension of work of Briggs and King in 1952 on transplanting nuclei from embryonic blastula cells. (wikipedia.org)

They also reportedly charged $100,000 for each cloned puppy. (wikipedia.org)
Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
The first obstacle to cloning your dog is that $100,000 cost. (wikiquote.org)

The junk biology is flying in the media's descriptions of the now accomplished human cloning. (nationalrighttolifenews.org)

Precise editing is complicated further because two copies of somatic alleles are present in the diploid genome. (nature.com)

Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
Dec. 29, 2005 -- South Korean laboratories used by scientist Hwang Woo Suk no longer have any stem cells created from patients' tissues, the result of the researcher's landmark May 2005 paper, the Seoul National University said. (blogspot.com)
This long-sought technique may eventually let doctors create replacement cells for a wide variety of tissues from bits of a patient's own skin. (nationalrighttolifenews.org)

In 2019, the first Chinese commercially cloned cat, Garlic, was created by Sinogene Biotechnology. (wikipedia.org)

The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)

Because they can propagate indefinitely, as well as give rise to every other cell type in the body (such as neurons, heart, pancreatic, and liver cells), they represent a single source of cells that could be used to replace those lost to damage or disease. (benitonovas.com)
When genome editing induces a phenotypic alteration that is detectable by fluorescence (i.e., cell-surface expression of a target that can be non-lethally assessed with fluorescently labeled antibody), FACS provides a method of enriching edited cells 9 , narrowing the number of clones to propagate and analyze. (nature.com)

The South Korean stem-cell researcher Woo Suk Hwang has been at the centre of one of the largest investigations of scientific fraud in living memory. (nature.com)
With Hwang discredited, both the field of therapeutic cloning and the public's trust in science have suffered a serious setback. (nature.com)
South Korean professor and cloning pioneer Hwang Woo-suk, is in yet more trouble. (blogspot.com)
With this, Hwang demonstrated his team's technical prowess in cloning. (blogspot.com)
Prof. Kong Il-keun at Suncheon University who cloned six cats last summer concurs with Park but the embryologist expressed his regret since Hwang asked for the tests while the SNU team is reviewing the authenticity of Snuppy. (blogspot.com)

Induced pluripotent stem cells, another types of pluripotent stem cells derived from any tissue by reprogramming and are the homologous source of stem cells. (benthamscience.com)
If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)

The non-embryonic stem cells like adult stem cells are in clinical use for many years and embryonic stem cells are now emerging as an alternative source for the same purpose with huge potentials in drug discovery and toxicological studies. (benthamscience.com)
The developments utilizing adult stem cells, however, have been truly amazing with medical treatments (not mere potential or grand promises) already helping thousands of people. (blogspot.com)

WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)

But what is not getting such wide reporting is the use of pluripotent stem cells (as well as many other types of cells and genetic engineering techniques) for reproductive purposes . (lifeissues.net)

In this procedure, the nucleus of an egg cell is removed and replaced by the nucleus of a cell from another adult. (eurostemcell.org)
After being inserted into the egg, the adult cell nucleus is reprogrammed by the host cell. (eurostemcell.org)
The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
The team at OHSU [Oregon Health and Science University], which disclosed its work in a paper published online by Cell, created embryonic stem cells by replacing the nucleus in an unfertilized human egg with the nucleus from a skin cell, then harvesting the resulting stem cells. (nationalrighttolifenews.org)
In sexual reproduction the new individual gets half of its chromosomes from the nucleus of the sperm cell and half from the nucleus of the egg cell. (actionlife.org)
Instead, an egg has its nucleus removed and replaced by a nucleus from another type of cell-a body cell. (actionlife.org)

In sexual reproduction, clones are created when a fertilized egg splits to produce identical (monozygous) twins with identical genomes. (who.int)

Embryonic stem cells (ESCs) can grow infinitely and give rise to all types of cells in human body, thus of tremendous therapeutic potentials for a variety of diseases, such as Parkinson's disease, spinal cord injury, and diabetes. (benthamscience.com)
These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
These cell populations provide platforms to develop new cell-based therapies to treat both malignant and nonmalignant hematological diseases. (benitonovas.com)
Progress in adoptive T-cell therapy for cancer and infectious diseases is hampered by the lack of readily available antigen-specific, human T lymphocytes. (benitonovas.com)

Snuppy, an Afghan hound puppy, was the first dog to be cloned, in 2005 in South Korea. (wikipedia.org)

Millie and Emma were two female Jersey cows cloned at the University of Tennessee in 2001. (wikipedia.org)

Here, we establish a method to enable clonal isolation, selection, and expansion of properly edited cells, using OptoElectroPositioning technology for single-cell manipulation on a nanofluidic device. (nature.com)
Each colony is split and sequentially exported for on-target sequencing and further off-chip clonal expansion of the validated clones. (nature.com)

Therefore, in a given cell, HDR-mediated editing might occur only on one allele while the other allele is either unedited or imprecisely edited by NHEJ-mediated repair. (nature.com)

It defines the term "cloning of a human being" inaccurately. (cbc-network.org)

Therapeutic cloning, which creates embryonic stem cells . (medlineplus.gov)

The term "clone", from the Greek word for twig, denotes a group of identical entities. (who.int)
As such, cloning refers to a procedure via which the production of a baby with a genetic factor that is identical to that of the parents occurs. (premiumessays.net)

The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)

Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)

Anatomy56

Organisms17

Diseases6

Chemicals and Drugs51

Analytical, Diagnostic and Therapeutic Techniques and Equipment58

Phenomena and Processes74

Disciplines and Occupations4

Technology, Industry, Agriculture2

Information Science4

Embryos16

SCNT16

Embryo20

Nuclear11

Blastocyst4

Organism9

Genetically8

Successfully cloned3

Regenerative medicine5

Creation of cloned human1

Mammalian1

Donor8

Pluripotent stem4

Dolly1

Asexual1

Scientists7

Gene3

Derivation1

Hematopoietic stem2

Hwang's6

Germ cells1

Researchers8

Endorsed in 19971

19971

Embryonic state1

Vitro fertilization1

Research19

Organisms2

PIGA2

Nuclei2

100,0003

Biology1

Copies1

Tissues3

Biotechnology1

Therapeutic potential1

Propagate2

Hwang5

Tissue2

Adult stem2

Ethically unacceptable1

Reproductive purposes1

Nucleus6

Genomes1

Diseases5

Afghan1

Cows1

Clonal2

Occur1

Defines1

Creates1

Identical2

Genes1

Species1