Stationary phase in liquid chromatography. Medical search. Frequent questions

Mechanisms of chiral discrimination by these and other types of chiral HPLC phases are discussed in terms of the interactions between functionalitles in the stationary phase and solute enantiomers. (warwick.ac.uk)
Find out here how Bürkert can support you with energy-efficient valves and demand-oriented automation concepts for safe and smooth production, for example in liquid chromatography or high-performance liquid chromatography (HPLC). (burkert.com)
Pichari and Jacob (6) studied the retentive behaviour of some basic drugs using ion-pair high performance liquid chromatography (HPLC) with a system similar to that described. (erowid.org)
Fox (2012) utilized the High Performance Liquid Chromatography (HPLC) according to OECD Guideline 121 / EU Method C.19. (europa.eu)
The test substance interacts with the stationary phase of the cyanopropyl reverse phase HPLC column containing lipophilic and polar moieties. (europa.eu)
The most common form of liquid chromatography in use today is high-performance liquid chromatography (HPLC), which pumps the sample mixture through the column at high pressure. (europeanpharmaceuticalreview.com)
HPLC is the form of liquid chromatography that is generally used in the pharmaceutical industry, as it can provide the precise results that are required. (europeanpharmaceuticalreview.com)
Although expected at first to be used as a complimentary method to gas chromatography, the pharmaceutical industry now almost exclusively uses HPLC as a chromatographic technique. (europeanpharmaceuticalreview.com)
Other forms of HPLC that are used in the pharmaceutical industry include reversed-phase, denaturing and immobilised enzyme reactor (IMER) HPLC. (europeanpharmaceuticalreview.com)
Do you have questions about how high-performance liquid chromatography (HPLC) works? (thermofisher.com)
High-performance liquid chromatography (HPLC) is an analytical chemistry technique used to separate compounds in a chemical mixture. (thermofisher.com)
This whiteboard video provides a brief history of chromatography, and explains the fundamental principles behind HPLC and UHPLC. (thermofisher.com)
Schomburg, G. Polymer-coating approach for HPLC stationary phases: Efficiency, chemical stability, versatility. (mpg.de)
The regio- and stereoselective metabolism of phenanthrene (PA) by seven cDNA-expressed human and five rodent and rabbit cytochromes P-450 has been examined using reverse-phase and chiral stationary phase high-pressure liquid chromatography (HPLC). (nih.gov)
A solid-phase extraction-type collection device packed with Sunpak-H, styrene-divinylbenzene polymer particles, was used to identify 16 airborne polycyclic aromatic hydrocarbons (PAHs) using high-performance liquid chromatography (HPLC)-fluorescence detection and ultraviolet detector. (go.jp)
Optimisation of HPLC systems with different combinations of mobile and stationary phases. (lu.se)
The 2D-HPLC system incorporated strong cation exchange and reversed phase separation modes. (cdc.gov)

the adjustments for supercritical fluid chromatography have been deleted as this technique is not used in any Ph. (edqm.eu)
When conducting analysis with the Nexera UC supercritical fluid chromatography system, because diffusion of the sample band in the mobile phase is high compared with liquid chromatography, separation behavior changes significantly depending on the types of columns used. (shimadzu.com)
Supercritical Fluid Chromatography (SFC): A Powerful. (chromatographytoday.com)
The high separation power and short analysis time obtained demonstrate for the first time that supercritical fluid chromatography is a fast and reliable technique for the analysis of lignin-derived phenols in complex environmental samples. (lu.se)
Alkaline cupric oxide (CuO) oxidation is one of the mostly performance supercritical fluid chromatography (UHPSFC) adopted methods for analyzing lignin in various complex using columns with sub-2 m packing can further improve environmental matrices such as soils and sediments [9]. (lu.se)
UHPSFC , ultra- pacted by other parameters, such as the addition of the mod- high performance supercritical fluid chromatography ifier and the change of the mobile phase density [20]. (lu.se)

