Models, MolecularNucleic Acid ConformationCircular DichroismProtein Structure, SecondaryThermodynamicsMolecular Sequence DataProtein FoldingProtein ConformationCalorimetry, Differential ScanningBase SequenceAmino Acid SequenceMagnetic Resonance SpectroscopyBinding SitesHydrogen BondingProtein Structure, TertiaryTemperatureProtein BindingEscherichia coliComputer SimulationStructure-Activity RelationshipElectrophoresis, Polyacrylamide GelKineticsAngina, StableDrug StabilityTime FactorsIsotope LabelingCell LineIsotopesAngina PectorisMutationTransfectionHydrogen-Ion ConcentrationPlasmidsTreatment OutcomeEnzyme StabilityRecombinant ProteinsGenetic VectorsDNAProtein StabilityRNA, MessengerModels, BiologicalHot TemperatureCloning, MolecularTranscription, GeneticRecombinant Fusion ProteinsCells, CulturedProtein DenaturationBacterial ProteinsFollow-Up StudiesDose-Response Relationship, DrugDimerizationMolecular WeightPeptidesMass SpectrometryProspective StudiesDNA-Binding ProteinsGene ExpressionHeLa CellsMacromolecular SubstancesReproducibility of ResultsPhenotypePromoter Regions, GeneticProteinsCricetinaeMolecular StructureDNA PrimersGreen Fluorescent ProteinsChromatography, High Pressure LiquidPeptide FragmentsOxygen IsotopesBiological MarkersCell Line, TumorSolubilityCoronary Artery DiseaseRNAMutagenesis, Site-DirectedHydrolysisGene Expression RegulationOxidation-ReductionChromatography, GelDrug Administration ScheduleTransformation, GeneticSubstrate SpecificityDisease ProgressionCattleWaterTranscription FactorsTumor Cells, CulturedSaccharomyces cerevisiaeZinc IsotopesCarrier ProteinsMembrane ProteinsSequence Homology, Amino AcidAmino AcidsBlotting, WesternRabbitsProtein EngineeringModels, ChemicalDNA, BacterialCell Membrane