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  • SUMO1
  • The intensities of protein bands corresponding to SUMO1 or -2/3 quantitated from Western blots as in panel A were normalized to their respective loading control and expressed relative to the levels in uninduced cells (1.0). (nih.gov)
  • PMID
  • The SAF-A protein is cleaved by caspase-3 during apoptosis [ PMID: 10671544 ]. (ebi.ac.uk)
  • They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), however they are now recognised to bind DNA, RNA, protein and/or lipid substrates [ PMID: 10529348 , PMID: 15963892 , PMID: 15718139 , PMID: 17210253 , PMID: 12665246 ]. (ebi.ac.uk)
  • Miz1 binds to the homeobox protein Msx2, enhancing the specific DNA-binding ability of Msx2 [ PMID: 9256341 ]. (ebi.ac.uk)
  • motifs
  • They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. (ebi.ac.uk)
  • sequence
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • Miz1 is a sequence specific DNA binding protein that can function as a positive-acting transcription factor. (ebi.ac.uk)
  • Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PIASy. (novusbio.com)
  • regulation
  • Numerous immunomodulatory signals are concurrently involved in the regulation of bone metabolism and vice versa bone-derived proteins, such as osteopontin, may have immunomodulatory effects ( 5 ). (jimmunol.org)
  • cellular
  • 3 4 5 6 7 Retinoschisin is almost entirely composed of a highly conserved discoidin domain frequently found in a wide range of membrane and extracellular proteins and most likely mediating cell adhesion and cellular signaling processes. (arvojournals.org)
  • Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response. (nih.gov)
  • EYFP.PIAS4 protein levels increased substantially with time, without considerable alteration to endogenous PIAS4 expression (Fig. 3C and D). As noted in other studies, however, high levels of ectopic PIAS4 had detrimental cellular effects (66, 68). (nih.gov)
  • encodes
  • 2 It encodes a 24-kDa protein, termed retinoschisin, which is mainly secreted from photoreceptors as a homo-oligomeric complex. (arvojournals.org)
  • predicted molecular
  • Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. (novusbio.com)