It was shown that the retention of solutes by these phases correlated directly with the w/w phase loading, whilst both the separation factor and resolution for various enantiomers displayed a more complex relationship. (warwick.ac.uk)
Temperature is an important separation parameter in reversed-phase high performance liquid chromatography. (utm.my)
In this work, high-temperature high performance liquid chromatography on a carbon-clad zirconia column using water-rich eluent is evaluated as a new approach for the separation of selected triazole fungicides. (utm.my)
Chromatography is the separation of mixtures into their components as a result of differential distribution of the solutes in order for identification, analyses, purify and/or quantity of the mixture for a mobile medium and for a stationary absorbing medium. (majortests.com)
Separation of dried liquid samples with a liquid solvent and a glass plate covered with a thin layer of silica gel. (majortests.com)
What is the basic principle for separation in normal phase, reversed phase, ion-exchange and gel permeation chromatography? (majortests.com)
The involved chemistry relies on basic knowledge of element separation involving radiochemical techniques such as liquid-liquid extraction, ion chromatography, pyrochemistry or precipitation. (psi.ch)
The separation is accomplished using a column coated with a stationary phase. (globenewswire.com)
UHPLC separation of R - and S -enantiomers of Besifloxacin hydrochloride on a new Chiralpak IE-3 column consisting of an immobilized amylose tris(3,5-dichlorophenylcarbamate) chiral stationary phase on 3 µm silica was studied. (springer.com)
The selection and effects of mobile phase solvents, additives, organic modifiers, and column temperature on retention, separation, and resolution were investigated and optimized. (springer.com)
The separation was accomplished under normal-phase conditions using a mobile phase composed of dichloromethane:isopropyl alcohol:trifluoroacetic acid:diethylamine (90:10:0.3:0.05 v/v/v/v) under isocratic mode of elution at 15 °C. The interactions between the analytes, additives, and the stationary phase were discussed and the most probable separation mechanism was proposed. (springer.com)
Mosiashvili L, Chankvetadze L, Farkas T, Chankvetadze B (2013) On the effect of basic and acidic additives on the separation of the enantiomers of some basic drugs with polysaccharide-based chiral selectors and polar organic mobile phases. (springer.com)
1 The separation occurs when the sample interacts with the mobile (liquid) and stationary phases (column). (europeanpharmaceuticalreview.com)
Successful separation only occurs if the analytes have differing affinities for the stationary phase, so selecting the appropriate stationary phase for your compounds is crucial. (thermofisher.com)
Ionic and ionizable compounds typically rely on separation by ion exchange chromatography (IC) or ion pairing reversed-phase chromatography (IP-RPLC). (news-medical.net)
Understanding the characteristics of the compounds being separated and their compatibility with various stationary phases will further optimize separation. (news-medical.net)
Schomburg, G. Gas-and liquid chromatographic separation of naphthalenophanes of the [2.2] and [3.3] type. (mpg.de)
Ionic liquids, which can be tuned by choosing of the cations and anions independently, exhibited unique physicochemical properties, such as tunable miscibility with water and organic solvents, and have potential applications as electrolyte materials, green solvents, catalysts, and separation mediums [ 9 - 14 ]. (hindawi.com)
It shows the possibilities of polysaccharide CSPs have now also been established as the first-choice of chiral phases for enantiomer separation. (intechopen.com)
High-performance liquid chromatography has become the predominant global separation technique over the past four decades. (chromatographytoday.com)
In this study, we reveal the suppression of non-specific hydrophobic interaction in poly(ethylene-co-glycidylmethacrylate) (PEGM) based spongy monolith (SPM), PEGM-SPM, which has recently be reported as a new platform of separation medium for affinity chromatography in our previous study, by an simple acidic treatment. (go.jp)
In the world of analytical chemistry, chromatography has emerged as a cornerstone technique for separation and analysis. (gentechscientific.com)
A chromatography column is the heart of any separation system, where the magic of separation occurs. (gentechscientific.com)
The aim of the course is to enable students to acquire in depth theoretical and practical knowledge of common modern separation techniques, such as chromatography, mass spectrometry and capillary electrophoresis. (lu.se)
A low-viscosity mobile phase consisting of compressed trial organic matter in geosciences because the composition carbon dioxide is used in SFC to achieve fast and efficient of its phenols is an important indicator of the type of original separation. (lu.se)

This supercritical fluid technology is also applicable to the synthesis of important silica intermediates and even to the preparation of chiral stationary phases. (labmate-online.com)
Wen, T. Chiral stationary phases based on lactide derivatives for high-performance liquid chromatography. (beilstein-journals.org)
Liquid chromatography using chiral stationary phases (CSP) proved to be an essential tool with a wide range of applications, including analysis of the stereochemistry of natural compounds. (intechopen.com)

Spectroscopic and thermal analysis and chromatographic performance testing are used to characterise the silica bonded phases. (labmate-online.com)
The relationship between the structure and chromatographic properties of silica is discussed and the preparation and properties of chemically-bonded stationary phases based on silica are reviewed. (warwick.ac.uk)
A detailed account is given of the history of the development of carbohydrate-based stationary phases, including microcrystalline cellulose, other polysaccharides and monosaccharides and their ester and carbamate derivatives, with emphasis on their utility for the chromatographic resolution of enantiomers. (warwick.ac.uk)
In the experimental part, the thesis describes work carried out to study the effects of stationary phase support properties on the chromatographic behaviour and enantiomer resolution capability of carbohydrate carbamate phases. (warwick.ac.uk)
Whilst it is currently common practice to use very wide pore (up to 4000 Angstrom) silicas as supports for carbohydrate carbamate phases, it was concluded from the present work that there is little or no justification for using such supports and that good chromatographic performance and effective chiral discrimination can be achieved on much smaller pore (e. g. 500 Angstrom), higher surface area materials. (warwick.ac.uk)
2. Lippa, K. A. and Sander, L. C., "Identification of isolated cavity features within molecular dynamics simulated chromatographic surfaces," Journal of Chromatography A, 1128, 79-89 (2006). (nist.gov)
This general chapter applies to chromatographic analytical procedures and supplements the general chapters on Thin-layer chromatography (2.2.7) , Gas chromatography (2.2.28) , Liquid chromatography (2.2.29) and Size-exclusion chromatography (2.2.30) . (edqm.eu)
N,N′-diallylimidazolium-based ionic liquids have also been used as extractant to highly enrich organic pollutants from aqueous samples in microextraction techniques, such as dispersed liquid-liquid microextraction and single drop microextraction, or to functionalize the stationary phase of chromatographic column and solid fiber membranes [ 15 - 21 ]. (hindawi.com)
In general, the chromatographic performance and chemical stability of metalized silica-based self-immobilized PMTDS phases were similar to conventional chemically bonded stationary phases. (scielo.br)
By ensuring the removal of contaminants, stabilizing the stationary phase, establishing a stable baseline, and assessing system robustness, column conditioning contributes to the reliability, repeatability, and robustness of chromatographic methods. (gentechscientific.com)

Normal and Reversed Phase Chromatography What is the relationship between polarity of the mobile phase vs. elution time and resolution in normal phase and reversed phase chromatography? (majortests.com)
Secondary forces, such as dipole-dipole, electrostatic, and hydrogen bonding interactions influence this partition, resulting in retention of the compound on the stationary phase or elution in the mobile phase. (news-medical.net)
This contrasts with the order seen in standard reverse-phase chromatography, where elution occurs in the order of least to most hydrophilic. (news-medical.net)

It was found that the standard enthalpy of retention in RPLC (i.e., solute transfer from the mobile phase to the stationary phase) is favorable , due to the large and favorable stationary-phase contribution, which actually overcomes an unfavorable mobile-phase contribution to the enthalpy of retention. (figshare.com)

These separations utilize the pressure-driven flow of a liquid mobile phase through a column packed with a stationary phase. (thermofisher.com)
This stabilization phase is essential for achieving reliable and reproducible separations. (gentechscientific.com)

Ionic liquids (ILs) have become recognized in gas chromatography (GC) as stable and highly polar stationary phases with a wide application range. (chromatographyonline.com)
Moreover, technologically advanced products such as temperature-programmed chip-based GC, GCxGC, and new GC phase including nanoparticles, ionic liquids, and co-polymers are expected to propel the demand for gas chromatography procedures during the forecast period. (globenewswire.com)
1,3-Dialkylimidazolium-based ionic liquids were chemically synthesized and bonded on the surface of magnetic nanoparticles (MNPs) with easy one-step reaction. (hindawi.com)
The obtained six kinds of ionic liquid modified MNPs were characterized with transmission electron microscopy, thermogravimetric analysis, magnetization, and FTIR, which owned the high adsorption capacity due to the nanometer size and high-density modification with ionic liquids. (hindawi.com)
Functionality of MNPs with ionic liquids greatly influenced the solubility of the MNPs with organic solvents depending on the alkyl chain length and the anions of the ionic liquids. (hindawi.com)
In this work, a novel kind of modified MNPs with N,N′-dialkylimidazolium-based ionic liquids containing different alkyl chain lengths and inorganic anions were synthesized by covalent bonding. (hindawi.com)
Six kinds of (3-triethoxysilylpropyl)-4,5-dihydroimidazolium (TIM) ionic liquids, (1-hexyl-3-TIM chloride (HTIMCl), 1-octyl-3-TIM chloride (OTIMCl), 1-decyl-3-TIM chloride (DTIMCl), 1-hexyl-3-TIM hexafluorophosphate (HTIMPF 6 ), 1-octyl-3-TIM hexafluorophosphate (OTIMPF 6 ), and 1-decyl-3-TIM hexafluorophosphate (DTIMPF 6 )) were synthesized (Table 1 ). (hindawi.com)

Mammalian toxicity of munitions compounds: Phase I. Acute oral toxicity, primary skin and eye irritation, dermal sensitization, disposition and metabolism, and Ames tests of additional compounds. (cdc.gov)
Although many drugs had rather long retention times on OV-275, this phase was able to separate structurally similar compounds that were unresolved on the other phases. (erowid.org)
Based on different distribution coefficients of elements or chemical compounds in various media, the liquid-liquid extraction technique has been applied to extract 60 Fe from irradiated Cu samples using HNO 3 /ethyl ether systems [2]. (psi.ch)
Gas chromatography is a chromatography technique that can separate and analyze volatile compounds in gas phase. (globenewswire.com)
It is thus used to separate and detect small molecular weight compounds in the gas phase. (globenewswire.com)
Hydrophilic interaction chromatography (HILIC) is a liquid chromatography technique that is used to separate moderate to highly hydrophilic and polar compounds based on their retention on a hydrophilic stationary phase versus the hydrophilic aqueous polar organic mobile phase. (news-medical.net)
In traditional Reverse-phase Liquid Chromatography (RPLC), polar, hydrophilic and charged compounds are preferentially retained on the column. (news-medical.net)
As such, HILIC effectively retains hydrophilic compounds which are poorly retained in reversed-phase LC. (news-medical.net)
Shim-pack UC series was designed with a variety of stationary phases, making it suitable for analysis of various compounds. (shimadzu.com)
The new ultra-high performance super- critical fluid chromatography method was also applied for the qualitative and quantitative analysis of lignin-derived phenolic compounds obtained upon alkaline cupric oxide oxida- tion of a commercial humic acid. (lu.se)

Bien-Vogelsang, U. Immobilization of stationary liquids on silica particles by γ-radiation. (mpg.de)
This work presents a study of the sorption of a pre-synthesized polysiloxane, poly(methyltetradecylsiloxane) - PMTDS, onto zirconized and titanized-silica particles that results in efficient stationary phases for reversed phase liquid chromatography. (scielo.br)
The self-immobilization of polymer onto titanized silica particles produces more homogeneous polymeric coatings and stationary phases without silanophilic activity. (scielo.br)

Schomburg, G. Characterization and stability of silanized and polymercoated octadecyl reversed phases. (mpg.de)

The goal of this study was to elucidate the roles played by the stationary and mobile phases in retention in reversed-phase liquid chromatography (RPLC) in terms of their individual enthalpic and entropic contribution to the Gibbs free energy of retention. (figshare.com)
This allowed us to examine more fully the contribution that each phase makes to the overall retention. (figshare.com)
Further, the net free energy of retention is favorable due to the favorable enthalpic contribution to retention, which arises from the net interactions in the stationary phase. (figshare.com)
Therefore, to a great extent, retention is due to enthalpically dominated lipophilic interaction of nonpolar solutes with the stationary phase and not from solvophobic processes in the mobile phase. (figshare.com)
These results indicate that the stationary phase plays a very significant role in the overall retention process. (figshare.com)
This is in contrast to the retention mechanism in HILIC, which relies on the partitioning of a compound between the aqueous surface layer of the hydrophilic stationary phase and the organic, hydrophilic compartment of the mobile phase. (news-medical.net)
Zirconized silica-based phases were more chemically resistant, despite their strong retention of basic solutes. (scielo.br)
The retention behavior was compared with that obtained on a commercially-available octadecylsilica (ODS) phase. (go.jp)
The results indicated a significantly larger retentivity of PACs on the PI stationary phase than that on typical ODS stationary phases, where the retention tendency on the PI phase for various PACs having different molecular size and shape was similar to the trend on the ODS phase. (go.jp)
The large retention on the PI phase can be interpreted on the basis of the surface structure of the PI particles, because a number of aromatic functionalities are in the chemical structure of the polymer chain backbone. (go.jp)
By utilizing a three-way ANOVA, the composition of the mobile phase has been shown to have a significant effect on deuterated acetonitrile and other investigated void volume markers, demonstrating the fact that both void volume markers and acetonitrile itself exhibit retention-like behaviour. (lu.se)

Arnold DR, Granvil CP, Ward KW, Proksch JW (2008) Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography-tandem mass spectrometry. (springer.com)
HILIC is highly compatible with mass spectrometry (MS), particularly with electrospray ionization (ESI) interfaces which precede MS. The high polar organic solvent component of the HILIC mobile phase increases the efficiency of ionization in the ESI process. (news-medical.net)
Ionization provides the basis of ESI, which relies on charging the compound of interest in the gas phase and analysis by mass spectrometry. (news-medical.net)
Instrumentation and experimental techniques for high-resolution chromatography as well as linking of chromatography to mass spectrometry and its applications in e.g. food, drug and environmental analysis. (lu.se)

The polymeric coating of inorganic oxide particles has been a strategy for preparation of reversed stationary phases for high-performance liquid chromatography with low cost, good selectivity and high hydrolytic stability. (scielo.br)
Spherical polyimide (PI) particles have been introduced as a stationary phase in liquid chromatography (LC). (go.jp)

Due to the various velocities at which all liquids are pumped through the system, individual components can be separated based on the different flow properties and varying interactions between the stationary and the mobile phases of the substances. (burkert.com)
To determine how variables such as temperature, chain density, chain length, surface interactions, etc., impact the conformational phase behavior of tethered chains. (nist.gov)
To date, we have investigated the impact of surface interactions, chain stiffness, and tethering geometry on conformational phase behavior. (nist.gov)

The mobile phase for gas chromatography is a carrier gas, typically helium due to its low molecular weight and being chemically inert. (globenewswire.com)
To the best of our knowledge, this is the first work about application of the chemically bonded ionic liquid modified MNPs for detecting carcinogenic organic pollutants in environmental water samples. (hindawi.com)

In a separate effort, alkyl stationary phases used in liquid chromatography have been modeled by molecular dynamic simulations, under chromatographically relevant conditions. (nist.gov)

The individual components are separated between a stationary phase (the tubular column in a column) and a mobile phase, which flows through the stationary packing (in this case a liquid). (burkert.com)
The right choice of valve is also an essential factor, as they control and distribute the media both into and out of the chromatography column. (burkert.com)
The sample is transported through the column by the flow of inert, gaseous mobile phase. (majortests.com)
The column itself contains a liquid stationary phase which is absorbed onto the surface of an inert solid. (majortests.com)
This separates liquid samples with a liquid solvent and a column composed of solid beads. (majortests.com)
These models offer insight into selectivity trends observed in liquid chromatography with C18 and C30 stationary phases, prepared by monomeric or polymeric synthetic approaches, and operated at different column temperatures. (nist.gov)
The pressure is applied and the mobile phase moves the analyte through the column. (globenewswire.com)
they will have varying levels of affinity for the mobile phase, resulting in migration through the column at different speeds. (europeanpharmaceuticalreview.com)
The mixed components are placed at the top of the column of the stationary phase, which is generally a fine adsorbent solid such as silica. (europeanpharmaceuticalreview.com)
a component with a higher affinity for the stationary phase will migrate down the column slower than a component which has more affinity for the mobile phase. (europeanpharmaceuticalreview.com)
However, some components may have weak UV chromophores if UV detection is being used or be completely retained on the liquid chromatography column. (europeanpharmaceuticalreview.com)
in gas chromatography , the conditions for adjustment of the column dimensions, injection volume, split ratio, injection port and transfer-line temperatures (the latter two being new for Ph. (edqm.eu)
However, amidst the complexity of method development and validation, there is one critical step that often goes unnoticed or receives insufficient attention: chromatography column conditioning. (gentechscientific.com)
Column conditioning involves a series of preparatory steps to stabilize the stationary phase, remove unwanted contaminants, and establish a consistent flow profile. (gentechscientific.com)
Column conditioning plays a vital role in this phase, primarily because it lays the foundation for subsequent experiments. (gentechscientific.com)
Stationary Phase Stabilization: A fresh column contains an active, but potentially unstable, stationary phase. (gentechscientific.com)
Conditioning the column helps to stabilize the phase, ensuring its uniform distribution and consistent performance over time. (gentechscientific.com)
Chromatography column conditioning stands as an essential step in method development and validation, often overlooked but indispensable for success. (gentechscientific.com)
MATERIALS AND METHODS: Dowex® 50WX4 hydrogen form resin was used for column chromatography to prepare INM-A. To track alkaloids, INM-A was conducted with Dragendorff's, Mayer's, and Wagner's reagents. (bvsalud.org)
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. (bvsalud.org)
For a water:acetonitrile mobile phase, the minor disturbance method using deuterated acetonitrile to obtain an integral average void volume (2.08 and 2.05 mL for C18 at 30 and 40 °C, respectively and 2.16 and 2.13 mL for C8 at 30 and 40 °C, respectively) was found to be the most appropriate method for determining the elusive column void volume. (lu.se)

Representation of octadecyl stationary phase morphology showing an ordered state and a disordered state. (nist.gov)

Examples of when chromatography is used are in pharmaceutical companies in order to find out the amount of chemicals used in each new product, hospitals for detection of sugar/blood levels and law enforcement for comparisons of samples found at a crime scene. (majortests.com)
In contrast, advancement in gas chromatography columns for petrochemical applications, adoption of gas chromatography in R&D for cancer detection are some of the factors expected to offer lucrative growth opportunities for players in the chromatography market. (globenewswire.com)
Mass spectrometric detection for quantitative and qualitative analysis connected to both gas and liquid chromatography. (lu.se)

This article presents specific properties of IL phase capillary GC columns, including polarity scale and inner surface morphologies of IL columns. (chromatographyonline.com)
Gas chromatography with capillary columns and different injection techniques. (lu.se)

Depending on stationary phase used in this analytical technique, there are two types of gas chromatography: gas-liquid chromatography (GLC) and gas-solid chromatography (GSC). (globenewswire.com)
Liquid chromatography is an analytical technique utilised widely in the pharmaceutical industry. (europeanpharmaceuticalreview.com)
Liquid chromatography is an analytical technique that is used to separate a certain sample into its individual components. (europeanpharmaceuticalreview.com)

The precise and safe purification of substances using chromatography is an essential step in the manufacture of fine chemicals. (burkert.com)
Schomburg, G. Purification and analysis of partially alkylated cyclodextrins by liquid and gas chromatography. (mpg.de)

Task 2 Chromatography analysis: Thin layer chromatography Chromatography is used to separate mixtures of substances in to components. (majortests.com)
can test substances that are heat sensitive unlike gas chromatography. (boredofstudies.org)

The experimental approach involved measuring standard enthalpies of transfer of alkylbenzenes from typical mobile phases used in RPLC (methanol/water and acetonitrile/water mixtures), as well as from n -hexadecane (a simple analogue of the stationary phase) to the gas phase, using high-precision headspace gas chromatography. (figshare.com)

Schomburg, G. Stationary phases for reversed-phase liquid chromatography: Coating of silica by polymers of various polarities. (mpg.de)
Another possibility for preparation of the polymer-coated stationary phases with pre-synthesized polymers has been by the self-immobilization process. (scielo.br)

The dual composition of the stationary phase, having polar and non-polar sites allows for interaction of polar and non-polar groups of the test substance in a similar way as it is the case for organic matter in soil or sewage sludge matrices. (europa.eu)
Improvement in the selection of a stationary phase based on composition is one area that is being developed. (news-medical.net)

The other four carbamate phases all showed resolving ability, each with its own specific pattern of solute selectivity. (warwick.ac.uk)
Development of a Stationary Phase Optimised Selectivity Liquid Chromatography based screening method for adulterations of food supplements for the treatment of pain. (sciensano.be)
In this paper Stationary Phase Optimised Selectivity Liquid Chromatography was used for the development of a screening method for nine analgesics, codeine and caffeine, often present in this type of dietary supplements. (sciensano.be)

Specifically, Physical Optics Corporation will fabricate and test a solid-state filter tailored to precisely match the spectral characteristics of target compound(s), either gaseous or liquid, in the near-infrared region of the electromagnetic spectrum. (nsf.gov)

Thermodynamic studies of a zwitterionic stationary phase in hydrophilic interaction liquid chromatography. (illumina.com)

Dublin, Oct. 06, 2022 (GLOBE NEWSWIRE) -- The "Gas Chromatography Market By Product, By End User: Global Opportunity Analysis and Industry Forecast, 2021-2031" report has been added to ResearchAndMarkets.com's offering. (globenewswire.com)
According to this report the gas chromatography market was valued at $1.7 billion in 2021, and is estimated to reach $3.2 billion by 2031, growing at a CAGR of 6.1% from 2022 to 2031. (globenewswire.com)
This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the gas chromatography market analysis from 2021 to 2031 to identify the prevailing gas chromatography market opportunities. (globenewswire.com)

gas-liquid chromatography - high performance liquid chromatography so i know how both of them work, pretty much, but what is the value of them? (boredofstudies.org)
How does gas and high performance liquid chromatography work? (boredofstudies.org)
However, high cost of gas chromatography equipment and lack of adequate skilled professionals to operate gas chromatography instruments and perform the techniques in the pharmaceutical industry may hamper the growth of the market. (globenewswire.com)
The objectives of Phase I are (1) to construct a proof-of-principle generator for operation at 125 kV, (2) to experimentally demonstrate that a uniform, high energy ion beam can be generated, and (3) to develop the conceptual design for a Phase II laboratory prototype DNG system. (nsf.gov)
Wang Z, Wang S, Zhu F, Chen Z, Yu L, Zeng S (2012) Determination of enantiomeric impurity in besifloxacin hydrochloride by chiral high-performance liquid chromatography with precolumn derivatization. (springer.com)
Journal of High Resolution Chromatography 1993 , 16 , 587-593. (mpg.de)
Journal of High Resolution Chromatography 1992 , 15 , 579-584. (mpg.de)
Shim-pack UC series offers various stationary phases suitable for the mobile phase of high diffusion and low-viscosity liquid carbon dioxide. (shimadzu.com)
Laboratory sessions (7.5 credits): Experimental techniques for high-resolution chromatography. (lu.se)

The comparison of void volumes, obtained with conventional neutral void volume markers, revealed the former to be 24-36% lower than the void volume obtained using deuterated acetonitrile, as an isotopically labelled mobile phase component. (lu.se)

MNPs coated with ionic liquid were applied to preconcentrate polycyclic aromatic hydrocarbons (PAHs) in water samples through forming mixed hemimicelles on the surface of MNPs. (hindawi.com)

Chromatography allows us to separate complex media mixtures with great precision. (burkert.com)

A novel method for the preparation of stationary phases has been developed, using a green chemistry approach that avoids the use of problematic organic solvents. (labmate-online.com)
She received her Ph.D. in analytical chemistry from Florida State University and completed a National Research Council postdoctoral fellowship at the National Institute of Standards and Technology (NIST) studying stationary phases for liquid chromatography. (nist.gov)

Similarly, 210 Po may be extracted from liquid Pb-Bi alloy using molten NaOH at temperatures exceeding 300 °C (non-aqueous pyrometallurgical liquid-liquid extraction) [3]. (psi.ch)

By exploiting properties of supercritical carbon dioxide (sc-CO2), such as solvating power and enhanced diffusivity, organosilanes are reacted with surface silanol groups, for a clean, solvent-free preparation of highly efficient silica bonded phases for liquid chromatography (LC), such as octadecylsilica, fluorinated octylsilica and pentafluorophenylpropyl phases (1). (labmate-online.com)
Paper chromatography is when it separates liquid samples with a liquid solvent and a paper strip. (majortests.com)
The thin layer chromatography plate is out into a beaker containing the solvent but making sure that the solvent is below the pencil line. (majortests.com)

The sorbed materials, after 6 days at room temperature without any chemical or physical agent, denominated as self-immobilized stationary phase, present appropriate polymeric layer thicknesses that cover the metalized silica surfaces. (scielo.br)

However, it has been noted that the coating of ionic liquid is noncovalent, which means that ionic liquid is more easily desorbed from surface and preconcentration of organic pollutants is strongly affected by the extraction parameters. (hindawi.com)
Selecting an organic modifier for reversed-phase chr. (chromatographytoday.com)

How is liquid chromatography used in the pharmaceutical industry? (europeanpharmaceuticalreview.com)
From pharmaceutical development to environmental monitoring, scientists and lab technicians rely on chromatography to obtain accurate and reliable results. (gentechscientific.com)

Predicting how the conformational phase behavior of tethered chain molecules depends on external variables is challenging. (nist.gov)
We have investigated the conformational phase behavior of tethered chain systems using temperature expanded Monte Carlo techniques at thousands of state points, covering densities from the isolated chains to the thin film limit, and a broad range of temperatures. (nist.gov)
We have demonstrated that simulation may be used as an effective guide to understanding the conformational phase behavior of tethered chain systems. (nist.gov)

Journal of chromatography. (illumina.com)
"Identification of Major Drugs of Abuse Using Chromatography:-An Update" Journal of Chromotograhpic Science . (erowid.org)
Journal of Chromatography A, 694, 3-13. (scirp.org)
Journal of Chromatography A 1991 , 540 , 53-76. (mpg.de)
Journal of Chromatography A 1986 , 351 , 393-408. (mpg.de)
Journal of Chromatography A 1983 , 282 , 27-39. (mpg.de)

Molecular dynamics simulations of alkylsilane stationary-phase order and disorder. (nist.gov)
Ersoz, A., Diltemiz, S.E., Ozcan, A.A. and Denizli, A. (2008) Synergie between Molecular Imprinted Polymer Based on Solid-Phase Extraction and Quartz Crystal Microbalance Technique for 8-OHdG Sensing. (scirp.org)

Stationary phase order was found to increase with increased bonding density, increased chain length, and at decreased temperature. (nist.gov)

Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix. (bvsalud.org)

In addition, the media in conventional valve distributors have a longer distance to travel, which prolongs the chromatography process. (burkert.com)

In the development phase, verification procedures involve performing special tests to model or simulate a portion, or the entirety, of a product, service, or system, then performing a review or analysis of the modeling results. (wikipedia.org)
In the post-development phase, verification procedures involve regularly repeating tests devised specifically to ensure that the product, service, or system continues to meet the initial design requirements, specifications, and regulations as time progresses. (wikipedia.org)
It is a process that is used to evaluate whether a product, service, or system complies with regulations, specifications, or conditions imposed at the start of a development phase. (wikipedia.org)
This Small Business Innovation Research Phase I project involves research on development and application of an optical data acquisition system, I/O devices, and optical data analysis and recognition. (nsf.gov)
Specifically, an optical security system embodying phase-encoding will be conceptualized as encryption means in conjunction with biometric measurements, with the general objective of producing an automatic, tamper-proof security system. (nsf.gov)
The concept will be rapidly prototyped for a proof-of-concept experiment, for feasibility evaluation, and for providing a preliminary design and demonstration plan for Phase II, which will involve development, building, and testing of a brass-board model of the optical security system. (nsf.gov)
This Small Business Innovation Research Phase I project will demonstrate a new class of optical devices that will form the heart of a low-cost, versatile, field-usable environmental monitoring system to be developed in Phase II. (nsf.gov)
It also describes the essential components, or modules, of a chromatography system. (thermofisher.com)

This was the only stationary phase to separate cocaine from methaqualone. (erowid.org)

A review of the application of chromatography to the analysis of drugs of abuse was recently published (1), covering the period up to 1980. (erowid.org)
In-depth analysis of the gas chromatography market segmentation assists to determine the prevailing market opportunities. (globenewswire.com)
The report includes the analysis of the regional as well as global gas chromatography market trends, key players, market segments, application areas, and market growth strategies. (globenewswire.com)

Anatomy8

Organisms15

Chemicals and Drugs106

Analytical, Diagnostic and Therapeutic Techniques and Equipment61

Phenomena and Processes58

Disciplines and Occupations6

Technology, Industry, Agriculture5

Information Science4

Health Care8

HPLC17

Supercritical fluid chromato6

Separation25

Chiral stationary phases3

Chromatographic10

Elution3

Solute transfer from the mobile1

Separations2

Ionic liquids7

Compounds10

Silica particles3

Characterization1

Retention11

Mass spectrometry4

Particles2

Interactions3

Chemically2

Alkyl1

Column21

Octadecyl1

Detection3

Capillary2

Analytical technique3

Purification2

Substances2

RPLC1

Polymers2

Composition2

Selectivity3

Gaseous1

Hydrophilic1

20213

High9

Acetonitrile1

Polycyclic aromatic hyd1

Mixtures1

Chemistry2

Aqueous1

Solvent3

Polymeric1

Organic2

Pharmaceutical2

Behavior3

Journal6

Molecular2

Temperature1

Inert solid1

Conventional1

System8

Separate1

Analysis3